Michael B Yaffe

Roswell Park Comprehensive Cancer Center

Also affiliated with Beth Israel Deaconess Medical Center, Harvard University, Moffitt Cancer Center, Precision for Medicine (United States), Cancer Research Center, Laboratoire d’immunologie intégrative du cancer, Center for Cancer Research, Massachusetts Institute of Technology

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 41 papers. Top paper: “Is there a role for tissue plasminogen activator as a novel treatment for refractory COVID-19 associated acute respiratory distress syndrome?”.

Is there a role for tissue plasminogen activator as a novel treatment for refractory COVID-19 associated acute respiratory distress syndrome?

The Journal of Trauma: Injury, Infection, and Critical Care(2020)10.1097/ta.0000000000002694

N/A

5.1DataRank · unranked

86 citations

Christopher D. Barrett, Ernest E. Moore, Robert C. McIntyre, Peter K. Moore, Daniel Talmor +3 more

Study of alteplase for respiratory failure in severe acute respiratory syndrome coronavirus 2/COVID‐19: Study design of the phase IIa STARS trial

Research and Practice in Thrombosis and Haemostasis(2020)10.1002/rth2.12395

N/A

1.1DataRank · unranked

24 citations

Christopher D. Barrett, Ernest E. Moore, Rashi Jhunjhunwala, Robert C. McIntyre, Peter K. Moore +6 more

Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer

Cancer Immunology Research(2021)10.1158/2326-6066.cir-20-0922

N/A

0.650DataRank · unranked

75 citations

Thejaswini Giridharan, Kelly L. Singel, A. Nazmul H. Khan, Jason Ricciuti, Kaitlyn Howard +22 more

Early Immune Changes Support Signet Ring Cell Dormancy in CDH1 -Driven Hereditary Diffuse Gastric Carcinogenesis

Molecular Cancer Research(2023)10.1158/1541-7786.mcr-23-0122

N/A

0.533DataRank · unranked

12 citations

Lauren A. Gamble, Laurence P. Diggs, Darryl Nousome, Jesse C. Patterson, Brian A. Joughin +9 more

Redox priming promotes Aurora A activation during mitosis

Science Signaling(2020)10.1126/scisignal.abb6707

N/A

0.524DataRank · unranked

32 citations

Vladimir Joukov, T.J. Rettenmaier, Akiko Kumagai, William G. Dunphy, James A. Wells +2 more

Influence of Tranexamic Acid on Inflammatory Signaling in Trauma

Seminars in Thrombosis and Hemostasis(2020)10.1055/s-0040-1702169

N/A

0.477DataRank · unranked

23 citations

Yi Wen Kong, Michael B Yaffe, Christopher D. Barrett

Circulating Factors in Trauma Plasma Activate Specific Human Immune Cell Subsets

Injury(2020)10.1016/j.injury.2020.03.009

N/A

0.385DataRank · unranked

12 citations

Fei Guo, Jennifer P. Nguyen, Fan Zhang, Anupamaa Seshadri, Joshua Keegan +7 more

An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.28.538590

N/A

0.330DataRank · unranked

8 citations

Karl A. Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Erika D. Handly +15 more

A rebrand for proteasome inhibition in solid tumors via continuous hepatic artery infusion

JCI Insight(2025)10.1172/jci.insight.199200

N/A

0.104DataRank · unranked

1 citations

Jack H. Victory, Priyanka P. Desai, Lindsay R. Friedman, H. Stepp, Robynne Ashe +14 more

Inducing DNA damage through R-loops to kill cancer cells

Molecular & Cellular Oncology(2020)10.1080/23723556.2020.1848233

N/A

0DataRank · unranked

13 citations

Yi Wen Kong, Michael B Yaffe, Fred C. Lam

The Injury Response to DNA Damage Promotes Anti-Tumor Immunity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.26.062216

N/A

0DataRank · unranked

2 citations

Lauren E. Milling, Jung-Kuei Chen, Wuhbet Abraham, Erika D. Handly, Darrell J. Irvine +2 more

Intratumoral administration of DNA-damaging chemotherapy-treated tumor cells to enhance therapeutic benefit of systemic immune checkpoint blockade in mouse cancer models.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.5_suppl.77

N/A

0DataRank · unranked

0 citations

Lauren E. Milling, Jung-Kuei Chen, Wuhbet Abraham, Darrell J. Irvine, Michael B Yaffe +1 more

Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses

Cell Reports Medicine(2021)10.1016/j.xcrm.2021.100478

N/A

0DataRank · unranked

80 citations

Yoram Vodovotz, Sultan Abdelhamid, Francis X. Guyette, Michael B Yaffe, Danielle S. Gruen +23 more

MAPKAP Kinase-2 Drives Expression of Angiogenic Factors by Tumor-Associated Macrophages in a Model of Inflammation-Induced Colon Cancer

Frontiers in Immunology(2021)10.3389/fimmu.2020.607891

N/A

0DataRank · unranked

32 citations

Yi Wen Kong, Ganapathy Sriram, Jesse C. Patterson, Samantha G. Rosenberg, Sandra Morandell +3 more

Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain – binding peptide macrocycles

Organic & Biomolecular Chemistry(2021)10.1039/d1ob01120k

N/A

0DataRank · unranked

10 citations

Kohei Tsuji, Robert A. Grant, Ramesh Chingle, Dominique L. Kunciw, Michael B Yaffe +2 more

A haem-sequestering plant peptide promotes iron uptake in symbiotic bacteria

Nature Microbiology(2022)10.1038/s41564-022-01192-y

N/A

0DataRank · unranked

68 citations

Vignesh M. P. Babu, Ke Bian, Areej Alhhazmi, Mary C. Andorfer, Dante Avalos +7 more

Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

Cancer Research(2022)10.1158/0008-5472.can-22-1533

N/A

0DataRank · unranked

22 citations

Andreas Varkaris, Peter J.P. Croucher, Maya Ridinger, Susan L. Dalrymple, Mannan Nouri +14 more

Direct capture of neutralized RBD enables rapid point-of-care assessment of SARS-CoV-2 neutralizing antibody titer

Cell Reports Methods(2022)10.1016/j.crmeth.2022.100273

N/A

0DataRank · unranked

16 citations

Orville O. Kirkland, Seven Bohannon, Daniel Lim, Robert M. Wilson, Edward J. Richards +18 more

An Integrated Pharmacological, Structural, and Genetic Analysis of Extracellular Versus Intracellular ROS Production in Neutrophils

Journal of Molecular Biology(2022)10.1016/j.jmb.2022.167533

N/A

0DataRank · unranked

10 citations

Ingred Riça, Jacob S. Kim, Yu‐ming M. Huang, Daniel Lim, Tanya Mitra +12 more

Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.1c01359

N/A

0DataRank · unranked

8 citations

Jung‐Eun Park, Young Jin Ham, Daniel Lim, Nicholas Kwiatkowski, Do‐Hee Kim +13 more

Immunogenic cell stress and injury versus immunogenic cell death: implications for improving cancer treatment with immune checkpoint blockade

Molecular & Cellular Oncology(2022)10.1080/23723556.2022.2039038

N/A

0DataRank · unranked

2 citations

Tiffany R. Emmons, Lauren E. Milling, Darrell J. Irvine, Michael B Yaffe, Ganapathy Sriram

Polo-like kinase-1 Inhibitors and the Antiandrogen Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.12.491633

N/A

0DataRank · unranked

0 citations

Andreas Varkaris, Peter J.P. Croucher, Maya Ridinger, Susan L. Dalrymple, Mannan Nouri +14 more

Biphasic JNK–Erk Signaling Separates Induction and Maintenance of Cell Senescence after DNA Damage

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.15.496288

N/A

0DataRank · unranked

0 citations

Gerard J. Ostheimer, Andrea R. Tentner, Peter K. Sorger, Kevin A. Janes, Douglas A. Lauffenburger +2 more

Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition

Cell Systems(2023)10.1016/j.cels.2023.06.005

N/A

0DataRank · unranked

30 citations

Gerard J. Ostheimer, Andrea R. Tentner, Brian A. Joughin, Alexandra M. Dakoyannis, Charvi D. Sharma +5 more

Cytomegalovirus durably primes neutrophil oxidative burst

Journal of Leukocyte Biology(2023)10.1093/jleuko/qiad091

N/A

0DataRank · unranked

3 citations

Michael Dombek, Michael Gutknecht, Marion Grießl, Ingred Riça, Barbora Vlková +11 more

MAPKAP Kinase-2 phosphorylation of PABPC1 controls its interaction with 14-3-3 proteins after DNA damage: A combined kinase and protein array approach

Frontiers in Molecular Biosciences(2023)10.3389/fmolb.2023.1148933

N/A

0DataRank · unranked

1 citations

Scott Floyd, Erik Wilker, Hans Christian Reinhardt, Scott M. Clarke, Qiuying Huang +5 more

