Mark Donowitz

Also affiliated with Johns Hopkins Medicine

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 30 papers. Top paper: “Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulation”.

Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulation

American Journal of Physiology-Gastrointestinal and Liver Physiology(2021)10.1152/ajpgi.00177.2021

N/A

0.638DataRank · unranked

16 citations

Sue E. Crawford, Carolyn Bomidi, Xi‐Lei Zeng, James R. Broughman, Matthew J. Robertson +8 more

Mucus layer modeling of human colonoids during infection with enteroaggragative E. coli

Scientific Reports(2020)10.1038/s41598-020-67104-4

N/A

0.619DataRank · unranked

61 citations

Waleska Saitz-Rojas, Rachel Smith, Laura A. Gonyar, Julie In, Olga Kovbasnjuk +5 more

Loss of PI3k activity of inositol polyphosphate multikinase impairs PDK1-mediated AKT activation, cell migration, and intestinal homeostasis

iScience(2023)10.1016/j.isci.2023.106623

N/A

0.500DataRank · unranked

27 citations

Evan R. Semenza, George Koshkaryan, Subrata H. Mishra, Sujan Chatterjee, Efrat Abramson +7 more

Farnesoid X receptor enhances epithelial ACE2 expression and inhibits virally induced IL-6 secretion: implications for intestinal symptoms of SARS-CoV-2

American Journal of Physiology-Gastrointestinal and Liver Physiology(2023)10.1152/ajpgi.00099.2023

N/A

0.406DataRank · unranked

7 citations

Jennifer K. Truong, Anuradha Rao, Ruxian Lin, Jennifer Foulke‐Abel, Luciano Adorini +4 more

Calcium-sensing receptor activator cinacalcet for treatment of cyclic nucleotide-mediated secretory diarrheas

Translational research(2023)10.1016/j.trsl.2023.09.001

N/A

0.360DataRank · unranked

10 citations

Pattareeya Yottasan, Lívia de Souza Gonçalves, Apurva A. Oak, Ruxian Lin, Ming Tse +3 more

The Air–Liquid Interface Reorganizes Membrane Lipids and Enhances the Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colonoid Monolayers

International Journal of Molecular Sciences(2023)10.3390/ijms24098273

N/A

0.345DataRank · unranked

9 citations

Zixin Zhang, Ruxian Lin, Rafiquel Sarker, Mark Donowitz, Varsha Singh +1 more

Cholinergic-induced anion secretion in murine jejunal enteroids involves synergy between muscarinic and nicotinic pathways

American Journal of Physiology-Cell Physiology(2020)10.1152/ajpcell.00179.2020

N/A

0.330DataRank · unranked

8 citations

Jianyi Yin, Julie In, Subhash Kulkarni, Pankaj J. Pasricha, Chung‐Ming Tse +2 more

Loss of PI3-kinase activity of inositol polyphosphate multikinase impairs PDK1-mediated AKT activation, cell migration and intestinal homeostasis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.18.423145

N/A

0.269DataRank · unranked

5 citations

Luke Reilly, Evan R. Semenza, Efrat Abramson, Subrata H. Mishra, Yoshitasu Sei +4 more

Adipokine C1q/Tumor necrosis factor-Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation via Histone Deacetylase Sirtuin 1 (SIRT1)/NF-κB Signaling

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.08.491034

N/A

0.104DataRank · unranked

1 citations

Zixin Zhang, Gangping Li, Yan Feng, Lingling Xian, Fatemeh Bakhsh +9 more

mOrange2, a Genetically Encoded, pH Sensitive Fluorescent Protein, is an Alternative to BCECF-AM to Measure Intracellular pH to Determine NHE3 and DRA Activity

Cellular Physiology and Biochemistry(2022)10.33594/000000493

N/A

0DataRank · unranked

4 citations

Chung‐Ming Tse, Ruxian Lin, George McNamara, Varsha Singh, Mark Donowitz +1 more

Has a physiologic function for NHE2 finally been identified?

Acta Physiologica(2022)10.1111/apha.13792

N/A

0DataRank · unranked

0 citations

Mark Donowitz

SLC26A3 (DRA) is stimulated in a synergistic, intracellular Ca 2+ dependent manner by cAMP AND ATP in intestinal epithelial cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.02.518884

N/A

0DataRank · unranked

0 citations

Ruxian Lin, Varsha Singh, Mark Donowitz, Chung‐Ming Tse, Rafiquel Sarker

Air-Liquid-Interface Reorganizes Membrane Lipid and Enhance Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colon

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.22.521645

N/A

0DataRank · unranked

0 citations

Yan Rong, Zixin Zhang, Ruxian Lin, Rafiq Sarker, Mark Donowitz +2 more

A Novel Peptide Prevents Enterotoxin- and Inflammation-Induced Intestinal Fluid Secretion by Stimulating Sodium-Hydrogen Exchanger 3 Activity

Gastroenterology(2023)10.1053/j.gastro.2023.06.028

N/A

0DataRank · unranked

3 citations

Hannah J. Vaughan, Ruxian Lin, Rafiquel Sarker, Savannah Est‐Witte, Molee Chakraborty +8 more

Disruption of Epithelium Integrity by Inflammation-Associated Fibroblasts through Prostaglandin Signaling

