Jacob D. Estes

Also affiliated with Oregon Health & Science University, Children's Cancer Therapy Development Institute, Vaccine and Gene Therapy Institute

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 66 papers. Top paper: “SARS-CoV-2 infection protects against rechallenge in rhesus macaques”.

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

Science(2020)10.1126/science.abc4776

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1.0DataRank · unranked

924 citations

Jinyan Liu, Amanda J. Martinot, Katherine McMahan, Noe B. Mercado, Lauren Peter +48 more

A Foundation Model for Spatial Proteomics

arXiv (Cornell University)(2025)10.48550/arxiv.2506.03373

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0.292DataRank · unranked

6 citations

Yuzhou Chang, Huaying Qiu, Yao Yu Yeo, Guillaume Jaume, Yuchen Wang +55 more

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

Nature(2020)10.1038/s41586-020-1946-0

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0DataRank · unranked

196 citations

Maud Mavigner, Lavinia Franchitti, S. Abigail Smith, Erick White, Gregory K. Tharp +23 more

Recommendations for measuring HIV reservoir size in cure-directed clinical trials

Nature Medicine(2020)10.1038/s41591-020-1022-1

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0DataRank · unranked

140 citations

Douglas D. Richman, Robert F. Siliciano, Michel C. Nussenzweig, Bonnie J. Howell, Javier Martínez‐Picado +29 more

Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters

Nature Medicine(2020)10.1038/s41591-020-1070-6

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0DataRank · unranked

322 citations

Frank Wegmann, Amanda J. Martinot, Carolin Loos, Katherine McMahan, Noe B. Mercado +39 more

Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques

Cell(2020)10.1016/j.cell.2020.10.005

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226 citations

Kathleen Busman‐Sahay, Samuel J. Vidal, Zoltan Maliga, Stephen Bondoc, Carly E. Starke +22 more

CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption

Nature Medicine(2020)10.1038/s41591-020-0782-y

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0DataRank · unranked

106 citations

Shari N. Gordon, Chi Ngai Chan, Hong Wang, Emily Lindemuth, Cristin M. Galardi +25 more

HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells

Nature Immunology(2020)10.1038/s41590-020-0593-9

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96 citations

Lawrence M. Lifshitz, Kyle Gellatly, Carol L. Vinton, Kathleen Busman‐Sahay, Sean Matthew McCauley +16 more

Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge

PLoS Pathogens(2020)10.1371/journal.ppat.1008764

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48 citations

Dominic Paquin‐Proulx, Maria Montero, Kristina K. Peachman, Xiaoying Shen, Lindsay Wieczorek +28 more

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

PLoS Pathogens(2020)10.1371/journal.ppat.1008339

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64 citations

Jhomary Molden, Kathleen Busman‐Sahay, Shaheed Abdulhaqq, Helen L. Wu, Whitney C. Weber +17 more

Application of a Scavenger Receptor A1-Targeted Polymeric Prodrug Platform for Lymphatic Drug Delivery in HIV

Molecular Pharmaceutics(2020)10.1021/acs.molpharmaceut.0c00562

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19 citations

Pavan P. Adiseshaiah, Siva Sai Krishna Dasa, Tim Potter, Sarah L. Skoczen, Kelsie S. Snapp +11 more

Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1

UNC Libraries(2020)10.17615/a4t2-9t30

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14 citations

Angela Padgett‐Thomas, Jacob D. Estes, Mary Zupancic, Anja K. Wege, Michael W. Melkus +5 more

Prolonged Posttreatment Virologic Control and Complete Seroreversion After Advanced Human Immunodeficiency Virus-1 Infection

Open Forum Infectious Diseases(2020)10.1093/ofid/ofaa613

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10 citations

Isabel Cassetti, Neena Kashyap, Claire Deléage, Jacob D. Estes, Christopher Trindade +18 more

