María Elena Bottazzi

Also affiliated with Baylor College of Medicine, Texas Children's Hospital, Hospital for Tropical Diseases

Immunology and MicrobiologyMedicineEnvironmental Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 53 papers. Top paper: “Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity”.

Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.20.444848

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0.396DataRank · unranked

13 citations

Francesco Borriello, Timothy R. O’Meara, Marisa E. McGrath, Yoshine Saito, Robert Haupt +37 more

Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with aluminum hydroxide induces protective immunity and reduces immune enhancement

Vaccine(2020)10.1016/j.vaccine.2020.09.061

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108 citations

Xinrong Tao, Anurodh Shankar Agrawal, Abdullah Algaissi, Bi-Hung Peng, Jeroen Pollet +8 more

Host Immunity and Inflammation to Pulmonary Helminth Infections

Frontiers in Immunology(2020)10.3389/fimmu.2020.594520

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56 citations

Pedro Henrique Gazzinelli-Guimarães, John Knight, Ricardo Toshio Fujiwara, Peter J. Hotez, María Elena Bottazzi +2 more

A scalable and reproducible manufacturing process for Phlebotomus papatasi salivary protein PpSP15, a vaccine candidate for leishmaniasis

Protein Expression and Purification(2020)10.1016/j.pep.2020.105750

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19 citations

Rakhi Kundu, Surafel Damena, Amadeo B. Biter, Mun Peak Nyon, Wen‐Hsiang Chen +5 more

Coronavirus vaccine-associated lung immunopathology-what is the significance?

Microbes and Infection(2020)10.1016/j.micinf.2020.06.007

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19 citations

Ulrich Strych, Peter J. Hotez, David B. Corry, María Elena Bottazzi

TLR4 agonist protects against Trypanosoma cruzi acute lethal infection by decreasing cardiac parasite burdens

Parasite Immunology(2020)10.1111/pim.12769

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17 citations

Julio Vladimir Cruz-Chan, Leroy Versteeg, Christian Teh‐Poot, Kristyn Hoffman, April Kendricks +7 more

Safety and immunogenicity of a recombinant vaccine against Trypanosoma cruzi in Rhesus macaques

Vaccine(2020)10.1016/j.vaccine.2020.05.010

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35 citations

Claudia Herrera, Weihong Tu, Kelly Goff, Marissa Fahlberg, Erin Haupt +6 more

Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1) Formulated with Aluminum Hydroxide Induces Protective Immunity and Reduces Immune Enhancement

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.15.098079

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38 citations

Xinrong Tao, Anurodh Shankar Agrawal, Abdullah Algaissi, Bi‐Hung Peng, Jeroen Pollet +8 more

SARS-CoV-2 RBD219-N1C1: A Yeast-Expressed SARS-CoV-2 Recombinant Receptor-Binding Domain Candidate Vaccine Stimulates Virus Neutralizing Antibodies and T-cell Immunity in Mice

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.04.367359

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26 citations

Wen‐Hsiang Chen, Leroy Versteeg, Brian Keegan, Bin Zhan, Junfei Wei +15 more

Process Development and Scale-up Optimization of the SARS-CoV-2 Receptor Binding Domain-Based Vaccine Candidate, RBD219-N1C1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.30.424829

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6 citations

Zhuyun Liu, Wen‐Hsiang Chen, Junfei Wei, Rakhi Kundu, Rakesh Adhikari +7 more

SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice

Human Vaccines & Immunotherapeutics(2021)10.1080/21645515.2021.1901545

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100 citations

Wen‐Hsiang Chen, Leroy Versteeg, Brian Keegan, Bin Zhan, Junfei Wei +15 more

A yeast-expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates

Science Immunology(2021)10.1126/sciimmunol.abh3634

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83 citations

Talha Abid, Susan Pereira Ribeiro, Venkata Viswanadh Edara, Katharine Floyd, Justin C. Smith +42 more

Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate

Biochimica et Biophysica Acta (BBA) - General Subjects(2021)10.1016/j.bbagen.2021.129893

