Xuexiang Han

Center for Excellence in Molecular Cell Science

Also affiliated with University of Chinese Academy of Sciences, University of Pennsylvania

Biochemistry, Genetics and Molecular BiologyEngineeringMaterials ScienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 24 papers. Top paper: “Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis”.

Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis

Nature Communications(2023)10.1038/s41467-022-35637-z

N/A

0.783DataRank · unranked

184 citations

Ningqiang Gong, Lulu Xue, Margaret M. Billingsley, Rakan El‐Mayta, Sarah J. Shepherd +4 more

Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment

Journal of the American Chemical Society(2022)10.1021/jacs.2c02706

N/A

0.777DataRank · unranked

177 citations

Ningqiang Gong, Sarah J. Shepherd, Xinhong Xiong, Xueyang Liao, Xuexiang Han +14 more

High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models

Nature Communications(2024)10.1038/s41467-024-45422-9

N/A

0.728DataRank · unranked

127 citations

Alex G. Hamilton, Gan Zhao, Zebin Xiao, Rakan El‐Mayta, Xuexiang Han +13 more

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia

Nature(2024)10.1038/s41586-024-08291-2

N/A

0.702DataRank · unranked

107 citations

Alex G. Hamilton, Hannah C. Safford, Hannah C. Geisler, Ajay S. Thatte, Rohan Palanki +10 more

Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy

Advanced Materials(2024)10.1002/adma.202313226

N/A

0.648DataRank · unranked

74 citations

Marshall S. Padilla, Ningqiang Gong, Margaret M. Billingsley, Xuexiang Han, Maria Merolle +12 more

In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity

Nature Materials(2023)10.1038/s41563-023-01646-6

N/A

0.631DataRank · unranked

66 citations

Xuexiang Han, Lulu Xue, Rakan El‐Mayta, Ann E. Metzloff, Margaret M. Billingsley +3 more

Small-molecule-mediated control of the anti-tumour activity and off-tumour toxicity of a supramolecular bispecific T cell engager

Nature Biomedical Engineering(2024)10.1038/s41551-023-01147-6

N/A

0.470DataRank · unranked

22 citations

Xuexiang Han, Lulu Xue, Margaret M. Billingsley, Xisha Huang, Rakan El‐Mayta +5 more

Solid tumor growth depends on an intricate equilibrium of malignant cell states

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.30.573100

N/A

0.208DataRank · unranked

3 citations

Olivera Grbovic-Huezo, Anupriya Singhal, Matilda Holm, Katherine Wu, Xuexiang Han +10 more

Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo

Nature Chemistry(2024)10.1038/s41557-024-01557-2

N/A

0DataRank · unranked

85 citations

Mohamad‐Gabriel Alameh, Ningqiang Gong, Lulu Xue, Majed Ghattas, Goutham Bojja +12 more

In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors

Nature Communications(2024)10.1038/s41467-024-45537-z

N/A

0DataRank · unranked

69 citations

Junchao Xu, Ying Xu, Mohamad‐Gabriel Alameh, Lulu Xue, Ningqiang Gong +9 more

Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery

Nature Materials(2024)10.1038/s41563-024-01961-6

N/A

0DataRank · unranked

60 citations

Wenqun Zhong, Mohamad‐Gabriel Alameh, Xuexiang Han, Lulu Xue, Rakan El‐Mayta +15 more

Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering

Advanced Functional Materials(2024)10.1002/adfm.202312038

N/A

0DataRank · unranked

47 citations

Alex G. Hamilton, Margaret M. Billingsley, Jacqueline J. Li, Ajay S. Thatte, Xuexiang Han +7 more

TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue

Science Translational Medicine(2024)10.1126/scitranslmed.adg6229

N/A

0DataRank · unranked

43 citations

Lulu Xue, Aaron I. Weiner, Ningqiang Gong, Stephanie Adams‐Tzivelekidis, Joanna Wong +16 more

Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering

Nature Communications(2025)10.1038/s41467-024-55137-6

N/A

0DataRank · unranked

50 citations

Kaitlin Mrksich, Yiming Wang, Rebecca M. Haley, Jacqueline J. Li, Emily L. Han +16 more

Multiarm-Assisted Design of Dendron-like Degradable Ionizable Lipids Facilitates Systemic mRNA Delivery to the Spleen

Journal of the American Chemical Society(2025)10.1021/jacs.4c10265

N/A

0DataRank · unranked

34 citations

Xinhong Xiong, Gan Zhao, William A. Molina Arocho, Rohan Palanki, Zebin Xiao +14 more

An ionizable lipid toolbox for RNA delivery

Nature Communications(2021)10.1038/s41467-021-27493-0

N/A

0DataRank · unranked

594 citations

Hanwen Zhang, Kamila Butowska, Kelsey L. Swingle, Mohamad‐Gabriel Alameh, Drew Weissman +2 more

Circular RNA lipid nanoparticle vaccine against SARS-CoV-2

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2505718122

N/A

0DataRank · unranked

9 citations

Alex G. Hamilton, Xuexiang Han, Kuo‐Chieh Liao, Hannah C. Safford, Ajay S. Thatte +6 more

Nanotechnology-based strategies against SARS-CoV-2 variants

Nature Nanotechnology(2022)10.1038/s41565-022-01174-5

N/A

0DataRank · unranked

141 citations

Edo Kon, Xuexiang Han, Xingcai Zhang, Na Kong, Michael J. Mitchell +3 more

Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy

Acta Pharmaceutica Sinica B(2022)10.1016/j.apsb.2022.07.011

N/A

0DataRank · unranked

79 citations

Xuexiang Han, Ningqiang Gong, Rakan El‐Mayta, Rebecca M. Haley, Lulu Xue +5 more

Rational design of anti‐inflammatory lipid nanoparticles for mRNA delivery

Journal of Biomedical Materials Research Part A(2022)10.1002/jbm.a.37356

N/A

0DataRank · unranked

74 citations

Xuexiang Han, Mohamad‐Gabriel Alameh, Sarah J. Shepherd, Marshall S. Padilla, Lulu Xue +4 more

Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines

Nature Nanotechnology(2023)10.1038/s41565-023-01404-4

N/A

0DataRank · unranked

237 citations

Mohamad‐Gabriel Alameh, Kamila Butowska, James J. Knox, Kendall A. Lundgreen, Majed Ghattas +11 more

Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2303567120

N/A

0DataRank · unranked

125 citations

Xuexiang Han, Alvin J. Mukalel, Rakan El‐Mayta, Ajay S. Thatte, Jingyu Wu +8 more

Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity

Cell Reports(2023)10.1016/j.celrep.2023.113224

N/A

0DataRank · unranked

78 citations

Youtao Lu, Xuexiang Han, Jingbo Yang, Zhiyuan Qin, Wei Zhang +20 more

Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery

Nature Nanotechnology(2024)10.1038/s41565-024-01747-6

N/A

0DataRank · unranked

92 citations

Gan Zhao, Ningqiang Gong, Xuexiang Han, Sarah J. Shepherd, Xinhong Xiong +20 more