Fumihiko Urano

Also affiliated with Washington University in St. Louis

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 28 papers. Top paper: “Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice”.

Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice

Science Translational Medicine(2020)10.1126/scitranslmed.aax9106

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184 citations

Punn Augsornworawat, Leonardo Velazco-Cruz, Michelle H. Kim, Rie Asada, Nathaniel J. Hogrebe +4 more

Primary cilia control glucose homeostasis via islet paracrine interactions

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2001936117

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101 citations

Jung Hoon Cho, Hannah Conway, Michael R. DiGruccio, Xue Wen Ng, Henry F. Roseman +4 more

Neuroplastin Modulates Anti-inflammatory Effects of MANF

iScience(2020)10.1016/j.isci.2020.101810

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76 citations

Rie Asada, Kohsuke Kanekura, Ave Eesmaa, Maria Lindahl, Märt Saarma +2 more

A soluble endoplasmic reticulum factor as regenerative therapy for Wolfram syndrome

Laboratory Investigation(2020)10.1038/s41374-020-0436-1

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17 citations

Shuntaro Morikawa, Takuya Yagi, Damien Abreu, Simin Lu, Kohsuke Kanekura +3 more

Digenic Variants in the FGF21 Signaling Pathway Associated with Severe Insulin Resistance and Pseudoacromegaly

Journal of the Endocrine Society(2020)10.1210/jendso/bvaa138

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12 citations

Daniel Wegner, Jennifer Wambach, F. Sessions Cole, Fumihiko Urano, David M. Ornitz +1 more

Wolfram syndrome 1 gene regulates pathways maintaining beta-cell health and survival

Laboratory Investigation(2020)10.1038/s41374-020-0408-5

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45 citations

Rie Asada, John M.P. Revilla, Zeno Lavagnino, Kelly Kries, David W. Piston +2 more

Monogenic and syndromic diabetes due to endoplasmic reticulum stress

Journal of Diabetes and its Complications(2020)10.1016/j.jdiacomp.2020.107618

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35 citations

Damien Abreu, Janet B. McGill, Fumihiko Urano, Stephen Stone

A phase Ib/IIa clinical trial of dantrolene sodium in patients with Wolfram syndrome

JCI Insight(2021)10.1172/jci.insight.145188

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40 citations

Stephen Stone, Toni S. Pearson, Robert C. Bucelli, Ashley N. Simpson, Stacy Hurst +12 more

A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome

Cell Reports(2021)10.1016/j.celrep.2021.109040

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29 citations

Kathleen A. Trychta, Shyh‐Ming Yang, Susanne Bäck, Adam Yasgar, Emily S. Wires +21 more

Altered neuronal physiology, development, and function associated with a common chromosome 15 duplication involving CHRNA7

BMC Biology(2021)10.1186/s12915-021-01080-7

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19 citations

Ramachandran Prakasam, Dustin Baldridge, Paul Gontarz, Bo Zhang, Fumihiko Urano +7 more

Genotype-phenotype correlation analysis and therapeutic development using a patient stem cell-derived disease model of Wolfram syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.07.467657

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0 citations

Kristina G. Maxwell, Wenjuan Ye, Kelly Kries, Cris Brown, Punn Augsornworawat +12 more

Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2116505119

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59 citations

Yeawon Kim, Chuang Li, Junwoo Suh, Jothilingam Sivapackiam, Tássia Mangetti Gonçalves +6 more

Wolframin is a novel regulator of tau pathology and neurodegeneration

Acta Neuropathologica(2022)10.1007/s00401-022-02417-4

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42 citations

Diana Acosta, Liangping Li, Jiawen Liang, Yuzhou Chang, Cankun Wang +25 more

Multidimensional analysis and therapeutic development using patient iPSC–derived disease models of Wolfram syndrome

JCI Insight(2022)10.1172/jci.insight.156549

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30 citations

Kristina G. Maxwell, Wenjuan Ye, Kelly Kries, Cris Brown, Punn Augsornworawat +12 more

