Xi Chen

The University of Texas MD Anderson Cancer Center

Also affiliated with University of Miami, Baylor College of Medicine, University of Miami Health System, Sylvester Comprehensive Cancer Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.741Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

MIAMI-AD (Methylation in Aging and Methylation in AD): an integrative knowledgebase that facilitates explorations of DNA methylation across sex, aging, and Alzheimer’s disease

Database(2024)10.1093/database/baae061

Top 56%

0.292DataRank

Top 56%6 citations

Deirdre O’Shea, Hanchen Huang, Wei Zhang, Juan I. Young, Xi Chen +5 more

Papers

Driven by 35 papers — median percentile 39. Top paper: “Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy”.

Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy

Cell(2020)10.1016/j.cell.2020.10.036

N/A

8.1DataRank · unranked

565 citations

Eric J. Jaehnig, Shankha Satpathy, Lili M. Blumenberg, Alla Y. Karpova, Meenakshi Anurag +85 more

Copper-dependent autophagic degradation of GPX4 drives ferroptosis

Autophagy(2023)10.1080/15548627.2023.2165323

N/A

0.960DataRank · unranked

600 citations

Yan Ding, Xi Chen, Xi Chen, Xiaofen Li, Rui Kang +6 more

Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer

Cell(2023)10.1016/j.cell.2023.07.004

N/A

0.680DataRank · unranked

92 citations

Jacob J. Kennedy, Richard G. Ivey, Oscar Murillo, Noshad Hosseini, Xiaoyu Song +42 more

Triptolide and its prodrug Minnelide target high-risk MYC-amplified medulloblastoma in preclinical models

Journal of Clinical Investigation(2024)10.1172/jci171136

N/A

0.464DataRank · unranked

21 citations

April Salvador, Robert K. Suter, Marzena Swiderska‐Syn, Isabel Palomo-Caturla, Valentin Kliebe +23 more

MIAMI-AD (Methylation in Aging and Methylation in AD): an integrative knowledgebase that facilitates explorations of DNA methylation across sex, aging, and Alzheimer’s disease

Database(2024)10.1093/database/baae061

Top 56%

0.292DataRank

Top 56%6 citations

Deirdre O’Shea, Hanchen Huang, Wei Zhang, Juan I. Young, Xi Chen +5 more

MIAMI-AD (Methylation in Aging and Methylation in AD): an integrative knowledgebase that facilitates explorations of DNA methylation across sex, aging, and Alzheimer’s disease

medRxiv(2023)10.1101/2023.12.04.23299412

Top 61%

0.241DataRank

Top 61%4 citations

Deirdre O’Shea, Hanchen Huang, Wei Zhang, Juan I. Young, Xi Chen +5 more

Cross-tissue meta-analysis of blood and brain epigenome-wide association studies in Alzheimer’s disease

medRxiv(2022)10.1101/2022.04.11.22273748

Top 65%

0.208DataRank

Top 65%3 citations

Juan I. Young, Lanyu Zhang, Lissette Gomez, Michael A. Schmidt, Achintya Varma +4 more

MethReg: estimating the regulatory potential of DNA methylation in gene transcription

Nucleic Acids Research(2022)10.1093/nar/gkac030

N/A

0DataRank · unranked

30 citations

Juan I. Young, Eden R. Martin, Xi Chen, Lily Wang, Tiago C. Silva

Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-21-0925

N/A

0DataRank · unranked

27 citations

Wen Zhang, Yanqi Xie, Xi Chen, Emma E. Olmstead, Mengqiang Lian +8 more

Distinct CSF biomarker-associated DNA methylation in Alzheimer’s disease and cognitively normal subjects

Alzheimer s Research & Therapy(2023)10.1186/s13195-023-01216-7

N/A

0DataRank · unranked

36 citations

Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma +4 more

ΔNp63 Regulates Homeostasis, Stemness, and Suppression of Inflammation in the Adult Epidermis

Journal of Investigative Dermatology(2023)10.1016/j.jid.2023.07.005

N/A

0DataRank · unranked

15 citations

Xi Chen, Ozge Somuncu, Jinyu Li, Alexander N. Joukov, Jiang Chen +2 more

Distinct CSF biomarker-associated DNA methylation in Alzheimer's disease and cognitively normal subjects

Research Square(2023)10.21203/rs.3.rs-2391364/v1

N/A

0DataRank · unranked

3 citations

Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma +4 more

Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC BeadChip microarrays

Research Square(2023)10.21203/rs.3.rs-3068938/v2

N/A

0DataRank · unranked

1 citations

Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma +5 more

Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC BeadChip microarrays for dementia research

Research Square(2023)10.21203/rs.3.rs-3068938/v1

N/A

0DataRank · unranked

0 citations

Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma +5 more

Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC v1.0 BeadChip microarrays

Epigenetics(2024)10.1080/15592294.2024.2333660

N/A

0DataRank · unranked

13 citations

Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma +5 more

Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer

Cell(2024)10.1016/j.cell.2024.01.016

N/A

0DataRank · unranked

11 citations

Jacob J. Kennedy, Richard G. Ivey, Oscar Murillo, Noshad Hosseini, Xiaoyu Song +42 more

Ensemble methods of rank-based trees for single sample classification with gene expression profiles

Journal of Translational Medicine(2024)10.1186/s12967-024-04940-2

N/A

0DataRank · unranked

9 citations

Ruijie Yin, Xi Chen, Min Lü

Discovery and validation of a 10-gene predictive signature for response to adjuvant chemotherapy in stage II and III colon cancer

