🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Kyle R. Brimacombe

National Institutes of Health

ORCID: 0000-0002-9629-1417
Computer ScienceBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile
3.3Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Real-time sharing of drug screening data on the NCATS OpenData Portal accelerates translational research

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.04.135046
Top 7%
3.3DataRank
Top 7%108 citations

Tongan Zhao, Richard T. Eastman, Xin Hu, Ke Wang, Mark Backus +31 more

Papers

Driven by 11 papers — median percentile 93. Top paper: “Real-time sharing of drug screening data on the NCATS OpenData Portal accelerates translational research”.

Real-time sharing of drug screening data on the NCATS OpenData Portal accelerates translational research

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.04.135046
Top 7%
3.3DataRank
Top 7%108 citations

Tongan Zhao, Richard T. Eastman, Xin Hu, Ke Wang, Mark Backus +31 more

Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit

The Journal of Infectious Diseases(2021)10.1093/infdis/jiab305
N/A
2.2DataRank · unranked
41 citations

James M. Anderson, Annaliesa S. Anderson, David Baker, Jay Bradner, Kyle R. Brimacombe +37 more

Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00916
N/A
1.7DataRank · unranked
63 citations

Daniel J. Urban, Bryan T. Mott, Xin Hu, Shyh‐Ming Yang, Gloria A. Benavides +40 more

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2005463117
N/A
0.581DataRank · unranked
47 citations

Adam Yasgar, T Teramoto, Myoung‐Hwa Lee, Dorjbal Dorjsuren, Richard T. Eastman +13 more

Remdesivir: A Review of Its Discovery and Development Leading to Human Clinical Trials for Treatment of COVID-19

Preprints.org(2020)10.20944/preprints202004.0299.v1
N/A
0DataRank · unranked
18 citations

Jacob S. Roth, Kyle R. Brimacombe, Anton Simeonov, Min Shen, Samarjit Patnaik +2 more

The National Center for Advancing Translational Sciences’ Intramural Training Program and Fellow Career Outcomes

CBE—Life Sciences Education(2020)10.1187/cbe.20-03-0048
N/A
0DataRank · unranked
9 citations

Kyle R. Brimacombe, Christy Hare, Jessica M. Faupel‐Badger, Brittany Haynes

Discovery and Optimization of 2H-1λ2-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00019
N/A
0DataRank · unranked
29 citations

Karavadhi Surendra, Rajan Pragani, Li Liu, Yuhong Fang, Weihe Zhang +28 more

Optimization of ether and aniline based inhibitors of lactate dehydrogenase

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.127974
N/A
0DataRank · unranked
5 citations

Kwangho Kim, Somnath Jana, Ian M. Romaine, Ganesha Rai, Bryan T. Mott +18 more

The NCATS Assay Guidance Manual programme: advancing the practice and rigour of preclinical translation

Nature Reviews Drug Discovery(2022)10.1038/d41573-022-00170-7
N/A
0DataRank · unranked
4 citations

Kyle R. Brimacombe, G. Sitta Sittampalam, A Grossman, Nathan P. Coussens, James Inglese +5 more

Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development

The Journal of Infectious Diseases(2023)10.1093/infdis/jiad334
N/A
0DataRank · unranked
7 citations

Stephanie L. Ford‐Scheimer, Rodolfo Alarcón, Anthony Atala, Jeffrey T. Borenstein, Kyle R. Brimacombe +23 more

A deep learning approach predicting the activity of COVID-19 therapeutics and vaccines against emerging variants

npj Systems Biology and Applications(2024)10.1038/s41540-024-00471-0
N/A
0DataRank · unranked
5 citations

Işın Y. Comba, Eli Silvert, Michiel J.M. Niesen, Karthik Murugadoss, Dhruti Patwardhan +8 more