Stephen Y. Chan

Also affiliated with Cardiovascular Institute of the South, Cardiovascular Institute Hospital, University of Pittsburgh Medical Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 64 papers. Top paper: “Matrix stiffening induces a pathogenic QKI-miR-7-SRSF1 signaling axis in pulmonary arterial endothelial cells”.

Matrix stiffening induces a pathogenic QKI-miR-7-SRSF1 signaling axis in pulmonary arterial endothelial cells

American Journal of Physiology-Lung Cellular and Molecular Physiology(2021)10.1152/ajplung.00407.2020

N/A

0.903DataRank · unranked

27 citations

Neha Hafeez, Adam Handen, Ying Tang, Lloyd D. Harvey, Leonard E. Estephan +5 more

Comparison of Contemporary Risk Scores in All Groups of Pulmonary Hypertension

CHEST Journal(2024)10.1016/j.chest.2024.03.018

N/A

0.901DataRank · unranked

38 citations

Henning Gall, Meike Fünderich, Martin R. Wilkins, Luke Howard, David G. Kiely +49 more

Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension

Cellular and Molecular Immunology(2021)10.1038/s41423-020-00608-1

N/A

0.675DataRank · unranked

89 citations

Jingsi Zhao, Yi‐Yin Tai, Sathish Babu Vasamsetti, Scott O'Neil, Rahul Kumar +11 more

Frataxin deficiency promotes endothelial senescence in pulmonary hypertension

Journal of Clinical Investigation(2021)10.1172/jci136459

N/A

0.654DataRank · unranked

77 citations

Jingsi Zhao, Yi‐Yin Tai, Ying Tang, Dror Perk, Vinny Negi +26 more

A systems‐level study reveals host‐targeted repurposable drugs against SARS‐CoV‐2 infection

Molecular Systems Biology(2021)10.15252/msb.202110239

N/A

0.538DataRank · unranked

35 citations

Qingya Shi, Fen Pei, Andreas Vogt, Rebecca A. Porritt, Gustavo Garcia +11 more

Modeling of dilated cardiomyopathy by establishment of isogenic human iPSC lines carrying phospholamban C25T (R9C) mutation (UPITTi002-A-1) using CRISPR/Cas9 editing

Stem Cell Research(2021)10.1016/j.scr.2021.102544

N/A

0.432DataRank · unranked

9 citations

Nan Ma, Ying Tang, Michael P. Haugh, Laila S. Alamri, Stephen Y. Chan +2 more

SCUBE1 Controls BMPR2-Relevant Pulmonary Endothelial Function

JACC Basic to Translational Science(2020)10.1016/j.jacbts.2020.08.010

N/A

0.373DataRank · unranked

11 citations

Ying Tang, Yi‐Yin Tai, Adam Handen, Jingsi Zhao, Gil Speyer +24 more

Studying the Pulmonary Endothelium in Health and Disease: An Official American Thoracic Society Workshop Report

American Journal of Respiratory Cell and Molecular Biology(2024)10.1165/rcmb.2024-0330st

N/A

0.373DataRank · unranked

11 citations

Cristina M. Alvira, Julie A. Bastarache, Serpil C. Erzurum, Wolfgang M. Kuebler, Eric P. Schmidt +29 more

Frataxin deficiency disrupts mitochondrial respiration and pulmonary endothelial cell function

Vascular Pharmacology(2023)10.1016/j.vph.2023.107181

N/A

0.312DataRank · unranked

7 citations

Rashmi J. Rao, Monica Mehta, Jingsi Zhao, Wadih El Khoury, Lloyd D. Harvey +9 more

Association between income and likelihood of right heart catheterization in individuals with pulmonary hypertension: A US claims database analysis

Pulmonary Circulation(2022)10.1002/pul2.12132

N/A

0.269DataRank · unranked

5 citations

Gretchen Swabe, Stephen Y. Chan, Jared W. Magnani, Erin Schikowski

Single Nucleotide Polymorphism rs9277336 Controls the Nuclear Alpha Actinin 4‐Human Leukocyte Antigen‐DPA1 Axis and Pulmonary Endothelial Pathophenotypes in Pulmonary Arterial Hypertension

Journal of the American Heart Association(2023)10.1161/jaha.122.027894

N/A

0.269DataRank · unranked

5 citations

Anna Kirillova, Yunshan Yue, Rashmi Rao, Neil J. Kelly, Wadih El Khoury +17 more

NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification

Journal of the American College of Cardiology(2021)10.1016/j.jacc.2021.02.056

N/A

0DataRank · unranked

20 citations

Anna R. Hemnes, Micheala A. Aldred, John Barnard, Evan L. Brittain, Stephen Y. Chan +26 more

