Ira Pastan

Also affiliated with National Cancer Institute

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular BiologyEnvironmental Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 31 papers. Top paper: “Moxetumomab pasudotox in heavily pre-treated patients with relapsed/refractory hairy cell leukemia (HCL): long-term follow-up from the pivotal trial”.

Moxetumomab pasudotox in heavily pre-treated patients with relapsed/refractory hairy cell leukemia (HCL): long-term follow-up from the pivotal trial

Journal of Hematology & Oncology(2021)10.1186/s13045-020-01004-y

N/A

1.9DataRank · unranked

86 citations

Robert J. Kreitman, Claire Dearden, Pier Luigi Zinzani, Julio Delgado, Tadeusz Robak +14 more

Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models

Science Translational Medicine(2023)10.1126/scitranslmed.abn5649

N/A

0.853DataRank · unranked

30 citations

Charlotte McDowall, Luis Sánchez-Pérez, Cristina Osorio, Patrick C. Duncker, Aaron Briley +15 more

Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers

Frontiers in Oncology(2024)10.3389/fonc.2024.1386190

N/A

0.421DataRank · unranked

9 citations

Cody J. Peer, Xianyu Zhang, Hyoyoung Choo‐Wosoba, Mehwish Ahmad, Min-Jung Lee +13 more

Mapping drug distribution using CT imaging following direct tissue injection in ex vivo liver: informing clinical implementation

CVIR Oncology(2025)10.1007/s44343-025-00027-x

N/A

0.104DataRank · unranked

1 citations

Michal Mauda‐Havakuk, Jose F. Delgado, Michael Kassin, Azam Ghafoor, Ira Pastan +6 more

Enhanced efficacy of mesothelin-targeted immunotoxin LMB-100 and anti–PD-1 antibody in patients with mesothelioma and mouse tumor models

Science Translational Medicine(2020)10.1126/scitranslmed.aaz7252

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0DataRank · unranked

44 citations

Azam Ghafoor, Idrees Mian, Daniel Rathkey, Anish Thomas, Christine Alewine +8 more

Mechanisms of Resistance to Immunotoxins Containing Pseudomonas Exotoxin A in Cancer Therapy

Biomolecules(2020)10.3390/biom10070979

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0DataRank · unranked

38 citations

Ira Pastan, Michael Warren Dieffenbach

Development of Recombinant Immunotoxins for Hairy Cell Leukemia

Biomolecules(2020)10.3390/biom10081140

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0DataRank · unranked

26 citations

Ira Pastan, Robert J. Kreitman

Phase I study of mesothelin-targeted immunotoxin LMB-100 given as a long infusion with or without nab-paclitaxel.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.3553

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0DataRank · unranked

2 citations

Mehwish Ahmad, Yunkai Yu, Akira Yuno, Min-Jung Lee, Cody J. Peer +8 more

Paclitaxel synergizes with exposure time adjusted CD22-targeting immunotoxins against B-cell malignancies

UNC Libraries(2020)10.17615/akxp-j746

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0DataRank · unranked

0 citations

Tyler A. Cunningham, Fabian Müller, Ira Pastan, Stephanie Stookey

Targeted Cytotoxic Therapy Kills Persisting HIV Infected Cells During ART

UNC Libraries(2020)10.17615/fnnq-cv59

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0DataRank · unranked

0 citations

Yang Kuo, Olivia D. Snyder, David M. Margolis, Angela D. M. Kashuba, Paul W. Denton +12 more

Immunotherapy-based targeting of MSLN + activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2101270118

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0DataRank · unranked

29 citations

Yukinori Koyama, Xiao Liu, Sara Brin Rosenthal, Gen Yamamoto, Hiroaki Fuji +12 more

Moxetumomab pasudotox as re-treatment for heavily-pretreated relapsed hairy cell leukemia

Leukemia & lymphoma/Leukemia and lymphoma(2021)10.1080/10428194.2021.1929959

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0DataRank · unranked

13 citations

Steven Coutré, Hervé Ghesquières, Ira Pastan, Robert J. Kreitman, Ilana R. Yurkiewicz

Phase I study of mesothelin-targeted immunotoxin LMB-100 in combination with tofacitinib in persons with pancreatobiliary cancer or other mesothelin expressing solid tumors.

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.3_suppl.tps452

N/A

0DataRank · unranked

5 citations

Mehwish Ahmad, Seth M. Steinberg, Cody J. Peer, William D. Figg, David J. FitzGerald +4 more

Phase I study of mesothelin-targeted immunotoxin LMB-100 in combination with tofacitinib in patients with advanced pancreatobiliary cancer.

