Ling Cai

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.466Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Lung Cancer Computational Biology and Resources

Cold Spring Harbor Perspectives in Medicine(2021)10.1101/cshperspect.a038273

Top 41%

0.466DataRank

Top 41%9 citations

Guanghua Xiao, David E. Gerber, John D. Minna, Yang Xie, Ling Cai

Papers

Driven by 43 papers — median percentile 59. Top paper: “DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation”.

DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation

Nature Communications(2021)10.1038/s41467-021-22665-4

N/A

0.722DataRank · unranked

122 citations

Huitao Fan, Sara A. Grimm, Jae Jin Kim, Linhui Li, Yiran Guo +21 more

Lung Cancer Computational Biology and Resources

Cold Spring Harbor Perspectives in Medicine(2021)10.1101/cshperspect.a038273

Top 41%

0.466DataRank

Top 41%9 citations

Guanghua Xiao, David E. Gerber, John D. Minna, Yang Xie, Ling Cai

Assessing consistency across functional screening datasets in cancer cells

Bioinformatics(2021)10.1093/bioinformatics/btab423

N/A

0.336DataRank · unranked

7 citations

Hongyu Liu, John D. Minna, Ralph J. DeBerardinis, Guanghua Xiao, Yang Xie +1 more

The sotos syndrome gene Nsd1 safeguards developmental gene enhancers poised for transcription by maintaining the precise deposition of histone methylation

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108423

N/A

0.176DataRank · unranked

2 citations

Zhucui Li, Jiekai Yin, Yinsheng Wang, Deyou Zheng, Ling Cai +2 more

Dissecting molecular, pathological, and clinical features associated with tumor neural/neuroendocrine heterogeneity

iScience(2023)10.1016/j.isci.2023.106983

N/A

0.118DataRank · unranked

1 citations

Ralph J. DeBerardinis, Guanghua Xiao, John D. Minna, Yang Xie, Ling Cai

YY1 cistrome analysis uncovers an essential requirement of the YY1:BRD4-PFKP regulatory axis for promoting tumorigenesis of castration-resistant prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.17.302596

N/A

0DataRank · unranked

0 citations

Yi‐Hsuan Tsai, Phillip M. Galbo, Weida Gong, Aaron J. Storey, Yuemei Xu +12 more

Phase separation drives aberrant chromatin looping and cancer development

Nature(2021)10.1038/s41586-021-03662-5

N/A

0DataRank · unranked

470 citations

Eric S. Davis, Timothy A. Daugird, Shuai Zhao, Ivana Yoseli Quiroga, Hidetaka Uryu +14 more

