David M. Shackleford

Australian Regenerative Medicine Institute

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 8 papers. Top paper: “Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria”.

Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00311

N/A

0DataRank · unranked

37 citations

Xiaoyi Deng, Karen L. White, Farah El Mazouni, John White, David M. Shackleford +24 more

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00173

N/A

0DataRank · unranked

47 citations

Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey I. Gerasyuto, Sreekanth Kokkonda +39 more

Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones

Malaria Journal(2021)10.1186/s12936-021-03617-1

N/A

0DataRank · unranked

23 citations

Fangyi Zhu, Jared T. Hammill, Gloria Holbrook, Lei Yang, Burgess B. Freeman +7 more

Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones

Research Square (Research Square)(2021)10.21203/rs.3.rs-60168/v2

N/A

0DataRank · unranked

0 citations

Fangyi Zhu, Jared T. Hammill, Gloria Holbrook, Lei Yang, Burgess Freeman +8 more

Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02394

N/A

0DataRank · unranked

11 citations

Roger V. Bonnert, Jet Tsien, Xiaoyi Deng, Chris Higgs, Farah El Mazouni +39 more

Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria

Cell chemical biology(2024)10.1016/j.chembiol.2024.07.001

N/A

0DataRank · unranked

15 citations

Suraksha Gahalawat, S. Ray, Nhi Ho, Yan Han, Kurt E. Ward +29 more

Optimization of species-selective reversible proteasome inhibitors for the treatment of malaria

ChemRxiv(2025)10.26434/chemrxiv-2025-f64v2

N/A

0DataRank · unranked

0 citations

S. Ray, Xiaoyu Zhang, Xiaoyi Deng, Yan Han, Aloysus K. Lawong +21 more

Optimization of species-selective reversible proteasome inhibitors for the treatment of malaria

ChemRxiv(2025)10.26434/chemrxiv-2025-f64v2-v2

N/A

0DataRank · unranked

0 citations

S. Ray, Xiaoyu Zhang, Xiaoyi Deng, Yan Han, Zhe Chen +22 more