Data from ROS Fusion Tyrosine Kinase Activates a SH2 Domain–Containing Phosphatase-2/Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Signaling Axis to Form Glioblastoma in Mice

(2023)10.1158/0008-5472.c.6494688

N/A

0DataRank · unranked

0 citations

Erik Wilker, Margaret E. McLaughlin, Keara Lane, Ram Gowda, Shanie Coven +7 more

Data from Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer

(2023)10.1158/2326-6066.c.6550174

N/A

0DataRank · unranked

0 citations

Thejaswini Giridharan, Kelly L. Singel, ANM Nazmul H. Khan, Jason Ricciuti, Kaitlyn Howard +22 more

Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis

Nature Communications(2024)10.1038/s41467-024-45167-5

N/A

0DataRank · unranked

54 citations

Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang +6 more

Expression of IMPACT Curtails Metabolic Plasticity and Augments NK Cell Killing to Abrogate Metastatic Growth

Cancer Discovery(2025)10.1158/2159-8290.cd-24-1055

N/A

0DataRank · unranked

2 citations

Abir K. Panda, Rodrigo Xavier das Neves, Zeribe C. Nwosu, Ke Xu, Elke van Beek +59 more

A simple circuit to sustain intact tumor microenvironments for complex drug interrogations

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.26.684624

N/A

0DataRank · unranked

0 citations

Samantha M. Ruff, Kirsten Remmert, Martha E. Teke, Emily A. Verbus, Areeba Saif +57 more

Faculty Opinions recommendation of PtdIns(4,5)P2 functions at the cleavage furrow during cytokinesis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature(2005)10.3410/f.1028014.335925

N/A

0DataRank · unranked

0 citations

Michael B Yaffe

Author response: Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs

(2019)10.7554/elife.44635.025

N/A

0DataRank · unranked

0 citations

Pau Creixell, Anne van Vlimmeren, Brian A. Joughin, Chad J Miller, Nasir Haider +6 more

BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage

Nature Communications(2020)10.1038/s41467-020-17503-y

N/A

0DataRank · unranked

149 citations

Yi Wen Kong, Qiuying Huang, Tu-Lan Vu Han, Amanda Maffa, Ekkehard M. Kasper +2 more

Transite: A Computational Motif-Based Analysis Platform That Identifies RNA-Binding Proteins Modulating Changes in Gene Expression

Cell Reports(2020)10.1016/j.celrep.2020.108064

N/A

0DataRank · unranked

60 citations

Molly A. Bird, Shohreh Varmeh, Erika D. Handly, Anna Gattinger, Thomas Bernwinkler +7 more

Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints

Nature Communications(2020)10.1038/s41467-020-17958-z

N/A

0DataRank · unranked

48 citations

Erik C. Dreaden, Sandra Morandell, Wen Zhou, Sanjeev Dhara, Ganapathy Sriram +13 more

Salvage use of tissue plasminogen activator (tPA) in the setting of acute respiratory distress syndrome (ARDS) due to COVID-19 in the USA: a Markov decision analysis

World Journal of Emergency Surgery(2020)10.1186/s13017-020-00305-4

N/A

0DataRank · unranked

36 citations

Christopher D. Barrett, Hunter B. Moore, Ernest E. Moore, Robert C. McIntyre, Peter K. Moore +4 more

Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model

Journal of Thrombosis and Haemostasis(2020)10.1111/jth.14875

N/A

0DataRank · unranked

48 citations

Shauna M. Dineen, Stephen C. Van Nostrand, Madison K. Kuhn, Christopher D. Barrett, Douglas K. Brubaker +4 more

Development of Rapid Response Capabilities in a Large COVID-19 Alternate Care Site Using Failure Modes and Effect Analysis with In Situ Simulation

Anesthesiology(2020)10.1097/aln.0000000000003521

N/A

0DataRank · unranked

16 citations

Liana Zucco, Richard J. Ehrlichman, Ronald E. Hirschberg, Stacy Johnson, Michael B Yaffe +4 more

Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division

Nature Communications(2020)10.1038/s41467-020-18769-y

N/A

0DataRank · unranked

38 citations

Georgios Katsikis, Zhaoqi Li, Kiera M. Sapp, Max A. Stockslager, Daniel Lim +5 more

Influence of tranexamic acid on the complement system in trauma

ANZ Journal of Surgery(2020)10.1111/ans.15538

N/A

0DataRank · unranked

3 citations

Michael B Yaffe, Christopher D. Barrett