Kristen Brennand

Also affiliated with Université de Bretagne Occidentale, Yale University, Breakthrough, Yale New Haven Health System, Brennan & Company (Ireland), Icahn School of Medicine at Mount Sinai

Biochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

15.4Author DataRank

Indexed papers

9in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 9 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Scientific Data(2020)10.1038/s41597-020-00642-8

Top 3%

6.5DataRank

Top 3%331 citations

Thanneer M. Perumal, Minerva M. Carrasquillo, Mariet Allen, Joseph S. Reddy, Gabriel E. Hoffman +95 more

Papers

Driven by 59 papers — median percentile 82. Top paper: “Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions”.

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Scientific Data(2020)10.1038/s41597-020-00642-8

Top 3%

6.5DataRank

Top 3%331 citations

Thanneer M. Perumal, Minerva M. Carrasquillo, Mariet Allen, Joseph S. Reddy, Gabriel E. Hoffman +95 more

Multi-omic profiling of the developing human cerebral cortex at the single-cell level

Science Advances(2023)10.1126/sciadv.adg3754

Top 10%

2.0DataRank

Top 10%115 citations

Jaroslav Bendl, Samir Rahman, James M. Vicari, Claire Coleman, Tereza Clarence +9 more

Single-cell genomics and regulatory networks for 388 human brains

Science(2024)10.1126/science.adi5199

Top 12%

1.7DataRank

Top 12%155 citations

Jason Liu, Declan Clarke, Matthew Jensen, Jonathan Warrell, Chirag Gupta +91 more

Functional annotation of rare structural variation in the human brain

Nature Communications(2020)10.1038/s41467-020-16736-1

N/A

1.7DataRank · unranked

54 citations

Xuefang Zhao, Mary Lauren Benton, Thanneer M. Perumal, Ryan L. Collins, Gabriel E. Hoffman +65 more

Single-cell multi-cohort dissection of the schizophrenia transcriptome

Science(2024)10.1126/science.adg5136

N/A

1.3DataRank · unranked

125 citations

Shahin Mohammadi, José Dávila-Velderrain, Sivan Subburaju, Daniel Reed Tso, Makayla Hourihan +196 more

The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease

Nature Neuroscience(2022)10.1038/s41593-022-01166-7

Top 17%

1.2DataRank

Top 17%65 citations

Mads E. Hauberg, Kiran Girdhar, Eunju Im, James M. Vicari, Samir Rahman +17 more

A data-driven single-cell and spatial transcriptomic map of the human prefrontal cortex

Science(2024)10.1126/science.adh1938

Top 18%

1.2DataRank

Top 18%69 citations

Abby Spangler, Nicholas J. Eagles, Kelsey D. Montgomery, Sang Ho Kwon, Boyi Guo +90 more

Massively parallel characterization of regulatory elements in the developing human cortex

Science(2024)10.1126/science.adh0559

N/A

1.2DataRank · unranked

61 citations

Sean Whalen, Marilyn Steyert, Ryan Ziffra, Pawel F. Przytycki, Fumitaka Inoue +197 more

Population-level variation in enhancer expression identifies disease mechanisms in the human brain

Nature Genetics(2022)10.1038/s41588-022-01170-4

N/A

1.1DataRank · unranked

53 citations

Gabriel E. Hoffman, Pasha Apontes, Jaroslav Bendl, Samir Rahman, Michael B. Fernando +48 more

Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

Cell Genomics(2023)10.1016/j.xgen.2023.100356

N/A

1.0DataRank · unranked

43 citations

Maxwell A. Sherman, Giulio Genovese, Thomas G. Gilgenast, Tushar Kamath, S.J. Burris +95 more

Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets

Science Advances(2021)10.1126/sciadv.abb5398

N/A

0.873DataRank · unranked

337 citations

Minghui Wang, Sezen Vatansever, Lei Guo, Ming Chen, Qian Wang +19 more

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease

Neuron(2020)10.1016/j.neuron.2020.11.002

N/A

0.806DataRank · unranked

215 citations

Aiqun Li, Michiko Sekiya, Noam D. Beckmann, Xiuming Quan, Nadine Schrode +37 more

A psychiatric disease-related circular RNA controls synaptic gene expression and cognition

Molecular Psychiatry(2020)10.1038/s41380-020-0653-4

N/A

0.769DataRank · unranked

168 citations

Alexander Hafez, Stephen Amoah, Brian A. Rodriguez, Michela Dell’Orco, Evelyn Lozano +13 more

Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain

Science(2024)10.1126/science.adh0829

Top 26%

0.765DataRank

Top 26%50 citations

Michael Margolis, Rujia Dai, Pan Zhang, Pawel F. Przytycki, Daniel Vo +95 more

Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome

Nucleic Acids Research(2023)10.1093/nar/gkad798

Top 27%

0.756DataRank

Top 27%28 citations

Pengfei Dong, Pasha Apontes, Michael B. Fernando, Roman Kosoy, Kayla G. Townsley +10 more

Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders

Science Translational Medicine(2024)10.1126/scitranslmed.adh9974

Top 27%

0.733DataRank

Top 27%22 citations

Cuihua Xia, Yi Jiang, Yu Chen, Jiaqi Zhou, Rujia Dai +95 more

Stem Cell Models for Context-Specific Modeling in Psychiatric Disorders

Biological Psychiatry(2022)10.1016/j.biopsych.2022.09.033

N/A

0.707DataRank · unranked

12 citations

Laura M. Huckins, Kristen Brennand, Carina Seah

The functional and evolutionary impacts of human-specific deletions in conserved elements

Science(2023)10.1126/science.abn2253

N/A

0.657DataRank · unranked

79 citations

Ava Mackay-Smith, Kousuke Mouri, Meilín Fernández García, Michael X. Dong, Jared F. Akers +88 more

Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection

Stem Cell Reports(2021)10.1016/j.stemcr.2021.02.010

N/A

0.606DataRank · unranked

56 citations

Daisy A. Hoagland, Carina Seah, Bibi Kassim, Callan O’Shea, Aleta Murphy +19 more

Prenatal Δ9-Tetrahydrocannabinol Exposure in Males Leads to Motivational Disturbances Related to Striatal Epigenetic Dysregulation

Biological Psychiatry(2021)10.1016/j.biopsych.2021.09.017

N/A

0.606DataRank · unranked

56 citations

Anissa Bara, Claudia A. Vargas, Amy L. Frick, Eddie Loh, Joseph A. Landry +10 more

Multi-omic profiling of the developing human cerebral cortex at the single cell level

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.14.512250

Top 34%

0.573DataRank

Top 34%10 citations

Jaroslav Bendl, Samir Rahman, James M. Vicari, Claire Coleman, Tereza Clarence +9 more

Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission

Molecular Psychiatry(2024)10.1038/s41380-024-02561-1

N/A

0.566DataRank · unranked

21 citations

Lei Zhang, Meiyan Wang, Rebecca A. Wright, Idan Rosh, Yara Hussein +24 more

Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk

Molecular Psychiatry(2021)10.1038/s41380-021-01273-0

N/A

0.510DataRank · unranked

29 citations

Callan O’Shea, Kayla G. Townsley, Iya Prytkova, Kristina Dobrindt, Rahat Elahi +10 more

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome

Nature Communications(2022)10.1038/s41467-022-34200-0

N/A

0.489DataRank · unranked

25 citations

Wendy Wenderski, Ashley E. Lepack, Andrew L. Eagle, Tomas Fanutza, Ryan M. Bastle +22 more

A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility

npj Genomic Medicine(2022)10.1038/s41525-022-00324-x

N/A

0.442DataRank · unranked

18 citations

James M. Vicari, Sanan Venkatesh, Gabriel E. Hoffman, Kristina Dobrindt, Wen Zhang +27 more

Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons

STAR Protocols(2021)10.1016/j.xpro.2021.100580

N/A

0.434DataRank · unranked

17 citations

Samuel A. Cartwright, Alex W. Yu, Seok‐Man Ho, Nadine Schrode, P. J. Michael Deans +6 more

Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics

Molecular and Cellular Neuroscience(2020)10.1016/j.mcn.2020.103532

N/A

0.416DataRank · unranked

15 citations

Seok‐Man Ho, Nadine Schrode, Kristen Brennand, Marliette R. Matos

IL10RB as a key regulator of COVID-19 host susceptibility and severity

medRxiv(2021)10.1101/2021.05.31.21254851

N/A

0.406DataRank · unranked

14 citations

Gabriel E. Hoffman, Sanan Venkatesh, Kyung Min Lee, Kristina Dobrindt, James M. Vicari +25 more

Common genetic variation impacts stress response in the brain

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.27.573459

N/A

0.396DataRank · unranked

13 citations

Rebecca Signer, Michael R. Deans, Heather N. Bader, Tom Rusielewicz, Emily M. Hicks +19 more

Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.13.491776

N/A

0.373DataRank · unranked

11 citations

Lei Zhang, Meiyan Wang, Rebecca A. Wright, Diogo Cordeiro, David Peles +13 more

From compartments to gene loops: Functions of the 3D genome in the human brain

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.12.464094

N/A

0.308DataRank · unranked

6 citations

Pengfei Dong, Pasha Apontes, Michael B. Fernando, Kayla G. Townsley, Kiran Girdhar +9 more

Population-level variation of enhancer expression identifies novel disease mechanisms in the human brain

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.14.443421

N/A

0.269DataRank · unranked

5 citations

Gabriel E. Hoffman, Pasha Apontes, Jaroslav Bendl, Samir Rahman, Michael B. Fernando +12 more

BMI Interacts with the Genome to Regulate Gene Expression Globally, with Emphasis in the Brain and Gut

medRxiv(2024)10.1101/2024.11.26.24317923

N/A

0.208DataRank · unranked

3 citations

Carina Seah, Hannah Young, Kayla G. Townsley, Agathe de Pins, Alanna C. Cote +8 more

Polygenicity at the pathway level for anorexia nervosa

medRxiv(2025)10.1101/2025.10.08.25337623

N/A

0.165DataRank · unranked

2 citations

Jessica Johnson, Chao-Yu Liu, Judit García‐González, Shing Wan Choi, Kristen Brennand +4 more

Mechanical stretch disrupts calcium dynamics and redistributes Piezo1 in human astrocytes

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.08.681038

N/A

0DataRank · unranked

0 citations

Akash Chakka, Xi Xiao, Meilín Fernández García, Alexandra Yufa, Angela Mitevska +5 more

ASCL1- and DLX2-induced GABAergic neurons from hiPSC-derived NPCs

Journal of Neuroscience Methods(2020)10.1016/j.jneumeth.2019.108548

N/A

0DataRank · unranked

51 citations

Hanwen Zhang, Samuel K. Powell, Michael B. Fernando, Siwei Zhang, Erin Flaherty +5 more

Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models

Cells(2020)10.3390/cells9061406

N/A

0DataRank · unranked

9 citations

Emily Hoelzli, Rawan Abdelaal, Catherine Braine, Miguel Cuevas, Madeline Halpern +14 more

Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia

Complex Psychiatry(2020)10.1159/000512716

N/A

0DataRank · unranked

34 citations

Hanwen Zhang, Debamitra Das, Sara Abdollahi, Tim Prorok, Sulagna Ghosh +11 more

Parsing the Functional Impact of Noncoding Genetic Variants in the Brain Epigenome

Biological Psychiatry(2020)10.1016/j.biopsych.2020.06.033

N/A

0DataRank · unranked

25 citations

Callan O’Shea, Kristen Brennand, Schahram Akbarian, Samuel K. Powell

If there is not one cure for schizophrenia, there may be many

Schizophrenia(2020)10.1038/s41537-020-0101-0

N/A

0DataRank · unranked

3 citations

Kristen Brennand, Carina Seah

Cell-type specific in vitro gene expression profiling of stem-cell derived neural models

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.30.064709

N/A

0DataRank · unranked

0 citations

Emily Hoelzli, Rawan Abdelaal, Catherine Braine, Miguel Cuevas, Madeline Halpern +14 more

Gene expression elucidates functional impact of polygenic risk for schizophrenia

UNC Libraries(2020)10.17615/k6wj-s665

N/A

0DataRank · unranked

0 citations

Edwin C. Oh, Eli A. Stahl, David A. Bennett, Nicholas Katsanis, Tymor Hamamsy +53 more

Fitness selection of hyperfusogenic measles virus F proteins associated with neuropathogenic phenotypes

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2026027118

N/A

0DataRank · unranked

30 citations

Takao Hashiguchi, Chuan-Tien Hung, Kristina Dobrindt, Kristen Brennand, Makoto Takeda +2 more

Applying stem cells and CRISPR engineering to uncover the etiology of schizophrenia

