Chase L. Beisel

Also affiliated with Helmholtz Centre for Infection Research, Helmholtz Institute for RNA-based Infection Research, Institute of Molecular and Clinical Ophthalmology Basel

Biochemistry, Genetics and Molecular BiologyAgricultural and Biological Sciences

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 16 papers. Top paper: “Spacer prioritization in CRISPR–Cas9 immunity is enabled by the leader RNA”.

Spacer prioritization in CRISPR–Cas9 immunity is enabled by the leader RNA

Nature Microbiology(2022)10.1038/s41564-022-01074-3

N/A

0.500DataRank · unranked

27 citations

Sahil Sharma, Sarah L. Svensson, Anuja Kibe, Zasha Weinberg, Omer S. Alkhnbashi +6 more

Expanding the flexibility of base editing for high-throughput genetic screens in bacteria

Nucleic Acids Research(2024)10.1093/nar/gkae174

N/A

0.430DataRank · unranked

9 citations

Scott P. Collins, Yanying Yu, Samuel A Blackman, Lars Barquist, Chase L. Beisel +1 more

Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems

PLoS ONE(2020)10.1371/journal.pone.0232046

N/A

0.393DataRank · unranked

6 citations

Gloria Yi, Hadel Al Asafen, Ashley Jermusyk, Chase L. Beisel, Gregory T. Reeves +1 more

CRISPR technologies and the search for the PAM-free nuclease

Nature Communications(2021)10.1038/s41467-020-20633-y

N/A

0DataRank · unranked

304 citations

Chase L. Beisel, Daphne Collias

In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii

ACS Synthetic Biology(2021)10.1021/acssynbio.0c00562

N/A

0DataRank · unranked

78 citations

Yi-Hui Zhou, Scott P. Collins, Junrui Cheng, Abdulkerim Eroglu, Chase L. Beisel +2 more

Sequence-independent RNA sensing and DNA targeting by a split domain CRISPR–Cas12a gRNA switch

Nucleic Acids Research(2021)10.1093/nar/gkab100

N/A

0DataRank · unranked

57 citations

William Rostain, Chunyu Liao, Chase L. Beisel, Scott P. Collins

A target expression threshold dictates invader defense and autoimmunity by CRISPR-Cas13

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.23.469693

N/A

0DataRank · unranked

4 citations

Yanying Yu, Scott P. Collins, Katharina G. Wandera, Lars Barquist, Chase L. Beisel +1 more

Characterization of Cas12a nucleases reveals diverse PAM profiles between closely-related orthologs

Nucleic Acids Research(2020)10.1093/nar/gkaa272

N/A

0DataRank · unranked

57 citations

Fani Ttofali, Chunyu Liao, Srinivas Manchalu, Benjamin N. Gray, Chase L. Beisel +1 more

Large-scale structural rearrangements unleash indiscriminate nuclease activity of CRISPR-Cas12a2

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.13.495754

N/A

0DataRank · unranked

2 citations

Thom Hallmark, Bronson Naegle, Chase L. Beisel, Ryan N. Jackson, David W. Taylor +1 more

RNA targeting unleashes indiscriminate nuclease activity of CRISPR–Cas12a2

Nature(2023)10.1038/s41586-022-05560-w

N/A

0DataRank · unranked

80 citations

Thomson Hallmark, Bronson Naegle, Chase L. Beisel, Ryan N. Jackson, David W. Taylor +1 more

Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA

Nature(2023)10.1038/s41586-022-05559-3

N/A

0DataRank · unranked

75 citations

Gina C. Neumann, Thomson Hallmark, Dylan Keiser, Valerie M. Crowley, Elena Vialetto +11 more

An updated evolutionary classification of CRISPR–Cas systems including rare variants

Nature Microbiology(2025)10.1038/s41564-025-02180-8

N/A

0DataRank · unranked

60 citations

Sergey Shmakov, Yuri I. Wolf, Pascal Mutz, Han Altae-Tran, Chase L. Beisel +24 more

Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes

Nature Biotechnology(2025)10.1038/s41587-025-02802-w

N/A

0DataRank · unranked

3 citations

Constantinos Patinios, Harris V. Bassett, Anuja Kibe, Scott P. Collins, Charlotte Kamm +21 more

A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13

Cell Host & Microbe(2022)10.1016/j.chom.2022.05.013

N/A

0DataRank · unranked

31 citations

Yanying Yu, Scott P. Collins, Katharina G. Wandera, Lars Barquist, Chase L. Beisel +1 more

A positive, growth-based PAM screen identifies noncanonical motifs recognized by the S. pyogenes Cas9

Science Advances(2020)10.1126/sciadv.abb4054

N/A

0DataRank · unranked

27 citations

Ryan T. Leenay, Rebecca Slotkowski, Zhicheng Zuo, Scott P. Collins, B. A. McGirr +3 more

Your Base Editor Might Be Flirting with Single (Stranded) DNA: Faithful On-Target CRISPR Base Editing without Promiscuous Deamination

Molecular Cell(2020)10.1016/j.molcel.2020.07.030

N/A

0DataRank · unranked

2 citations

Chase L. Beisel, Scott P. Collins