John S. Witte

Biochemistry, Genetics and Molecular BiologyMathematics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

4.9Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts

Nature Communications(2020)10.1038/s41467-020-18246-6

Top 4%

4.9DataRank

Top 4%313 citations

Rebecca E. Graff, Linda Kachuri, Khanh K. Thai, Stacey Alexeeff, Maruta A. Blatchins +14 more

Papers

Driven by 57 papers — median percentile 0. Top paper: “Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction”.

Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction

Nature Communications(2020)10.1038/s41467-020-19600-4

N/A

6.1DataRank · unranked

202 citations

Rebecca E. Graff, Karl Smith-Byrne, Travis J. Meyers, Sara R. Rashkin, Elad Ziv +3 more

Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts

Nature Communications(2020)10.1038/s41467-020-18246-6

Top 4%

4.9DataRank

Top 4%313 citations

Rebecca E. Graff, Linda Kachuri, Khanh K. Thai, Stacey Alexeeff, Maruta A. Blatchins +14 more

Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer

Nature Genetics(2022)10.1038/s41588-022-01115-x

N/A

2.1DataRank · unranked

123 citations

Younghun Han, Yafang Li, Jun Xia, Erping Long, Jiyeon Choi +80 more

A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry

Blood Advances(2020)10.1182/bloodadvances.2019000491

N/A

1.1DataRank · unranked

31 citations

Niels Weinhold, Gregory Song, Kristin A. Rand, David Van Den Berg, Amie E. Hwang +65 more

The PRIMED Consortium: Reducing disparities in polygenic risk assessment

The American Journal of Human Genetics(2024)10.1016/j.ajhg.2024.10.010

N/A

0.893DataRank · unranked

37 citations

Matthew P. Conomos, Sarah C. Nelson, Sally N. Adebamowo, Ananyo Choudhury, David V. Conti +90 more

Principles and methods for transferring polygenic risk scores across global populations

Nature Reviews Genetics(2023)10.1038/s41576-023-00637-2

N/A

0.869DataRank · unranked

328 citations

Nilanjan Chatterjee, Jibril Hirbo, Daniel J. Schaid, Iman K. Martin, Iftikhar J. Kullo +12 more

Genetic determinants of blood-cell traits influence susceptibility to childhood acute lymphoblastic leukemia

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.08.004

N/A

0.659DataRank · unranked

80 citations

Soyoung Jeon, Andrew T. DeWan, Catherine Metayer, Xiaomei Ma, John S. Witte +4 more

Genetically adjusted PSA levels for prostate cancer screening

Nature Medicine(2023)10.1038/s41591-023-02277-9

N/A

0.650DataRank · unranked

75 citations

Thomas J. Hoffmann, Yu Jiang, Sonja I. Berndt, John P. Shelley, Kerry Schaffer +18 more

The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics

Molecular Cell(2024)10.1016/j.molcel.2024.04.008

N/A

0.533DataRank · unranked

34 citations

Christian B. Macdonald, Darko Mitrovic, Xujia Zhou, Megan L. Koleske, Jia Yang +10 more

Genetic factors associated with prostate cancer conversion from active surveillance to treatment

Human Genetics and Genomics Advances(2021)10.1016/j.xhgg.2021.100070

N/A

0.477DataRank · unranked

23 citations

Travis J. Meyers, Adaeze A. Emeka, Lauren Folgosa Cooley, Phillip R. Cooper, Nicola Lancki +92 more

Polygenic Modeling of Genome-Wide Association Studies: An Application to Prostate and Breast Cancer

OMICS: A Journal of Integrative Biology(2011)10.1089/omi.2010.0090

N/A

0.464DataRank · unranked

21 citations

Thomas J. Hoffmann, John S. Witte

Cancer systems epidemiology: Overcoming misconceptions and integrating systems approaches into cancer research

PLoS Medicine(2022)10.1371/journal.pmed.1004027

N/A

0.434DataRank · unranked

17 citations

Nicolaas P. Pronk, Christopher I. Amos, John S. Witte, Patrick T. Wedlock, Sarah M. Bartsch +2 more

Cross-Cancer Evaluation of Polygenic Risk Scores for 17 Cancer Types in Two Large Cohorts

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.18.911578

N/A

0.425DataRank · unranked

16 citations

Taylor B. Cavazos, Khanh K. Thai, Linda Kachuri, Sara R. Rashkin, Joshua Hoffman +16 more

A genome‐wide association study of obstructive heart defects among participants in the National Birth Defects Prevention Study

American Journal of Medical Genetics Part A(2022)10.1002/ajmg.a.62759

N/A

0.417DataRank · unranked

9 citations

Mario A. Cleves, Gary M. Shaw, Wendy N. Nembhard, Eirini Nestoridi, Mary M. Jenkins +11 more

