Steven H. Zeisel

University of North Carolina at Chapel Hill

Also affiliated with David H. Murdock Research Institute

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 68 papers. Top paper: “Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder”.

Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder

Journal of Neurodevelopmental Disorders(2020)10.1186/s11689-020-09312-7

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2.6DataRank · unranked

116 citations

Birgit A. Fink, Anita J. Fuglestad, Judith K. Eckerle, Christopher J. Boys, Kristin E. Sandness +7 more

Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver

American Journal of Clinical Nutrition(2020)10.1093/ajcn/nqaa439

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0.973DataRank · unranked

23 citations

Sun‐Il Hwang, Julie M. Stegall, Walter B. Friday, David Kirchner, Steven H. Zeisel +1 more

Long-term follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder: corpus callosum white matter microstructure and neurocognitive outcomes

Journal of Neurodevelopmental Disorders(2022)10.1186/s11689-022-09470-w

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0.946DataRank · unranked

32 citations

Mary E. Anthony, Abigail M. Ernst, Donovan J. Roediger, Erik de Water, Judith K. Eckerle +8 more

Polymorphisms in SLC44A1 are associated with cognitive improvement in children diagnosed with fetal alcohol spectrum disorder: an exploratory study of oral choline supplementation

American Journal of Clinical Nutrition(2021)10.1093/ajcn/nqab081

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0.930DataRank · unranked

34 citations

Manjot S. Virdee, Judith K. Eckerle, Kristin E. Sandness, Michael Georgieff, Christopher J. Boys +3 more

Choline enhances elicited imitation memory performance in preschool children with prenatal alcohol exposure: a cumulative report of 3 randomized controlled trials

American Journal of Clinical Nutrition(2025)10.1016/j.ajcnut.2025.02.009

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0.344DataRank · unranked

7 citations

Judith K. Eckerle, Blake A. Gimbel, Abigail M. Ernst, Mary E. Anthony, Kent A. Tuominen +4 more

Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry

UNC Libraries(2020)10.17615/fw0a-ye89

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0DataRank · unranked

8 citations

Steven H. Zeisel, Jun Han, Jayanti R. Patel, J. Paul Speir, Christoph H. Borchers +5 more

A targeted metabolomic protocol for short-chain fatty acids and branched-chain amino acids

UNC Libraries(2020)10.17615/c4kt-fr56

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0DataRank · unranked

8 citations

Wei Jia, Qiong Li, Shanlei Qiao, Zhanxiang Zhou, Zhong Wei +9 more

Choline Dehydrogenase Polymorphism rs12676 Is a Functional Variation and Is Associated with Changes in Human Sperm Cell Function

UNC Libraries(2020)10.17615/k6kq-5a95

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0DataRank · unranked

3 citations

Amy Johnson, Tongwen Wang, Joseph A. Galanko, Sai Lao, Steven H. Zeisel

Nutrigenomics and metabolomics will change clinical nutrition and public health practice: insights from studies on dietary requirements for choline

UNC Libraries(2020)10.17615/5ytv-t718

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0DataRank · unranked

3 citations

Steven H. Zeisel

Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline

UNC Libraries(2020)10.17615/j95h-tm48

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0DataRank · unranked

5 citations

Jiannan Song, Steven H. Zeisel, Mei‐Heng Mar, Xiaonan ZHU, Lloyd J. Edwards

Understanding the Role of Nutrition in the Brain & Behavioral Development of Toddlers and Preschool Children: Identifying and Overcoming Methodological Barriers

UNC Libraries(2020)10.17615/rhkg-kr63

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0DataRank · unranked

4 citations

Steven H. Zeisel, J. Steven Reznick, Francisco Rosales

Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study

UNC Libraries(2020)10.17615/t1hq-wz79

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0DataRank · unranked

3 citations

Walter C. Willett, Eunyoung Cho, Lauren Dougherty, Graham A. Colditz, Paul F. Jacques +2 more

