Tomoyuki Mizuno

Cincinnati Children's Hospital Medical Center

Also affiliated with University of Cincinnati Medical Center

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 32 papers. Top paper: “A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1–associated pediatric low-grade glioma: a Neurofibromatosis Clinical Trials Consortium study”.

A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1–associated pediatric low-grade glioma: a Neurofibromatosis Clinical Trials Consortium study

Neuro-Oncology(2020)10.1093/neuonc/noaa071

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82 citations

Sanjay P. Prabhu, Alyssa Reddy, Michael J. Fisher, Roger J. Packer, Stewart Goldman +15 more

Real‐World Infliximab Pharmacokinetic Study Informs an Electronic Health Record‐Embedded Dashboard to Guide Precision Dosing in Children with Crohn’s Disease

Clinical Pharmacology & Therapeutics(2020)10.1002/cpt.2148

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72 citations

Tomoyuki Mizuno, Ruben J. Colman, Jeffrey S. Hyams, Joshua D. Noe, Brendan Boyle +9 more

Sirolimus Treatment in Sturge-Weber Syndrome

Pediatric Neurology(2020)10.1016/j.pediatrneurol.2020.10.013

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59 citations

Alyssa M. Day, Joshua B. Ewen, Jack H. Adamek, Anna W. Byars, Bernard A. Cohen +12 more

Physiologically‐Based Pharmacokinetic Modeling to Investigate the Effect of Maturation on Buprenorphine Pharmacokinetics in Newborns with Neonatal Opioid Withdrawal Syndrome

Clinical Pharmacology & Therapeutics(2021)10.1002/cpt.2458

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27 citations

Trevor N. Johnson, Brooks McPhail, Suyog Kamatkar, Scott L. Wexelblatt, Laura P. Ward +5 more

Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedolizumab clearance

Alimentary Pharmacology & Therapeutics(2022)10.1111/apt.17277

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24 citations

Tomoyuki Mizuno, Keizo Fukushima, David Haslam, Jeffrey S. Hyams, Brendan Boyle +10 more

Model-informed Precision Dosing for Biologics Is Now Available at the Bedside for Patients With Inflammatory Bowel Disease

Inflammatory Bowel Diseases(2022)10.1093/ibd/izac237

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17 citations

Abigail Samuels, Tomoyuki Mizuno, Nieko Punt, Alexander A. Vinks, Phillip Minar +1 more

Development and validation of a full physiologically-based pharmacokinetic model for sublingual buprenorphine that accounts for nonlinear bioavailability

(2022)10.22541/au.165479409.90378585/v1

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1 citations

Trevor N. Johnson, Alexander A. Vinks, Tomoyuki Mizuno, Matthijs W. van Hoogdalem

Development and validation of a full physiologically-based pharmacokinetic model for sublingual buprenorphine that accounts for nonlinear bioavailability

(2022)10.22541/au.165479409.90378585/v2

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0 citations

Trevor N. Johnson, Alexander A. Vinks, Tomoyuki Mizuno, Matthijs W. van Hoogdalem

Artificial Intelligence and Machine Learning Approaches to Facilitate Therapeutic Drug Management and Model-Informed Precision Dosing

Therapeutic Drug Monitoring(2023)10.1097/ftd.0000000000001078

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128 citations

Alexander A. Vinks, Tomoyuki Mizuno, Ethan A. Poweleit

Tutorial on model selection and validation of model input into precision dosing software for model‐informed precision dosing

CPT Pharmacometrics & Systems Pharmacology(2023)10.1002/psp4.13056

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34 citations

Ethan A. Poweleit, Kelli Paice, Katherine Somers, Kathryn Pavia, Alexander A. Vinks +4 more

Escitalopram and Sertraline Population Pharmacokinetic Analysis in Pediatric Patients

Clinical Pharmacokinetics(2023)10.1007/s40262-023-01294-8

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25 citations

Zachary L. Taylor, Tomoyuki Mizuno, Samuel Vaughn, Zeruesenay Desta, Jeffrey R. Strawn +2 more

Rationale, Development, and Validation of HdxSim, a Clinical Decision Support Tool for Model‐Informed Precision Dosing of Hydroxyurea for Children with Sickle Cell Anemia

Clinical Pharmacology & Therapeutics(2023)10.1002/cpt.3119

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9 citations

Min Dong, Nieko Punt, Tomoyuki Mizuno, Luke R. Smart, Alexander A. Vinks +2 more

Cefepime pharmacokinetics in critically ill children and young adults undergoing continuous kidney replacement therapy

Journal of Antimicrobial Chemotherapy(2023)10.1093/jac/dkad192

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7 citations

H. Rhodes Hambrick, Kelli Paice, Peter Tang, Nieko Punt, Jennifer Kaplan +5 more

Ceftriaxone Pharmacokinetics and Pharmacodynamics in 2 Pediatric Patients on Extracorporeal Membrane Oxygenation Therapy

Therapeutic Drug Monitoring(2023)10.1097/ftd.0000000000001133

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1 citations

Tomoyuki Mizuno, Min Dong, Peter Tang, Trent Arbough, Alexander A. Vinks +3 more

Preventative treatment of tuberous sclerosis complex with sirolimus: Phase I safety and efficacy results

Annals of the Child Neurology Society(2024)10.1002/cns3.20070

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17 citations

David M. Ritter, David Neal Franz, Molly S. Griffith, Kristn Currans, Bridget Kent +15 more

Acute kidney injury is associated with abnormal cefepime exposure among critically ill children and young adults

