Yan Xiong

Fujian Agriculture and Forestry University

Agricultural and Biological SciencesBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 41 papers. Top paper: “Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets”.

Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets

Journal of the American Chemical Society(2022)10.1021/jacs.2c09255

N/A

0.736DataRank · unranked

134 citations

Yue Zhong, Hyerin Yim, Xiaobao Yang, Kwang‐Su Park, Ling Xie +7 more

Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis

Cancer Discovery(2020)10.1158/2159-8290.cd-19-0532

N/A

0.646DataRank · unranked

73 citations

Qing Yu Weng, Megan L. Insco, Kevin Y. Chen, Sathya Muralidhar, Joanna Poźniak +18 more

The gut-reproductive axis: Bridging microbiota balances to reproductive health and fetal development

International Immunopharmacology(2025)10.1016/j.intimp.2024.113627

N/A

0.623DataRank · unranked

29 citations

Yan Xiong, Dong Guo, Guohong Deng, Haibo Wu, Bohao Li

MEF2D sustains activation of effector Foxp3+ Tregs during transplant survival and anticancer immunity

Journal of Clinical Investigation(2020)10.1172/jci135486

N/A

0.533DataRank · unranked

34 citations

Liqing Wang, Yan Xiong, Tatiana Akimova, Lanette M. Christensen, Rongxiang Han +6 more

USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK

Journal of the American Chemical Society(2024)10.1021/jacs.4c02373

N/A

0.515DataRank · unranked

30 citations

Xiaoping Hu, Kaixiu Luo, Yan Xiong, Li Chen, Zhen Wang +11 more

Newly developed oral bioavailable EHMT2 inhibitor as a potential epigenetic therapy for Prader-Willi syndrome

Molecular Therapy(2024)10.1016/j.ymthe.2024.05.034

N/A

0.508DataRank · unranked

14 citations

Yan Xiong, Mi‐Ae Jang, Kwang‐Su Park, Meaghan Donahue, Julia Velez +3 more

Sulfate‐TOR signaling controls transcriptional reprogramming for shoot apex activation

New Phytologist(2022)10.1111/nph.18441

N/A

0.477DataRank · unranked

23 citations

Zhaochen Zhong, Liuyin Ma, Chengbin Xiang, Jie Chen, Xin‐Yuan Huang +3 more

Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation

Cell chemical biology(2023)10.1016/j.chembiol.2023.09.012

N/A

0.434DataRank · unranked

17 citations

Li Wang, Ling Xie, Feng Zhang, Bing Wu, Mei Liu +15 more

Calpain activity is negatively regulated by a KCTD7–Cullin-3 complex via non-degradative ubiquitination

Cell Discovery(2023)10.1038/s41421-023-00533-3

N/A

0.385DataRank · unranked

12 citations

Shalaka Mulherkar, Uan-I Chen, Yan Xiong, Lakshya Bajaj, Byoung-Kyu Cho +5 more

Design, Synthesis, and Evaluation of p53Y220C Acetylation Targeting Chimeras (AceTACs)

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01497

N/A

0.330DataRank · unranked

8 citations

Md Kabir, Yindan Lin, Yan Xiong, Ramon Parsons, Wei Gu +2 more

Deubiquitinase-Targeting Chimeras Mediated Stabilization of Tumor Suppressive E3 Ligase Proteins as a Strategy for Cancer Therapy

Journal of the American Chemical Society(2025)10.1021/jacs.5c06306

N/A

0.312DataRank · unranked

7 citations

Zhijie Deng, Yan Xiong, Jing Liu, Daoyuan Huang, Jingchao Wang +7 more

Targeting G9a-m6A translational mechanism of SARS-CoV-2 pathogenesis for multifaceted therapeutics of COVID-19 and its sequalae

iScience(2025)10.1016/j.isci.2025.112632

N/A

0.165DataRank · unranked

2 citations

Ling Xie, Xuping Xie, Feng Zhang, John A. Wrobel, Yan Xiong +11 more

Bitter taste receptor activation by cholesterol and an intracellular tastant

Nature(2024)10.1038/s41586-024-07253-y

N/A

0DataRank · unranked

91 citations

Ryan H. Gumpper, Yongfeng Liu, D. Dewran Koçak, Yan Xiong, Can Cao +7 more

Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1

Journal of the American Chemical Society(2024)10.1021/jacs.3c13646

N/A

0DataRank · unranked

30 citations

Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu +8 more

The First‐In‐Class Deubiquitinase‐Targeting Chimera Stabilizes and Activates cGAS

