Brett L. Hurst

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 32 papers. Top paper: “Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2”.

Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2

Nature Medicine(2022)10.1038/s41591-022-01908-x

N/A

2.9DataRank · unranked

56 citations

Menashe Elazar, Edward A. Pham, Siqi Tian, Lily Ben‐Avi, Claire Bernardin-Souibgui +27 more

High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

PLoS ONE(2021)10.1371/journal.pone.0250019

N/A

1.6DataRank · unranked

49 citations

Mowei Zhou, Roger Shek, Jesse Wilson, Logan Tillery, Justin K. Craig +14 more

Enhancing influenza vaccine immunogenicity and efficacy through infection mimicry using silk microneedles

Vaccine(2021)10.1016/j.vaccine.2021.07.064

N/A

1.4DataRank · unranked

38 citations

Archana V. Boopathy, Brian M. Cieslewicz, Yichen Zhang, Nickolas W. Hartman, David P. Miller +6 more

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

Cell Research(2020)10.1038/s41422-020-0356-z

N/A

1.0DataRank · unranked

888 citations

M. Sacco, Brett L. Hurst, Julia A. Townsend, Yanmei Hu, Tommy Szeto +6 more

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M pro and cathepsin L

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.27.223727

N/A

0.866DataRank · unranked

18 citations

Chunlong Ma, Panagiotis Lagarias, Ang Gao, Julia A. Townsend, Xiangzhi Meng +12 more

Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2

Nature Communications(2023)10.1038/s41467-023-37254-w

N/A

0.686DataRank · unranked

96 citations

Suman Pokhrel, Audrey Labbé, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson +28 more

Human IVIG treatment in a neurological disease model for Enterovirus A71 infection in 28-day-old AG129 mice

Virology(2023)10.1016/j.virol.2023.02.002

N/A

0.201DataRank · unranked

2 citations

Brett L. Hurst, W. Joseph Evans, Arnaud J. Van Wettere, Scott Gibson, Donald F. Smee +2 more

Boceprevir, calpain inhibitors II and XII, and GC-376 have broad-spectrum antiviral activity against coronaviruses in cell culture

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.30.362335

N/A

0DataRank · unranked

15 citations

Chunlong Ma, Tommy Szeto, Brett L. Hurst, E. Bart Tarbet, Jun Wang +1 more

Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity

UNC Libraries(2020)10.17615/9z66-ta09

N/A

0DataRank · unranked

0 citations

Michael D. Swanson, Hans‐Joachim Gabius, Irwin Goldstein, Donald F. Smee, Dominique Schols +21 more

ProLung™-budesonide Inhibits SARS-CoV-2 Replication and Reduces Lung Inflammation

Archives of Pharmacology and Therapeutics(2021)10.33696/pharmacol.3.028

N/A

0DataRank · unranked

2 citations

Ram Pattisapu, Jogi V. Pattisapu, Girija G. Konduri, John Zwetchkenbaum, Bidhan Roy +5 more

High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.21.427657

N/A

0DataRank · unranked

15 citations

Mowei Zhou, Roger Shek, Jesse Wilson, Logan Tillery, Justin K. Craig +14 more

Strain dependent structural effects and in vivo efficacy of enterovirus-D68 inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.24.474126

N/A

0DataRank · unranked

0 citations

Jianing Fu, Barbara Sherry, E. Bart Tarbet, Brett L. Hurst, Olga Riabova +12 more

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

UNC Libraries(2021)10.17615/5h4x-0k36

N/A

0DataRank · unranked

0 citations

Ethan J. Fritch, Brett L. Hurst, Peter B. Madrid, Carolina Horta Andrade, Thomas R. Lane +20 more

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

Nature Communications(2022)10.1038/s41467-022-29413-2

N/A

0DataRank · unranked

96 citations

Sho Iketani, Arie Zask, Nisha Khanizeman, Eva Bednářová, F. Forouhar +27 more

Anti‐SARS‐CoV‐2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID‐19 therapy

Journal of Medical Virology(2022)10.1002/jmv.28157

N/A

0DataRank · unranked

22 citations

Mikołaj Słabicki, Sita Ramaswamy, J. J. Patten, Charles Zou, Chengcheng Meng +12 more

TEMPOL inhibits SARS-CoV-2 replication and development of lung disease in the Syrian hamster model

iScience(2022)10.1016/j.isci.2022.105074

N/A

0DataRank · unranked

19 citations

Sara Cherry, D. Schultz, Brett L. Hurst, W. Marston Linehan, Tracey A. Rouault +1 more

An intranasal nanoparticle STING agonist has broad protective immunity against respiratory viruses and variants

