Francis Castellino

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 20 papers. Top paper: “Altered Smooth Muscle Cell Histone Acetylome by the SPHK2/S1P Axis Promotes Pulmonary Hypertension”.

Altered Smooth Muscle Cell Histone Acetylome by the SPHK2/S1P Axis Promotes Pulmonary Hypertension

Circulation Research(2023)10.1161/circresaha.123.322740

N/A

0.464DataRank · unranked

21 citations

Maggie Holohan, Kalyn M. Borger, Deborah L. Donahue, Rafael D. Kuc, Martin Gerig +5 more

Binding of the kringle‐2 domain of human plasminogen to streptococcal PAM‐type M‐protein causes dissociation of PAM dimers

MicrobiologyOpen(2021)10.1002/mbo3.1252

N/A

0.269DataRank · unranked

5 citations

Yetunde A. Ayinuola, Cunjia Qiu, Shaun W. Lee, Victoria A. Ploplis, Francis Castellino +1 more

Evolution of Streptococcus pyogenes has maximized the efficiency of the Sortase A cleavage motif for cell wall transpeptidation

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101940

N/A

0.165DataRank · unranked

2 citations

Yetunde A. Ayinuola, Brady T. Russo, Zhong Liang, Shaun W. Lee, Victoria A. Ploplis +3 more

Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI.

Research Square(2023)10.21203/rs.3.rs-3263501/v1

N/A

0.104DataRank · unranked

1 citations

Jonathan Molina, Kurt N. Kohler, Christopher Gager, Marissa J. Andersen, Ellsa Wongso +13 more

Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice

UNC Libraries(2020)10.17615/g71y-sp71

N/A

0DataRank · unranked

0 citations

L. G. Ellies, N. Yokota, N. Mackman, A. Zarpellon, András Gruber +6 more

Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier

Science(2021)10.1126/science.abl5450

N/A

0DataRank · unranked

188 citations

Andrew D. Doyle, Teresa Greenwell‐Wild, Nicolás Dutzan, Collin L. Tran, Loreto Abusleme +19 more

Group A Streptococcus-Induced Activation of Human Plasminogen Is Required for Keratinocyte Wound Retraction and Rapid Clot Dissolution

Frontiers in Cardiovascular Medicine(2021)10.3389/fcvm.2021.667554

N/A

0DataRank · unranked

14 citations

Daniel E. Hammers, Zhong Liang, Gabrielle L. Nguyen, Mary E. Benz, Thomas E. Moran +9 more

Fibrin is a critical regulator of neutrophil effector function at mucosal barrier sites

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.15.426743

N/A

0DataRank · unranked

4 citations

Andrew D. Doyle, Collin L. Tran, Teresa Greenwell‐Wild, Nicolás Dutzan, Andrew Gary Lum +11 more

Inactivation of the lysine binding sites of human plasminogen (hPg) reveals novel structural requirements for the tight hPg conformation, M-protein binding, and rapid activation

Frontiers in Molecular Biosciences(2023)10.3389/fmolb.2023.1166155

N/A

0DataRank · unranked

7 citations

Francis Castellino, Yetunde A. Ayinuola

Generation and characterization of a plasminogen-binding group A streptococcal M-protein/streptokinase-sensitive mouse line

Journal of Thrombosis and Haemostasis(2023)10.1016/j.jtha.2023.02.028

N/A

0DataRank · unranked

2 citations

Deborah L. Donahue, Jermilia Charles, Zhong Liang, Francis Castellino, Victoria A. Ploplis +1 more

A high-resolution cryo-EM structure of a bacterial M-protein reveals a compact structure that diverges from related M-proteins

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.18.558297

N/A

0DataRank · unranked

0 citations

Sheiny Tjia-Fleck, Nathan R. McCann, Yetunde A. Ayinuola, Francis Castellino, Bradley M. Readnour

Group A Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.04.560727

N/A

0DataRank · unranked

0 citations

Zhong Liang, Yun‐Juan Bao, Paulina G. Carles, Jessica C. Keane, Madelyn G. Cerney +6 more

Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI

Nature Communications(2024)10.1038/s41467-024-46974-6

N/A

0DataRank · unranked

21 citations

K. Köhler, Christopher Gager, Marissa J. Andersen, Ellsa Wongso, Elizabeth R. Lucas +13 more

Group a Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination

Microbiology Spectrum(2025)10.1128/spectrum.02607-24

N/A

0DataRank · unranked

3 citations

Thomas E. Moran, Zhong Liang, Yun‐Juan Bao, Paulina G. Carles, Jessica C. Keane +7 more

Hydrophobic residues in the D‐domain of a plasminogen‐binding M‐protein modulate α‐helicity, oligomerization, and surface anchoring in Streptococcus pyogenes

Protein Science(2025)10.1002/pro.70287

N/A

0DataRank · unranked

1 citations

Yetunde A. Ayinuola, Zhong Liang, Francis Castellino, Olawole Ayinuola

The Streptococcal Protease SpeB Antagonizes the Biofilms of the Human Pathogen Staphylococcus aureus USA300 through Cleavage of the Staphylococcal SdrC Protein

Journal of Bacteriology(2020)10.1128/jb.00008-20

N/A

0DataRank · unranked

25 citations

Zhong Liang, Jeffrey A. Mayfield, Deborah L. Donahue, Mijoon Lee, Bill Boggess +4 more

Interactions between membrane-bound streptococcal alpha-enolase and human plasminogen captured through cryogenic-electron microscopy

Frontiers in Molecular Biosciences(2025)10.3389/fmolb.2025.1666748

N/A

0DataRank · unranked

0 citations

Bradley M. Readnour, Zhong Liang, Yetunde A. Ayinuola, Francis Castellino, Sheiny Tjia-Fleck

The M Protein of Streptococcus pyogenes Strain AP53 Retains Cell Surface Functional Plasminogen Binding after Inactivation of the Sortase A Gene

Journal of Bacteriology(2020)10.1128/jb.00096-20

N/A

0DataRank · unranked

12 citations

Yetunde A. Ayinuola, Damini Singh, Katelyn E. Carothers, Vincent A. Fischetti, Ana L. Flores‐Mireles +5 more

Streptococcus co-opts a conformational lock in human plasminogen to facilitate streptokinase cleavage and bacterial virulence

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.016262

N/A

0DataRank · unranked

12 citations

Teresa Brito-Robinson, Olawole Ayinuola, Julia Beck, Diana Cruz‐Topete, Shaun W. Lee +3 more

In situ metabolite and lipid analysis of GluN2D−/− and wild-type mice after ischemic stroke using MALDI MSI

Analytical and Bioanalytical Chemistry(2020)10.1007/s00216-020-02477-z

N/A

0DataRank · unranked

24 citations

Deborah L. Donahue, Adam Holmes, Rashna D. Balsara, Francis Castellino, Amanda B. Hummon +1 more