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71 citations

Junfei Wei, Rakhi Kundu, Rakesh Adhikari, Zhuyun Liu, Jungsoon Lee +13 more

Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi

Frontiers in Cellular and Infection Microbiology(2021)10.3389/fcimb.2021.614665

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54 citations

Louisa A. Messenger, Michael D. Lewis, Matthew Yeo, João Luís Reis-Cunha, Gabriel Machado Matos +21 more

The Benefits of Vaccinating With the First Available COVID-19 Coronavirus Vaccine

American Journal of Preventive Medicine(2021)10.1016/j.amepre.2021.01.001

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41 citations

Kelly J. O’Shea, Patrick T. Wedlock, Ulrich Strych, Marie C. Ferguson, María Elena Bottazzi +6 more

Vaccine-linked chemotherapy induces IL-17 production and reduces cardiac pathology during acute Trypanosoma cruzi infection

Scientific Reports(2021)10.1038/s41598-021-82930-w

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36 citations

Liliana Villanueva‐Lizama, Leroy Versteeg, Ashish Damania, María José Villar, Cristina González‐López +7 more

Transient Ascaris suum larval migration induces intractable chronic pulmonary disease and anemia in mice

PLoS neglected tropical diseases(2021)10.1371/journal.pntd.0010050

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24 citations

Evan Li, Morgan Knight, Grace Adeniyi-Ipadeola, Lizhen Song, Alan R. Burns +5 more

Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice

npj Vaccines(2021)10.1038/s41541-020-00276-2

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20 citations

Jessica A. Hess, Fernando Pardo‐Manuel de Villena, Benjamin E. Leiby, Ayako Shimada, Yu Lei +8 more

Signal Transducer and Activator of Transcription-3 Modulation of Cardiac Pathology in Chronic Chagasic Cardiomyopathy

Frontiers in Cellular and Infection Microbiology(2021)10.3389/fcimb.2021.708325

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18 citations

María José Villar, Cristina Poveda, María Elena Bottazzi, Peter J. Hotez, David J. Tweardy +2 more

Location and expression kinetics of Tc24 in different life stages of Trypanosoma cruzi

PLoS neglected tropical diseases(2021)10.1371/journal.pntd.0009689

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11 citations

Rakesh Adhikari, Cristina Poveda, Maria Jose Villar-Mondragon, Kathryn M. Jones, Peter J. Hotez +4 more

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.06.451353

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9 citations

Ulrich Strych, Wen‐Hsiang Chen, Leroy Versteeg, Brian Keegan, Bin Zhan +17 more

Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain, RBD203-N1 as a COVID-19 Protein Vaccine Candidate

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.24.457518

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1 citations

Jeroen Pollet, Ulrich Strych, Jungsoon Lee, Zhuyun Liu, Rakhi Kundu +14 more

An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice.

Science Translational Medicine(2022)10.1126/scitranslmed.abj5305

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69 citations

Francesco Borriello, Timothy R. O’Meara, Marisa E. McGrath, Yoshine Saito, Robert Haupt +41 more

Past, present, and future of Lyme disease vaccines: antigen engineering approaches and mechanistic insights

Expert Review of Vaccines(2022)10.1080/14760584.2022.2102484

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21 citations

Ulrich Strych, María Elena Bottazzi, Yi‐Pin Lin, Wen‐Hsiang Chen

Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With Onchocerca ochengi

Frontiers in Cellular and Infection Microbiology(2022)10.3389/fcimb.2022.869039

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17 citations

María Elena Bottazzi, Peter J. Hotez, Sara Lustigman, Bin Zhan

Co-Administration of Adjuvanted Recombinant Ov-103 and Ov-RAL-2 Vaccines Confer Protection against Natural Challenge in A Bovine Onchocerca ochengi Infection Model of Human Onchocerciasis

Vaccines(2022)10.3390/vaccines10060861

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11 citations

Germanus S. Bah, Ndode Herman Okah-Nnane, Catherine Hartley, Alexandra F. Glover, Tessa R. Walsh +15 more

