Wenyi Wei

Also affiliated with Harvard University, Hadassah Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 64 papers. Top paper: “Cancer Selective Target Degradation by Folate-Caged PROTACs”.

Cancer Selective Target Degradation by Folate-Caged PROTACs

Journal of the American Chemical Society(2021)10.1021/jacs.1c00451

N/A

8.4DataRank · unranked

292 citations

He Chen, Yi Liu, Yudao Shen, Fanye Meng, H. Ümit Kanıskan +3 more

Inhibition of HECT E3 ligases as potential therapy for COVID-19

Cell Death and Disease(2021)10.1038/s41419-021-03513-1

N/A

1.5DataRank · unranked

57 citations

Jing Liu, Michela Biancolella, Tonino Alonzi, Antonio Novelli, J. J. Patten +38 more

Cell cycle on the crossroad of tumorigenesis and cancer therapy

Trends in Cell Biology(2021)10.1016/j.tcb.2021.07.001

N/A

0.889DataRank · unranked

373 citations

Yunhua Peng, Wenyi Wei, Jing Liu

Ubiquitin signaling in cell cycle control and tumorigenesis

Cell Death and Differentiation(2020)10.1038/s41418-020-00648-0

N/A

0.888DataRank · unranked

372 citations

Li Nie, Wenyi Wei, Fabin Dang

Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

Cell Research(2020)10.1038/s41422-020-0372-z

N/A

0.718DataRank · unranked

119 citations

Yunhua Peng, Le Shi, Lixin Wan, Hiroyuki Inuzuka, Jiangang Long +14 more

Folate-Guided Protein Degradation by Immunomodulatory Imide Drug-Based Molecular Glues and Proteolysis Targeting Chimeras

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00901

N/A

0.712DataRank · unranked

114 citations

Jing Liu, H. Ümit Kanıskan, Wenyi Wei, Jian Jin, He Chen

PROTAC technology for the treatment of Alzheimer’s disease: advances and perspectives

Acta Materia Medica(2022)10.15212/amm-2021-0001

N/A

0.581DataRank · unranked

47 citations

Jing Liu, Wenyi Wei, Abdol-Hossein Rezaeian, Hiroyuki Inuzuka

Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-21-0147

N/A

0.568DataRank · unranked

43 citations

Jianping Guo, Karin A. Vallega, C. Hu, Zhen Chen, Yunfu Deng +7 more

Biochemical Aspects of PD-L1 Regulation in Cancer Immunotherapy

Trends in Biochemical Sciences(2019)10.1016/j.tibs.2019.03.004

N/A

0.553DataRank · unranked

39 citations

Fabin Dang, Junming Ren, Wenyi Wei, Jinfang Zhang

USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK

Journal of the American Chemical Society(2024)10.1021/jacs.4c02373

N/A

0.515DataRank · unranked

30 citations

Xiaoping Hu, Kaixiu Luo, Yan Xiong, Li Chen, Zhen Wang +11 more

Regulation of neuronal autophagy and cell survival by MCL1 in Alzheimer’s disease

Acta Materia Medica(2022)10.15212/amm-2021-0002

N/A

0.500DataRank · unranked

27 citations

Wenyi Wei, Hiroyuki Inuzuka, Abdol-Hossein Rezaeian

Acetylation-dependent regulation of BRAF oncogenic function

Cell Reports(2022)10.1016/j.celrep.2021.110250

N/A

0.483DataRank · unranked

24 citations

Xiaoling Zhang, Qing Yin, Jia Hu, Jianping Guo, Yang Gao +5 more

O-GlcNAcylation in tumorigenesis and its implications for cancer therapy

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107709

N/A

0.483DataRank · unranked

24 citations

Yihang Qi, Hiroyuki Inuzuka, Jing Liu, Wenyi Wei, Dize Zhang

WWP1 inactivation enhances efficacy of PI3K inhibitors while suppressing their toxicities in breast cancer models

Journal of Clinical Investigation(2021)10.1172/jci140436

N/A

0.470DataRank · unranked

22 citations

Hiroshi Higuchi, Limei Wang, Nivedita Panch, Valerie Maymi, Sachem Best +12 more

USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice

Science Translational Medicine(2023)10.1126/scitranslmed.adh7668

N/A

0.449DataRank · unranked

19 citations

Lei Bai, Jiazhen Dong, Xiaoping Hu, Jingchao Wang, Joao A. Paulo +22 more

Identification of a distal enhancer regulating hedgehog interacting protein gene in human lung epithelial cells

EBioMedicine(2024)10.1016/j.ebiom.2024.105026

N/A

0.360DataRank · unranked

10 citations

Li Zhang, Yuzhen Yu, Lu Gong, Shiyue Tao, Rhiannon B. Werder +17 more

Targeting the PRMT1-cGAS-STING signaling pathway to enhance the anti-tumor therapeutic efficacy

