Bruno Melillo

Also affiliated with Scripps Research Institute, Scripps Institution of Oceanography, Scripps (United States)

Immunology and MicrobiologyChemistryBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 34 papers. Top paper: “Stabilizing the HIV-1 Envelope Glycoprotein State 2A Conformation”.

Stabilizing the HIV-1 Envelope Glycoprotein State 2A Conformation

Journal of Virology(2020)10.1128/jvi.01620-20

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12 citations

Shang Yu Gong, William D. Tolbert, Shilei Ding, Dung N. Nguyen, Jonathan Richard +6 more

Elicitation of Cluster A and Co-Receptor Binding Site Antibodies Are Required to Eliminate HIV-1 Infected Cells

Microorganisms(2020)10.3390/microorganisms8050710

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25 citations

Jérémie Prévost, Gabrielle Gendron‐Lepage, Bruno Melillo, Junhua Chen, Amos B. Smith +3 more

Cryo-EM Structures of HIV-1 trimer bound to CD4-mimetics M48U1 and BNM-III-170 adopt a CD4-bound open conformation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.21.261974

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1 citations

Christopher O. Barnes, Sharon Kirk, Bruno Melillo, Amos B. Smith, Pamela J. Björkman +1 more

Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation

Nature Communications(2021)10.1038/s41467-021-21816-x

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45 citations

Christopher O. Barnes, Sharon Kirk, Bruno Melillo, Amos B. Smith, Pamela J. Björkman +1 more

LPCAT3 Inhibitors Remodel the Polyunsaturated Phospholipid Content of Human Cells and Protect from Ferroptosis

ACS Chemical Biology(2022)10.1021/acschembio.2c00317

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151 citations

Taka-Aki Ichu, Natalia Milosevich, Bruno Melillo, Michael A. Schafroth, Yuka Otsuka +4 more

Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1

Journal of the American Chemical Society(2022)10.1021/jacs.2c08964

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133 citations

David Remillard, Ekaterina V. Vinogradova, Minoru Yokoyama, Sofia Banchenko, David Schwefel +5 more

Stereochemical diversity as a source of discovery in chemical biology

Current Research in Chemical Biology(2022)10.1016/j.crchbi.2022.100028

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81 citations

Nathalie Ropek, Bruno Melillo, Stuart L. Schreiber, Benjamin F. Cravatt, Ekaterina V. Vinogradova +1 more

Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2208457119

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78 citations

Elisa Merlini, Carlos Guijas, Kristen E. DeMeester, Evert Njomen, Ellen M. Kozina +9 more

Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase

Nature Communications(2022)10.1038/s41467-022-28108-y

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26 citations

Bruno Melillo, Payal Mittal, Manmohan Sharma, Amit Sharma, Yong Fu +8 more

Proteomic discovery of chemical probes that perturb protein complexes in human cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.12.520090

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11 citations

Jarrett R. Remsberg, Martin G. Jaeger, Katherine Rothamel, Hsuan-Lin Her, Kristen E. DeMeester +30 more

Proteomic discovery of chemical probes that perturb protein complexes in human cells

Molecular Cell(2023)10.1016/j.molcel.2023.03.026

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94 citations

Jarrett R. Remsberg, Martin G. Jaeger, Katherine Rothamel, Hsuan-Lin Her, Kristen E. DeMeester +30 more

Assigning functionality to cysteines by base editing of cancer dependency genes

Nature Chemical Biology(2023)10.1038/s41589-023-01428-w

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63 citations

Tiantai Ma, Jarrett R. Remsberg, Sang Joon Won, Kristen E. DeMeester, Evert Njomen +11 more

Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2

Angewandte Chemie International Edition(2023)10.1002/anie.202311924

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58 citations

Jan G. Felber, Zhongyu Zou, Evert Njomen, Jarrett R. Remsberg, Daisuke Ogasawara +7 more

Genetic crosses within and between species of Cryptosporidium

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2313210120

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43 citations

Ian S. Cohn, Rodrigo P. Baptista, Guoqin Xia, Bruno Melillo, Fiifi Agyabeng‐Dadzie +3 more

Comprehensive Mapping of Electrophilic Small Molecule-Protein Interactions in Human Cells

ChemRxiv(2023)10.26434/chemrxiv-2023-s446n

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13 citations

Evert Njomen, Rachel Hayward, Kristen E. DeMeester, Daisuke Ogasawara, Melissa M. Dix +6 more

Covalent Targeting of Splicing in T Cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.18.572199

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5 citations

Hiroyuki Kojima, Nathalie Ropek, Charles David Warren, Tiffany L. Zhang, Simon J. Hogg +9 more

Genetic crosses within and between species of Cryptosporidium

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.04.551960

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3 citations

Ian S. Cohn, Rodrigo P. Baptista, Guoqin Xia, Bruno Melillo, Fiifi Agyabeng‐Dadzie +3 more

Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2

Angewandte Chemie(2023)10.1002/ange.202311924

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0DataRank · unranked

0 citations

Jan G. Felber, Zhongyu Zou, Evert Njomen, Jarrett R. Remsberg, Daisuke Ogasawara +7 more

Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells

Nature Chemistry(2024)10.1038/s41557-024-01601-1

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55 citations

Rachel E. Hayward, Kristen E. DeMeester, Daisuke Ogasawara, Melissa M. Dix, Tracey Nguyen +6 more

Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders

Journal of the American Chemical Society(2024)10.1021/jacs.3c13448

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40 citations

Jarrett R. Remsberg, Haoxin Li, Evert Njomen, Kristen E. DeMeester, Yongfeng Tao +9 more

Redirecting the pioneering function of FOXA1 with covalent small molecules

Molecular Cell(2024)10.1016/j.molcel.2024.09.024

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36 citations

Yuxiang Zhang, Christopher J. Reinhardt, Lauren M Hargis, Nicole S. MacRae, Kristen E. DeMeester +6 more

Chemical tools to expand the ligandable proteome: Diversity-oriented synthesis-based photoreactive stereoprobes

Cell chemical biology(2024)10.1016/j.chembiol.2024.10.005

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26 citations

David B. Konrad, Zher Yin Tan, Kimberly L. Carey, Jessica Y. Luo, Sang Joon Won +9 more

Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance

Science(2024)10.1126/science.adk9893

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26 citations

Karla P. Godinez‐Macias, Daisy Chen, John Okombo, Vandana Thathy, Xiu Cheng +43 more

Covalent targeting of splicing in T cells

Cell chemical biology(2024)10.1016/j.chembiol.2024.10.010

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16 citations

Hiroyuki Kojima, Nathalie Ropek, Charles David Warren, Tiffany L. Zhang, Simon J. Hogg +10 more

Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly

ACS Chemical Biology(2024)10.1021/acschembio.3c00330

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14 citations

Jie Sun, Kayla Nutsch, Jessica D. Rosarda, Thu Nguyen, Chloris Li-Ma +9 more

SF3B1 thermostability as an assay for splicing inhibitor interactions

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.108135

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5 citations

Guddeti Chandrashekar Reddy, Bruno Melillo, Benjamin F. Cravatt, Arun K. Ghosh, Melissa S. Jurica +1 more

Bicyclic Pyrrolidine Inhibitors of Toxoplasma gondii Phenylalanine t-RNA Synthetase with Antiparasitic Potency In Vitro and Brain Exposure

ACS Infectious Diseases(2024)10.1021/acsinfecdis.4c00170

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3 citations

Taher Uddin, Julien Borrel, Payal Mittal, Han Xie, Jochen Zoller +7 more

Redirecting the pioneering function of FOXA1 with covalent small molecules

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.21.586158

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0DataRank · unranked

10 citations

Yuxiang Zhang, Christopher J. Reinhardt, Nicole S. MacRae, Kristen E. DeMeester, Evert Njomen +6 more

Chemical tools to expand the ligandable proteome: diversity-oriented synthesis-based photoreactive stereoprobes

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.27.582206

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8 citations

David B. Konrad, Zher Yin Tan, Kimberly L. Carey, Jessica Y. Luo, Sang Joon Won +9 more

Simple, Enantiocontrolled Azetidine Library Synthesis via Strain Release Functionalization of 1-Azabicyclobutanes

ChemRxiv(2024)10.26434/chemrxiv-2024-cmvd4

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3 citations

Molhm Nassir, Hayden A. Sharma, Nathanyal J. Truax, Nicholas Raheja, Ty M. Thompson +5 more

Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.28.582607

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0DataRank · unranked

0 citations

Taher Uddin, Julien Borrel, Payal Mittal, Han Xie, Jochen Zoller +7 more

Enantiocontrolled Azetidine Library Synthesis via Strain-Release Functionalization of 1-Azabicyclobutanes

Journal of the American Chemical Society(2025)10.1021/jacs.5c07227

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18 citations

Molhm Nassir, Hayden A. Sharma, Nathanyal J. Truax, Nicholas Raheja, Ty M. Thompson +5 more

Proteomic Ligandability Maps of Phosphorus(V) Stereoprobes Identify Covalent TLCD1 Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.31.635883

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1 citations

Michael Bielecki, Meredith A. Holm, Ty M. Thompson, Yue Yin, Jacob B. Cravatt +9 more

A cold-inducible phospholipid—protein interaction in brown fat mitochondria optimizes thermogenic capacity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.15.654206

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1 citations

Marc J. Tol, Christian Rocha-Roa, Matthew J. Jellinek, Liujuan Cui, Aaron Bender +23 more