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.18.488695

N/A

0DataRank · unranked

5 citations

Arash Saeedi, Monish Kumar, Samiur Rahman Sefat, Melisa Martinez-Paniagua, Mohsen Fathi +9 more

Ending transmission of SARS-CoV-2: sterilizing immunity using an intranasal subunit vaccine

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.14.500068

N/A

0DataRank · unranked

2 citations

Arash Saeedi, Samiur Rahman Sefat, Monish Kumar, Melisa Martinez-Paniagua, Adrian Damian +9 more

Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2

Research Square(2022)10.21203/rs.3.rs-906621/v2

N/A

0DataRank · unranked

0 citations

Suman Pokhrel, Audrey Labbé, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson +28 more

An Advax-CpG adjuvanted recombinant H5 hemagglutinin vaccine protects mice against lethal influenza infection

Vaccine(2023)10.1016/j.vaccine.2023.08.009

N/A

0DataRank · unranked

14 citations

E. Bart Tarbet, Brett L. Hurst, Nikolai Petrovsky, Yoshikazu Honda‐Okubo

Efficacy of an isoxazole-3-carboxamide analog of pleconaril in mouse models of Enterovirus-D68 and Coxsackie B5

Antiviral Research(2023)10.1016/j.antiviral.2023.105654

N/A

0DataRank · unranked

9 citations

Jianing Fu, Barbara Sherry, E. Bart Tarbet, Brett L. Hurst, Olga Riabova +15 more

An Isomer of Galidesivir That Potently Inhibits Influenza Viruses and Members of the Bunyavirales Order

ACS Medicinal Chemistry Letters(2023)10.1021/acsmedchemlett.3c00048

N/A

0DataRank · unranked

8 citations

Rinu Shrestha, James M. Wood, Keith Clinch, Brett L. Hurst, Hong Wang +8 more

An Advax-CpG55.2 adjuvanted recombinant hemagglutinin vaccine provides immunity against H7N9 influenza in adult and neonatal mice

Vaccine(2023)10.1016/j.vaccine.2023.07.061

N/A

0DataRank · unranked

5 citations

Isaac G. Sakala, Greiciely O. André, E. Bart Tarbet, Brett L. Hurst, Nikolai Petrovsky +1 more

Meeting report: 36th International Conference on Antiviral Research in Lyon, France – March 13–17, 2023

Antiviral Research(2023)10.1016/j.antiviral.2023.105678

N/A

0DataRank · unranked

4 citations

Kara Carter, Leen Delang, David Durantel, Brian B. Gowen, Lara J. Herrero +11 more

An intranasal nanoparticle STING agonist protects against respiratory viruses in animal models

Nature Communications(2024)10.1038/s41467-024-50234-y

N/A

0DataRank · unranked

22 citations

Arash Saeedi, Monish Kumar, K M Samiur Rahman Sefat, Melisa Martinez-Paniagua, Hui Meng +13 more

Structure-Activity Relationship Studies Towards Analogues of Pleconaril as Novel Enterovirus-D68 Capsid-Targeting Antivirals

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.08.668114

N/A

0DataRank · unranked

0 citations

Ed Griffen, Jessica Stacey, Alpha A. Lee, Yuliia Filimonova, Anton Hlavin +22 more

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L

Science Advances(2020)10.1126/sciadv.abe0751

N/A

0DataRank · unranked

399 citations

Chunlong Ma, Panagiotis Lagarias, Ang Gao, Julia A. Townsend, Xiangzhi Meng +12 more

Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease

Science Immunology(2020)10.1126/sciimmunol.aba4902

N/A

0DataRank · unranked

54 citations

Jianing Fu, Nurgun Kose, Lauren E. Williamson, Robin Bombardi, Ian Setliff +10 more

Structure activity relationship of novel antiviral nucleosides against Enterovirus A71

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127599

N/A

0DataRank · unranked

6 citations

Kiran S. Toti, Brett L. Hurst, Justin G. Julander, Kenneth A. Jacobson, Dilip K. Tosh

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.20.051581

N/A

0DataRank · unranked

92 citations

M. Sacco, Brett L. Hurst, Julia A. Townsend, Yanmei Hu, Tommy Szeto +6 more

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.407361

N/A

0DataRank · unranked

21 citations

Ethan J. Fritch, Thomas R. Lane, Longping V. Tse, Boyd L. Yount, Carol Queiroz Sacramento +19 more

A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.23.347534

N/A

0DataRank · unranked

17 citations

Chien‐Te K. Tseng, Aleksandra Drelich, Pavla Fajtová, Balachandra Chenna, Demetrios H. Kostomiris +24 more