A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models

Science Translational Medicine(2021)10.1126/scitranslmed.abj1578

N/A

0DataRank · unranked

158 citations

Dongxu Li, Jithesh Kottur, Yudao Shen, Huen Suk Kim, Kwang‐Su Park +14 more

Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer

Communications Biology(2021)10.1038/s42003-021-01842-7

N/A

0DataRank · unranked

101 citations

Hongyu Liu, Fang Huang, Junya Fujimoto, Luc Girard, Jun Chen +25 more

A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells

Cell chemical biology(2021)10.1016/j.chembiol.2021.08.004

N/A

0DataRank · unranked

62 citations

Fanye Meng, Kwang‐Su Park, Aaron J. Storey, Weida Gong, Yi‐Hsuan Tsai +12 more

Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer

Nucleic Acids Research(2021)10.1093/nar/gkab252

N/A

0DataRank · unranked

53 citations

Yi‐Hsuan Tsai, Phillip M. Galbo, Weida Gong, Aaron J. Storey, Yuemei Xu +13 more

ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism

Nature Communications(2021)10.1038/s41467-021-21357-3

N/A

0DataRank · unranked

42 citations

Phillip M. Galbo, Weida Gong, Aaron J. Storey, Yi‐Hsuan Tsai, Xufen Yu +13 more

A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing

Nucleic Acids Research(2021)10.1093/nar/gkab210

N/A

0DataRank · unranked

30 citations

Yiran Guo, Yi‐Hsuan Tsai, Aaron J. Storey, Arum Kim, Weida Gong +8 more

EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis

Nature Cell Biology(2022)10.1038/s41556-022-00850-x

N/A

0DataRank · unranked

184 citations

Xufen Yu, Weida Gong, Xijuan Liu, Kwang‐Su Park, Anqi Ma +12 more

Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic

Oncogene(2022)10.1038/s41388-022-02340-8

N/A

0DataRank · unranked

56 citations

Xufen Yu, Jithesh Kottur, Weida Gong, Zhao Zhang, Aaron J. Storey +14 more

Tumor Cells Modulate Macrophage Phenotype in a Novel In Vitro Co-Culture Model of the NSCLC Tumor Microenvironment

Journal of Thoracic Oncology(2022)10.1016/j.jtho.2022.06.011

N/A

0DataRank · unranked

53 citations

Raghav Chandra, Ling Cai, Debolina Ganguly, Huiyu Li, Jason E. Toombs +4 more

A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant, promoting oncogene activation and tumorous transformation

Nucleic Acids Research(2022)10.1093/nar/gkac861

N/A

0DataRank · unranked

41 citations

Kwang‐Su Park, Xufen Yu, Weida Gong, H. Shelton Earp, Gang Greg Wang +3 more

A Pan-Cancer Assessment of RB1/TP53 Co-Mutations

Cancers(2022)10.3390/cancers14174199

N/A

0DataRank · unranked

18 citations

Ralph J. DeBerardinis, Guanghua Xiao, John D. Minna, Yang Xie, Ling Cai

A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant promoting oncogene activation and tumorous transformation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.04.502794

N/A

0DataRank · unranked

5 citations

Kwang‐Su Park, Xufen Yu, Weida Gong, H. Shelton Earp, Gang Greg Wang +3 more

A comparative study of neuroendocrine heterogeneity in SCLC and NBL

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.17.516959

N/A

0DataRank · unranked

1 citations

Ralph J. DeBerardinis, Yang Xie, John D. Minna, Guanghua Xiao, Ling Cai

TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons

Nature(2023)10.1038/s41586-023-06688-z

N/A

0DataRank · unranked

69 citations

Jiuwei Lu, Bo Pan, Huitao Fan, Stephanie D. Byrum, Chenxi Xu +18 more

Molecular and Pathologic Characterization of YAP1-Expressing Small Cell Lung Cancer Cell Lines Leads to Reclassification as SMARCA4-Deficient Malignancies

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-2360

N/A

0DataRank · unranked

67 citations

Ling Cai, Luc Girard, Owen W.J. Prall, Neeha Rajan, Christine Khoo +9 more

Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01521

N/A

0DataRank · unranked

51 citations

Dongxu Li, Jithesh Kottur, Huen Suk Kim, Laura E. Herring, Yao Yu +9 more

Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader

Oncogene(2023)10.1038/s41388-023-02618-5

N/A

0DataRank · unranked

26 citations

Jun Wang, Weida Gong, Anqi Ma, Yudao Shen, Chengwei Zhang +6 more

Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer

Journal of Clinical Investigation(2023)10.1172/jci160330

N/A

0DataRank · unranked

21 citations

Ruichen Rong, Donghan M. Yang, Junya Fujimoto, Justin A. Bishop, Shirley Yan +15 more

Epigenetic (De)regulation in Prostate Cancer

Cancer treatment and research(2023)10.1007/978-3-031-45654-1_10

N/A

0DataRank · unranked

2 citations

Shuai Zhao, Ling Cai, Chenxi Xu

Mitochondrial complex I promotes kidney cancer metastasis

Nature(2024)10.1038/s41586-024-07812-3

N/A

0DataRank · unranked

117 citations

Luigi Perelli, Nicholas P. Lesner, Ling Cai, Bailey Brooks, Zheng Wu +33 more

Electron transport chain inhibition increases cellular dependence on purine transport and salvage

Cell Metabolism(2024)10.1016/j.cmet.2024.05.014

N/A

0DataRank · unranked

91 citations

Divya Bezwada, Feng Cai, Robert C. Harris, Bookyung Ko, Varun Sondhi +21 more

Concurrent loss of LKB1 and KEAP1 enhances SHMT-mediated antioxidant defence in KRAS-mutant lung cancer