Loss of Function of WFS1 Causes ER Stress-Mediated Inflammation in Pancreatic Beta-Cells

Frontiers in Endocrinology(2022)10.3389/fendo.2022.849204

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33 citations

Lindsey Blacher, Chinyere Onwumere, Fumihiko Urano, Shuntaro Morikawa

Plasma Neurofilament Light Chain Levels Are Elevated in Children and Young Adults With Wolfram Syndrome

Frontiers in Neuroscience(2022)10.3389/fnins.2022.795317

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11 citations

Raveena Boodram, Courtney L. Sutphen, Heather M. Lugar, Brian A. Gordon, Bess A. Marshall +4 more

Anti-inflammatory effects of WFS1 in pancreatic β-cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.09.479773

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0 citations

Lindsey Blacher, Chinyere Onwumere, Fumihiko Urano, Shuntaro Morikawa

Palmitoylation couples insulin hypersecretion with β cell failure in diabetes

Cell Metabolism(2023)10.1016/j.cmet.2022.12.012

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65 citations

Sangeeta Adak, George D. Spyropoulos, Qiang Zhang, Feng Chu, Yin Li +13 more

MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice

Nature Communications(2023)10.1038/s41467-023-42154-0

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58 citations

Chuang Li, Chenjian Gu, Yili Fang, Eric Tycksen, Anuradhika Puri +14 more

GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models

Diabetologia(2023)10.1007/s00125-023-05905-8

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33 citations

Bahareh Rajaei, Chae Heeyoung, Bruno J. Santacreu, Sandra Marín‐Cañas, Paraskevi Salpea +20 more

Genotype and clinical characteristics of patients with Wolfram syndrome and WFS1-related disorders

Frontiers in Genetics(2023)10.3389/fgene.2023.1198171

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31 citations

Megha Verma, Nila Palaniappan, Emiko M. Pope, Sammie Lee, Lindsey Blacher +11 more

Cystic and Atrophic Kidneys, Atrophic Pancreas, Arcuate Uterus, and Diabetes Mellitus Associated With Deletion of HNF1β Gene

AACE Clinical Case Reports(2023)10.1016/j.aace.2023.06.003

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1 citations

Alberto Sobrero, Amy E. Riek, Janet B. McGill, Fumihiko Urano, Rachel L. Usala

Genotype and Clinical Characteristics of Patients with Wolfram Syndrome and WFS1-related Disorders

medRxiv(2023)10.1101/2023.02.15.23284904

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3 citations

Megha Verma, Nila Palaniappan, Emiko M. Pope, Sammie Lee, Lindsey Blacher +11 more

Dual Role of Neuroplastin in Pancreatic β Cells: Regulating Insulin Secretion and Promoting Islet Inflammation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.08.556759

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1 citations

Devynn Hummel, Fumihiko Urano, Rie Asada Kitamura

MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.10.523171

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0 citations

Chuang Li, Chenjian Gu, Eric Tycksen, Anuradhika Puri, Terri Pietka +14 more

Identification of unique cell type responses in pancreatic islets to stress

Nature Communications(2024)10.1038/s41467-024-49724-w

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44 citations

Matthew Ishahak, Punn Augsornworawat, Daniel Veronese-Paniagua, Kristina G. Maxwell, Leonardo Velazco-Cruz +7 more

Dual role of neuroplastin in pancreatic β cells: Regulating insulin secretion and promoting islet inflammation

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2411234121

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5 citations

Devynn Hummel, Alessandro Ustione, David W. Piston, Fumihiko Urano, Rie Asada Kitamura

Extracellular vesicle R-Ras is a potential biomarker for human peripheral artery disease

iScience(2025)10.1016/j.isci.2025.113859

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2 citations

Mohamed Zaghloul, Shahab Hafezi, Fumihiko Urano, M.A. Zayed, Clay F. Semenkovich +1 more