Angewandte Chemie International Edition(2024)10.1002/anie.202415168

N/A

0DataRank · unranked

20 citations

Li Chen, Chao Qian, Jing Liu, Qiong Wu, Xiangyang Song +12 more

Discovery of the First-in-Class G9a/GLP PROTAC Degrader

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.3c02394

N/A

0DataRank · unranked

12 citations

Yulin Han, Hyerin Yim, Peiyi Yang, Zhijie Deng, Kwang‐Su Park +5 more

Discovery and Characterization of a Novel Cereblon-Recruiting PRC1 Bridged PROTAC Degrader

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00538

N/A

0DataRank · unranked

11 citations

Lihuai Qin, Kaixiu Luo, Yan Xiong, Rebecca A. Sidi, Kwang‐Su Park +2 more

Targeted Degradation of Receptor-Interacting Protein Kinase 1 to Modulate the Necroptosis Pathway

ACS Pharmacology & Translational Science(2024)10.1021/acsptsci.4c00421

N/A

0DataRank · unranked

6 citations

Chao Qian, Yihang Qi, Yan Xiong, Chaoyu Wang, Zhen Wang +5 more

Harnessing the TAF1 Acetyltransferase for Targeted Acetylation of the Tumor Suppressor p53

Advanced Science(2024)10.1002/advs.202413377

N/A

0DataRank · unranked

6 citations

Xiaoping Hu, Tiphaine Martin, Dmitry Pokushalov, Yong Joon Kim, Yiyang Chen +9 more

Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00121

N/A

0DataRank · unranked

3 citations

Holger Greschik, C. Johansson, Ludwig Seifert, Vicki Gamble, Kwang‐Su Park +14 more

Targeting G9a translational mechanism of SARS-CoV-2 pathogenesis for multifaceted therapeutics of COVID-19 and its sequalae

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.04.583415

N/A

0DataRank · unranked

0 citations

Ling Xie, Xuping Xie, Feng Zhang, John A. Wrobel, Yan Xiong +11 more

Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation

UNC Libraries(2024)10.17615/144y-5d10

N/A

0DataRank · unranked

0 citations

Kanishk Jain, Ling Xie, Erik M. Lenarcic, Feng Zhang, Hongjun Song +15 more

USP28-Based Deubiquitinase-Targeting Chimeras for Cancer Treatment

Journal of the American Chemical Society(2025)10.1021/jacs.5c01889

N/A

0DataRank · unranked

19 citations

C. D. Qian, Yan Xiong, Dingpeng Zhang, Hiroyuki Inuzuka, Yue Zhong +5 more

Harnessing the Deubiquitinase USP1 for Targeted Protein Stabilization

Journal of the American Chemical Society(2025)10.1021/jacs.5c01662

N/A

0DataRank · unranked

13 citations

Zhen Wang, Yan Xiong, Dingpeng Zhang, Yue Zhong, Hiroyuki Inuzuka +6 more

Harnessing the SPOP E3 Ubiquitin Ligase via a Bridged Proteolysis Targeting Chimera (PROTAC) Strategy for Targeted Protein Degradation

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00295

N/A

0DataRank · unranked

12 citations

Jerrel L. Catlett, Youngeun Lee, Qiong Wu, Zhongli Xu, Ling Xie +5 more

Discovery of an LSD1 PROTAC degrader

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2425812122

N/A

0DataRank · unranked

11 citations

Xing Qiu, Yan Xiong, Karen Chiang, Jerrel L. Catlett, Ines H. Kaltheuner +5 more

Discovery of a Potent and Selective Protein Arginine Methyltransferase 5 (PRMT5) PROTAC Degrader