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.3051

N/A

0DataRank · unranked

4 citations

Mehwish Ahmad, Guillaume Joe Pegna, Cody J. Peer, Jane B. Trepel, Min-Jung Lee +9 more

Immunogenicity of Immunotoxins Containing Pseudomonas Exotoxin A: Causes, Consequences, and Mitigation

Frontiers in Immunology(2020)10.3389/fimmu.2020.01261

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0DataRank · unranked

90 citations

Ira Pastan, Ronit Mazor

Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2202439119

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0DataRank · unranked

50 citations

Masanori Onda, Nathan Watson, Raffit Hassan, Mitchell Ho, Tapan K. Bera +10 more

Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-22-0073

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0DataRank · unranked

46 citations

Jingli Zhang, Manakamana Khanal, Jessica Hong, Abhilash Venugopalan, Qun Jiang +7 more

GPC1-Targeted Immunotoxins Inhibit Pancreatic Tumor Growth in Mice via Depletion of Short-lived GPC1 and Downregulation of Wnt Signaling

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-21-0778

N/A

0DataRank · unranked

13 citations

Nan Li, Alex Renn, Hu Zhu, Lu Chen, Min Shen +5 more

557 The epitope-enhanced TARP peptide can induce specific T cells that can recognize wild-type TARP tetramer by either peptide or peptide-pulsed DC vaccination in patients with prostate cancer

Regular and Young Investigator Award Abstracts(2022)10.1136/jitc-2022-sitc2022.0557

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0DataRank · unranked

0 citations

Refika Turnier, Kimberly Dunham, Masaki Terabe, Seth M. Steinberg, Brenda Roberson +6 more

Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies

Cancer Research Communications(2023)10.1158/2767-9764.crc-22-0306

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0DataRank · unranked

27 citations

Dong Lin, Nathan Watson, Lothar Esser, Wai Kwan Tang, Alex Zhang +8 more

A tri-specific killer engager against mesothelin targets NK cells towards lung cancer

Frontiers in Immunology(2023)10.3389/fimmu.2023.1060905

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0DataRank · unranked

20 citations

Daniel A. Vallera, Brianna Ettestad, Caroline Hallstrom, Behiye Kodal, D.A. Todhunter +10 more

Analysis of systemic immune changes in patients with advanced cancer treated with immunotoxin LMB-100 and tofacitinib.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.e15017

N/A

0DataRank · unranked

1 citations

Cody J. Peer, Yunkai Yu, Min-Jung Lee, Sunmin Lee, Shraddha Rastogi +10 more

Data from Differential Cellular Internalization of Anti-CD19 and -CD22 Immunotoxins Results in Different Cytotoxic Activity

(2023)10.1158/0008-5472.c.6497313

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0DataRank · unranked

0 citations

Richard Beers, David Fitzgerald, Ira Pastan, Xing Du

Data from Killing of Resistant Cancer Cells with Low Bak by a Combination of an Antimesothelin Immunotoxin and a TRAIL Receptor 2 Agonist Antibody

(2023)10.1158/1078-0432.c.6519497

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0DataRank · unranked

0 citations

Laiman Xiang, Crystal L. Mackall, Ira Pastan, Xing Du

A Bispecific Antibody That Targets the Membrane-Proximal Region of Mesothelin and Retains High Anticancer Activity in the Presence of Shed Mesothelin

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-23-0233

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0DataRank · unranked

11 citations

Masanori Onda, T. O’Shea, Junxia Wei, Xiufen Liu, Tapan K. Bera +2 more

Complete Response in Hairy Cell Leukemia to Anti-CD22 CAR T-Cell Therapy

JCO Precision Oncology(2025)10.1200/po-25-00269

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0DataRank · unranked

2 citations

Brett Schroeder, Evgeny Arons, Constance M. Yuan, Hao‐Wei Wang, Mark Raffeld +15 more

RO4, a high-affinity humanized antibody against the juxtamembrane region of mesothelin for targeted cancer therapy

Antibody Therapeutics(2025)10.1093/abt/tbaf022

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0DataRank · unranked

2 citations

Xiufen Liu, Wenlong Liu, Jingyu Zhan, Carolyn Maslanka, Di Xia +3 more

Phase 1 trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox combined with rituximab for relapsed/refractory hairy cell leukemia.

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.7036

N/A

0DataRank · unranked

0 citations

Maryalice Stetler‐Stevenson, Constance M. Yuan, Hao‐Wei Wang, Hong Zhou, Mark Raffeld +10 more

Phase 1 study of the immunotoxin LMB‐100 in patients with mesothelioma and other solid tumors expressing mesothelin

Cancer(2020)10.1002/cncr.33145

N/A

0DataRank · unranked

62 citations

Christine Alewine, Idrees Mian, Anna Spreafico, Lillian L. Siu, Carlos Gomez‐Roca +13 more

Multiple proteases are involved in mesothelin shedding by cancer cells

Communications Biology(2020)10.1038/s42003-020-01464-5

N/A

0DataRank · unranked

52 citations

Alexander Chan, Chin‐Hsien Tai, Þorkell Andrésson, Ira Pastan, Xiufen Liu

Stabilization of hypoxia-inducible factor ameliorates glomerular injury sensitization after tubulointerstitial injury

Kidney International(2020)10.1016/j.kint.2020.09.031

N/A

0DataRank · unranked

16 citations

Jae Won Yang, Xiaoye Zhu, Jianyong Zhong, Ahmed Nagah El-Shaer, Taiji Matsusaka +5 more