African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity

PLoS Pathogens(2020)10.1371/journal.ppat.1008333

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42 citations

Fredrik Barrenäs, Cuiling Xu, Kathleen Busman‐Sahay, Audrey Valentine, G. Lynn Law +11 more

Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection

PLoS Pathogens(2020)10.1371/journal.ppat.1008744

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37 citations

Jennifer M. Zerbato, Wei Zhao, Sabine Braat, Claire Deléage, Surekha Tennakoon +13 more

In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome

PLoS Pathogens(2020)10.1371/journal.ppat.1008666

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37 citations

Eisa Mahyari, Craig N. Kreklywich, Luke S. Uebelhoer, Matthew R. McArdle, Matilda J. Moström +30 more

Next-generation Viral RNA/DNA in situ Hybridization Applications in Human Immunodeficiency Virus/Simian Immunodeficiency Virus Research

Journal of Visualized Experiments(2020)10.3791/60318

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6 citations

David R. Morcock, Jacob D. Estes, Claire Deléage, Catherine Brands

Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

UNC Libraries(2020)10.17615/vqpf-py88

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1 citations

Jacob D. Estes, Florence A. Othieno, Ashley T. Haase, Daniel A. Powell, Bangdong L. Wei +5 more

Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells

Nature(2020)10.1038/s41586-020-2002-9

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0DataRank · unranked

28 citations

Maud Mavigner, Lavinia Franchitti, S. Abigail Smith, Erick White, Gregory K. Tharp +23 more

Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.16.300277

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0DataRank · unranked

5 citations

María Pino, Arun K. Boddapati, Elise G. Viox, Carly E. Starke, Amit A. Upadhyay +38 more

In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.02.129486

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0DataRank · unranked

2 citations

Eisa Mahyari, Craig N. Kreklywich, Luke S. Uebelhoer, Matthew R. McArdle, Matilda J. Moström +27 more

JoVE Video Dataset

(2020)10.3791/60318-v

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0DataRank · unranked

0 citations

David R. Morcock, Jacob D. Estes, Claire Deléage, Catherine Brands

TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma

Cell Host & Microbe(2021)10.1016/j.chom.2021.02.005

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90 citations

Kristin N. Adams, Courtney R. Plumlee, Caleb Stoltzfus, Laila Shehata, Albanus O. Moguche +8 more

Adjacent Cell Marker Lateral Spillover Compensation and Reinforcement for Multiplexed Images

Frontiers in Immunology(2021)10.3389/fimmu.2021.652631

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63 citations

Bokai Zhu, Xavier Rovira‐Clavé, Han Chen, Maxim Markovic, Chi Ngai Chan +7 more

Eliminating HIV reservoirs for a cure: the issue is in the tissue

Current Opinion in HIV and AIDS(2021)10.1097/coh.0000000000000688

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62 citations

Carly E. Starke, Michael Nekorchuk, Jacob D. Estes, Kathleen Busman‐Sahay

CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification

Journal of Clinical Investigation(2021)10.1172/jci141677

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39 citations

Derick D. Duell, Yoshinori Fukazawa, Benjamin Varco-Merth, Alejandra Marenco, Hannah Michaela Behrens +19 more

Evaluating a New Class of AKT/mTOR Activators for HIV Latency-Reversing Activity Ex Vivo and In Vivo

Journal of Virology(2021)10.1128/jvi.02393-20

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25 citations

Roland Schwarzer, William Brantley, Benjamin Varco-Merth, Hannah S. Sperber, Philip A. Hull +27 more

A Randomized, Placebo-Controlled Trial Assessing the Effect of VISBIOME ES Probiotic in People With HIV on Antiretroviral Therapy

Open Forum Infectious Diseases(2021)10.1093/ofid/ofab550

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19 citations

Eunice Yeh, Brett Williams, Alan Landay, Jeffrey M. Jacobson, Cara C. Wilson +12 more

Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection

PLoS Pathogens(2021)10.1371/journal.ppat.1009674

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17 citations

Amit A. Upadhyay, Hasse Walum, Chi Ngai Chan, Reem Dawoud, Christine Grech +17 more

Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques

PLoS Pathogens(2021)10.1371/journal.ppat.1009565

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0DataRank · unranked

15 citations

Kathleen Busman‐Sahay, Stephen Bondoc, David Morrow, Alexandra M. Ortiz, Christine M. Fennessey +18 more

Antibody-mediated depletion of viral reservoirs is limited in SIV-infected macaques treated early with antiretroviral therapy

Journal of Clinical Investigation(2021)10.1172/jci142421

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0DataRank · unranked

23 citations

Taina T. Immonen, Kelli Oswald, Cathi Pyle, James A. Thomas, William J. Bosche +22 more

Quantitative Imaging Analysis of the Spatial Relationship between Antiretrovirals, Reverse Transcriptase Simian-Human Immunodeficiency Virus RNA, and Collagen in the Mesenteric Lymph Nodes of Nonhuman Primates

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.00019-21

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0DataRank · unranked

8 citations

Joseph N. Mwangi, Gabriela De la Cruz, Michael Nekorchuk, Chi Ngai Chan, Kathleen Busman‐Sahay +7 more

Multiparameter immunohistochemistry analysis of HIV DNA, RNA and immune checkpoints in lymph node tissue

Journal of Immunological Methods(2021)10.1016/j.jim.2021.113198

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7 citations

Claire Deléage, Candani Tutuka, Marzena Walkiewicz, Perla M. Del Río Estrada, Rachel D. Pascoe +10 more

Combined protein and nucleic acid imaging reveals virus-dependent B cell and macrophage immunosuppression of tissue microenvironments

Immunity(2022)10.1016/j.immuni.2022.03.020

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92 citations

Chi Ngai Chan, Xavier Rovira‐Clavé, Han Chen, Yunhao Bai, Bokai Zhu +27 more

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy

Journal of Clinical Investigation(2022)10.1172/jci155251

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48 citations

Susan Pereira Ribeiro, Chi Ngai Chan, Malika Aïd, Claire Deléage, Luca Micci +21 more

Myeloid cell tropism enables MHC-E–restricted CD8 + T cell priming and vaccine efficacy by the RhCMV/SIV vaccine

Science Immunology(2022)10.1126/sciimmunol.abn9301

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40 citations

Meaghan H. Hancock, Daniel Malouli, Emily E. Marshall, Colette M. Hughes, Kurt T. Randall +24 more

IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health

JCI Insight(2022)10.1172/jci.insight.153046

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26 citations

Ashish Sharma, Khader Ghneim, Susan Pereira Ribeiro, Peter Wilkinson, Richard M. Dunham +9 more

Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus–infected rhesus macaques on antiretroviral therapy

Journal of Clinical Investigation(2022)10.1172/jci156063

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0DataRank · unranked

19 citations

William Brantley, Alejandra Marenco, Derick D. Duell, Devin N. Fachko, Brian Richardson +17 more

Evidence of cancer therapy-induced chronic inflammation in the ovary across multiple species: A potential cause of persistent tissue damage and follicle depletion

Journal of Reproductive Immunology(2022)10.1016/j.jri.2022.103491

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15 citations

Zaira Carranza, Yi Luan, Kathleen Busman‐Sahay, Shally Wolf, Shawn Campbell +6 more

Non-Human Primate Models of HIV Brain Infection and Cognitive Disorders

Viruses(2022)10.3390/v14091997

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0DataRank · unranked

13 citations

Thomas A. Angelovich, Kathleen Busman‐Sahay, Catherine R. Cochrane, Michael Roche, Jacob D. Estes +2 more

Quantitative Imaging Analysis of the Spatial Relationship between Antiretrovirals, Reverse Transcriptase Simian-Human Immunodeficiency Virus RNA, and Fibrosis in the Spleens of Nonhuman Primates