Improved hospitalization rates in a specialty center for heart failure with preserved ejection fraction and pulmonary hypertension

Pulmonary Circulation(2021)10.1002/pul2.12002

N/A

0DataRank · unranked

2 citations

Hongyang Pi, Adam Handen, Erin Schikowski, Yimin Chen, Floyd Thoma +5 more

VEGF receptor promotes hypoxia-induced hematopoietic progenitor proliferation and differentiation

Research Square(2021)10.21203/rs.3.rs-1000955/v1

N/A

0DataRank · unranked

2 citations

Scott O'Neil, Sathish Babu Vasamsetti, Lee L. Ohayon, Anagha Arunkumar, Samit Ghosh +6 more

Metabolomic Profiles of Scleroderma-PAH are different than idiopathic PAH and associated with worse clinical outcomes

medRxiv(2021)10.1101/2021.07.10.21259355

N/A

0DataRank · unranked

0 citations

Junzhe Shao, Michael W. Pauciulo, William C. Nichols, Anna R. Hemnes, Atul Malhotra +12 more

Loss of Amphiregulin drives inflammation and endothelial apoptosis in pulmonary hypertension

Life Science Alliance(2022)10.26508/lsa.202101264

N/A

0DataRank · unranked

37 citations

Jingsi Zhao, Yi‐Yin Tai, Wei Sun, Lee L Ohayon, Scott O'Neil +10 more

Metabolomic Profiles Differentiate Scleroderma-PAH From Idiopathic PAH and Correspond With Worsened Functional Capacity

CHEST Journal(2022)10.1016/j.chest.2022.08.2230

N/A

0DataRank · unranked

26 citations

Junzhe Shao, Michael W. Pauciulo, William C. Nichols, Anna R. Hemnes, Atul Malhotra +14 more

Post-GWAS functional analysis identifies CUX1 as a regulator of p16INK4a and cellular senescence

Nature Aging(2022)10.1038/s43587-022-00177-0

N/A

0DataRank · unranked

25 citations

Wei Sun, Ting Wu, Meijuan Zou, Sathish Babu Vasamsetti, Xiaoyu Zhang +15 more

VEGF Receptor 1 Promotes Hypoxia-Induced Hematopoietic Progenitor Proliferation and Differentiation

Frontiers in Immunology(2022)10.3389/fimmu.2022.882484

N/A

0DataRank · unranked

22 citations

Scott O'Neil, Lee L. Ohayon, Afaz Uddin, Sathish Babu Vasamsetti, Anagha Arunkumar +7 more

Association Between Copayment and Adherence to Medications for Pulmonary Arterial Hypertension

Journal of the American Heart Association(2022)10.1161/jaha.122.026620

N/A

0DataRank · unranked

14 citations

Gretchen Swabe, Stephen Y. Chan, Jared W. Magnani, Erin Schikowski

Metabolic Maturation Exaggerates Abnormal Calcium Handling in a Lamp2 Knockout Human Pluripotent Stem Cell-Derived Cardiomyocyte Model of Danon Disease

Biomolecules(2022)10.3390/biom13010069

N/A

0DataRank · unranked

12 citations

Qing Liu, Ying Tang, Michael P. Haugh, Jeffery Cui, Stephen Y. Chan +2 more

miRNA/mRNA co-profiling identifies the miR-200 family as a central regulator of SMC quiescence

iScience(2022)10.1016/j.isci.2022.104169

N/A

0DataRank · unranked

11 citations

Cristina Espinosa‐Díez, Mingjun Liu, Ibrahim A. Ahmed, Sidney Mahan, Jianxin Wei +4 more

Pulmonary Arterial Hypertension: Emerging Principles of Precision Medicine across Basic Science to Clinical Practice

Reviews in Cardiovascular Medicine(2022)10.31083/j.rcm2311378

N/A

0DataRank · unranked

11 citations

Stephen Y. Chan, Neil J. Kelly

Circulating hypoxia-dependent miR-210 is increased in clinical sepsis subtypes: A cohort study

Journal of Translational Medicine(2022)10.1186/s12967-022-03655-6

N/A

0DataRank · unranked

9 citations

Yi‐Yin Tai, Jason Kennedy, Christopher W. Seymour, Stephen Y. Chan, Rachel E Powell