Nature Metabolism(2024)10.1038/s42255-024-01066-z

N/A

0DataRank · unranked

25 citations

Nefertiti Muhammad, Elizabeth L. Lieu, Feng Cai, Jiawei Mu, Yun‐Sok Ha +18 more

Navigating electronic health record accuracy by examination of sex incongruent conditions

Journal of the American Medical Informatics Association(2024)10.1093/jamia/ocae236

N/A

0DataRank · unranked

8 citations

Ralph J. DeBerardinis, Xiaowei Zhan, Guanghua Xiao, Yang Xie, Ling Cai

Glycosaminoglycan-mediated lipoprotein uptake protects cancer cells from ferroptosis

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.13.593939

N/A

0DataRank · unranked

2 citations

Lingjie Sang, Divya Bezwada, Nathaniel Kim, Amrita Basu, Sheng‐Chieh Hsu +15 more

TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons

UNC Libraries(2024)10.17615/cd08-n795

N/A

0DataRank · unranked

0 citations

Arum Kim, Nathaniel T. Burkholder, Krishna Kanchi, Yiran Guo, Jikui Song +18 more

High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non–Small Cell Lung Cancer in Patients

Cancer Discovery(2025)10.1158/2159-8290.cd-23-1319

N/A

0DataRank · unranked

16 citations

Nia G. Hammond, Alpaslan Tasdogan, Massar Alsamraae, Chendong Yang, Robert B. Cameron +40 more

Conservation and divergence of metabolic phenotypes between patient tumours and matched xenografts

Nature Metabolism(2025)10.1038/s42255-025-01338-2

N/A

0DataRank · unranked

3 citations

Ling Cai, Marelize Snyman, Rachel Elizabeth Walsdorf, Xiangyi Li, Sophia Wix +20 more

BAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication

Nature Communications(2025)10.1038/s41467-025-61284-1

N/A

0DataRank · unranked

3 citations

Zhimin Zhang, Mei Liu, Yu Yao, Yiran Guo, Samuel G. Mackintosh +12 more

Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300

Biochemical Journal(2025)10.1042/bcj20253037

N/A

0DataRank · unranked

1 citations

Soumi Biswas, Chenxi Xu, Hongwen Xuan, Moustafa Khalil, Ling Cai +7 more

L-2-hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.16.649033

N/A

0DataRank · unranked

0 citations

Xun Wang, Ashley Solmonson, Ling Cai, Yi Xiao, Alpaslan Tasdogan +18 more

Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2009316117

N/A

0DataRank · unranked

116 citations

Huitao Fan, Sara A. Grimm, Yiran Guo, Jae Jin Kim, Jiekai Yin +20 more

YY1 relieves p300 autoinhibition to promote histone acetylation in advanced prostate cancer, enhancing the oncogenic signaling of Androgen Receptor Splice Variant 7

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.04.668477

N/A

0DataRank · unranked

0 citations

Dongyu Wu, Bo Pan, Xiaoxiao Ren, Samuel G. Mackintosh, Kanishk Jain +9 more

Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer

Journal of Clinical Investigation(2020)10.1172/jci139929

N/A

0DataRank · unranked

76 citations

Kenneth E. Huffman, Zixi Wang, Xun Wang, Kailong Li, Feng Cai +23 more

Molecular differences across invasive lung adenocarcinoma morphological subgroups

Translational Lung Cancer Research(2020)10.21037/tlcr-19-321

N/A

0DataRank · unranked

22 citations

Donghan M. Yang, Ling Cai, Lin Yang, Luc Girard, Junya Fujimoto +6 more

Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion

Nature Communications(2020)10.1038/s41467-020-17098-4

N/A

0DataRank · unranked

27 citations

Yiran Guo, Sheryl M. Gough, Jinyong Zhang, Kendra R. Vann, Kuai Li +6 more

Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.27.064493

N/A

0DataRank · unranked

11 citations

Huitao Fan, Sara A. Grimm, Yiran Guo, Jae Jin Kim, Linhui Li +20 more

Ling Cai

Indexed papers

Top data-sharing exemplar

Papers