Mucosal Vaccination With Recombinant Tm-WAP49 Protein Induces Protective Humoral and Cellular Immunity Against Experimental Trichuriasis in AKR Mice

Frontiers in Immunology(2022)10.3389/fimmu.2022.800295

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7 citations

Venkatesh L. Hegde, Ananta V. Yanamandra, Madison P. O’Hara, Brian Keegan, Kathryn M. Jones +6 more

CspZ FH-binding sites as epitopes promote antibody-mediated Lyme borreliae clearance

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.24.493343

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0 citations

Ashley L. Marcinkiewicz, Tristan A. Nowak, Rakhi Kundu, Zhuyun Liu, Ulrich Strych +4 more

Vaccines and therapeutics for immunocompromised patients with COVID-19

EClinicalMedicine(2023)10.1016/j.eclinm.2023.101965

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119 citations

Carolina Batista, Yanis Ben Amor, Önder Ergönül, Mazen Hassanain, Peter J. Hotez +12 more

From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access

Expert Review of Vaccines(2023)10.1080/14760584.2023.2217917

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32 citations

Rakesh Adhikari, Wen‐Hsiang Chen, Yilin Chen, Portia M. Gillespie, Nelufa Islam +18 more

Heterologous mRNA-protein vaccination with Tc24 induces a robust cellular immune response against Trypanosoma cruzi, characterized by an increased level of polyfunctional CD8+ T-cells

Current Research in Immunology(2023)10.1016/j.crimmu.2023.100066

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28 citations

Ana Carolina Leão, Chiara Mancino, Francesca Taraballi, Yilin Chen, Rakesh Adhikari +10 more

Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease

Frontiers in Cellular and Infection Microbiology(2023)10.3389/fcimb.2023.1106315

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19 citations

Elise N. Mangin, Corey Reynolds, Liliana E. Villanueva, Julio Vladimir Cruz, Leroy Versteeg +7 more

SARS-CoV-2 triggers Dickkopf-1 (Dkk-1) modulation of T helper cells and lung pathology in mice

Genes & Diseases(2023)10.1016/j.gendis.2023.101167

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18 citations

Freedom M. Green, Stephen A. Shaw, Lauren J. Bonilla, Shannon E. Ronca, María Elena Bottazzi +3 more

Localized cardiac small molecule trajectories and persistent chemical sequelae in experimental Chagas disease

Nature Communications(2023)10.1038/s41467-023-42247-w

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16 citations

Rebecca Ulrich vonBargen, April Kendricks, Kate Wheeler, Ana Carolina Leão, Krithivasan Sankaranarayanan +9 more

A short-term method to evaluate anti-leishmania drugs by inhibition of stage differentiation in Leishmania mexicana using flow cytometry

Experimental Parasitology(2023)10.1016/j.exppara.2023.108519

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1 citations

Victor Manuel Dzul-Huchim, Jonathan Mercado, Liliana Villanueva‐Lizama, María Elena Bottazzi, Kathryn M. Jones +3 more

Localized cardiac metabolic trajectories and post-infectious metabolic sequelae in experimental Chagas disease

Research Square(2023)10.21203/rs.3.rs-2497474/v1

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7 citations

Rebecca J. Ulrich, April Kendricks, Kate Wheeler, Ana Carolina Leão, Jeroen Pollet +6 more

The impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic Trypanosoma cruzi infection

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.11.548497

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0 citations

Cristina Poveda, Jeroen Pollet, Fabian Gusovsky, María Elena Bottazzi, Peter J. Hotez +2 more

Immunopeptidomic MHC-I profiling and immunogenicity testing identifies Tcj2 as a new Chagas disease mRNA vaccine candidate

PLoS Pathogens(2024)10.1371/journal.ppat.1012764

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11 citations

Rakesh Adhikari, Gonteria Robinson, Jungsoon Lee, Junfei Wei, Nelufa Islam +10 more

