Adrianne Wallace-Povirk

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 6 papers. Top paper: “Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors”.

Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116093

N/A

0DataRank · unranked

12 citations

Nian Tong, Jennifer Wong-Roushar, Carrie O’Connor, Xilin Zhou, Zhanjun Hou +8 more

Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment

Scientific Reports(2022)10.1038/s41598-022-14788-5

N/A

0DataRank · unranked

15 citations

Lisa Rubinsak, Agnes Malysa, Sijana H. Dzinic, Manasa Ravindra, Mathew Schneider +11 more

Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases

Science Translational Medicine(2023)10.1126/scitranslmed.abn9674

N/A

0DataRank · unranked

15 citations

Jessica E. Gianopulos, Zachary Schrank, Sarah M. Cavender, Stephanie Dobersch, Bryan D. Kynnap +15 more

Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00763

N/A

0DataRank · unranked

17 citations

Jade M. Katinas, Tejashree Magdum, Khushbu Shah, Jennifer E. Wong, Carrie O’Connor +7 more

Multitargeted 6-Substituted Thieno[2,3-d]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism

ACS Pharmacology & Translational Science(2023)10.1021/acsptsci.3c00020

N/A

0DataRank · unranked

6 citations

Jennifer Wong-Roushar, Adrianne Wallace-Povirk, Yesha V. Shah, Morgan C. Nyman, Jade M. Katinas +10 more

Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-23-0550

N/A

0DataRank · unranked

15 citations

Carrie O’Connor, Aamod S. Dekhne, Xun Bao, Md. Junayed Nayeen, Mathew Schneider +11 more