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00198

N/A

0DataRank · unranked

9 citations

Huensuk Kim, Chao Qian, Ling Xie, Xian Chen, Yan Xiong +6 more

Discovery of the first-in-class Aurora B kinase selective degrader

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.118006

N/A

0DataRank · unranked

1 citations

Kevin Graciano, Jianping Hu, Chang Liu, Jiuyi Zhang, Ling Xie +5 more

Differential effects of HDAC8 targeting on Foxp3+ Tregs and effector T cells promote antitumor immunity

JCI Insight(2025)10.1172/jci.insight.186461

N/A

0DataRank · unranked

0 citations

Yan Xiong, Liqing Wang, Rongxiang Han, Hossein Fazelinia, Jennifer Roof +4 more

Structure–Activity Relationship Studies of DNA Methyltransferase 1 Monovalent Degraders

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c02161

N/A

0DataRank · unranked

5 citations

Youngeun Lee, Yulin Han, Yue Zhong, Jujun Zhou, Joel Hrit +9 more

Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity

Journal of Clinical Investigation(2020)10.1172/jci131375

N/A

0DataRank · unranked

72 citations

Liqing Wang, Eros Di Giorgio, Tatiana Akimova, Ulf H. Beier, Rongxiang Han +5 more

Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.14.382416

N/A

0DataRank · unranked

22 citations

Adil Muneer, Ling Xie, Feng Zhang, Bing Wu, Mei Liu +15 more

Distinct CDK6 complexes determine tumor cell response to CDK4/6 inhibitors and degraders

Nature Cancer(2021)10.1038/s43018-021-00174-z

N/A

0DataRank · unranked

73 citations

Xiaobao Yang, Yan Xiong, Ruitong Li, Takahiro Ito, Tamer A. Ahmed +14 more

Gq signaling in α cells is critical for maintaining euglycemia

JCI Insight(2021)10.1172/jci.insight.152852

N/A

0DataRank · unranked

26 citations

Diptadip Dattaroy, Katherine F. Simpson, Luiz F. Barella, Yinghong Cui, Yan Xiong +8 more

A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells

Frontiers in Immunology(2021)10.3389/fimmu.2021.703632

N/A

0DataRank · unranked

14 citations

Liqing Wang, Yan Xiong, Lanette M. Christensen, Tatiana Akimova, Rongxiang Han +6 more

Discovery of the First-in-Class G9a/GLP Covalent Inhibitors

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00652

N/A

0DataRank · unranked

46 citations

Yan Xiong, Hyerin Yim, Julia Velez, Nicolas Babault, Prashasti Kumar +3 more

Inactive and active state structures template selective tools for the human 5-HT5A receptor

Nature Structural & Molecular Biology(2022)10.1038/s41594-022-00796-6

N/A

0DataRank · unranked

29 citations

He Chen, Chengwei Zhang, Yang Ying, Petr Popov, Jing Liu +10 more

Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia

Cell Death and Disease(2022)10.1038/s41419-022-05002-5

N/A

0DataRank · unranked

13 citations

Samuel Kitara, Elisa Cerretani, Matteo Marchesini, Chiara Rompietti, Luca Pagliaro +24 more

Acetylation Targeting Chimera Enables Acetylation of the Tumor Suppressor p53

Journal of the American Chemical Society(2023)10.1021/jacs.3c04640

N/A

0DataRank · unranked

55 citations

Ning Sun, Xiaoping Hu, Tiphaine Martin, Jingjie Yi, Yue Zhong +6 more

Novel brain-penetrant inhibitor of G9a methylase blocks Alzheimer’s disease proteopathology for precision medication

medRxiv(2023)10.1101/2023.10.25.23297491

N/A

0DataRank · unranked

6 citations

Ryan N. Sheehy, Yan Xiong, Adil Muneer, John A. Wrobel, Kwang‐Su Park +13 more

Novel brain-penetrant inhibitor of G9a methylase blocks Alzheimer’s disease proteopathology for precision medication

Research Square(2023)10.21203/rs.3.rs-2743792/v1

N/A

0DataRank · unranked

1 citations

Ling Xie, Ryan N. Sheehy, Yan Xiong, Adil Muneer, John A. Wrobel +13 more