Defenestrated endothelium delays liver-directed gene transfer in hemophilia A mice

Blood Advances(2022)10.1182/bloodadvances.2021006388

N/A

0DataRank · unranked

6 citations

Eun-Mi Ju, Shweta Gudapati, Ravi Vats, Sanya Arshad, Rikesh K. Dubey +12 more

miR-roring Changes in Blood: miR-210 Reflects Hypoxic Disease Dynamics in Obstructive Sleep Apnea

American Journal of Respiratory and Critical Care Medicine(2022)10.1164/rccm.202209-1709ed

N/A

0DataRank · unranked

2 citations

Stephen Y. Chan, Anna Kirillova

A dUTY to Protect: Addressing “Y” We See Sex Differences in Pulmonary Hypertension

American Journal of Respiratory and Critical Care Medicine(2022)10.1164/rccm.202204-0653ed

N/A

0DataRank · unranked

2 citations

Stephen Y. Chan, Rashmi Rao

The Role of EBP50 in Regulating Endothelial-To-Mesenchymal Transition in Pulmonary Hypertension

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.31.494181

N/A

0DataRank · unranked

0 citations

Mariah Berman, Maryam Sharifi‐Sanjani, Andrés Pulgarin, Anas Alsuraimi, Patricia Riva +23 more

Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases

Journal of Extracellular Vesicles(2023)10.1002/jev2.12305

N/A

0DataRank · unranked

118 citations

Tianji Chen, James E. Dahlman, Lola Eniola‐Adefeso, Ionita Ghiran, Peter Kurre +24 more

Profiling of repetitive RNA sequences in the blood plasma of patients with cancer

Nature Biomedical Engineering(2023)10.1038/s41551-023-01081-7

N/A

0DataRank · unranked

49 citations

Sreelakshmi Velandi Maroli, Vikas Peddu, Andrew E. Davidson, Alexander Hill, Erin LaMontagne +5 more

Automated detection and segmentation of pulmonary embolisms on computed tomography pulmonary angiography (CTPA) using deep learning but without manual outlining

Medical Image Analysis(2023)10.1016/j.media.2023.102882

N/A

0DataRank · unranked

34 citations

Naciye Sinem Gezer, Shangsi Ren, Aylin Özgen Alpaydın, Emre Ruhat Avcı, Michael G. Risbano +4 more

A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3

iScience(2023)10.1016/j.isci.2023.105935

N/A

0DataRank · unranked

17 citations

Mehboob Ali, Bryce Piper, Mingjun Liu, Jaylen Hudson, Neil J. Kelly +14 more

Innovations in RNA therapy for hemophilia

Blood(2023)10.1182/blood.2022018661

N/A

0DataRank · unranked

14 citations

Stephen Y. Chan, Margaret V. Ragni

Effects of ranolazine on right ventricular function, fluid dynamics, and metabolism in patients with precapillary pulmonary hypertension: insights from a longitudinal, randomized, double-blinded, placebo controlled, multicenter study

Frontiers in Cardiovascular Medicine(2023)10.3389/fcvm.2023.1118796

N/A

0DataRank · unranked

12 citations

Paul R. Forfia, Anjali Vaidya, Gautam Ramani, Robert A. deKemp, Robert H. Mach +7 more

Omics and Extreme Phenotyping Reveal Longitudinal Association Between Left Atrial Size and Pulmonary Vascular Resistance in Group 2 Pulmonary Hypertension

Journal of the American Heart Association(2023)10.1161/jaha.123.031746

N/A

0DataRank · unranked

2 citations

David Newhouse, Himal Chapagain, Ashish Patel, Yicheng Tang, Ato Howard +10 more

Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness

Cell Metabolism(2024)10.1016/j.cmet.2024.04.010

N/A

0DataRank · unranked

33 citations

Ying Tang, Yi-Yin Tai, Jingsi Zhao, Caroline Chauvet, Julien Grynblat +29 more

Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension

Science Translational Medicine(2024)10.1126/scitranslmed.add2029

N/A

0DataRank · unranked

23 citations

Qiujun Yu, Ying Tang, Wei Sun, Neil J. Kelly, Satoshi Okawa +47 more

A Roadmap for Therapeutic Discovery in Pulmonary Hypertension Associated with Left Heart Failure. A Scientific Statement of the Heart Failure Association (HFA) of the ESC and the ESC Working Group on Pulmonary Circulation & Right Ventricular Function

