🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Hansruedi Mathys

University of Pittsburgh

ORCID: 0000-0003-0186-2115
NeuroscienceBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile
12.3Author DataRank

Indexed papers

4in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Single-cell multiregion dissection of Alzheimer’s disease

Nature(2024)10.1038/s41586-024-07606-7
Top 6%
4.0DataRank
Top 6%281 citations

Carles B. Adsera, Leyla Anne Akay, Ziting Xia, José Dávila-Velderrain, Ayesha P. Ng +15 more

Papers

Driven by 28 papers — median percentile 93. Top paper: “Single-cell multiregion dissection of Alzheimer’s disease”.

Single-cell multiregion dissection of Alzheimer’s disease

Nature(2024)10.1038/s41586-024-07606-7
Top 6%
4.0DataRank
Top 6%281 citations

Carles B. Adsera, Leyla Anne Akay, Ziting Xia, José Dávila-Velderrain, Ayesha P. Ng +15 more

Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology

Cell(2023)10.1016/j.cell.2023.08.039
Top 6%
3.7DataRank
Top 6%492 citations

Zhuyu Peng, Carles B. Adsera, Matheus B. Victor, Gloria Suella Menchaca, Sudhagar Babu +26 more

Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer’s disease

Nature Neuroscience(2023)10.1038/s41593-023-01334-3
Top 8%
2.6DataRank
Top 8%154 citations

Leyla Anne Akay, Mitchell H. Murdock, Yongjin P. Park, Fabiola Galiana-Melendez, Adele Bubnys +8 more

Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration

Cell(2023)10.1016/j.cell.2023.08.038
N/A
2.5DataRank · unranked
129 citations

Carles B. Adsera, Hansruedi Mathys, Asaf Marco, Gwyneth M. Welch, Hiruy S. Meharena +7 more

Author Correction: Single-cell transcriptomic analysis of Alzheimer’s disease

Nature(2019)10.1038/s41586-019-1329-6
Top 11%
2.0DataRank
Top 11%63 citations

Jose Davila-Velderrain, Zhuyu Peng, Fan Gao, Shahin Mohammadi, Jennie Z. Young +12 more

Single-cell transcriptomic analysis of Alzheimer’s disease

Nature(2019)10.1038/s41586-019-1195-2
N/A
1.2DataRank · unranked
2670 citations

Jose Davila-Velderrain, Zhuyu Peng, Fan Gao, Shahin Mohammadi, Jennie Z. Young +12 more

Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

Cell Reports(2017)10.1016/j.celrep.2017.09.039
N/A
1.0DataRank · unranked
807 citations

Chinnakkaruppan Adaikkan, Fan Gao, Jennie Z. Young, Elodie Manet, Martin Hemberg +6 more

Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease

Nature(2015)10.1038/nature14252
N/A
0.968DataRank · unranked
634 citations

Andreas R. Pfenning, Hansruedi Mathys, Richard Sandstrom, Anshul Kundaje, Li-Huei Tsai +3 more

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes

Nature(2022)10.1038/s41586-022-05439-w
N/A
0.927DataRank · unranked
483 citations

Leyla Anne Akay, José Dávila-Velderrain, Djuna von Maydell, Hansruedi Mathys, Shawn M. Davidson +26 more

Human microglial state dynamics in Alzheimer’s disease progression

Cell(2023)10.1016/j.cell.2023.08.037
N/A
0.893DataRank · unranked
384 citations

Matheus B. Victor, Yongjin P. Park, Xushen Xiong, Aine Ni Scannail, Gloria Suella Menchaca +14 more

Single-cell dissection of the human brain vasculature

Nature(2022)10.1038/s41586-022-04521-7
N/A
0.870DataRank · unranked
330 citations

Na Sun, Hyeseung Lee, Brianna Godlewski, Hansruedi Mathys, Kyriaki Galani +12 more

Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes

Nature Medicine(2020)10.1038/s41591-020-0886-4
N/A
0.852DataRank · unranked
292 citations

Michael Bula, Jose Davila-Velderrain, Leyla Anne Akay, Lena Zhu, Alexander Frank +11 more

Epigenomic dissection of Alzheimer’s disease pinpoints causal variants and reveals epigenome erosion

Cell(2023)10.1016/j.cell.2023.08.040
N/A
0.795DataRank · unranked
199 citations

Benjamin T. James, Carles B. Adsera, Yongjin P. Park, Kyriaki Galani, Matheus B. Victor +12 more

Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer’s disease

Science Translational Medicine(2023)10.1126/scitranslmed.abq1019
N/A
0.731DataRank · unranked
24 citations

Zhuyu Peng, Mitchell H. Murdock, Andrea Spitaleri, Hansruedi Mathys, José Dávila-Velderrain +10 more

A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes

Nature Neuroscience(2022)10.1038/s41593-022-01167-6
N/A
0.697DataRank · unranked
103 citations

Ryan John Cubero, Lida Kanari, Alessandro Venturino, Rouven Schulz, Martina Scolamiero +7 more

Single-cell deconvolution of 3,000 post-mortem brain samples for eQTL and GWAS dissection in mental disorders

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.21.426000
N/A
0.693DataRank · unranked
15 citations

Liang He, Jose Davila-Velderrain, Lei Hou, Shahin Mohammadi, Hansruedi Mathys +6 more

Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition

Cell Reports(2024)10.1016/j.celrep.2024.114876
N/A
0.570DataRank · unranked
22 citations

Michael J. Leone, Michael Kleyman, Alexander Chamessian, Myung‐chul Noh, BaDoi N. Phan +20 more

ABCA7 Loss-of-Function Variants Impact Phosphatidylcholine Metabolism in the Human Brain

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.05.556135
N/A
0.463DataRank · unranked
9 citations

Shannon Wright, Ping-Chieh Pao, Colin Staab, Oisín King, Andrea Spitaleri +14 more

Author Correction: APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes

Nature(2024)10.1038/s41586-024-08434-5
N/A
0.394DataRank · unranked
7 citations

Leyla Anne Akay, José Dávila-Velderrain, Djuna von Maydell, Hansruedi Mathys, Shawn M. Davidson +26 more

Author Correction: Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes

Nature Medicine(2021)10.1038/s41591-021-01250-8
N/A
0.372DataRank · unranked
5 citations

Michael Bula, Jose Davila-Velderrain, Leyla Anne Akay, Lena Zhu, Alexander Frank +11 more

Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer’s disease

Molecular Neurodegeneration(2025)10.1186/s13024-025-00892-3
N/A
0.350DataRank · unranked
9 citations

Pourya Naderi Yeganeh, Carles B. Adsera, Sarah L. Morgan, Hansruedi Mathys, Dmitry Prokopenko +17 more

Single-cell mosaicism analysis reveals cell-type-specific somatic mutational burden in Alzheimer’s Dementia

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.21.489103
N/A
0.341DataRank · unranked
6 citations

Carles B. Adsera, Yongjin P. Park, Hansruedi Mathys, Samuel Sledzieski, Zhuyu Peng +4 more

Single-cell multi-region dissection of brain vasculature in Alzheimer’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.09.479797
N/A
0.338DataRank · unranked
5 citations

Leyla Anne Akay, Mitchell H. Murdock, Yongjin P. Park, Adele Bubnys, Kyriaki Galani +7 more

Author Correction: Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer’s disease

Nature Neuroscience(2023)10.1038/s41593-023-01507-0
N/A
0.247DataRank · unranked
3 citations

Leyla Anne Akay, Mitchell H. Murdock, Yongjin P. Park, Fabiola Galiana-Melendez, Adele Bubnys +8 more

Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.13.632801
N/A
0.216DataRank · unranked
3 citations

Pourya Naderi Yeganeh, Carles B. Adsera, Sarah L. Morgan, Hansruedi Mathys, Dmitry Prokopenko +16 more

A molecular and spinal circuit basis for the functional segregation of itch and pain

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.31.667966
N/A
0.165DataRank · unranked
2 citations

Kelly A. Corrigan, Sean-Paul G. Williams, Cédric Peirs, Michael J. Leone, Daniel J. Headrick +13 more

Multi‐polygenic score model informs the genetic basis of heterogeneity in Alzheimer’s disease

Alzheimer's & Dementia(2023)10.1002/alz.079231
N/A
0.126DataRank · unranked
1 citations

Na Sun, William F Li, Carles B. Adsera, Kyriaki Galani, Hansruedi Mathys +4 more

Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience

Cell(2025)10.1016/j.cell.2025.06.031
N/A
0DataRank · unranked
38 citations

Shanshan Zhang, Benjamin T. James, Kyriaki Galani, Riley J. Mangan, Stuart B. Fass +27 more