Antimicrobial Agents and Chemotherapy(2022)10.1128/aac.00609-22

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7 citations

Nicole White, Y. Desyaterik, Gabriela De la Cruz, Michael Nekorchuk, Margaret Terry +8 more

Antiretroviral drug exposure in lymph nodes is heterogeneous and drug dependent

Journal of the International AIDS Society(2022)10.1002/jia2.25895

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18 citations

Claire Deléage, Nicole White, Craig Sykes, Catherine Brands, Lourdes Adamson +4 more

Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques

PLoS Pathogens(2022)10.1371/journal.ppat.1009990

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0DataRank · unranked

8 citations

Samuel J. Vidal, César Piedra-Mora, Sarah Ducat, Chi Ngai Chan, Stephen Bondoc +8 more

Novel Lymphocytic Choriomeningitis Virus Strain Sustains Abundant Exhausted Progenitor CD8 T Cells without Systemic Viremia

The Journal of Immunology(2022)10.4049/jimmunol.2200320

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6 citations

Milcah C. Scott, Mark Pierson, Vineet Joag, Sathi Wijeyesinghe, Matthew R. Semler +8 more

In Situ Multiplexing to Identify, Quantify, and Phenotype the HIV-1/SIV Reservoir Within Lymphoid Tissue

Methods in molecular biology(2022)10.1007/978-1-0716-1871-4_19

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0DataRank · unranked

1 citations

Michael Nekorchuk, Carly E. Starke, Chi Ngai Chan, Jacob D. Estes, Kathleen Busman‐Sahay

Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.21.512606

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9 citations

Elise G. Viox, Amit A. Upadhyay, Zachary Strongin, Gregory K. Tharp, María Pino +33 more

In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Nature Medicine(2023)10.1038/s41591-023-02213-x

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155 citations

Elena Knops, Leon Cords, Nadine Lübke, María Salgado, Kathleen Busman‐Sahay +31 more

Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4+ and CD8+ T cells

Cell Host & Microbe(2023)10.1016/j.chom.2023.08.006

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83 citations

Olivier Tastet, Caroline Dufour, Gérémy Sannier, Nathalie Brassard, Gloria-Gabrielle Delgado +10 more

Regional Analysis of Intact and Defective HIV Proviruses in the Brain of Viremic and Virally Suppressed People with HIV

Annals of Neurology(2023)10.1002/ana.26750

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28 citations

Catherine R. Cochrane, Jingling Zhou, Carolin Tumpach, Sarah J. Byrnes, Janna Jamal Eddine +13 more

Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques

Science Immunology(2023)10.1126/sciimmunol.adg0033

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28 citations

Timothy N. Hoang, Amit A. Upadhyay, Rayhane Nchioua, Maximilian Hirschenberger, Zachary Strongin +37 more

Allogeneic immunity clears latent virus following allogeneic stem cell transplantation in SIV-infected ART-suppressed macaques

Immunity(2023)10.1016/j.immuni.2023.04.019

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24 citations

Kathleen Busman‐Sahay, Whitney C. Weber, Courtney Waytashek, Carla Boyle, Katherine B. Bateman +38 more

Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques

PLoS Pathogens(2023)10.1371/journal.ppat.1011290

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14 citations

Kathleen Busman‐Sahay, Thomas A. Angelovich, Skyler Younger, Sol Taylor-Brill, Michael Nekorchuk +13 more

Prolonged experimental CD4+ T-cell depletion does not cause disease progression in SIV-infected African green monkeys

Nature Communications(2023)10.1038/s41467-023-36379-2

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13 citations

Paola Sette, Cuiling Xu, Andrew R. Rahmberg, Lilas Tarnus, Haritha Annapureddy +12 more