Dietary choline requirements of women: effects of estrogen and genetic variation

UNC Libraries(2020)10.17615/39tb-kw93

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0DataRank · unranked

1 citations

Kerry Ann Da Costa, Leslie M. Fischer, Lester Kwock, Steven H. Zeisel, Joseph A. Galanko

Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression

UNC Libraries(2020)10.17615/cva4-5454

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0DataRank · unranked

1 citations

Karen D. Corbin, Steven H. Zeisel

DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women

UNC Libraries(2020)10.17615/4v3n-3958

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0DataRank · unranked

1 citations

Sheila M. Innis, Darren Cole, Robert A. Waterland, Branwen J. Hennig, Anthony J. C. Fulford +7 more

Genetic polymorphisms in methyl-group metabolism and epigenetics: Lessons from humans and mouse models

UNC Libraries(2020)10.17615/39h1-8427

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0DataRank · unranked

1 citations

Steven H. Zeisel

Choline and Betaine Intake and the Risk of Colorectal Cancer in Men

UNC Libraries(2020)10.17615/454v-yd36

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0DataRank · unranked

0 citations

Edward L. Giovannucci, Charles S. Fuchs, Eunyoung Cho, Steven H. Zeisel, Walter C. Willett +1 more

Nutrition Education in U.S. Medical Schools: Latest Update of a National Survey

UNC Libraries(2020)10.17615/z646-g018

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0DataRank · unranked

0 citations

Steven H. Zeisel, Kelly McCutcheon Adams, Martin Kohlmeier

Diethanolamine alters neurogenesis and induces apoptosis in fetal mouse hippocampus

UNC Libraries(2020)10.17615/n37q-zb21

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0DataRank · unranked

0 citations

Ren’an Wu, Corneliu N. Craciunescu, Steven H. Zeisel

Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline

UNC Libraries(2020)10.17615/770j-9v33

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0DataRank · unranked

0 citations

Steven H. Zeisel

The association between betaine and choline intakes and the plasma concentrations of homocysteine in women

UNC Libraries(2020)10.17615/w9nq-jk92

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0DataRank · unranked

0 citations

Stephanie E. Chiuve, Edward L. Giovannucci, Steven H. Zeisel, Lauren Dougherty, Eric B. Rimm +2 more

Choline supplementation in children with fetal alcohol spectrum disorders: a randomized, double-blind, placebo-controlled trial

UNC Libraries(2020)10.17615/myz7-6c91

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0DataRank · unranked

0 citations

Jeffrey R. Wozniak, Birgit A. Fink, Christopher J. Boys, Neely C. Miller, Anita J. Fuglestad +7 more

Effects of a high daily dose of soy isoflavones on DNA damage, apoptosis, and estrogenic outcomes in healthy postmenopausal women: a phase I clinical trial

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/3b5j-ff55

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0DataRank · unranked

0 citations

Leslie M. Fischer, Elena Pop, April Coan, Steven H. Zeisel, Matt Gitzinger +1 more

Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma

UNC Libraries(2020)10.17615/jevv-x268

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0DataRank · unranked

0 citations

Leslie M. Fischer, Julie A. Vick, Joseph A. Galanko, Steven H. Zeisel, Wei Sha +2 more

Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load

UNC Libraries(2020)10.17615/wbj8-kd15

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0DataRank · unranked

0 citations

Christopher E. Gaffney, Leslie M. Fischer, Kerry Ann Da Costa, Steven H. Zeisel

Maternal nutrition at conception modulates DNA methylation of human metastable epialleles

UNC Libraries(2020)10.17615/vav4-7218

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0DataRank · unranked

0 citations

Maria S. Baker, Steven H. Zeisel, Robert A. Waterland, Eleonora Laritsky, Andrew W. Bergen +11 more