Genetic Factors Associated with Prostate Cancer Conversion from Active Surveillance to Treatment

medRxiv(2021)10.1101/2021.08.30.21262305

N/A

0.406DataRank · unranked

14 citations

Travis J. Meyers, Adaeze A. Emeka, Lauren Folgosa Cooley, Phillip R. Cooper, Nicola Lancki +92 more

Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups

Nature Genetics(2025)10.1038/s41588-024-02068-z

N/A

0.385DataRank · unranked

12 citations

Rebecca E. Graff, Ravi Madduri, Alex A Rodriguez, Clinton L. Cario, Kun-Jiang Feng +44 more

Development and testing of a polygenic risk score for breast cancer aggressiveness

npj Precision Oncology(2023)10.1038/s41698-023-00382-z

N/A

0.373DataRank · unranked

11 citations

Jacquelyn Roger, Christina Yau, Denise M. Wolf, Gillian L. Hirst, Lamorna Brown Swigart +18 more

Transcriptome-wide association analysis identifies candidate susceptibility genes for prostate-specific antigen levels in men without prostate cancer

Human Genetics and Genomics Advances(2024)10.1016/j.xhgg.2024.100315

N/A

0.269DataRank · unranked

5 citations

Ruocheng Dong, Linda Kachuri, Thomas J. Hoffmann, Yu Jiang, Sonja I. Berndt +19 more

Genetic analysis of lung cancer reveals novel susceptibility loci and germline impact on somatic mutation burden

medRxiv(2021)10.1101/2021.04.26.21254132

N/A

0.194DataRank · unranked

2 citations

Joshua Atkins, Ricardo Cortez Cardoso Penha, Karl Smith-Byrne, Valérie Gaborieau, Catherine Voegele +28 more

Development and testing of a polygenic risk score for breast cancer aggressiveness

medRxiv(2022)10.1101/2022.08.26.22278957

N/A

0.165DataRank · unranked

2 citations

Jacquelyn Roger, Christina Yau, Denise M. Wolf, Gillian L. Hirst, Lamorna Brown Swigart +18 more

Genetic Determinants of Blood Cell Traits Influence Susceptibility to Childhood Acute Lymphoblastic Leukemia

medRxiv(2021)10.1101/2021.04.17.21255679

N/A

0DataRank · unranked

3 citations

Soyoung Jeon, Andrew T. DeWan, Catherine Metayer, Xiaomei Ma, John S. Witte +4 more

Genetic Analysis of Lung Cancer and the Germline Impact on Somatic Mutation Burden

JNCI Journal of the National Cancer Institute(2022)10.1093/jnci/djac087

N/A

0DataRank · unranked

26 citations

Joshua Atkins, Ricardo Cortez Cardoso Penha, Karl Smith-Byrne, Valérie Gaborieau, Catherine Voegele +28 more

Assessment of Genetic Susceptibility to Multiple Primary Cancers through Whole-Exome Sequencing in Two Large Multi-Ancestry Studies

medRxiv(2022)10.1101/2022.02.11.22270688

N/A

0DataRank · unranked

3 citations

Linda Kachuri, Rebecca E. Graff, Jovia L. Nierenberg, Khanh K. Thai, Stacey Alexeeff +10 more

Re-envisioning community genetics: community empowerment in preventive genomics

Journal of Community Genetics(2023)10.1007/s12687-023-00638-y

N/A

0DataRank · unranked

8 citations

Daphne Oluwaseun Martschenko, Annamaria Smitherman, Sheryl Michelson, Ting Pun, John S. Witte +9 more

A gene‐based association test of interactions for maternal–fetal genotypes identifies genes associated with nonsyndromic congenital heart defects

Genetic Epidemiology(2023)10.1002/gepi.22533

N/A

0DataRank · unranked

3 citations

Chen Lyu, Nianjun Liu, Wendy N. Nembhard, John S. Witte, Charlotte A. Hobbs +3 more

Clinical consequences of a genetic predisposition toward higher benign prostate-specific antigen levels

EBioMedicine(2023)10.1016/j.ebiom.2023.104838

N/A

0DataRank · unranked

1 citations

John P. Shelley, Kerry Schaffer, Jeffrey J. Tosoian, Minoo Bagheri, John S. Witte +3 more

The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.06.543963

N/A

0DataRank · unranked

7 citations

Christian B. Macdonald, Darko Mitrovic, Xujia Zhou, Megan L. Koleske, Jia Yang +10 more

Data from Validation of Genome-Wide Prostate Cancer Associations in Men of African Descent

