Mark Mapstone

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.8Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS) study

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12039

Top 30%

0.674DataRank

Top 30%23 citations

Fan Zhang, Nicole Schupf, Sharon J. Krinsky‐McHale, James Hall, Mark Mapstone +18 more

Papers

Driven by 56 papers — median percentile 55. Top paper: “A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer’s disease”.

A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer’s disease

GeroScience(2022)10.1007/s11357-022-00580-w

N/A

1.2DataRank · unranked

41 citations

Maria Giulia Bacalini, Ricardo Miramontes, Alessio Boattini, Cristian Taccioli, Giorgia Modenini +11 more

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2022)10.1016/s1474-4422(22)00408-2

N/A

1.1DataRank · unranked

56 citations

Brian A. Gordon, Julie K. Wisch, Shaney Flores, Rachel L. Henson, Omar H. Butt +95 more

Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study

The Lancet Neurology(2015)10.1016/s1474-4422(15)00178-7

N/A

0.811DataRank · unranked

222 citations

Cory Y. McLean, Jacqueline Rick, Shirley Eberly, Samantha J. Hutten, Katrina Gwinn +40 more

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS) study

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12039

Top 30%

0.674DataRank

Top 30%23 citations

Fan Zhang, Nicole Schupf, Sharon J. Krinsky‐McHale, James Hall, Mark Mapstone +18 more

The Alzheimer's Biomarker Consortium–Down Syndrome (ABC‐DS): A 10‐year report

Alzheimer s & Dementia(2025)10.1002/alz.70294

N/A

0.601DataRank · unranked

22 citations

Mark Mapstone, Sigan L. Hartley, Howard Andrews, Brad T. Christian, Joseph H. Lee +20 more

Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer’s Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome

Journal of Alzheimer s Disease(2020)10.3233/jad-201167

N/A

0.598DataRank · unranked

53 citations

Michael S. Rafii, Fan Zhang, James Hall, David Julovich, Beau M. Ances +20 more

Evaluation of Neighborhood-Level Disadvantage and Cognition in Mexican American and Non-Hispanic White Adults 50 Years and Older in the US

JAMA Network Open(2023)10.1001/jamanetworkopen.2023.25325

Top 33%

0.589DataRank

Top 33%22 citations

Justin B. Miller, Fan Zhang, Robert A. Rissman, Rema Raman, James Hall +34 more

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00084-x

N/A

0.542DataRank · unranked

36 citations

Nicole S. McKay, Anna H. Boerwinkle, James L. Kennedy, Shaney Flores, Benjamin L. Handen +86 more

Cerebrovascular disease is associated with Alzheimer’s plasma biomarker concentrations in adults with Down syndrome

Brain Communications(2024)10.1093/braincomms/fcae331

N/A

0.510DataRank · unranked

29 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +70 more

Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00426-5

N/A

0.505DataRank · unranked

28 citations

Matthew Zammit, Jiebiao Wang, Benjamin L. Handen, Tobey J. Betthauser, Charles M. Laymon +71 more

Mid-life anti-inflammatory metabolites are inversely associated with long-term cardiovascular disease events

EBioMedicine(2025)10.1016/j.ebiom.2024.105551

N/A

0.396DataRank · unranked

13 citations

Chris McKennan, Jiaxuan Duan, Yueh-Ning Yang, Kevin E. Kip, David N. Finegold +9 more

The striatum is an early, accurate indicator of amyloid burden using [ 11 C]PiB in Down syndrome: Comparison of two radiotracers

Alzheimer s & Dementia(2025)10.1002/alz.70141

N/A

0.385DataRank · unranked

12 citations

Brecca Bettcher, Andrew K McVea, Alexandra H DiFilippo, Matthew Zammit, Lisette LeMerise +21 more

Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer’s disease and related neurodegenerative pathologies using 7T postmortem MRI

Journal of Neuropathology & Experimental Neurology(2025)10.1093/jnen/nlaf010

N/A

0.312DataRank · unranked

7 citations

Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini, Jaehoon Noh +69 more

The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome

EBioMedicine(2024)10.1016/j.ebiom.2024.105433

N/A

0.299DataRank · unranked

6 citations

Lam‐Ha T. Dang, Alice Lee, Sharon J. Krinsky‐McHale, Deborah Pang, Lisa Melilli +72 more

2024 VCP International Conference: Exploring multi-disciplinary approaches from basic science of valosin containing protein, an AAA+ ATPase protein, to the therapeutic advancement for VCP-associated multisystem proteinopathy

Neurobiology of Disease(2025)10.1016/j.nbd.2025.106861

N/A

0.292DataRank · unranked

6 citations

Amal Dadi, Zollie Yavarow, Lindsay N. Alfano, Daniel J. Anderson, Michelle R. Arkin +36 more