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101661

N/A

0DataRank · unranked

8 citations

Peng Xia, Jie Li, Keeli B. Lewis, Kristen K. Ciombor, Lily Wang +4 more

Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer

Cancer Research(2024)10.1158/0008-5472.can-24-0133

N/A

0DataRank · unranked

4 citations

Clara I. Troccoli, Beatriz Mateo-Victoriano, Laura Misiara Lincheta, Erin A. Jackson, Ping Shu +14 more

Enhancing Chemotherapy Response Prediction via Matched Colorectal Tumor-Organoid Gene Expression Analysis and Network-Based Biomarker Selection

medRxiv(2024)10.1101/2024.01.24.24301749

N/A

0DataRank · unranked

2 citations

Chao Wu, Hanchen Huang, Paulina Bleu, Wini Zambare, Janet Alvarez +6 more

Discovery of Oncogenic Mediator Genes in Rectal Cancer Chemotherapy Response using Gene Expression Data from Matched Tumor and Patient-Derived Organoid

medRxiv(2024)10.1101/2024.01.29.24301906

N/A

0DataRank · unranked

2 citations

Chao Wu, Antonio Colaprico, Paulina Bleu, Wini Zambare, Janet Alvarez +8 more

Blood DNA Methylation Signature for Incident Dementia: Evidence from Longitudinal Cohorts

medRxiv(2024)10.1101/2024.11.03.24316667

N/A

0DataRank · unranked

1 citations

Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Brian W. Kunkle +4 more

DNA methylation signature of a lifestyle-based resilience index for cognitive health

Alzheimer s Research & Therapy(2025)10.1186/s13195-025-01733-7

N/A

0DataRank · unranked

7 citations

David Lukacsovich, Juan I. Young, Lissette Gomez, Michael A. Schmidt, Eden R. Martin +6 more

Blood DNA methylation signature for incident dementia: Evidence from longitudinal cohorts

Alzheimer s & Dementia(2025)10.1002/alz.14496

N/A

0DataRank · unranked

11 citations

Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Brian W. Kunkle +4 more

Enhancing chemotherapy response prediction via matched colorectal tumor-organoid gene expression analysis and network-based biomarker selection

Translational Oncology(2025)10.1016/j.tranon.2024.102238

N/A

0DataRank · unranked

4 citations

Chao Wu, Hanchen Huang, Paulina Bleu, Wini Zambare, Janet Alvarez +6 more

Eos plays a critical role in Treg homeostasis and modulates the function of recirculating thymic Tregs in the control of Treg development

Cell Reports(2025)10.1016/j.celrep.2025.116838

N/A

0DataRank · unranked

1 citations

Angela M. Thornton, Shalini Tanwar, Patricia R. Korty, Alexandria Wells, Elisha Segrist +23 more

An integrative multiomics random forest framework for robust biomarker discovery

GigaScience(2025)10.1093/gigascience/giaf148

N/A

0DataRank · unranked

1 citations

Hanchen Huang, Lily Wang, Brian D. Lehmann, Xi Chen, Wei Zhang

Integrating Tumor and Organoid DNA Methylation Profiles Reveals Robust Predictors of Chemotherapy Response in Rectal Cancer

medRxiv(2025)10.1101/2025.02.28.25322951

N/A

0DataRank · unranked

0 citations

Wini Zambare, Chao Wu, Hanchen Huang, Wei Zhang, Min Jung Kim +8 more

DNA methylation signatures of Life’s Essential 8 and their implications for dementia

Alzheimer s Research & Therapy(2025)10.1186/s13195-025-01903-7

N/A

0DataRank · unranked

0 citations

Liyong Wang, Juan I. Young, Wei Zhang, Lissette Gomez, Michael A. Schmidt +13 more

Multi-omics analysis identifies therapeutic vulnerabilities in triple-negative breast cancer subtypes

Nature Communications(2021)10.1038/s41467-021-26502-6

N/A

0DataRank · unranked

263 citations

Antonio Colaprico, Tiago C. Silva, Jianjiao Chen, Hanbing An, Yuguang Ban +10 more

A SMAD4 ‐modulated gene profile predicts disease‐free survival in stage II and III colorectal cancer

Cancer Reports(2021)10.1002/cnr2.1423

N/A

0DataRank · unranked

29 citations

Chao Wu, Michael R. Marco, Hyun Sung Park, Zeda Zhang, Bing Zhang +5 more

PathwayMultiomics: An R Package for Efficient Integrative Analysis of Multi-Omics Datasets With Matched or Un-matched Samples

Frontiers in Genetics(2021)10.3389/fgene.2021.783713

N/A

0DataRank · unranked

17 citations

Antonio Colaprico, Tiago C. Silva, Xi Chen, Lily Wang, Gabriel Odom

LR Hunting: A Random Forest Based Cell–Cell Interaction Discovery Method for Single-Cell Gene Expression Data

Frontiers in Genetics(2021)10.3389/fgene.2021.708835

N/A

0DataRank · unranked

17 citations

Yifan Sha, Tiago C. Silva, Antonio Colaprico, Xiaodian Sun, Yuguang Ban +4 more

Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer’s disease

Nature Communications(2022)10.1038/s41467-022-32475-x

N/A

0DataRank · unranked

58 citations

Juan I. Young, Lanyu Zhang, Lissette Gomez, Michael A. Schmidt, Achintya Varma +4 more

Distinct sex-specific DNA methylation differences in Alzheimer’s disease

Alzheimer s Research & Therapy(2022)10.1186/s13195-022-01070-z

N/A

0DataRank · unranked

33 citations

Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, Achintya Varma +4 more

Xi Chen

Indexed papers

Top data-sharing exemplar

Papers