Journal of Cancer Biology(2024)10.46439/cancerbiology.5.064

N/A

0.330DataRank · unranked

8 citations

Abdol-Hossein Rezaeian, Jingchao Wang, Yihang Qi, Hong Chen, Hiroyuki Inuzuka +2 more

Deubiquitinase-Targeting Chimeras Mediated Stabilization of Tumor Suppressive E3 Ligase Proteins as a Strategy for Cancer Therapy

Journal of the American Chemical Society(2025)10.1021/jacs.5c06306

N/A

0.312DataRank · unranked

7 citations

Zhijie Deng, Yan Xiong, Jing Liu, Daoyuan Huang, Jingchao Wang +7 more

PROTAC technology for prostate cancer treatment

Acta Materia Medica(2025)10.15212/amm-2024-0075

N/A

0.312DataRank · unranked

7 citations

Dingpeng Zhang, Hiroyuki Inuzuka, Wenyi Wei, Zhen Wang

Targeting the PARylation-Dependent Ubiquitination Signaling Pathway for Cancer Therapies

Biomolecules(2025)10.3390/biom15020237

N/A

0.312DataRank · unranked

7 citations

Jingchao Wang, Li Chen, Weiwei Jiang, Hiroyuki Inuzuka, David K. Simon +2 more

New Insights into Protein Hydroxylation and Its Important Role in Human Diseases

UNC Libraries(2020)10.17615/myjq-3b95

N/A

0.241DataRank · unranked

4 citations

Wenyi Wei, Giada Zurlo, Jianping Guo, Qing Zhang, Mamoru Takada

Inactivation of Minar2 in mice hyperactivates mTOR signaling and results in obesity

Molecular Metabolism(2023)10.1016/j.molmet.2023.101744

N/A

0.241DataRank · unranked

4 citations

Chaoshuang Xia, Razie Amraei, Hua Ning, Konstantin V. Kandror, Stephen R. Farmer +5 more

HHIP protein interactions in lung cells provide insight into COPD pathogenesis

Human Molecular Genetics(2025)10.1093/hmg/ddaf016

N/A

0.208DataRank · unranked

3 citations

Hiroyuki Inuzuka, Peter J. Castaldi, Jeong H. Yun, Zhonghui Xu, Wardatul Jannat Anamika +7 more

Methylated Nucleotide-Based Proteolysis-Targeting Chimera Enables Targeted Degradation of Methyl-CpG-Binding Protein 2

Journal of the American Chemical Society(2023)10.1021/jacs.3c06023

N/A

0DataRank · unranked

13 citations

Jing Liu, Xing Qiu, Dingpeng Zhang, Hiroyuki Inuzuka, Li Chen +7 more

PROTACs targeting epigenetic proteins

Acta Materia Medica(2023)10.15212/amm-2023-0039

N/A

0DataRank · unranked

9 citations

Yuna He, Xiuyun Sun, Wenyi Wei, Yanlong Liu, Yu Rao +1 more

AKT Phosphorylates FAM13A and Promotes Its Degradation via CUL4A/DDB1/DCAF1 E3 Complex

American Journal of Respiratory Cell and Molecular Biology(2023)10.1165/rcmb.2022-0362oc

N/A

0DataRank · unranked

8 citations

Samuel Bates, Yujun Li, Xin Lin, Wenyi Wei, Xiaobo Zhou +1 more

Lactate fuels mitosis

Molecular Cell(2023)10.1016/j.molcel.2023.04.013

N/A

0DataRank · unranked

0 citations

Wenyi Wei, Xiaoming Dai

The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis

Science Immunology(2024)10.1126/sciimmunol.adn1452

N/A

0DataRank · unranked

183 citations

Alan Y. Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana +19 more

Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1

Journal of the American Chemical Society(2024)10.1021/jacs.3c13646

N/A

0DataRank · unranked

30 citations

Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu +8 more

Nutrient sensing of mTORC1 signaling in cancer and aging

Seminars in Cancer Biology(2024)10.1016/j.semcancer.2024.08.001

N/A

0DataRank · unranked

29 citations

Xiao Tan, Ning Liu, Peiqiang Yan, Tao Hou, Wenyi Wei +1 more

Molecular insights and clinical implications for the tumor suppressor role of SCFFBXW7 E3 ubiquitin ligase

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer(2024)10.1016/j.bbcan.2024.189140

N/A

0DataRank · unranked

22 citations

Abdol-Hossein Rezaeian, Jingchao Wang, Daoyuan Huang, Hong Chen, Hiroyuki Inuzuka +2 more

