Saffie Mohran

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 13 papers. Top paper: “Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle”.

Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle

Circulation Research(2023)10.1161/circresaha.123.322629

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0DataRank · unranked

48 citations

Saffie Mohran, Kyrah L. Turner, Weikang Ma, Amy Martinson, Galina Flint +16 more

The biochemically defined super relaxed state of myosin—A paradox

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105565

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42 citations

Kristina B. Kooiker, Max Mahoney-Schaefer, Christian Mandrycky, Kerry Y. Kao, An-Yue Tu +5 more

Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.31.526380

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5 citations

Saffie Mohran, Kyrah L. Turner, Weikang Ma, Galina Flint, Lin Qi +16 more

Multi-scale models reveal hypertrophic cardiomyopathy MYH7 G256E mutation drives hypercontractility and elevated mitochondrial respiration

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.08.544276

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2 citations

Alison Schroer Vander Roest, Cheavar A. Blair, Kerry Y. Kao, Samantha Bremner, Matthew C. Childers +19 more

Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2318413121

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14 citations

Alison S. Vander Roest, Cheavar A. Blair, Kerry Y. Kao, Samantha Bremner, Matthew C. Childers +19 more

MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy

Journal of Molecular and Cellular Cardiology(2024)10.1016/j.yjmcc.2024.04.010

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14 citations

Saffie Mohran, Logan R.J. Bailey, Timothy S. McMillen, Kristina B. Kooiker, Neil B. Wood +8 more

Calcium has a direct effect on thick filament activation in porcine myocardium

The Journal of General Physiology(2024)10.1085/jgp.202413545

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9 citations

Timothy S. McMillen, Christian Mandrycky, An-Yue Tu, Kristina B. Kooiker, Wenjing Qian +7 more

The structural and functional effects of myosin regulatory light chain phosphorylation are amplified by increases in sarcomere length and [Ca2+]

The Journal of Physiology(2024)10.1113/jp286802

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5 citations

Blake J. Vander Top, Kristina B. Kooiker, Saffie Mohran, Christian Mandrycky, Timothy S. McMillen +5 more

Mechanisms of a novel regulatory light chain–dependent cardiac myosin inhibitor

The Journal of General Physiology(2024)10.1085/jgp.202313503

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3 citations

Qing-Fen Gan, Ming Yu, Na Sa, Saffie Mohran, Yuanhua Cheng +11 more

MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient-induced stem cell-derived cardiomyocyte model of hypertrophic cardiomyopathy

Biophysical Journal(2024)10.1016/j.bpj.2023.11.1955

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0DataRank · unranked

0 citations

Saffie Mohran, Logan R.J. Bailey, Timothy S. McMillen, Kristina B. Kooiker, Neil B. Wood +8 more

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model

Journal of Molecular and Cellular Cardiology(2025)10.1016/j.yjmcc.2025.10.008

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2 citations

Saffie Mohran, Matthew C. Childers, Timothy S. McMillen, Ateeqa Naim, Matvey Pilagov +14 more

Myosin modulator Aficamten inhibits force in cardiac muscle by altering myosin’s biochemical activity without changing thick filament structure

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.14.654110

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3 citations

Kristina B. Kooiker, Ateeqa Naim, Matvey Pilagov, Anthony Asencio, Kyrah L. Turner +13 more

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.27.672708

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0DataRank · unranked

3 citations

Saffie Mohran, Matthew C. Childers, Timothy S. McMillen, Ateeqa Naim, Matvey Pilagov +14 more