Jack A. Roth

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.332Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis

Cancer Research(2024)10.1158/0008-5472.can-23-1349

Top 62%

0.222DataRank

Top 62%3 citations

Xing Yi Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang +49 more

Papers

Driven by 33 papers — median percentile 28. Top paper: “Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery”.

Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery

The Lancet Oncology(2021)10.1016/s1470-2045(21)00401-0

N/A

6.1DataRank · unranked

319 citations

Reza J. Mehran, Lei Feng, Vivek Verma, Zhongxing Liao, James W. Welsh +30 more

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Nature Genetics(2021)10.1038/s41588-020-00750-6

N/A

0.790DataRank · unranked

193 citations

Jessica Giordano, Anuj Srivastava, Min Jin Ha, Michael W. Lloyd, Roebi de Bruijn +57 more

CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Nature(2024)10.1038/s41586-024-07943-7

N/A

0.769DataRank · unranked

168 citations

Haniel A. Araújo, Minh Truong, Yu Qian, Xin Sun, Ana Galán‐Cobo +95 more

Genotype-Specific Differences in Circulating Tumor DNA Levels in Advanced NSCLC

Journal of Thoracic Oncology(2020)10.1016/j.jtho.2020.12.011

N/A

0.678DataRank · unranked

91 citations

Jianjun Zhang, Carol C. Wu, Hai T. Tran, Lerong Li, Lixia Diao +13 more

3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib

Communications Biology(2023)10.1038/s42003-023-04889-w

N/A

0.373DataRank · unranked

11 citations

Mourad Majidi, Bingliang Fang, Feng Meng, Lihui Gao, Ruping Shao +16 more

A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis

Cancer Research(2024)10.1158/0008-5472.can-23-1349

Top 62%

0.222DataRank

Top 62%3 citations

Xing Yi Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang +49 more

PDXNet Portal: Patient-Derived Xenograft model, data, workflow, and tool discovery

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.15.464537

Top 72%

0.110DataRank

Top 72%1 citations

Michael W. Lloyd, Jeffrey Grover, Sara Seepo, Sai Lakshmi Subramanian, Manisha Ray +34 more

Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

Cancer Cell(2021)10.1016/j.ccell.2020.12.014

N/A

0DataRank · unranked

945 citations

C. Allison Stewart, Elizabeth M. Park, Lixia Diao, Sarah M. Groves, Simon Heeke +25 more

Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2021-002891

N/A

0DataRank · unranked

292 citations

Ferdinandos Skoulidis, Meagan Montesion, Katja Schulze, Ilze Bāra, Vincent K. Shen +33 more

Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer

Annals of Oncology(2021)10.1016/j.annonc.2021.09.021

N/A

0DataRank · unranked

137 citations

Daniel J. McGrail, Salah-Eddine Bentebibel, Cara Haymaker, Angelo Ravelli, Marie‐Andrée Forget +31 more

Preoperative Maximum Standardized Uptake Value Associated With Recurrence Risk in Early Lung Cancer

The Annals of Thoracic Surgery(2021)10.1016/j.athoracsur.2021.06.017

N/A

0DataRank · unranked

15 citations

Wayne L. Hofstetter, Reza J. Mehran, Ravi Rajaram, David C. Rice, Jack A. Roth +7 more

Epstein Barr virus–positive B-cell lymphoma is highly vulnerable to MDM2 inhibitors in vivo

Blood Advances(2021)10.1182/bloodadvances.2021006156

N/A

0DataRank · unranked

8 citations

Ran Zhang, Chenghui Ren, Yi Xu, Shuhong Wu, Carrie Meng +19 more

A focal adhesion kinase-YAP signaling axis drives drug tolerant persister cells and residual disease in lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.23.465573

N/A

0DataRank · unranked

18 citations

Celia Fernández-Méndez, Lauren Čech, Johnny Yu, Ismail M. Meraz, Victor Olivas +28 more

CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.19.464994

N/A

0DataRank · unranked

3 citations

Jing Wang, Bingliang Fang, Funda Meric‐Bernstam, Jack A. Roth, Min Jin Ha +1 more

TUSC2 immunogene enhances efficacy of chemo-immuno combination on KRAS/LKB1 mutant NSCLC in humanized mouse model

Communications Biology(2022)10.1038/s42003-022-03103-7

N/A

0DataRank · unranked

26 citations

Mourad Majidi, Ruping Shao, Feng Meng, Min Jin Ha, Elizabeth J. Shpall +2 more

CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts

Scientific Reports(2022)10.1038/s41598-022-16933-6

N/A

0DataRank · unranked

21 citations

Jing Wang, Bingliang Fang, Funda Meric‐Bernstam, Jack A. Roth, Min Jin Ha +1 more

Combined MEK/MDM2 inhibition demonstrates antitumor efficacy in TP53 wild-type thyroid and colorectal cancers with MAPK alterations

Scientific Reports(2022)10.1038/s41598-022-05193-z

N/A

0DataRank · unranked

9 citations

Argun Akçakanat, Scott Kopetz, Coya Tapia, Xiaofeng Zheng, Huiqin Chen +12 more

CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts

Research Square(2022)10.21203/rs.3.rs-1464274/v1

N/A

0DataRank · unranked

0 citations

Jing Wang, Bingliang Fang, Funda Meric‐Bernstam, Jack A. Roth, Min Jin Ha +1 more

Molecular parameters impacting the success rate of a lung cancer PDX model.