Pediatric Nephrology(2024)10.1007/s00467-024-06477-4

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10 citations

Sonya Tang Girdwood, Kelli Paice, Min Dong, Tomoyuki Mizuno, Peter Tang +4 more

Pharmacokinetic Factors Associated With Early Meropenem Target Attainment in Pediatric Severe Sepsis*

Pediatric Critical Care Medicine(2024)10.1097/pcc.0000000000003599

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10 citations

Sonya Tang Girdwood, Tomoyuki Mizuno, Kathryn Pavia, Nieko Punt, Peter Tang +7 more

Identifying optimal dosing strategies for meropenem in the paediatric intensive care unit through modelling and simulation

Journal of Antimicrobial Chemotherapy(2024)10.1093/jac/dkae274

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9 citations

Tomoyuki Mizuno, Kelli Paice, Kathryn Pavia, H. Rhodes Hambrick, Peter Tang +7 more

Cystatin C Outperforms Creatinine in Predicting Cefepime Clearance in Pediatric Stem Cell Transplant Recipients

Transplantation and Cellular Therapy(2024)10.1016/j.jtct.2024.03.021

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7 citations

Lin Fei, Kathryn Pavia, Jennifer Kaplan, Tomoyuki Mizuno, Peter Tang +4 more

Impact of fluid balance on beta-lactam antibiotics target attainment: Insights from a simulation-based meropenem study

International Journal of Antimicrobial Agents(2024)10.1016/j.ijantimicag.2024.107267

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8 citations

Tomoyuki Mizuno, Kelli Paice, H. Rhodes Hambrick, Nieko Punt, Sonya Tang Girdwood +1 more

Development and Verification of a Full Physiologically Based Pharmacokinetic Model for Sublingual Buprenorphine in Healthy Adult Volunteers that Accounts for Nonlinear Bioavailability

Drug Metabolism and Disposition(2024)10.1124/dmd.124.001643

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5 citations

Ryota Tanaka, Trevor N. Johnson, Alexander A. Vinks, Tomoyuki Mizuno, Matthijs W. van Hoogdalem

Monte Carlo simulations of cefepime in children receiving continuous kidney replacement therapy support continuous infusions for target attainment

Journal of Intensive Care(2024)10.1186/s40560-024-00752-0

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4 citations

Nieko Punt, Kathryn Pavia, Tomoyuki Mizuno, Stuart L. Goldstein, Sonya Tang Girdwood +1 more

Preventative treatment of tuberous sclerosis complex with sirolimus: Phase I safety and efficacy results

UNC Libraries(2024)10.17615/f64k-h824

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0 citations

David Neal Franz, Kenneth D.R. Setchell, Kristn Currans, Bridget Kent, E. Martina Bebin +15 more

Integrating early response biomarkers in pharmacokinetic models: A novel method to individualize the initial infliximab dose in patients with Crohn's disease

Clinical and Translational Science(2025)10.1111/cts.70086

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6 citations

Kei Irie, Tomoyuki Mizuno, Jack Reifenberg, Nieko Punt, Alexander A. Vinks +2 more

Hybrid Population Pharmacokinetic–Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn’s Disease

Clinical Pharmacokinetics(2025)10.1007/s40262-025-01564-7

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6 citations

Phillip Minar, Jack Reifenberg, Brendan M. Boyle, Joshua D. Noe, Jeffrey S. Hyams +2 more

Population Pharmacokinetics of Cefepime in Critically Ill Children and Young Adults: Model Development and External Validation for Monte Carlo Simulations and Model-Informed Precision Dosing

Clinical Pharmacokinetics(2025)10.1007/s40262-025-01485-5

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5 citations

H. Rhodes Hambrick, Tomoyuki Mizuno, Kathryn Pavia, Kelli Paice, Peter Torben Tang +10 more

Model‐Informed Deep Q‐Networks to Guide Infliximab Dosing in Pediatric Crohn’s Disease

Clinical Pharmacology & Therapeutics(2025)10.1002/cpt.70118

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2 citations

Phillip Minar, Jack Reifenberg, Brendan M. Boyle, Joshua D. Noe, Jeffrey S. Hyams +2 more

Model-informed dose optimization for prophylactic piperacillin-tazobactam in perioperative pediatric critically ill patients

Antimicrobial Agents and Chemotherapy(2025)10.1128/aac.01227-24

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2 citations

Kei Irie, Carter McIntire, Julie Luna Torres, Rhonda Jones, Abigayle Gibson +3 more

From PICU to NICU: Extrapolating Meropenem Exposure From Pediatric to Neonatal Intensive Care Patients

The Journal of Clinical Pharmacology(2025)10.1002/jcph.70097

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2 citations

Tomoyuki Mizuno, Wen Rui Tan, Kei Irie, Sonya Tang Girdwood, Ronaldo Morales

IMPDH and GTP Metabolism in Cancer: Mechanisms, Regulation, and Translational Scope

Cancer Science(2025)10.1111/cas.70200

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1 citations

Koh Takeuchi, Keita Shigemi, Michelle Jane Genoveso, Hiroaki Niitsu, Iemasa Koh +16 more

Hybrid Population PK-Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.01.651780

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0 citations

Phillip Minar, Jack Reifenberg, Brendan M. Boyle, Joshua D. Noe, Jeffrey S. Hyams +2 more

Model-informed Deep Q-Networks to Guide Infliximab Dosing in Pediatric Crohn’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.14.664804

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0 citations

Phillip Minar, Jack Reifenberg, Brendan M. Boyle, Joshua D. Noe, S Jeffrey Hyams +2 more