🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Kai Trepka

University of California, San Francisco

ORCID: 0000-0002-8672-6317

Also affiliated with UCSF Benioff Children's Hospital, University of San Francisco

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile
1.3Author DataRank

Indexed papers

2in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta

PLoS Biology(2023)10.1371/journal.pbio.3002125
Top 19%
1.1DataRank
Top 19%42 citations

Juan M. Sánchez, Jordan E. Bisanz, Veronica Escalante, Margaret Alexander, Kai Trepka +7 more

Papers

Driven by 18 papers — median percentile 59. Top paper: “Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta”.

Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta

PLoS Biology(2023)10.1371/journal.pbio.3002125
Top 19%
1.1DataRank
Top 19%42 citations

Juan M. Sánchez, Jordan E. Bisanz, Veronica Escalante, Margaret Alexander, Kai Trepka +7 more

A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity

Cell Reports(2024)10.1016/j.celrep.2024.114891
N/A
0.926DataRank · unranked
29 citations

Vaibhav Upadhyay, Rachel Rock, Lorenzo Ramirez, Kai Trepka, Patrycja Puchalska +12 more

Theranostic Targeting of CUB Domain–Containing Protein 1 (CDCP1) in Multiple Subtypes of Bladder Cancer

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-22-1973
N/A
0.553DataRank · unranked
11 citations

Kai Trepka, Sasank Sakhamuri, Alberto Carretero-González, Jun Zhu, Emily A. Egusa +9 more

Systems biology illuminates alternative metabolic niches in the human gut microbiome

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.19.508335
Top 63%
0.218DataRank
Top 63%3 citations

Juan M. Sánchez, Jordan E. Bisanz, Veronica Escalante, Margaret Alexander, Kai Trepka +7 more

Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.13.512142
N/A
0DataRank · unranked
1 citations

Moriah Sandy, Kai Trepka, Janice JN Goh, Kristie B. Yu, Vincent DiMassa +4 more

Associations between the Gut Microbiota, Race, and Ethnicity of Patients with Colorectal Cancer: A Pilot and Feasibility Study

Cancers(2023)10.3390/cancers15184546
N/A
0DataRank · unranked
18 citations

Than S. Kyaw, Kai Trepka, Anita L. Stewart, Rosa Mora, Dalila Stanfield +7 more

A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.02.565382
N/A
0DataRank · unranked
8 citations

Vaibhav Upadhyay, Rachel Rock, Lorenzo Ramirez, Kai Trepka, Patrycja Puchalska +12 more

Pharma[e]cology: How the Gut Microbiome Contributes to Variations in Drug Response

The Annual Review of Pharmacology and Toxicology(2024)10.1146/annurev-pharmtox-022724-100847
N/A
0DataRank · unranked
19 citations

C. Anders Olson, Vaibhav Upadhyay, Chen Zhang, Peter J. Turnbaugh, Kai Trepka

Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors

iScience(2024)10.1016/j.isci.2024.110122
N/A
0DataRank · unranked
14 citations

Chen Zhang, Moriah Sandy, Kai Trepka, Shenwei Zhang, Luis A. Ramirez Hernandez +10 more

Metagenomic analysis during capecitabine therapy reveals microbial chemoprotective mechanisms and predicts drug toxicity in colorectal cancer patients

medRxiv(2024)10.1101/2024.10.11.24315249
N/A
0DataRank · unranked
1 citations

Kai Trepka, Janine Ziemons, Romy Aarnoutse, Benjamin G. H. Guthrie, Judith de Vos‐Geelen +11 more

Pragmatic Emergency Department Intervention Reducing Default Quantity of Opioid Tablets Prescribed

Western Journal of Emergency Medicine(2024)10.5811/westjem.18040
N/A
0DataRank · unranked
0 citations

Alice Y. Lu, Georgia A. Kirn, Kai Trepka, Yesenia Ayana Day, Stephen C. Yang +3 more

Expansion of a bacterial operon during cancer treatment ameliorates fluoropyrimidine toxicity

Science Translational Medicine(2025)10.1126/scitranslmed.adq8870
N/A
0DataRank · unranked
13 citations

Wesley A. Kidder, Than S. Kyaw, Taylor M. Halsey, C. Anders Olson, Edwin F. Ortega +14 more

Comprehensive Cross-Domain Taxonomic Classification of Microbiotas using Partitioned Amplification Multiplexed Amplicon Sequencing (PAMA-seq)

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.18.660470
N/A
0DataRank · unranked
0 citations

Kai Trepka, Fangchao Song, Than S. Kyaw, Peter J. Turnbaugh, Adam R. Abate +1 more

CUB domain containing protein 1 (CDPC1) is a target for radioligand therapy in castration resistant prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.17.448569
N/A
0DataRank · unranked
0 citations

Kai Trepka, Yung-Hua Wang, Shalini Chopra, Nima Hooshdaran, Hyun‐Jung Kim +14 more

Shifts in the human gut microbiome during cancer chemotherapy are diet-dependent

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.23.696294
N/A
0DataRank · unranked
0 citations

Erin L. Van Blarigan, Than S Kyaw, C. Anders Olson, Gina Partipilo, Edwin F. Ortega +11 more

TROP2 Expression Across Molecular Subtypes of Urothelial Carcinoma and Enfortumab Vedotin-resistant Cells

European Urology Oncology(2022)10.1016/j.euo.2021.11.005
N/A
0DataRank · unranked
87 citations

Kai Trepka, Martin Sjöström, Emily A. Egusa, Carissa Chu, Jun Zhu +14 more

Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer

Cancer Research(2022)10.1158/0008-5472.can-22-1433
N/A
0DataRank · unranked
61 citations

Emily A. Egusa, Sinan Wang, Michelle L. Badura, Fei Lee, Anil P. Bidkar +22 more

CUB Domain-Containing Protein 1 (CDCP1) Is a Target for Radioligand Therapy in Castration-Resistant Prostate Cancer, including PSMA Null Disease

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-21-3858
N/A
0DataRank · unranked
30 citations

Shalini Chopra, Kai Trepka, Yung-Hua Wang, Sasank Sakhamuri, Nima Hooshdaran +18 more