Current Opinion in Neurobiology(2021)10.1016/j.conb.2021.04.003

N/A

0DataRank · unranked

23 citations

Kristen Brennand, P. J. Michael Deans

Xenopus models suggest convergence of gene signatures on neurogenesis in autism

Neuron(2021)10.1016/j.neuron.2021.02.017

N/A

0DataRank · unranked

3 citations

Michael E. Talkowski, Kristen Brennand

From compartments to gene loops: Functions of the 3D genome in the human brain

Research Square(2021)10.21203/rs.3.rs-964634/v1

N/A

0DataRank · unranked

0 citations

Samir Rahman, Pengfei Dong, Pasha Apontes, Michael B. Fernando, Kayla G. Townsley +9 more

A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning

Cell Reports(2022)10.1016/j.celrep.2021.110282

N/A

0DataRank · unranked

55 citations

Amber Zimmerman, Grigorios Papageorgiou, Jayapriya Chandrasekaran, Stephen Amoah, Rixing Lin +22 more

Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia

Nature Communications(2022)10.1038/s41467-022-29922-0

N/A

0DataRank · unranked

37 citations

Shuangping Zheng, Nadine Schrode, Aaron Topol, Natarajan V. Bhanu, Ryan M. Bastle +12 more

Schizophrenia-associated somatic copy number variants from 12,834 cases reveal contribution to risk and recurrent, isoform-specific NRXN1 disruptions

medRxiv(2022)10.1101/2021.12.24.21268385

N/A

0DataRank · unranked

4 citations

Maxwell A. Sherman, Giulio Genovese, Thomas G. Gilgenast, Prashanth Rajarajan, Erin Flaherty +14 more

Convergent coexpression of autism associated genes suggests some novel risk genes may not be detectable in large-scale genetic studies

medRxiv(2022)10.1101/2022.02.28.22271620

N/A

0DataRank · unranked

0 citations

Mariana Moysés‐Oliveira, Celine E. de Esch, Riya Bhavsar, Xander Nuttle, Aiqun Li +14 more

Convergent coexpression of autism-associated genes suggests some novel risk genes may not be detectable in large-scale genetic studies

Cell Genomics(2023)10.1016/j.xgen.2023.100277

N/A

0DataRank · unranked

24 citations

Mariana Moysés‐Oliveira, Celine E.F. De Esch, Riya Bhavsar, Xander Nuttle, Aiqun Li +14 more

Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders

Biological Psychiatry(2023)10.1016/j.biopsych.2023.07.003

N/A

0DataRank · unranked

17 citations

Jaroslav Bendl, Brigham J. Hartley, John F. Fullard, Rawan Abdelaal, Seok‐Man Ho +7 more

Better together: Non-additive interactions between schizophrenia risk genes

Cell Genomics(2023)10.1016/j.xgen.2023.100403

N/A

0DataRank · unranked

0 citations

Kristen Brennand, P. J. Michael Deans

Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease

Nature Neuroscience(2024)10.1038/s41593-024-01664-w

N/A

0DataRank · unranked

37 citations

Minghui Wang, Haofei Ni, Jinglong Zhang, Aiqun Li, Bin Hu +15 more

Somatic mosaicism in schizophrenia brains reveals prenatal mutational processes

Science(2024)10.1126/science.adq1456

N/A

0DataRank · unranked

21 citations

Attila Jones, Vladimir B. Seplyarskiy, Thanh Thanh L. Nguyen, Chaggai Rosenbluh, Taejong Bae +18 more

Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia

UNC Libraries(2024)10.17615/w913-sr13

N/A

0DataRank · unranked

0 citations

Jianwei Wang, A Charney, Vahram Haroutunian, Nancy Francoeur, Gil S.E +60 more

Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer’s disease

Nature Aging(2025)10.1038/s43587-025-00823-3

N/A

0DataRank · unranked

23 citations

Jean Kanyo, Rashaun S. Wilson, Shveta Bathla, Pablo Leal Cardozo, Лей Тонг +17 more

Whole-exome sequencing study of opioid dependence offers novel insights into the contributions of exome variants

Translational Psychiatry(2025)10.1038/s41398-025-03578-y

N/A

0DataRank · unranked

2 citations

Yaira Z. Nuñez, José Jaime Martínez‐Magaña, Melody Rivera-Hernández, Zhongzheng Mao, Kristen Brennand +5 more

Genotype‐by‐sex interaction analyses for alcohol use disorder across biobanks

Alcohol Clinical and Experimental Research(2025)10.1111/acer.70173

N/A

0DataRank · unranked

1 citations

Lu Wang, Zhongzheng Mao, P. J. Michael Deans, Rachel L. Kember, Qingyu Chen +12 more

Kristen Brennand

Indexed papers

Top data-sharing exemplar

Papers