The First‐In‐Class Deubiquitinase‐Targeting Chimera Stabilizes and Activates cGAS

Angewandte Chemie International Edition(2024)10.1002/anie.202415168

N/A

0DataRank · unranked

20 citations

Li Chen, Chao Qian, Jing Liu, Qiong Wu, Xiangyang Song +12 more

Application of PROTACs in target identification and validation

Acta Materia Medica(2024)10.15212/amm-2024-0010

N/A

0DataRank · unranked

18 citations

Jing Liang, Rui Zhu, Yueying Yang, Yali Wang, Wenyi Wei +3 more

Targeted Degradation of Receptor-Interacting Protein Kinase 1 to Modulate the Necroptosis Pathway

ACS Pharmacology & Translational Science(2024)10.1021/acsptsci.4c00421

N/A

0DataRank · unranked

6 citations

Chao Qian, Yihang Qi, Yan Xiong, Chaoyu Wang, Zhen Wang +5 more

Molecular signaling and clinical implications in the human aging-cancer cycle

Seminars in Cancer Biology(2024)10.1016/j.semcancer.2024.08.003

N/A

0DataRank · unranked

2 citations

Wenyi Wei, Abdol-Hossein Rezaeian

Identification of PLK1 as the Target of Tubocapsenolide A for the Activation of Colorectal Cancer Ferroptosis by PROTAC Technology

ChemRxiv(2024)10.26434/chemrxiv-2024-0gmkw

N/A

0DataRank · unranked

2 citations

Yang Liu, Lu Wang, Jing Liang, Hongyan Zhang, Zhiruo Zhang +12 more

Interplay Between FoxM1 and Dab2 Promotes Endothelial Cell Responses in Diabetic Wound Healing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.07.579019

N/A

0DataRank · unranked

0 citations

Jianing Gao, Yao Wei Lu, Shahram Eisa-Beygi, Hao Wu, Kathryn Li +10 more

USP28-Based Deubiquitinase-Targeting Chimeras for Cancer Treatment

Journal of the American Chemical Society(2025)10.1021/jacs.5c01889

N/A

0DataRank · unranked

19 citations

C. D. Qian, Yan Xiong, Dingpeng Zhang, Hiroyuki Inuzuka, Yue Zhong +5 more

Harnessing the Deubiquitinase USP1 for Targeted Protein Stabilization

Journal of the American Chemical Society(2025)10.1021/jacs.5c01662

N/A

0DataRank · unranked

13 citations

Zhen Wang, Yan Xiong, Dingpeng Zhang, Yue Zhong, Hiroyuki Inuzuka +6 more

Dual membrane receptor degradation via folate receptor targeting chimera

Nature Communications(2025)10.1038/s41467-025-63882-5

N/A

0DataRank · unranked

10 citations

Zhixin Li, Jenny Högström, Hiroyuki Inuzuka, Rui Jing, Peiqiang Yan +11 more

Targeting the cell-cycle machinery for cancer therapy

Trends in Cell Biology(2025)10.1016/j.tcb.2025.08.008

N/A

0DataRank · unranked

4 citations

Jiejing Liu, Hiroyuki Inuzuka, Wenyi Wei, Jing Liu, Yunhua Peng

Molecular Subtypes and Targeted Therapeutic Strategies in Small Cell Lung Cancer: Advances, Challenges, and Future Perspectives

Molecules(2025)10.3390/molecules30081731

N/A

0DataRank · unranked

18 citations

Jingchao Wang, Li Chen, Weiwei Jiang, Hiroyuki Inuzuka, David K. Simon +2 more

WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition

New England Journal of Medicine(2020)10.1056/nejmoa1914919

N/A

0DataRank · unranked

79 citations

Lamis Yehia, Takahiro Kishikawa, Ying Ni, Brandie Heald, Jinfang Zhang +6 more

The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance

Cell Reports(2020)10.1016/j.celrep.2020.108102

N/A

0DataRank · unranked

15 citations

Yanwen Shen, Hua Li, Chao Bi, Yilun Sun, Xiufang Xiong +3 more

FAM13A Represses AMPK Activity and Regulates Hepatic Glucose and Lipid Metabolism

iScience(2020)10.1016/j.isci.2020.100928

N/A

0DataRank · unranked

24 citations

Yae-Huei Liou, Yujun Li, Lu Gong, Yan Li, Yuan Hao +13 more

pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner

UNC Libraries(2020)10.17615/792d-1w31

N/A

0DataRank · unranked

4 citations

Jinfang Zhang, Hiroyuki Inuzuka, Xingnan Zheng, Wenjian Gan, Abhishek A. Chakraborty +13 more

