Bo Wen

Heilongjiang University of Chinese Medicine

Also affiliated with Chinese Academy of Medical Sciences & Peking Union Medical College, University of Michigan, University of Jinan, Integrated Chinese Medicine (China), Michigan United, Michigan Cancer Research Consortium, Ministry of Agriculture and Rural Affairs, Third People's Hospital of Hefei, Shenzhen Pingle Orthopedic Hospital, Henan Institute of Science and Technology, Northwest A&F University, South China University of Technology, Xinjiang University

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 20 papers. Top paper: “Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.”.

Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.

Journal of Clinical Investigation(2020)10.1172/jci129126

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142 citations

Hongzhi Miao, Katarzyna Kempińska, Tao Wu, Trupta Purohit, Eungi Kim +30 more

Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.113060

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15 citations

Edward Grimley, Mikhail Chtcherbinine, Cameron D. Buchman, Cyrus Takahashi, Bikash Debnath +12 more

Synthesis and structure-activity relationships of thieno[2,3-d]pyrimidines as atypical protein kinase C inhibitors to control retinal vascular permeability and cytokine-induced edema

Bioorganic & Medicinal Chemistry(2020)10.1016/j.bmc.2020.115480

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2 citations

Michael W. Wilson, Kun Liu, Pil H. Lee, Larisa Yeomans, Susan E. Hagen +7 more

Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00900

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142 citations

Lijie Zhao, Xin Han, Chong Qin, Bukeyan Miao, Donna McEachern +10 more

Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00882

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139 citations

Lijie Zhao, Weiguo Xiang, Chong Qin, Bukeyan Miao, Donna McEachern +8 more

Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity

Nature Communications(2021)10.1038/s41467-021-23152-6

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43 citations

Jing Deng, Hao Li, Hongzhi Miao, Dmitry Borkin, Trupta Purohit +25 more

Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation

EBioMedicine(2021)10.1016/j.ebiom.2021.103725

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37 citations

Yanhong Guo, Huilun Wang, Minzhi Yu, Kristen Hong, Dan Li +10 more

Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis

Redox Biology(2022)10.1016/j.redox.2022.102313

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53 citations

Yuhao Liu, Alexandra C Finney, Alia Ghrayeb, Ying Zhao, Yousef Shukha +19 more

IDOL deficiency inhibits cholesterol-rich diet-induced atherosclerosis in rabbits

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.03.490218

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1 citations

Ying Yu, Yanhong Guo, Dongshan Yang, Jun Song, Jie Xu +12 more

GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress

Cancer Discovery(2023)10.1158/2159-8290.cd-23-0437

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63 citations

Zitong Zhao, Angelica Lin, John Z. Yang, Jie Xu, Kari Wilder-Romans +35 more

Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00405

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58 citations

Lijie Zhao, Weiguo Xiang, Bukeyan Miao, Chong Qin, Mi Wang +16 more

Perinatal Azithromycin Provides Limited Neuroprotection in an Ovine Model of Neonatal Hypoxic-Ischemic Encephalopathy

Stroke(2023)10.1161/strokeaha.123.043040

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14 citations

Yasmine White, Rachel S. Hutchings, Christian Vento, Janica Ha, Hadiya Manzoor +19 more

Prophylactic Mitigation of Acute Graft versus Host Disease by Novel 2-(Pyrrolidin-1-ylmethyl)pyrrole-Based Stimulation-2 (ST2) Inhibitors

ACS Pharmacology & Translational Science(2023)10.1021/acsptsci.3c00122

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5 citations

Hua Jiang, Denggang Fu, Jason C. Rech, Aaron M. Robida, Krishani Rajanayake +10 more

A Phase 0 Study Assessing the Intracranial Activity of a Metabolic Radiosensitizer in Patients with Glioblastoma

International Journal of Radiation Oncology*Biology*Physics(2023)10.1016/j.ijrobp.2023.06.872

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0 citations

Wajd N. Al‐Holou, A. Scott, Bernard L. Marini, Ahna L. H. Pai, Bo Wen +6 more

Discovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01946

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24 citations

Haibin Zhou, Longchuan Bai, Donna McEachern, Dimin Wu, Ranjan Kumar Acharyya +12 more

Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01521

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21 citations

Rohan Kalyan Rej, Biao Hu, Zhixiang Chen, Dimin Wu, Jianfeng Lü +18 more

Structure-Based Development of Novel Spiro-Piperidine ASH1L Inhibitors

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01673

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5 citations

Rhiannon Stevens, Devon G. Hucek, Trupta Purohit, Shuangjiang Li, Hongzhi Miao +10 more

Proteolysis-targeting vaccines (PROTAVs) for robust combination immunotherapy of melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.01.616069

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0 citations

Ting Su, Furong Cheng, Shurong Zhou, Xiang Liu, Mi Wang +15 more

IDOL Deficiency Inhibits Cholesterol-Rich Diet–Induced Atherosclerosis in Rabbits

Arteriosclerosis Thrombosis and Vascular Biology(2025)10.1161/atvbaha.125.322417

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3 citations

Ying Yu, Manabu Niimi, Yanhong Guo, Dongshan Yang, Jun Song +17 more

Correction to “Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer”

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00592

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1 citations

Rohan Kalyan Rej, Biao Hu, Zhixiang Chen, Dimin Wu, Jianfeng Lü +18 more