🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Jian‐Ke Tie

University of North Carolina at Chapel Hill

ORCID: 0000-0002-8447-3408
NursingPharmacology, Toxicology and PharmaceuticsMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

0in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 14 papers. Top paper: “A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle”.

A cell-based high-throughput screen identifies drugs that cause bleeding disorders by off-targeting the vitamin K cycle

Blood(2020)10.1182/blood.2019004234
N/A
0DataRank · unranked
12 citations

Caihong Li, Da‐Yun Jin, Brian O. Ingram, Zhenyu Hao, Xue Bai +4 more

Vitamin K epoxide reductase and its paralogous enzyme have different structures and functions

UNC Libraries(2020)10.17615/395r-b130
N/A
0DataRank · unranked
0 citations

Jian‐Ke Tie, Darrel W. Stafford, Balaji Chandra Sekhar Sinhadri, Da‐Yun Jin

Identification of the N-Linked Glycosylation Sites of Vitamin K-Dependent Carboxylase and Effect of Glycosylation on Carboxylase Function †

UNC Libraries(2020)10.17615/c585-qr41
N/A
0DataRank · unranked
0 citations

Mei-Yan Zheng, Jian‐Ke Tie, Darrel W. Stafford, R. Marshall Pope, David L. Straight

Transmembrane Domain Interactions and Residue Proline 378 Are Essential for Proper Structure, Especially Disulfide Bond Formation, in the Human Vitamin K-Dependent γ-Glutamyl Carboxylase †

UNC Libraries(2020)10.17615/ntqs-k459
N/A
0DataRank · unranked
0 citations

Kuang-Ling N. Hsiao, L. Perera, Darrel W. Stafford, Jian‐Ke Tie, David L. Straight +1 more

Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K‐dependent carboxylation

FEBS Journal(2021)10.1111/febs.16291
N/A
0DataRank · unranked
7 citations

Natsuko Furukawa, Da‐Yun Jin, Yizhou Liu, Darrel W. Stafford, Craig M. Williams +3 more

Evaluation of warfarin resistance using transcription activator-like effector nucleases-mediated vitamin K epoxide reductase knockout HEK293 cells

UNC Libraries(2021)10.17615/m14a-vw97
N/A
0DataRank · unranked
3 citations

Da-Yun Jin, Darrel W. Stafford, Jian‐Ke Tie, Kevin Tie

A genome-wide CRISPR-Cas9 knockout screen reveals FSP1 as warfarin-resistant vitamin K reductase

Research Square(2022)10.21203/rs.3.rs-2039668/v1
N/A
0DataRank · unranked
2 citations

Xuejie Chen, Yizhou Liu, Craig M. Williams, Lars C. Pedersen, Darrel W. Stafford +2 more

A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase

Nature Communications(2023)10.1038/s41467-023-36446-8
N/A
0DataRank · unranked
71 citations

Xuejie Chen, Yizhou Liu, Craig M. Williams, Lars C. Pedersen, Darrel W. Stafford +2 more

Molecular basis of inherited protein C deficiency results from genetic variations in the signal peptide and propeptide regions

Journal of Thrombosis and Haemostasis(2023)10.1016/j.jtha.2023.06.021
N/A
0DataRank · unranked
11 citations

Zhenyu Hao, Cheng Li, Xuejie Chen, Meng Gao, Nan Jiang +9 more

Small-molecule inhibition of γ-glutamyl carboxylase reveals a novel anticoagulant strategy

Blood Advances(2025)10.1182/bloodadvances.2025018776
N/A
0DataRank · unranked
2 citations

Dan Song, S Li, Xuejie Chen, Catherine E. Richter, Shixia Dong +9 more

In Silico and In Vitro Studies of Potential Novel Vitamin K Epoxide Reductase (VKOR) Inhibitors Suggest an Updated Structure–Activity Relationship

ACS Omega(2025)10.1021/acsomega.5c01116
N/A
0DataRank · unranked
1 citations

Stephani Joy Y. Macalino, Mengying Wang, Jian‐Ke Tie, Ser Loisse R. Mortel

Structural and functional insights into γ-glutamyl carboxylase-factor IX interaction: implications for vitamin K-dependent bleeding disorders

Haematologica(2025)10.3324/haematol.2025.287736
N/A
0DataRank · unranked
0 citations

Shixin Li, Guomin Shen, Jiangbo Tong, Nan Jiang, Minwen Hong +7 more

Molecular insights into the comorbidity of vitamin K-dependent clotting factor deficiency and chondrodysplasia punctata

Journal of Thrombosis and Haemostasis(2025)10.1016/j.jtha.2025.08.011
N/A
0DataRank · unranked
0 citations

Xuejie Chen, Mengying Wang, Xiaofeng Qi, Darrel W. Stafford, Sara Lewis +4 more

Selective targeting of coagulation factor X Gla domain by negatively charged gold nanoparticles: a novel method for controlled antithrombotic therapy

Materials Today Bio(2025)10.1016/j.mtbio.2025.102378
N/A
0DataRank · unranked
0 citations

Yuye Yin, Dongmei Hou, Yongchao Jin, Yuan Zhao, Jian Tong +11 more