Edward J. Lesnefsky

Also affiliated with Virginia Commonwealth University Medical Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 19 papers. Top paper: “Endoplasmic reticulum stress-mediated mitochondrial dysfunction in aged hearts”.

Endoplasmic reticulum stress-mediated mitochondrial dysfunction in aged hearts

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2020)10.1016/j.bbadis.2020.165899

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0DataRank · unranked

78 citations

Arun Samidurai, Jeremy Thompson, Ying Hu, Anindita Das, Belinda Willard +2 more

Endoplasmic reticulum stress-induced complex I defect: Central role of calcium overload

Archives of Biochemistry and Biophysics(2020)10.1016/j.abb.2020.108299

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0DataRank · unranked

51 citations

Jeremy Thompson, Ying Hu, John M. Hollander, Edward J. Lesnefsky, Qun Chen +1 more

Metformin and myocardial ischemia and reperfusion injury: Moving toward “prime time” human use?

Translational research(2020)10.1016/j.trsl.2020.10.006

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0DataRank · unranked

8 citations

Edward J. Lesnefsky, Qun Chen

Evaluating the Bioenergetics Health Index Ratio in Leigh Syndrome Fibroblasts to Understand Disease Severity

International Journal of Molecular Sciences(2021)10.3390/ijms221910344

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0DataRank · unranked

16 citations

Joseph Dean, Qun Chen, Vedant Thorat, Yimin Huang, Thomas LaFramboise +3 more

NLRP3-mediated inflammation in cardio-oncology: sterile yet harmful

Translational research(2022)10.1016/j.trsl.2022.08.004

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0DataRank · unranked

32 citations

Eleonora Mezzaroma, Stefano Toldo, Giselle C. Meléndez, R. Lee Franco, Edward J. Lesnefsky +4 more

The Cardiac Dysfunction Caused by Metabolic Alterations in Alzheimer's Disease

Frontiers in Cardiovascular Medicine(2022)10.3389/fcvm.2022.850538

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0DataRank · unranked

24 citations

Tran Ngoc Van Le, Julia Fedorova, Yi Yang, Meredith Krause‐Hauch, Kayla Davitt +6 more

Calpain-mediated protein targets in cardiac mitochondria following ischemia–reperfusion

Scientific Reports(2022)10.1038/s41598-021-03947-9

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0DataRank · unranked

19 citations

Jeremy Thompson, Ying Hu, Edward J. Lesnefsky, Belinda Willard, Qun Chen +1 more

The mitochondrial electron transport chain contributes to calpain 1 activation during ischemia-reperfusion

Biochemical and Biophysical Research Communications(2022)10.1016/j.bbrc.2022.04.117

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0DataRank · unranked

12 citations

Jeremy Thompson, Ying Hu, Edward J. Lesnefsky, Qun Chen

Endoplasmic reticulum stress and mitochondrial dysfunction during aging: Role of sphingolipids

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids(2023)10.1016/j.bbalip.2023.159366

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0DataRank · unranked

21 citations

Anna Kovilakath, Jeremy C. Allegood, Jeremy Thompson, Ying Hu, L. Ashley Cowart +2 more

Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease

Journal of Lipid Research(2023)10.1016/j.jlr.2023.100363

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0DataRank · unranked

16 citations

Daniel Rodrı́guez-Agudo, Mitsuyoshi Suzuki, Yamato Muto, Saeko Hirai, Yaping Wang +12 more

Induced pluripotent stem cells derived from patients carrying mitochondrial mutations exhibit altered bioenergetics and aberrant differentiation potential

Stem Cell Research & Therapy(2023)10.1186/s13287-023-03546-7

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0DataRank · unranked

13 citations

Kelly M. Scheulin, Christopher M. Littlejohn, Joshua Stabach, Bibhuti Ballav Saikia, Vedant Thorat +7 more

Acute, High Dose Metformin Therapy at Reperfusion Decreases Infarct Size in the High-Risk Aging Heart

Aging and Disease(2023)10.14336/ad.2023.0205

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0DataRank · unranked

8 citations

Meredith Krause‐Hauch, Hao Wang, Mohammad Kasim Fatmi, Zehui Li, Qun Chen +4 more

New Insight Into Cardioprotection From Anthracyclines

JACC CardioOncology(2023)10.1016/j.jaccao.2023.01.008

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0DataRank · unranked

2 citations

Giselle C. Meléndez, Edward J. Lesnefsky, Qun Chen

Administration of metformin rescues age-related vulnerability to ischemic insults through mitochondrial energy metabolism

Biochemical and Biophysical Research Communications(2023)10.1016/j.bbrc.2023.04.004

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0DataRank · unranked

5 citations

Hao Wang, Linda Ines Zoungrana, Adewale Segun James, Lily Slotabec, Steven Didik +5 more

SPTLC3 Is Essential for Complex I Activity and Contributes to Ischemic Cardiomyopathy

Circulation(2024)10.1161/circulationaha.123.066879

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0DataRank · unranked

18 citations

Adolfo G Mauro, Yolander Valentine, Frank J. Raucci, Maryam Jamil, C. Ross Carter +23 more

Acute endoplasmic reticulum stress‐induced mitochondria respiratory chain damage: The role of activated calpains

The FASEB Journal(2024)10.1096/fj.202301158rr

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0DataRank · unranked

8 citations

Ling Li, Arun Samidurai, Jeremy Thompson, Ying Hu, Belinda Willard +2 more

Sphingosine kinase 2 (SphK2) depletion alters redox metabolism and enhances inflammation in a diet-induced MASH mouse model

Hepatology Communications(2024)10.1097/hc9.0000000000000570

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0DataRank · unranked

5 citations

Derrick Zhao, Lianyong Su, Marissa K. Lipp, Cameron Toler, Michael O. Idowu +11 more

Sphingosine-1-phosphate activates ICl,swell in ventricular myocytes via mitochondrial reactive oxygen production

Journal of Molecular and Cellular Cardiology(2025)10.1016/j.yjmcc.2025.11.009

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0DataRank · unranked

2 citations

Adolfo G Mauro, Edward J. Lesnefsky, Clive M. Baumgarten, Frank J. Raucci

Calpain activation disrupts ER-Phagy and leads to mitochondrial damage in hearts treated with isoproterenol

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2025)10.1016/j.bbadis.2025.168127

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0DataRank · unranked

0 citations

Ling Li, Jeremy Thompson, Ying Hu, Belinda Willard, Edward J. Lesnefsky +1 more