Coen A. C. Ottenheijm

Also affiliated with Amsterdam Neuroscience, Amsterdam University Medical Centers, Amsterdam University of Applied Sciences, Amsterdam UMC Location Vrije Universiteit Amsterdam

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 21 papers. Top paper: “Preserved single muscle fiber specific force in facioscapulohumeral muscular dystrophy”.

Preserved single muscle fiber specific force in facioscapulohumeral muscular dystrophy

Neurology(2020)10.1212/wnl.0000000000008977

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12 citations

Nicol C. Voermans, Robbert van der Pijl, Marloes van den Berg, Arend Heerschap, Hieronymus Van Hees +5 more

Deleting Titin’s C-Terminal PEVK Exons Increases Passive Stiffness, Alters Splicing, and Induces Cross-Sectional and Longitudinal Hypertrophy in Skeletal Muscle

Frontiers in Physiology(2020)10.3389/fphys.2020.00494

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17 citations

Brian Hudson, Tomotaroh Granzier-Nakajima, Frank Li, J. André Knottnerus, John E. Smith +5 more

Muscle ankyrin repeat protein 1 (MARP1) locks titin to the sarcomeric thin filament and is a passive force regulator

The Journal of General Physiology(2021)10.1085/jgp.202112925

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35 citations

Marloes van den Berg, Martijn van de Locht, Shengyi Shen, Sylvia J. P. Bogaards, Stefan Conijn +7 more

The titin N2B and N2A regions: biomechanical and metabolic signaling hubs in cross-striated muscles

Biophysical Reviews(2021)10.1007/s12551-021-00836-3

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32 citations

Andrea A. Domenighetti, Farah Sheikh, Elisabeth Ehler, Coen A. C. Ottenheijm, Stephan Lange +1 more

Pathogenic variants in TNNC2 cause congenital myopathy due to an impaired force response to calcium

Journal of Clinical Investigation(2021)10.1172/jci145700

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24 citations

Sandra Donkervoort, Josine M. de Winter, Stefan Conijn, Leon P. L. Begthel, Benno Küsters +20 more

Acute and chronic tirasemtiv treatment improves in vivo and in vitro muscle performance in actin-based nemaline myopathy mice

Human Molecular Genetics(2021)10.1093/hmg/ddab112

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18 citations

Charlotte Gineste, Elisa Minardi, Lorenza Brocca, Maira Rossi, Tamara C. Borsboom +10 more

COVID-19 is associated with distinct myopathic features in the diaphragm of critically ill patients

BMJ Open Respiratory Research(2021)10.1136/bmjresp-2021-001052

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13 citations

Sylvia J. P. Bogaards, Stefan Conijn, Y. L. Onderwater, Pedro Espinosa, Diewertje I. Bink +8 more

Skeletal myopathy in a rat model of postmenopausal heart failure with preserved ejection fraction

Journal of Applied Physiology(2021)10.1152/japplphysiol.00170.2021

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10 citations

Lauren Gabriel Betancourt, Andrea M. Noriega, Suzanne C. Brinson, Nuria Curbelo-Bermudez, Dongwoo Hahn +9 more

Titin–N2A: More than a signaling node?

The Journal of General Physiology(2021)10.1085/jgp.202112904

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3 citations

Coen A. C. Ottenheijm, Robbert van der Pijl

Assessment of PABPN1 nuclear inclusions on a large cohort of patients and in a human xenograft model of oculopharyngeal muscular dystrophy

Acta Neuropathologica(2022)10.1007/s00401-022-02503-7

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16 citations

Jamila Dhiab, Alexis Boulinguiez, Hadidja‐Rose Mouigni, Saskia Lassche, Elisa Négroni +16 more

Rbm20ΔRRM Mice, Expressing a Titin Isoform with Lower Stiffness, Are Protected from Mechanical Ventilation-Induced Diaphragm Weakness

International Journal of Molecular Sciences(2022)10.3390/ijms232415689

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9 citations

Eva L. Peters, Robbert van der Pijl, Shengyi Shen, Leo Heunks, Henk Granzier +2 more

Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2221244120

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27 citations

Weikang Ma, Taejeong Song, Hosna Rastegarpouyani, Henry Gong, Isabella Leite Coscarella +12 more

Super relaxed myosins loosen up to different cues in cardiac and skeletal muscle sarcomeres

The Journal of General Physiology(2023)10.1085/jgp.202213292

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1 citations

Coen A. C. Ottenheijm, Wout J. Claassen

Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients

Science Translational Medicine(2024)10.1126/scitranslmed.adg3894

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28 citations

Zhonghua Shi, Wout J. Claassen, Pleuni E. Hooijman, Christopher T. A. Lewis, Jesper L. Andersen +23 more

Comprehensive phenotypic characterization of an allelic series of zebrafish models of NEB-related nemaline myopathy

Human Molecular Genetics(2024)10.1093/hmg/ddae033

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5 citations

Esmat Karimi, Gerrie P. Farman, Jochen Gohlke, Coen A. C. Ottenheijm, Hendrikus L Granzier +2 more

Generation of a novel mouse model of nemaline myopathy due to recurrent NEB exon 55 deletion

Research Square(2024)10.21203/rs.3.rs-5456324/v1

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0 citations

Justin Kolb, Nesrin Sabha, Esmat Karimi, Zaynab Hourani, Coen A. C. Ottenheijm +3 more

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Journal of Visualized Experiments(2025)10.3791/67474

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1 citations

Wout J. Claassen, Nick van Huis, Ruslan Garipov, Lindy K. Alles, Leo Heunks +4 more

Embedding muscle fibers in hydrogel improves viability and preserves contractile function during prolonged ex vivo culture

The Journal of General Physiology(2025)10.1085/jgp.202513761

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1 citations

Özlem Esen, Daan Hoomoedt, Rajvi M.N. Balesar, Coen A. C. Ottenheijm, Tyler J. Kirby +1 more

Intraoperative phrenic nerve stimulation to prevent diaphragm fiber weakness during thoracic surgery

PLoS ONE(2025)10.1371/journal.pone.0320936

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1 citations

Thomas M. Beaver, A. Daniel Martin, Robbert van der Pijl, Robert T. Mankowski, Christiaan Leeuwenburgh +9 more

The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch

eLife(2025)10.1101/2025.06.19.660595

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1 citations

Jochen Gohlke, Joshua Strom, Eva L. Peters, Shengyi Shen, Stefan Conijn +8 more

Embedding muscle fibers in hydrogel improves viability and preserves contractile function during prolonged ex vivo culture

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.13.632729

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0 citations

Özlem Esen, Daan Hoomoedt, Rajvi M.N. Balesar, Coen A. C. Ottenheijm, Tyler J. Kirby +1 more