Longitudinal changes in white matter hyperintensity volume accelerate across the Alzheimer's continuum in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70679

Top 57%

0.283DataRank

Top 57%5 citations

Natalie Edwards, Lisi Flores Aguilar, Mohamad J. Alshikho, Anna Smith, Rachel LeMay +13 more

Alzheimer's disease diagnostic progression is associated with cerebrovascular disease and neuroinflammation in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70726

N/A

0.241DataRank · unranked

4 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +20 more

Multiomic Evidence for a Unified Model of Alzheimer’s Disease Etiology Linking Microglial Flux Capacity and Astrocyte-Neuron Metabolic Breakdown

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.23.604835

N/A

0.241DataRank · unranked

4 citations

Jennifer A. Rohrs, Timothy J. Hohman, Mark Mapstone, Peter J. Meikle, Rima Kaddurah-Daouk +5 more

Chronic emotional stress and mediating role of Interleukin-6 in the association with cardiometabolic disorders in a multiethnic middle-aged and older US population

International Journal of Cardiology Cardiovascular Risk and Prevention(2025)10.1016/j.ijcrp.2025.200510

Top 65%

0.208DataRank

Top 65%3 citations

Sid E. O’Bryant, Kristine Yaffe, Arthur W. Toga, Robert A. Rissman, Leigh Johnson +35 more

The tau biomarker cascade is condensed in Down syndrome compared with sporadic Alzheimer’s disease

Brain(2025)10.1093/brain/awaf428

N/A

0.165DataRank · unranked

2 citations

Hailey Bruzzone, Karly Alex Cody, Jacob Morse, Rachael E. Wilson, Brecca Bettcher +65 more

Pathways linking pulse pressure to dementia in adults with Down syndrome

medRxiv(2023)10.1101/2023.10.26.23297625

N/A

0DataRank · unranked

0 citations

Patrick J. Lao, Mithra Sathishkumar, Lisa Taylor, Nazek Queder, Liv McMillan +17 more

Associations between saliva and plasma cytokines in cognitively normal, older adults

Aging Clinical and Experimental Research(2022)10.1007/s40520-022-02292-9

N/A

0DataRank · unranked

37 citations

Soyun Kim, A Piradov Mikhail, Rond Malhas, Liv McMillan, Martina K. Hollearn +5 more

TGFβ Drives Metabolic Perturbations during Epithelial Mesenchymal Transition in Pancreatic Cancer: TGFβ Induced EMT in PDAC

Cancers(2021)10.3390/cancers13246204

N/A

0DataRank · unranked

17 citations

Shivani Bansal, Prabhjit Kaur, Shreyans K. Jain, Tatiana Altadil, Charles P. Hinzman +14 more

Cerebrovascular disease emerges with age and Alzheimer’s disease in adults with Down syndrome

Scientific Reports(2024)10.1038/s41598-024-61962-y

N/A

0DataRank · unranked

28 citations

Natalie Edwards, Lisi Flores Aguilar, Mohamad J. Alshikho, Batool Rizvi, Dana Tudorascu +11 more

Metabolic correlates of prevalent mild cognitive impairment and Alzheimer's disease in adults with Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12028

N/A

0DataRank · unranked

23 citations

Thomas Groß, Fabìo Macciardi, Amrita K. Cheema, Melissa Petersen, Elizabeth Head +7 more

Blood biomarkers in Down syndrome: Facilitating Alzheimer's disease detection and monitoring

Alzheimer s & Dementia(2024)10.1002/alz.14364

N/A

0DataRank · unranked

17 citations

Lisi Flores Aguilar, Elizabeth Head, Laia Montoliu‐Gaya, André Strydom, Sarah E. Pape +9 more

Whole genome‐wide sequence analysis of long‐lived families (Long‐Life Family Study) identifies MTUS2 gene associated with late‐onset Alzheimer's disease

Alzheimer s & Dementia(2024)10.1002/alz.13718

N/A

0DataRank · unranked

17 citations

Stephanie Cosentino, Badri N. Vardarajan, Richard Mayeux, Thomas T. Perls, Stacy L. Andersen +14 more

Cognitive and functional performance and plasma biomarkers of early Alzheimer's disease in Down syndrome

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2024)10.1002/dad2.12582

N/A

0DataRank · unranked

16 citations

Benjamin L. Handen, Melissa Petersen, Sid E. O’Bryant, Jamie C. Peven, Dana Tudorascu +17 more

Sex‐specific associations between AD genotype and the microbiome of human amyloid beta knock‐in (hAβ‐KI) mice

Alzheimer s & Dementia(2024)10.1002/alz.13794

N/A

0DataRank · unranked

14 citations

Julio Avelar‐Barragan, Jason A. Rothman, Eric D. Adams, Gina Faraci, Stefânia Forner +8 more

