John Karanicolas

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 26 papers. Top paper: “Rosetta3: An Object-Oriented Software Suite for the Simulation and Design of Macromolecules”.

Rosetta3: An Object-Oriented Software Suite for the Simulation and Design of Macromolecules

UNC Libraries(2020)10.17615/8ga2-9t05

N/A

0.752DataRank · unranked

149 citations

Monica Berrondo, Andrew Leaver-Fay, James Thompson, S. I. Cooper, Daniel J. Mandell +27 more

Druggable Protein Interaction Sites Are More Predisposed to Surface Pocket Formation than the Rest of the Protein Surface

PLoS Computational Biology(2013)10.1371/journal.pcbi.1002951

N/A

0.695DataRank · unranked

102 citations

John Karanicolas, David K. Johnson

DARC: Mapping Surface Topography by Ray-Casting for Effective Virtual Screening at Protein Interaction Sites

Journal of Medicinal Chemistry(2016)10.1021/acs.jmedchem.5b00150

N/A

0.477DataRank · unranked

23 citations

Sven A. Miller, Steven Rogers, Jittasak Khowsathit, Lan Lan, Nan Bai +8 more

Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry

Research Square(2023)10.21203/rs.3.rs-2395172/v1

N/A

0.292DataRank · unranked

6 citations

Yusuf Adeshina, Igor Bychkov, Yan Xia, Ragul Gowthaman, Sven A. Miller +10 more

Rationalizing PROTAC-mediated ternary complex formation using Rosetta

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.27.119347

N/A

0DataRank · unranked

17 citations

Palani Kirubakaran, John Karanicolas, Nan Bai

Machine learning classification can reduce false positives in structure-based virtual screening

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.10.902411

N/A

0DataRank · unranked

10 citations

Eric J. Deeds, John Karanicolas, Yusuf Adeshina

A clinically-relevant polymorphism in the Na + /taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.02.184424

N/A

0DataRank · unranked

1 citations

Shipra Malhotra, Aron W. Fenton, Liskin Swint‐Kruse, John Karanicolas, Bruno Hagenbuch +1 more

Computational design of affinity and specificity at protein–protein interfaces

UNC Libraries(2020)10.17615/g42d-mf39

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, John Karanicolas

Efficient Hit-to-Lead Searching of Kinase Inhibitor Chemical Space via Computational Fragment Merging

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.01.446684

N/A

0DataRank · unranked

2 citations

Wern Juin Gabriel Ong, Ilya G. Serebriiskii, John Karanicolas, Grigorii Andrianov

The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors

Cellular and Molecular Life Sciences(2022)10.1007/s00018-022-04321-2

N/A

0DataRank · unranked

54 citations

Rajendra P. Pangeni, Igor Bychkov, Sven A. Miller, Evgeny Izumchenko, Jindan Yu +4 more

Integrative genome-wide analysis reveals EIF3A as a key downstream regulator of translational repressor protein Musashi 2 (MSI2)

NAR Cancer(2022)10.1093/narcan/zcac015

N/A

0DataRank · unranked

18 citations

Oscar Ramirez, Kiran Paul, Abhishek Gupta, Vandana Kumari, Valentina Botti +7 more

Structural Plasticity Is a Feature of Rheostat Positions in the Human Na+/Taurocholate Cotransporting Polypeptide (NTCP)

International Journal of Molecular Sciences(2022)10.3390/ijms23063211

N/A

0DataRank · unranked

10 citations

Shipra Malhotra, Aron W. Fenton, Liskin Swint‐Kruse, John Karanicolas, Bruno Hagenbuch +1 more

An African-Specific Variant of TP5 3 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1315

N/A

0DataRank · unranked

29 citations

Jessica C. Leung, Sven A. Miller, Julia I-Ju Leu, James F. Dougherty, Nicole L. Clarke +22 more

Secreted folate receptor γ drives fibrogenesis in metabolic dysfunction–associated steatohepatitis by amplifying TGFβ signaling in hepatic stellate cells

Science Translational Medicine(2023)10.1126/scitranslmed.ade2966

N/A

0DataRank · unranked

15 citations

Mario C. Rico, Carmen Merali, Carlos A. Barrero, Óscar Cano Pérez, Victoria Mischley +4 more

Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.09.523326

N/A

0DataRank · unranked

4 citations

Yusuf Adeshina, Igor Bychkov, Yan Xia, Ragul Gowthaman, Sven A. Miller +10 more

Musashi-2 (MSI2) regulation of DNA damage response in lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.13.544756

N/A

0DataRank · unranked

3 citations

Alexander Y. Deneka, Iuliia Topchu, Rajendra P. Pangeni, Christopher J. Lengner, John Karanicolas +4 more

Data from An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

(2023)10.1158/2159-8290.c.6700223

N/A

0DataRank · unranked

0 citations

Jessica C. Leung, Sven A. Miller, Julia I-Ju Leu, James F. Dougherty, Nicole L. Clarke +22 more

Data from An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

(2023)10.1158/2159-8290.c.6700223.v2

N/A

0DataRank · unranked

0 citations

Jessica C. Leung, Sven A. Miller, Julia I-Ju Leu, James F. Dougherty, Nicole L. Clarke +22 more

PPIscreenML: Structure-based screening for protein-protein interactions using AlphaFold

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.16.585347

N/A

0DataRank · unranked

3 citations

Johannes Maier, Jesse Chen, John Karanicolas, Victoria Mischley

PPIscreenML is a method for structure-based screening of protein-protein interactions using AlphaFold

eLife(2024)10.7554/elife.98179

N/A

0DataRank · unranked

3 citations

Johannes Maier, Jesse Chen, John Karanicolas, Victoria Mischley

Musashi-2 (MSI2) regulation of DNA damage response in lung cancer

Research Square(2024)10.21203/rs.3.rs-4021568/v1

N/A

0DataRank · unranked

2 citations

Alexander Y. Deneka, Iuliia Topchu, Ragendra Pangeni, Amr Ismail, Christopher J. Lengner +5 more

vScreenML v2.0: Improved Machine Learning Classification for Reducing False Positives in Structure-Based Virtual Screening

International Journal of Molecular Sciences(2024)10.3390/ijms252212350

N/A

0DataRank · unranked

0 citations

Emeline Haroldsen, John Karanicolas, Grigorii Andrianov

Rescuing the Function of Missense-Mutated Tumor Suppressor VHL using Stabilizing Small Molecules

10.7554/elife.110305.1

N/A

0DataRank · unranked

0 citations

Christopher S Parry, Sven A Miller, Shipra Malhotra, Glenn A Doyle, Ezra Shimabenga +11 more

Identification and Validation of an Aspergillus nidulans Secondary Metabolite Derivative as an Inhibitor of the Musashi-RNA Interaction

Cancers(2020)10.3390/cancers12082221

N/A

0DataRank · unranked

22 citations

Jiajun Liu, Minli Xing, Amber R. Smith, Jinan Wang, Xiaoqing Wu +13 more

A clinically relevant polymorphism in the Na+/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.014889

N/A

0DataRank · unranked

31 citations

Shipra Malhotra, Aron W. Fenton, Liskin Swint‐Kruse, John Karanicolas, Bruno Hagenbuch +1 more

Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis

Communications Biology(2020)10.1038/s42003-020-0933-1

N/A

0DataRank · unranked

112 citations

Gulhumay Gardashova, Lan Lan, Shuang Han, Cuncong Zhong, Rebecca T. Marquez +13 more