Journal of Clinical Oncology(2022)10.1200/jco.2022.40.16_suppl.e20592

N/A

0DataRank · unranked

0 citations

Shawna M. Hubert, Ran Zhang, Xingzhi Song, Tatiana V. Karpinets, Annikka Weissferdt +15 more

A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.26.512745

Top 100%

0DataRank

Top 100%0 citations

X. Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang +45 more

Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors

Science(2023)10.1126/science.abn4180

N/A

0DataRank · unranked

113 citations

Xuan Lu, Jin Cao, Qin Luo, Yao Ding, Fanglue Peng +34 more

Surgical outcomes after chemotherapy plus nivolumab and chemotherapy plus nivolumab and ipilimumab in patients with non–small cell lung cancer

Journal of Thoracic and Cardiovascular Surgery(2023)10.1016/j.jtcvs.2023.09.073

N/A

0DataRank · unranked

21 citations

Boris Sepesi, Cheuk Hong Leung, Heather Lin, Annikka Weissferdt, Apar Pataer +15 more

Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer

Nature Communications(2024)10.1038/s41467-024-47423-0

N/A

0DataRank · unranked

88 citations

Yu‐Ting Chou, Lauren Čech, Celia Fernández-Méndez, Johnny Yu, Victor Olivas +30 more

Mechanisms of Response and Tolerance to Active RAS Inhibition in KRAS -Mutant Non–Small Cell Lung Cancer

Cancer Discovery(2024)10.1158/2159-8290.cd-24-0421

N/A

0DataRank · unranked

67 citations

Ximo Pechuan-Jorge, Teng Zhou, Minh Truong, Xin Hu, Frank Rojas +22 more

Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-23-0471

N/A

0DataRank · unranked

21 citations

Michael W. Lloyd, Soner Koc, Yvonne A. Evrard, Lisa M. McShane, Michael T. Lewis +29 more

Programmed Death-Ligand 1 Heterogeneity and Its Impact on Benefit From Immune Checkpoint Inhibitors in NSCLC

Journal of Thoracic Oncology(2020)10.1016/j.jtho.2020.04.026

N/A

0DataRank · unranked

194 citations

Marcelo V. Negrão, Seyedeh Dibaj, Runzhe Chen, Alexandre Reuben, Jadi M. Bohac +32 more

Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance

Cancer Cell(2025)10.1016/j.ccell.2025.03.031

N/A

0DataRank · unranked

94 citations

Mingchuang Sun, Jun Cheng, Rui Ye, Zhengze Lu, Amber D. Horbath +21 more

Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target

Journal of Thoracic Oncology(2020)10.1016/j.jtho.2020.12.010

N/A

0DataRank · unranked

126 citations

Marcelo V. Negrão, Alexandre Reuben, Lorenzo Federico, Lixia Diao, Daniel J. McGrail +34 more

Agreement on Major Pathological Response in NSCLC Patients Receiving Neoadjuvant Chemotherapy

Clinical Lung Cancer(2020)10.1016/j.cllc.2019.11.003

N/A

0DataRank · unranked

114 citations

Apar Pataer, Ara A. Vaporciyan, Arlene M. Correa, Boris Sepesi, César A. Moran +10 more

LKB1/STK11 Expression in Lung Adenocarcinoma and Associations With Patterns of Recurrence

The Annals of Thoracic Surgery(2020)10.1016/j.athoracsur.2020.03.114

N/A

0DataRank · unranked

18 citations

Edwin R. Parra, Jiexin Zhang, David B. Nelson, Erin M. Corsini, Pamela Villalobos +22 more

Concurrent use of aspirin with osimertinib is associated with improved survival in advanced EGFR-mutant non-small cell lung cancer

Lung Cancer(2020)10.1016/j.lungcan.2020.08.023

N/A

0DataRank · unranked

20 citations

Lingzhi Hong, Monique B. Nilsson, Shawna M. Hubert, Shuhong Wu, Waree Rinsurongkawong +11 more

Genetic associations of T cell cancer immune response-related genes with T cell phenotypes and clinical outcomes of early-stage lung cancer

Journal for ImmunoTherapy of Cancer(2020)10.1136/jitc-2019-000336

N/A

0DataRank · unranked

15 citations

Jian Gu, Linbo Wang, David W. Chang, Yuanqing Ye, Maosheng Huang +3 more

Immune regulatory markers of lepidic-pattern adenocarcinomas presenting as ground glass opacities

Journal of Thoracic Disease(2020)10.21037/jtd.2020.01.42

N/A

0DataRank · unranked

8 citations

K. G. Mitchell, Jing Wang, Junya Fujimoto, Myrna C. B. Godoy, Carmen Behrens +16 more

Jack A. Roth

Indexed papers

Top data-sharing exemplar

Papers