The amyloid beta 42/38 ratio as a plasma biomarker of early memory deficits in cognitively unimpaired older adults

Neurobiology of Aging(2024)10.1016/j.neurobiolaging.2024.08.009

N/A

0DataRank · unranked

4 citations

Jenna N. Adams, Soyun Kim, Liv McMillan, Rond Malhas, Mark Mapstone +4 more

A pathway linking pulse pressure to dementia in adults with Down syndrome

Brain Communications(2024)10.1093/braincomms/fcae157

N/A

0DataRank · unranked

3 citations

Patrick J. Lao, Mithra Sathishkumar, Lisa Taylor, Nazek Queder, Liv McMillan +17 more

Cognitively supernormal older adults maintain a unique structural connectome that is resistant to Alzheimer’s pathology

NeuroImage Clinical(2020)10.1016/j.nicl.2020.102413

N/A

0DataRank · unranked

10 citations

Timothy M. Baran, Brian Rooks, M. Kerry O’Banion, Mark Mapstone, Zhengwu Zhang +2 more

Characterization of plasma AT(N) biomarkers among a racial and ethnically diverse community‐based cohort: an HABS‐HD study

Alzheimer s & Dementia Translational Research & Clinical Interventions(2025)10.1002/trc2.70045

N/A

0DataRank · unranked

16 citations

Fan Zhang, James Hall, Courtney Brock, Robert A. Rissman, Tori Como +14 more

The Alzheimer's Biomarker Consortium‐Down Syndrome: Rationale and methodology

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2020)10.1002/dad2.12065

N/A

0DataRank · unranked

122 citations

Ira T. Lott, Bradley T. Christian, Nicole Schupf, Sid E. O’Bryant, Mark Mapstone +17 more

Regional differences in astrocytic Aquaporin-4 protein levels and distribution in aging and Alzheimer's disease in down syndrome

Neurobiology of Disease(2025)10.1016/j.nbd.2025.107114

N/A

0DataRank · unranked

7 citations

Haley Miyasato, Kevin Camey, Krina A Ghadia, Elizabeth J. Andrews, Phong Ngo +17 more

The effect of APOE4 on Alzheimer’s plasma biomarkers among Mexican Americans in the HABS-HD cohort

Alzheimer s Research & Therapy(2025)10.1186/s13195-025-01845-0

N/A

0DataRank · unranked

6 citations

Nancy Ortega, Kimberly Espejo, Vahan Aslanyan, Judy Pa, The HABS-HD Study Team +39 more

A neuropathology case report of a woman with Down syndrome who remained cognitively stable: Implications for resilience to neuropathology

Alzheimer s & Dementia(2025)10.1002/alz.14479

N/A

0DataRank · unranked

14 citations

Jerry J. Lou, Lisi Flores Aguilar, Jamie Nakagiri, William H. Yong, Christy Hom +19 more

Mediating role of Interleukin-6 in the predictive association of diabetes with Hippocampus atrophy, Amyloid, Tau, and Neurofilament pathology at pre-clinical stages of diabetes-related cognitive impairment

Brain Behavior & Immunity - Health(2025)10.1016/j.bbih.2025.101031

N/A

0DataRank · unranked

6 citations

Sid E. O'Bryant, Kristine Yaffe, Arthur Toga, Robert Rissman, Leigh Johnson +35 more

Salivary levels of amyloid beta reflect brain amyloid beta burden in cognitively-normal older adults

The Journal of Prevention of Alzheimer s Disease(2025)10.1016/j.tjpad.2025.100216

N/A

0DataRank · unranked

4 citations

Jenna N. Adams, Soyun Kim, Lisa M. Taylor, Nandita Tuteja, Liv McMillan +14 more

PET‐measured amyloid beta accumulates at an accelerated rate in Down syndrome compared to neurotypical populations

Alzheimer s & Dementia(2025)10.1002/alz.70357

N/A

0DataRank · unranked

4 citations

Alexandra H DiFilippo, Max McLachlan, Brecca Betcher, Matthew Zammit, Tobey J. Betthauser +20 more

Examination of metabolic syndrome in Down syndrome and association with dementia

Alzheimer s & Dementia(2025)10.1002/alz.70799

N/A

0DataRank · unranked

3 citations

Lam‐Ha T. Dang, Laura Xicota, Sharon J. Krinsky‐McHale, Balaji Kannappan, Adam M. Brickman +8 more

Association of mid-life cardiovascular risk with biomarkers of Alzheimer's disease, neurodegeneration, and white matter hyperintensities: Heart SCORE brain study