European Journal of Heart Failure(2024)10.1002/ejhf.3236

N/A

0DataRank · unranked

23 citations

Valentina Mercurio, Piero Pollesello, Markus S. Anker, Johannes Backs, Antoni Bayés‐Genís +35 more

Reversal of inflammatory reprogramming by vasodilator agents in pulmonary hypertension

ERJ Open Research(2024)10.1183/23120541.00486-2024

N/A

0DataRank · unranked

1 citations

Meena Sethuraman, Xishuang Dong, Almina Kirdar, Gil Speyer, Yassmin Al Aaraj +8 more

Pulmonary primary oxysterol and bile acid synthesis as a predictor of outcomes in pulmonary arterial hypertension

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.20.576474

N/A

0DataRank · unranked

5 citations

Lloyd D. Harvey, William C. Nichols, Michael W. Pauciulo, Anna R. Hemnes, Tao Long +16 more

Mitigation of Stress-induced Structural Remodeling and Functional Deficiency in iPSC-CMs with PLN R9C Mutation by Promoting Autophagy

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.17.589921

N/A

0DataRank · unranked

1 citations

Robert J. Barndt, Yawei Shen, Karim Sallam, Ying Tang, Stephen Y. Chan +4 more

Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.26.582142

N/A

0DataRank · unranked

0 citations

Mona Alotaibi, Hee-Jung Janice Kim, Yi‐Yin Tai, Ying Tang, Wei Sun +24 more

Frataxin deficiency in the astrocytes drives neurocognitive impairment in sickle cell disease mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.20.629760

N/A

0DataRank · unranked

0 citations

Shane C Lenhart, Lesley M. Foley, Nandinii Sekar, Paritosh Mondal, Hong Wang +6 more

Lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension

Science(2025)10.1126/science.adn7277

N/A

0DataRank · unranked

47 citations

Mona Alotaibi, Yi‐Yin Tai, Ying Tang, Hee‐Jung J. Kim, Neil J. Kelly +46 more

Endothelial ADAR1 Deficit Induces the NOCT-IRF7 Axis in Pulmonary Hypertension

Circulation Research(2025)10.1161/circresaha.125.326277

N/A

0DataRank · unranked

7 citations

Giovanni Maroli, Hyunbum Kim, Yi‐Yin Tai, Ying Tang, Satoshi Okawa +23 more

Deficiency of Smooth Muscle Adar1 Exacerbates Vascular Remodeling and Pulmonary Hypertension

Circulation Research(2025)10.1161/circresaha.125.326235

N/A

0DataRank · unranked

6 citations

Giovanni Maroli, Chen-Shan Chen Woodcock, Hyunbum Kim, Yu Liu, Tim Klouda +24 more

Deep Learning Predicts Cardiac Output from Seismocardiographic Signals in Heart Failure

The American Journal of Cardiology(2025)10.1016/j.amjcard.2025.09.037

N/A

0DataRank · unranked

4 citations

Seyed M. Nouraie, Neil J. Kelly, Stephen Y. Chan, Jesse Wang

Male survival disadvantage in pulmonary hypertension: independent of aetiology, age, disease severity, comorbidities and treatment

EBioMedicine(2025)10.1016/j.ebiom.2025.106063

N/A

0DataRank · unranked

2 citations

Jeffrey Annis, Meike Fünderich, Jochen Wilhelm, David G. Kiely, Luke Howard +71 more

Associations of sleep-associated variants with wearable-derived sleep stages in the All of Us research program

SLEEP(2025)10.1093/sleep/zsaf209

N/A

0DataRank · unranked

3 citations

Seyed Mehdi Nouraie, Stephen Y. Chan, Neil J. Kelly, Irene N Chan

Bidirectional Crosstalk Between Sleep and Pulmonary Arterial Hypertension

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.23.666314

N/A

0DataRank · unranked

1 citations

Aymen Halouani, Jacob Dahlka, Nathan Burgess, Samar Antar, You‐Yang Zhao +5 more

Identifying Metabolomic Biomarkers of Lung Function Decline in People with HIV

JAIDS Journal of Acquired Immune Deficiency Syndromes(2025)10.1097/qai.0000000000003689

N/A

0DataRank · unranked

0 citations

Stacy G. Wendell, Barbara A. Methé, Steven J. Mullett, Biying Zhang, Kelvin Li +8 more