(2023)10.1158/1055-9965.c.6514782.v1

Top 100%

0DataRank

Top 100%0 citations

Elaine Spangler, Stephen Gallagher, Christopher A. Haiman, Brian E. Henderson, William B. Isaacs +29 more

Data from Validation of Genome-Wide Prostate Cancer Associations in Men of African Descent

(2023)10.1158/1055-9965.c.6514782

Top 100%

0DataRank

Top 100%0 citations

Elaine Spangler, Stephen Gallagher, Christopher A. Haiman, Brian E. Henderson, William B. Isaacs +29 more

Data from A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

(2023)10.1158/0008-5472.c.6513064

Top 100%

0DataRank

Top 100%0 citations

Taylor B. Cavazos, Sara R. Rashkin, Clinton L. Cario, Rebecca E. Graff, Caroline G. Tai +21 more

Transcriptome-Wide Association Analysis Identifies Novel Candidate Susceptibility Genes for Prostate-Specific Antigen Levels in Men Without Prostate Cancer

medRxiv(2023)10.1101/2023.05.04.23289526

N/A

0DataRank · unranked

0 citations

Ruocheng Dong, Linda Kachuri, Thomas J. Hoffmann, Yu Jiang, Sonja I. Berndt +16 more

A genome-wide association study of obstructive heart defects among participants in the National Birth Defects Prevention Study

UNC Libraries(2024)10.17615/ph8v-yc50

N/A

0DataRank · unranked

0 citations

Mary M. Jenkins, Sara R. Rashkin, Paul A. Romitti, Andrew F. Olshan, Marilyn L. Browne +11 more

Investigating the Role of Neighborhood Socioeconomic Status and Germline Genetics on Prostate Cancer Risk

medRxiv(2024)10.1101/2024.07.31.24311312

N/A

0DataRank · unranked

0 citations

Jeffrey P. Spence, Jonathan K. Pritchard, Linda Kachuri, John S. Witte, Jonathan Judd

Unraveling the genetic landscape of susceptibility to multiple primary cancers

medRxiv(2024)10.1101/2024.10.29.24316326

N/A

0DataRank · unranked

0 citations

Linda Kachuri, Jovia L. Nierenberg, Rebecca E. Graff, Taylor B. Cavazos, Thomas J. Hoffmann +10 more

The PRIMED Consortium: Reducing disparities in polygenic risk assessment

UNC Libraries(2024)10.17615/67cq-h633

N/A

0DataRank · unranked

0 citations

John S. Witte, Iman K. Martin, Sally N. Adebamowo, Maggie C. Y. Ng, Eimear E. Kenny +22 more

Investigating the role of neighborhood socioeconomic status and germline genetics on prostate cancer risk

Human Genetics and Genomics Advances(2025)10.1016/j.xhgg.2025.100492

N/A

0DataRank · unranked

1 citations

Jeffrey P. Spence, Jonathan K. Pritchard, Linda Kachuri, John S. Witte, Jonathan Judd

Unraveling the genetic landscape of susceptibility to multiple primary cancers

Human Genetics and Genomics Advances(2025)10.1016/j.xhgg.2025.100413

N/A

0DataRank · unranked

0 citations

Linda Kachuri, Jovia L. Nierenberg, Rebecca E. Graff, Taylor B. Cavazos, Thomas J. Hoffmann +10 more

A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry

UNC Libraries(2024)10.17615/ct6n-5k64

N/A

0DataRank · unranked

0 citations

David V. Conti, J Mehta, Thomas G. Martin, Kenneth C. Anderson, Song, G.C. +65 more

The landscape of host genetic factors involved in immune response to common viral infections

Genome Medicine(2020)10.1186/s13073-020-00790-x

N/A

0DataRank · unranked

126 citations

Stephen Francis, Maike L. Morrison, George A. Wendt, Yohan Bossé, Taylor B. Cavazos +4 more

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

Nature Communications(2020)10.1038/s41467-019-13855-2

N/A

0DataRank · unranked

45 citations

Mattias Johansson, Sara R. Rashkin, Rebecca E. Graff, Yohan Bossé, Venkata Manem +46 more

Genomewide Meta‐Analysis Validates a Role for S1PR1 in Microtubule Targeting Agent‐Induced Sensory Peripheral Neuropathy

Clinical Pharmacology & Therapeutics(2020)10.1002/cpt.1958

N/A

0DataRank · unranked

47 citations

Chenling Xiong, Carol Ho, Taisei Mushiroda, J Chen, Flora Mulkey +13 more

A machine learning approach to optimizing cell-free DNA sequencing panels: with an application to prostate cancer

BMC Cancer(2020)10.1186/s12885-020-07318-x

N/A

0DataRank · unranked

20 citations

Emmalyn Chen, Lancelote Leong, Nima C. Emami, Karen López, Imelda Tenggara +7 more