Journal of Alzheimer s Disease Reports(2025)10.1177/25424823241299297

N/A

0DataRank · unranked

5 citations

Yue-Fang Chang, Justin Swanson, Michael Vu, Mark Mapstone, Victor L. Villemagne +11 more

Longitudinal diffusion tensor imaging correlates with amyloid burden in Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70572

N/A

0DataRank · unranked

2 citations

José Guerrero-González, Andrew K McVea, Matthew Zammit, Steven Kecskemeti, Sigan L. Hartley +7 more

A comparison of multiple amyloid PET radiotracers for Down syndrome clinical trials

Brain Communications(2025)10.1093/braincomms/fcaf406

N/A

0DataRank · unranked

2 citations

Julie C. Price, Bradley T. Christian, Michael S. Rafii, Beau M. Ances, Howard Andrews +51 more

Imaging and plasma biomarkers for pathological accumulation in Down syndrome

Brain(2025)10.1093/brain/awaf418

N/A

0DataRank · unranked

2 citations

Ziqiao Jiao, James T. Kennedy, Ann D. Cohen, Zinayida Schlachetzki, Melissa Petersen +21 more

Genome‐wide association analyses identify candidate loci for amyloid imaging and plasma biomarkers in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70358

N/A

0DataRank · unranked

0 citations

Lam‐Ha T. Dang, Ruyu Shi, Kang-Hsien Fan, Asma Naseer Cheema, Laura Xicota +16 more

Weight Loss and Alzheimer’s Disease in Down Syndrome

Journal of Alzheimer s Disease(2022)10.3233/jad-220865

N/A

0DataRank · unranked

12 citations

Brian C. Helsel, Lauren T. Ptomey, H. Diana Rosas, Benjamin L. Handen, Charles M. Laymon +10 more

Networks and clusters of immunometabolic biomarkers and depression-associated features in middle-aged and older community-dwelling US adults with and without depression

Brain Behavior & Immunity - Health(2025)10.1016/j.bbih.2025.101103

N/A

0DataRank · unranked

0 citations

Sid E. O’Bryant, Kristine Yaffe, Arthur W. Toga, Robert A. Rissman, Leigh Johnson +35 more

Associations between saliva and plasma cytokines and YKL-40 in cognitively-normal, older adults

Research Square(2022)10.21203/rs.3.rs-1863157/v1

N/A

0DataRank · unranked

1 citations

Soyun Kim, Abanoub Mikhail, Liv McMillan, Rond Malhas, Martina K. Hollearn +5 more

Integrative metabolomics science in Alzheimer’s disease: Relevance and future perspectives

Ageing Research Reviews(2023)10.1016/j.arr.2023.101987

N/A

0DataRank · unranked

64 citations

Raúl González‐Domínguez, Susana López‐Ortiz, Álvaro González‐Domínguez, Héctor Menéndez, Juan Martín‐Hernández +14 more

Impact of the COVID-19 pandemic on daily life, mood, and behavior of adults with Down syndrome

Disability and health journal(2022)10.1016/j.dhjo.2022.101278

N/A

0DataRank · unranked

20 citations

Victoria Fleming, Brianna Piro‐Gambetti, Annie Cohen, Beau M. Ances, Michael A. Yassa +13 more

Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome

Alzheimer s & Dementia(2023)10.1002/alz.13506

N/A

0DataRank · unranked

13 citations

Muhammad Aslam, Lam‐Ha T. Dang, Laura Xicota, María Victoria Fernández, Yun Ju Sung +16 more

Plasma NT1‐tau and Aβ42 correlate with age and cognitive function in two large Down syndrome cohorts

Alzheimer s & Dementia(2023)10.1002/alz.13382

N/A

0DataRank · unranked

9 citations

Kathryn L. Van Pelt, Lei Liu, Amirah K. Anderson, Beth L. Ostaszewski, Mark Mapstone +8 more

Predictors of Cognitive Change in Parkinson Disease

Alzheimer Disease & Associated Disorders(2023)10.1097/wad.0000000000000576

N/A

0DataRank · unranked

8 citations

Sarah Duff‐Canning, Eric McArthur, Melissa J. Armstrong, Susan H. Fox, Christopher Meaney +14 more

Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndrome

medRxiv(2023)10.1101/2023.11.28.23298693

N/A

0DataRank · unranked

10 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +20 more

Plasma NT1-tau and Aβ 42 correlate with age and cognitive function in two large Down syndrome cohorts

medRxiv(2023)10.1101/2023.03.10.23287109

N/A

0DataRank · unranked

2 citations

Kathryn L. Van Pelt, Lei Liu, Amirah K. Anderson, Beth L. Ostaszewski, Mark Mapstone +8 more

Mark Mapstone

Indexed papers

Top data-sharing exemplar

Papers