Deep learning predicts cardiac output from seismocardiographic signals in heart failure

medRxiv(2025)10.1101/2025.07.11.25331386

N/A

0DataRank · unranked

0 citations

Mehdi Nouraie, Neil J. Kelly, Stephen Y. Chan, Jesse Wang

Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension

Pulmonary Circulation(2020)10.1177/2045894020908782

N/A

0DataRank · unranked

121 citations

Tracy Tabib, Humberto E. Trejo Bittar, Eleanor Valenzi, John Sembrat, Stephen Y. Chan +3 more

Health outcomes after national acute sleep deprivation events among the American public

JCI Insight(2025)10.1172/jci.insight.195344

N/A

0DataRank · unranked

0 citations

Rahul Chaudhary, Wadih El Khoury, Nishita Kalepalli, Jesse Wang, Priya Patel +9 more

Outcomes of Pulmonary Arterial Hypertension Are Improved in a Specialty Care Center

CHEST Journal(2020)10.1016/j.chest.2020.01.046

N/A

0DataRank · unranked

35 citations

Chad M. Kosanovich, Adam Handen, Michael Tao, Jacqueline Visina, Gabrielle Vanspeybroeck +10 more

Ranolazine Improves Right Ventricular Function in Patients With Precapillary Pulmonary Hypertension: Results From a Double-Blind, Randomized, Placebo-Controlled Trial

Journal of Cardiac Failure(2020)10.1016/j.cardfail.2020.10.006

N/A

0DataRank · unranked

44 citations

Paul R. Forfia, Anjali Vaidya, Jeremy A. Mazurek, Myung H. Park, Gautam Ramani +3 more

Long Range Endocrine Delivery of Circulating miR-210 to Endothelium Promotes Pulmonary Hypertension

Circulation Research(2020)10.1161/circresaha.119.316398

N/A

0DataRank · unranked

38 citations

Jonathan Florentin, Yi‐Yin Tai, Stéphanie Torrino, Lee Ohayon, Tomasz Brzóska +11 more

Biophysical forces rewire cell metabolism to guide microtubule-dependent cell mechanics

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.10.985036

N/A

0DataRank · unranked

2 citations

Stéphane Audebert, Ilyes Belhadj, Caroline Lacoux, Sabrina Pisano, Sophie Abélanet +6 more

Single-cell RNA sequencing profiling of mouse endothelial cells in response to pulmonary arterial hypertension

Cardiovascular Research(2021)10.1093/cvr/cvab296

N/A

0DataRank · unranked

145 citations

Shiau-Haln Chen, Jessica P. Scanlon, João P Monteiro, Axelle Caudrillier, Sweta Sweta +21 more

Mechano-induced cell metabolism promotes microtubule glutamylation to force metastasis

Cell Metabolism(2021)10.1016/j.cmet.2021.05.009

N/A

0DataRank · unranked

133 citations

Eloïse M. Grasset, Stéphane Audebert, Ilyes Belhadj, Caroline Lacoux, Meagan Haynes +9 more

Metabolic Syndrome Mediates ROS-miR-193b-NFYA–Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction

Circulation(2021)10.1161/circulationaha.121.053889

N/A

0DataRank · unranked

86 citations

Longfei Wang, Cristina Espinosa‐Díez, Bing Wang, Scott Hahn, Kentaro Noda +20 more

Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension

Science Advances(2021)10.1126/sciadv.abh3794

N/A

0DataRank · unranked

39 citations

Jimin Yang, Gil Speyer, Andrés Pulgarin, Adam Handen, Jingsi Zhao +26 more

Simultaneous Pharmacologic Inhibition of Yes‐Associated Protein 1 and Glutaminase 1 via Inhaled Poly(Lactic‐co‐Glycolic) Acid–Encapsulated Microparticles Improves Pulmonary Hypertension

Journal of the American Heart Association(2021)10.1161/jaha.120.019091

N/A

0DataRank · unranked

38 citations

Ying Tang, Thomas Bertero, Yi‐Yin Tai, Lloyd D. Harvey, Chen‐Shan C. Woodcock +7 more

Increased Mortality in Patients With Preoperative and Persistent Postoperative Pulmonary Hypertension Undergoing Mitral Valve Surgery for Mitral Regurgitation: A Cohort Study

Journal of the American Heart Association(2021)10.1161/jaha.120.018394

N/A

0DataRank · unranked

19 citations

Daniel Shpilsky, Adam Handen, Gabrielle Vanspeybroeck, Ann Canterbury, Michael T. Lu +7 more