Choline deficiency increases lymphocyte apoptosis and DNA damage in humans

UNC Libraries(2020)10.17615/qhrt-8805

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0DataRank · unranked

0 citations

Mihai D. Niculescu, Corneliu N. Craciunescu, Kerry Ann Da Costa, Steven H. Zeisel, Leslie M. Fischer

A Brief History of Choline

UNC Libraries(2020)10.17615/9kej-n581

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0DataRank · unranked

0 citations

Steven H. Zeisel

Mouse Betaine-Homocysteine S -Methyltransferase Deficiency Reduces Body Fat via Increasing Energy Expenditure and Impairing Lipid Synthesis and Enhancing Glucose Oxidation in White Adipose Tissue

UNC Libraries(2020)10.17615/g612-6f68

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0DataRank · unranked

0 citations

Jessica M. Ellis, Rosalind Coleman, Ya Wen Teng, Steven H. Zeisel

Dietary isoflavones differentially induce gene expression changes in lymphocytes from postmenopausal women who form equol as compared with those who do not

UNC Libraries(2020)10.17615/y6bd-de84

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0DataRank · unranked

0 citations

Steven H. Zeisel, Elena Pop, Mihai D. Niculescu, Leslie M. Fischer

Dietary choline deficiency causes DNA strand breaks and alters epigenetic marks on DNA and histones

UNC Libraries(2020)10.17615/t1h5-v468

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0DataRank · unranked

0 citations

Steven H. Zeisel

What Choline Metabolism Can Tell Us About the Underlying Mechanisms of Fetal Alcohol Spectrum Disorders

UNC Libraries(2020)10.17615/pakc-bn50

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0DataRank · unranked

0 citations

Steven H. Zeisel

Regulation of Choline Deficiency Apoptosis by Epidermal Growth Factor in CWSV-1 Rat Hepatocytes

UNC Libraries(2020)10.17615/3tsw-rq06

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0DataRank · unranked

0 citations

Steven H. Zeisel, Kerry Ann Da Costa, Erich Klem, Craig D. Albright, Mei‐Heng Mar +1 more

Highlights of the 2012 Research Workshop: Using Nutrigenomics and Metabolomics in Clinical Nutrition Research

UNC Libraries(2020)10.17615/nj09-ga77

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0DataRank · unranked

0 citations

José M. Ordovás, Wei Jia, Deborah M. Muoio, Robert A. Waterland, Steven H. Zeisel +1 more

Epigenetic mechanisms for nutrition determinants of later health outcomes

UNC Libraries(2020)10.17615/kfpg-vv36

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0DataRank · unranked

0 citations

Steven H. Zeisel

Maternal dietary choline availability alters the balance of netrin-1 and DCC neuronal migration proteins in fetal mouse brain hippocampus

UNC Libraries(2020)10.17615/v3d4-q477

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0DataRank · unranked

0 citations

Corneliu N. Craciunescu, Jiannan Song, Steven H. Zeisel, Craig D. Albright, Mei‐Heng Mar

Perinatal Choline Influences Brain Structure and Function

UNC Libraries(2020)10.17615/3pca-v327

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0DataRank · unranked

0 citations

Steven H. Zeisel, Mihai D. Niculescu

Are dietary choline and betaine intakes determinants of total homocysteine concentration?

UNC Libraries(2020)10.17615/yz0e-6x87

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0DataRank · unranked

0 citations

Jung Eun Lee, Steven H. Zeisel, Eunyoung Cho, Paul F. Jacques, Lauren Dougherty +2 more

Nutritional Genomics: Defining the Dietary Requirement and Effects of Choline

UNC Libraries(2020)10.17615/b83t-tx80

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0DataRank · unranked

0 citations

Steven H. Zeisel

Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains

UNC Libraries(2020)10.17615/ps81-1n85

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0DataRank · unranked

0 citations

Mihai D. Niculescu, Steven H. Zeisel, Corneliu N. Craciunescu

Aberrant Estrogen Regulation of PEMT Results in Choline Deficiency-associated Liver Dysfunction