TF-PROTACs Enable Targeted Degradation of Transcription Factors

Journal of the American Chemical Society(2021)10.1021/jacs.1c03852

N/A

0DataRank · unranked

233 citations

He Chen, H. Ümit Kanıskan, Ling Xie, Xian Chen, Jian Jin +2 more

Targeting the acetylation signaling pathway in cancer therapy

Seminars in Cancer Biology(2021)10.1016/j.semcancer.2021.03.001

N/A

0DataRank · unranked

104 citations

Wenyi Wei, Fabin Dang

Post-translational regulations of PD-L1 and PD-1: Mechanisms and opportunities for combined immunotherapy

Seminars in Cancer Biology(2021)10.1016/j.semcancer.2021.04.002

N/A

0DataRank · unranked

73 citations

Yang Gao, Wenyi Wei, Xiaoming Dai

Interplay between protein acetylation and ubiquitination controls MCL1 protein stability

Cell Reports(2021)10.1016/j.celrep.2021.109988

N/A

0DataRank · unranked

61 citations

Min Gi, Shugo Suzuki, Brian J. North, Asami Watahiki, Satoshi Fukumoto +5 more

Light-Controllable PROTACs for Temporospatial Control of Protein Degradation

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.678077

N/A

0DataRank · unranked

37 citations

Yunhua Peng, Wenyi Wei, Jing Liu

USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy

Nature Communications(2022)10.1038/s41467-022-29401-6

N/A

0DataRank · unranked

152 citations

Xueliang Gao, Tiantian Zhang, Baishan Jiang, Mingming Hu, Xia Bu +18 more

Necroptosis pathways in tumorigenesis

Seminars in Cancer Biology(2022)10.1016/j.semcancer.2022.07.007

N/A

0DataRank · unranked

92 citations

Yingnan Wang, Hiroyuki Inuzuka, Wenyi Wei, Tao Zhang

PROTAC degraders with ligands recruiting MDM2 E3 ubiquitin ligase: an updated perspective

Acta Materia Medica(2022)10.15212/amm-2022-0010

N/A

0DataRank · unranked

65 citations

Wenyi Wei, Yi Sun, Xin Han

TF-DUBTACs Stabilize Tumor Suppressor Transcription Factors

Journal of the American Chemical Society(2022)10.1021/jacs.2c04824

N/A

0DataRank · unranked

61 citations

Xufen Yu, He Chen, H. Ümit Kanıskan, Ling Xie, Xian Chen +3 more

Ring domains are essential for GATOR2-dependent mTORC1 activation

Molecular Cell(2022)10.1016/j.molcel.2022.11.021

N/A

0DataRank · unranked

33 citations

Xiaoming Dai, Shaohui He, Hongfei Zhou, Lan Fang, Jianping Guo +11 more

Targeting micro-environmental pathways by PROTACs as a therapeutic strategy

Seminars in Cancer Biology(2022)10.1016/j.semcancer.2022.07.001

N/A

0DataRank · unranked

18 citations

Yunhua Peng, Hiroyuki Inuzuka, Wenyi Wei, Jing Liu

Insights into the aberrant CDK4/6 signaling pathway as a therapeutic target in tumorigenesis

Advances in protein chemistry and structural biology(2022)10.1016/bs.apcsb.2022.11.009

N/A

0DataRank · unranked

12 citations

Hiroyuki Inuzuka, Wenyi Wei, Abdol-Hossein Rezaeian

Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1

Science(2023)10.1126/science.abn1725

N/A

0DataRank · unranked

123 citations

Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song +35 more

Targeted protein posttranslational modifications by chemically induced proximity for cancer therapy

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104572

N/A

0DataRank · unranked

61 citations

Jing Liu, Hiroyuki Inuzuka, Wenyi Wei, Yunhua Peng

Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation

Nature Cell Biology(2023)10.1038/s41556-023-01170-4

N/A

0DataRank · unranked

61 citations

Daichao Xu, Jianping Liu, Min Wang, Li‐Juan Duan, Min Liu +34 more

AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation

Nature Metabolism(2023)10.1038/s42255-022-00732-4

N/A

0DataRank · unranked

41 citations

Cong Jiang, Qiwei Jiang, Lan Fang, Haihong Yu, Jinhe Guo +9 more

PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2

Cell Metabolism(2023)10.1016/j.cmet.2023.11.001

N/A

0DataRank · unranked

39 citations

Jing Liu, Shaohui He, Wei Xu, Runzhi Huang, Weijuan Pan +10 more

Telomere Targeting Chimera Enables Targeted Destruction of Telomeric Repeat-Binding Factor Proteins

Journal of the American Chemical Society(2023)10.1021/jacs.3c02783

N/A

0DataRank · unranked

30 citations

Jing Liu, He Chen, Xing Qiu, Ling Xie, H. Ümit Kanıskan +4 more