A two-step approach to testing overall effect of gene–environment interaction for multiple phenotypes

Bioinformatics(2020)10.1093/bioinformatics/btaa1083

N/A

0DataRank · unranked

9 citations

Kathryn S. Burch, Tanushree Haldar, Sriram Sankararaman, Bogdan Paşaniuc, W. James Gauderman +2 more

Association between inflammatory bowel disease and prostate cancer: A large‐scale, prospective, population‐based study

International Journal of Cancer(2020)10.1002/ijc.33048

N/A

0DataRank · unranked

35 citations

Adam B. Weiner, Rebecca E. Graff, Anuj S. Desai, Lauren Folgosa Cooley, William J. Catàlona +7 more

The competing risk of death and selective survival cannot fully explain the inverse cancer‐dementia association

Alzheimer s & Dementia(2020)10.1002/alz.12168

N/A

0DataRank · unranked

31 citations

Sarah F. Ackley, Scott C. Zimmerman, Monica Ospina‐Romero, M. Maria Glymour, Rebecca E. Graff +4 more

A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

Cancer Research(2020)10.1158/0008-5472.can-20-2635

N/A

0DataRank · unranked

25 citations

Taylor B. Cavazos, Sara R. Rashkin, Clinton L. Cario, Rebecca E. Graff, Caroline G. Tai +21 more

Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.28.922088

N/A

0DataRank · unranked

28 citations

Rebecca E. Graff, Karl Smith‐Byrne, Travis J. Meyers, Sara R. Rashkin, Elad Ziv +3 more

Association between inflammatory bowel disease and prostate cancer: A large-scale, prospective, population-based study

medRxiv(2020)10.1101/2020.01.16.20017707

N/A

0DataRank · unranked

4 citations

Adam B. Weiner, Rebecca E. Graff, Anuj S. Desai, Lauren Folgosa Cooley, William J. Catàlona +7 more

Genome-Wide Meta-Analysis Validates a Role for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy

medRxiv(2020)10.1101/2020.04.23.20076208

N/A

0DataRank · unranked

2 citations

Chenling Xiong, Carol Ho, Taisei Mushiroda, J Chen, Flora Mulkey +13 more

A machine learning approach to optimizing cell-free DNA sequencing panels: with an application to prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.30.069658

N/A

0DataRank · unranked

2 citations

Emmalyn Chen, Lancelote Leong, Nima C. Emami, Karen López, Imelda Tenggara +7 more

Cell-free DNA as a biomarker for prostate cancer: elevated concentration and decreased fragment size

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.26.215020

N/A

0DataRank · unranked

0 citations

Clinton L. Cario, Lancelote Leong, Karen López, César Márquez, Carissa Chu +14 more

A Genome-Wide Association Study Identifies Novel Loci for Paclitaxel-Induced Sensory Peripheral Neuropathy in CALGB 40101

UNC Libraries(2020)10.17615/nbbv-eg92

N/A

0DataRank · unranked

0 citations

Chen Jiang, Michiaki Kubo, Deanna L. Kroetz, Kouros Owzar, R. Michael Baldwin +14 more

A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci

UNC Libraries(2020)10.17615/hhzp-hr83

N/A

0DataRank · unranked

0 citations

Elad Ziv, Wendy Cozen, Andrew F. Olshan, Nathaniel Rothman, Thomas G. Martin +95 more

Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts

Nature Communications(2021)10.1038/s41467-021-21288-z

N/A

0DataRank · unranked

130 citations

Taylor B. Cavazos, Khanh K. Thai, Linda Kachuri, Sara R. Rashkin, Joshua Hoffman +16 more

Cell-free DNA concentration and fragment size as a biomarker for prostate cancer

Scientific Reports(2021)10.1038/s41598-021-84507-z

N/A

0DataRank · unranked

79 citations

Clinton L. Cario, Lancelote Leong, Karen López, César Márquez, Carissa Chu +14 more

Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas

Diabetes Care(2021)10.2337/dc21-1152

N/A

0DataRank · unranked

44 citations

Sook Wah Yee, Kaixin Zhou, Nienke van Leeuwen, Yanfei Zhang, Moneeza K. Siddiqui +50 more

Cell-Free DNA Detection of Tumor Mutations in Heterogeneous, Localized Prostate Cancer Via Targeted, Multiregion Sequencing

JCO Precision Oncology(2021)10.1200/po.20.00428

N/A

0DataRank · unranked

11 citations

Clinton L. Cario, Lancelote Leong, Karen López, César Márquez, Patricia Li +14 more

John S. Witte

Indexed papers

Top data-sharing exemplar

Papers