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.28.560060

N/A

0DataRank · unranked

1 citations

Blake A. Johnson, Linhao Ruan, Maged Zeineldin, Albert Z. Liu, Sumana Raychaudhuri +10 more

Human enteroid monolayers: A novel, functionally stable model for investigating oral drug disposition

Drug Metabolism and Disposition(2024)10.1124/dmd.124.001551

N/A

0DataRank · unranked

13 citations

Eimear T O'Mahony, James W. MacDonald, Theo K. Bammler, Mark Donowitz, Edward J. Kelly +2 more

Type 1 diabetes human enteroid studies reveal major changes in the intestinal epithelial compartment

Scientific Reports(2024)10.1038/s41598-024-62282-x

N/A

0DataRank · unranked

7 citations

Yan Rong, Zixin Zhang, Ruxian Lin, Anthony L. Guerrerio, Chung‐Ming Tse +3 more

COVID-19 Diarrhea Is Inflammatory, Caused by Direct Viral Effects Plus Major Role of Virus-induced Cytokines

Cellular and Molecular Gastroenterology and Hepatology(2024)10.1016/j.jcmgh.2024.101383

N/A

0DataRank · unranked

1 citations

Chung-Ming Tse, Rafiq Sarker, Ruxian Lin, Karol Dokładny, Manmeet Rawat +18 more

Host-derived CEACAM-laden vesicles engage enterotoxigenic E. coli for elimination and toxin neutralization

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.24.604983

N/A

0DataRank · unranked

1 citations

Debayan Ganguli, Tim Vickers, Bernhard B. Singer, Jennifer Foulke‐Abel, Marjahan Akhtar +12 more

Partially differentiated ileal and distal-colonic human F508del-cystic fibrosis-enteroids secrete fluid in response to forskolin and linaclotide

iScience(2025)10.1016/j.isci.2025.112453

N/A

0DataRank · unranked

4 citations

Zixin Zhang, Hugo R. de Jonge, Ruxian Lin, Huimin Yu, Rafiq Sarker +7 more

Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease

JCI Insight(2020)10.1172/jci.insight.140978

N/A

0DataRank · unranked

58 citations

Azra Frkatović-Hodžić, Sodbo Sharapov, Qinchuan Wang, Heather M. Neu, Xinqun Wu +10 more

Differential Regulation of NHE3 Expression in Type 1 and Type 2 Diabetic Intestine: Impaired Endosomal Regulation of NHE3 Expression in Type 1 Diabetes

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.10.675364

N/A

0DataRank · unranked

0 citations

Ruxian Lin, Laxmi Sunuwar, Jianbo Yang, Mark Donowitz, Rafiquel Sarker +1 more

Current and potential future applications of human stem cell models in drug development

Journal of Clinical Investigation(2020)10.1172/jci138645

N/A

0DataRank · unranked

20 citations

Jerrold R. Turner, A.S. Verkman, Nicholas C. Zachos, Mark Donowitz

Chronic exposure of ErbB TKIs inhibits DRA expression and activity through an ERK/Elk-1/CREB/AP-1 dependent pathway

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.16.342139

N/A

0DataRank · unranked

0 citations

Ru-Xian Lin, Rafiquel Sarker, Mark Donowitz, Hong Woon Yang

Elevated Intracellular Calcium Stimulates NHE3 Activity by an IKEPP (NHERF4) Dependent Mechanism

UNC Libraries(2020)10.17615/4dvc-1y89

N/A

0DataRank · unranked

0 citations

Boyoung Cha, William R. Thelin, Xuhang Li, Nicholas C. Zachos, Caleb A. Hodson +3 more

Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell Function

Cellular and Molecular Gastroenterology and Hepatology(2021)10.1016/j.jcmgh.2021.08.010

N/A

0DataRank · unranked

82 citations

Kelli Johnson, Jianyi Yin, Sun Lee, Ruxian Lin, Huimin Yu +6 more

Patients' perspectives on the derivation and use of organoids

Stem Cell Reports(2021)10.1016/j.stemcr.2021.07.004

N/A

0DataRank · unranked

52 citations

Elizabeth May, Debra Mathews, Mark Donowitz, Jeremy Sugarman, Juli Bollinger

SARS-COV-2 induced Diarrhea is inflammatory, Ca 2+ Dependent and involves activation of calcium activated Cl channels

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.27.441695

N/A

0DataRank · unranked

1 citations

Chung-Ming Tse, Karol Dokładny, Manmeet Rawat, Ivy Horwitz, Chunyan Ye +12 more

Identification of Intestinal NaCl Absorptive-Anion Secretory Cells: Potential Functional Significance

Frontiers in Physiology(2022)10.3389/fphys.2022.892112

N/A

0DataRank · unranked

14 citations

Rafiquel Sarker, Ruxian Lin, George McNamara, Chung‐Ming Tse, Varsha Singh +1 more

Adipokine C1q/Tumor Necrosis Factor- Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation Via Sirtuin 1/NF-κB Signaling

Cellular and Molecular Gastroenterology and Hepatology(2022)10.1016/j.jcmgh.2022.12.013

N/A

0DataRank · unranked

11 citations

Zixin Zhang, Gangping Li, Yan Feng, Lingling Xian, Fatemeh Bakhsh +9 more