UNC Libraries(2020)10.17615/za0b-pd51

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0DataRank · unranked

0 citations

Joseph A. Galanko, Mukund Patel, Ian J. Davis, Mary Resseguie, Kerry Ann Da Costa +1 more

Choline Availability During Embryonic Development Alters Progenitor Cell Mitosis in Developing Mouse Hippocampus

UNC Libraries(2020)10.17615/f9g9-gm67

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0DataRank · unranked

0 citations

Jiannan Song, Steven H. Zeisel, Corneliu N. Craciunescu, Craig D. Albright, Mei‐Heng Mar

Ad Libitum Choline Intake in Healthy Individuals Meets or Exceeds the Proposed Adequate Intake Level

UNC Libraries(2020)10.17615/kzpa-ce65

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0DataRank · unranked

0 citations

Steven H. Zeisel, Jayanti R. Patel, Leslie M. Fischer, Beth MacIntosh, Julie A. Scearce +3 more

Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not

UNC Libraries(2020)10.17615/5bds-v877

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0DataRank · unranked

0 citations

Steven H. Zeisel, Mihai D. Niculescu, Kerry Ann Da Costa, Leslie M. Fischer

Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial

UNC Libraries(2020)10.17615/58kr-7330

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0DataRank · unranked

0 citations

Carol L. Cheatham, Barbara Davis Goldman, Kerry Ann Da Costa, J. Steven Reznick, Steven H. Zeisel +1 more

Status of nutrition education in medical schools

UNC Libraries(2020)10.17615/keba-1w15

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0DataRank · unranked

0 citations

Steven H. Zeisel, Martin Kohlmeier, Karen Lindell, Kelly McCutcheon Adams

Dose Response Effects of Dermally applied Diethanolamine on Neurogenesis in Fetal Mouse Hippocampus and Potential Exposure of Humans

UNC Libraries(2020)10.17615/qhdp-7373

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0DataRank · unranked

0 citations

Mihai D. Niculescu, Steven H. Zeisel, Leslie M. Fischer, Guo Zhong, Amy R. Johnson +1 more

GSTM1, GSTT1, GSTP1, and GSTA1 Polymorphisms and Urinary Isothiocyanate Metabolites following Broccoli Consumption in Humans

UNC Libraries(2020)10.17615/v063-7784

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0DataRank · unranked

0 citations

Marilie D. Gammon, Denise Wall, James R. Hébert, Susan E. Steck, Steven H. Zeisel

Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclin-dependent kinase inhibitor 3 gene

UNC Libraries(2020)10.17615/54nf-1119

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0DataRank · unranked

0 citations

Mihai D. Niculescu, Yutaka Yamamuro, Steven H. Zeisel

Choline: Clinical Nutrigenetic/Nutrigenomic Approaches for Identification of Functions and Dietary Requirements

UNC Libraries(2020)10.17615/mfj3-4g02

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0DataRank · unranked

0 citations

Steven H. Zeisel

Common genetic polymorphisms affect the human requirement for the nutrient choline

UNC Libraries(2020)10.17615/jkg8-ed86

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0DataRank · unranked

0 citations

Joseph A. Galanko, Kerry Ann Da Costa, Steven H. Zeisel, Jiannan Song, Olga G. Kozyreva +1 more

Inadequate intake of nutrients essential for neurodevelopment in children with fetal alcohol spectrum disorders (FASD)

UNC Libraries(2020)10.17615/trm6-x444

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0DataRank · unranked

0 citations

Birgit A. Fink, Michael Georgieff, Christopher J. Boys, Anita J. Fuglestad, Heather L. Hoecker +4 more

Metabolic crosstalk between choline/1-carbon metabolism and energy homeostasis

UNC Libraries(2020)10.17615/n2vp-v922

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0DataRank · unranked

0 citations

Steven H. Zeisel

Choline, Other Methyl-Donors and Epigenetics

UNC Libraries(2020)10.17615/vq5a-r169

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0DataRank · unranked

0 citations

Steven H. Zeisel

The fetal origins of memory: The role of dietary choline in optimal brain development