Lymph-Node-Based CD3 + CD20 + Cells Emerge from Membrane Exchange between T Follicular Helper Cells and B Cells and Increase Their Frequency following Simian Immunodeficiency Virus Infection

Journal of Virology(2023)10.1128/jvi.01760-22

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10 citations

Ankita Chowdhury, Tomas Raul Wiche Salinas, Perla M. Del Río Estrada, Morgan A. Reuter, Gregory K. Tharp +11 more

Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques

PLoS Pathogens(2023)10.1371/journal.ppat.1011343

N/A

0DataRank · unranked

0 citations

Kathleen Busman‐Sahay, Stephen Bondoc, David Morrow, Alexandra M. Ortiz, Christine M. Fennessey +18 more

Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption

Nature Immunology(2024)10.1038/s41590-024-01952-4

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23 citations

Zachary Strongin, Hugo Soudeyns, Felipe ten-Caten, Khader Ghneim, Gabriela Pacheco Sánchez +25 more

Engineered deletions of HIV replicate conditionally to reduce disease in nonhuman primates

Science(2024)10.1126/science.adn5866

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24 citations

Elizabeth J. Tanner, Neha Khetan, Gustavo Vasen, Clara Levrel, Arjun J. Kumar +22 more

Impact of Dolutegravir Plus Lamivudine as First-line Antiretroviral Treatment on the Human Immunodeficiency Virus Type 1 Reservoir and Inflammatory Markers in Peripheral Blood

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae530

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12 citations

María C. Puertas, Maria C. García-Guerrero, Igor Moraes-Cardoso, Ester Aparicio, Yovaninna Alarcón‐Soto +31 more

CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles

UNC Libraries(2024)10.17615/m4sm-kk61

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10 citations

Yunbo Wei, Sharon R. Lewin, Anurag Atnerkar, Iain Comerford, Claire Deléage +32 more

Rapid systemic spread and minimal immune responses following SIVsab intrarectal transmission in African green monkeys

JCI Insight(2024)10.1172/jci.insight.183751

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4 citations

Cuiling Xu, Claire Deléage, Dongzhu Ma, Benjamin B. Policicchio, Egidio Brocca‐Cofano +7 more

Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence

PLoS Pathogens(2024)10.1371/journal.ppat.1012496

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3 citations

Morgan Chaunzwa, Derick M. Duell, Alejandra Marenco, William Goodwin, Rachel Dannay +24 more

Neuroinflammation associated with proviral DNA persists in the brain of virally suppressed people with HIV

Frontiers in Immunology(2025)10.3389/fimmu.2025.1570692

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11 citations

Janna Jamal Eddine, Jingling Zhou, Emily Chalmers, Emma Wanicek, Narin Osman +7 more

Contribution of intact viral genomes persisting in blood and tissues during ART to plasma viral rebound in SHIV-infected rhesus macaques

iScience(2025)10.1016/j.isci.2025.111998

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7 citations

Corentin Richard, Amélie Pagliuzza, Caroline Dufour, Audrée Lemieux, Natasha M. Clark +10 more

Identification of initial sites of SIV rebound after treatment cessation

Research Square(2025)10.21203/rs.3.rs-6814218/v1

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2 citations

Brandon F. Keele, Afam A. Okoye, Taina T. Immonen, Benjamin Varco-Merth, Derick M. Duell +23 more

Impact of Dolutegravir plus Lamivudine as First-Line Antiretroviral Treatment on HIV-1 Reservoir and Inflammatory Markers in Peripheral Blood

UNC Libraries(2025)10.17615/r0t8-mm19

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0 citations

Yovaninna Alarcón‐Soto, Maria C. García-Guerrero, Lucía Bailón, Àngel Rivero, Beatriz Mothe +9 more

Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

Cell(2020)10.1016/j.cell.2020.11.007

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212 citations

María Pino, Arun K. Boddapati, Elise G. Viox, Carly E. Starke, Amit A. Upadhyay +40 more