Parasitic Contamination of Soil in the Southern United States

American Journal of Tropical Medicine and Hygiene(2024)10.4269/ajtmh.24-0075

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21 citations

Sally Mingshuang Yan, David W. McCormick, Lauren Nicholas Herrera, Roumen Iordanov, Mark Daniel Bailey +4 more

The potential epidemiologic, clinical, and economic value of a universal coronavirus vaccine: a modelling study

EClinicalMedicine(2024)10.1016/j.eclinm.2023.102369

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20 citations

Kelly J. O’Shea, Danielle C. John, Ulrich Strych, María Elena Bottazzi, Marie F. Martinez +9 more

Vaccine value profile for schistosomiasis

Vaccine(2024)10.1016/j.vaccine.2024.05.068

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15 citations

Kaci Kennedy McDade, Roy M. Anderson, Sarah M. Bartsch, María Elena Bottazzi, David Diemert +13 more

What Is the Economic Benefit of Annual COVID-19 Vaccination From the Adult Individual Perspective?

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae179

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7 citations

Kelly J. O’Shea, Colleen Weatherwax, Ulrich Strych, Kavya Velmurugan, Danielle C. John +11 more

Optimization of Cellular Transduction by the HIV-Based Pseudovirus Platform with Pan-Coronavirus Spike Proteins

Viruses(2024)10.3390/v16091492

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3 citations

María José Villar, Jason T. Kimata, Ulrich Strych, María Elena Bottazzi, Peter J. Hotez +2 more

Mechanistic insights into structure-based design of a Lyme disease subunit vaccine

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.23.619738

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1 citations

Jill Malfetano, Ashley L. Marcinkiewicz, Alan Wang, Yilin Chen, Jungsoon Lee +9 more

Response to: “Quantifying the effect of vaccination on transmission in modelling studies”

EClinicalMedicine(2024)10.1016/j.eclinm.2024.102670

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0 citations

Kelly J. O’Shea, Ulrich Strych, María Elena Bottazzi, Bruce Y. Lee, Sarah M. Bartsch

The Current and Future Burden of Long COVID in the United States

The Journal of Infectious Diseases(2025)10.1093/infdis/jiaf030

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36 citations

Kevin L. Chin, Ulrich Strych, Danielle C. John, Tej Shah, María Elena Bottazzi +15 more

Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates

PLoS neglected tropical diseases(2025)10.1371/journal.pntd.0012809

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6 citations

Leroy Versteeg, Neima Briggs, Rakesh Adhikari, María José Villar, JeAnna R. Redd +4 more

Proteomic characterization and comparison of the infective and adult life stage secretomes from Necator americanus and Ancylostoma ceylanicum

PLoS neglected tropical diseases(2025)10.1371/journal.pntd.0012780

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6 citations

Bruce A. Rosa, Luke Becker, Mali Camberis, Graham Le Gros, Bin Zhan +12 more

Mechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine

Nature Communications(2025)10.1038/s41467-025-58182-x

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5 citations

Jill Malfetano, Ashley L. Marcinkiewicz, A. C. Wang, Yilin Chen, Jungsoon Lee +11 more

Different responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models

Frontiers in Immunology(2025)10.3389/fimmu.2025.1487317

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2 citations

María José Villar, Rakesh Adhikari, Cristina Poveda, Leroy Versteeg, Gregório Guilherme Almeida +4 more

Heterologous prime-pull mucosal vaccination with an adjuvanted RBD vaccine elicits robust IgA production and protects against SARS-CoV-2

Frontiers in Immunology(2025)10.3389/fimmu.2025.1673460

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1 citations

Calder Ellsworth, William Lewis, R. Craig, Amy E. Meyer, Jonatan Maldonado +11 more

Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention

American Journal of Preventive Medicine(2020)10.1016/j.amepre.2020.06.011

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364 citations

Kelly J. O’Shea, Marie C. Ferguson, María Elena Bottazzi, Patrick T. Wedlock, Ulrich Strych +6 more

Different pathways involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models 9260

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.2685

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0 citations

María José Villar, Rakesh Adhikari, Cristina Poveda, Leroy Versteeg, Gregório Guilherme Almeida +4 more