UNC Libraries(2020)10.17615/6qf4-3s04

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0DataRank · unranked

0 citations

Steven H. Zeisel

The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic

UNC Libraries(2020)10.17615/g8ca-5n87

N/A

0DataRank · unranked

0 citations

Mihai D. Niculescu, Rebecca C. Fry, Miroslav Stýblo, Michael P. Waalkes, David S. Paul +5 more

The supply of choline is important for fetal progenitor cells

UNC Libraries(2021)10.17615/mk0f-nj32

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0DataRank · unranked

0 citations

Steven H. Zeisel

Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency.

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2022)10.17615/fhms-hn67

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0DataRank · unranked

131 citations

Bernd Schwahn, Jacques Genest, M. D. Laryea, Rima Rozen, Steven H. Zeisel +6 more

Valuing the Diversity of Research Methods to Advance Nutrition Science

Advances in Nutrition(2022)10.1093/advances/nmac043

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0DataRank · unranked

40 citations

Sylvia Rowe, Sarah D. Ohlhorst, Andrew W. Brown, Daniël J. Hoffman, DeAnn Liska +13 more

Role of a SER immune suppressor in immune surveillance

PubMed(2022)10.17615/qw98-9w11

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0DataRank · unranked

22 citations

Oh, S.K., Jennifer L. Walker, S. D. Ross, Steven H. Zeisel

A grand challenge for nutrigenomics

UNC Libraries(2022)10.17615/vczt-ve13

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0DataRank · unranked

0 citations

Steven H. Zeisel

Dietary docosahexaenoic acid supplementation modulates hippocampal development in the pemt-/- mouse

UNC Libraries(2022)10.17615/c3t1-6y13

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0DataRank · unranked

0 citations

Kerry Ann Da Costa, Kunal Rai, Corneliu N. Craciunescu, Steven H. Zeisel, Kishan S. Parikh +3 more

Genetic admixture predictors of fetal alcohol spectrum disorders (FASD) in a South African population

Gene(2024)10.1016/j.gene.2024.148854

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0DataRank · unranked

2 citations

Zikun Yang, Tugba Akkaya-Hocagil, Sandra W. Jacobson, Joseph L. Jacobson, Neil C. Dodge +6 more

Choline and betaine concentrations in plasma predict dietary choline intake in healthy humans: a double-blind randomized control feeding study

medRxiv(2025)10.1101/2025.07.15.25331567

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0DataRank · unranked

3 citations

David A. Horita, Julie M. Stegall, Rachel Coble, Evan M. Paules, Anju Lulla +7 more

Nutrition in Medicine: Nutrition Education for Medical Students and Residents

UNC Libraries(2020)10.17615/j02w-d350

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0DataRank · unranked

33 citations

Margo Powell, Steven H. Zeisel, Martin Kohlmeier, Kelly McCutcheon Adams

Phosphatidylethanolamine N -methyltransferase ( PEMT ) gene expression is induced by estrogen in human and mouse primary hepatocytes

UNC Libraries(2020)10.17615/f2k7-kb30

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0DataRank · unranked

14 citations

Thomas A. Randall, Mihai D. Niculescu, Mary Resseguie, Jiannan Song, Kerry‐Ann da Costa +1 more

Cholineʼs role in maintaining liver function: new evidence for epigenetic mechanisms

UNC Libraries(2020)10.17615/thsm-2e55

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0DataRank · unranked

12 citations

Mihai G. Mehedint, Steven H. Zeisel

Choline metabolism and risk of breast cancer in a population-based study

UNC Libraries(2020)10.17615/ara3-wc63

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0DataRank · unranked

6 citations

Jia Chen, Yin Leng Lee, Steven H. Zeisel, Marilie D. Gammon, Patrick T. Bradshaw +5 more