H. Shelton Earp

University of North Carolina at Chapel Hill

Immunology and MicrobiologyBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.869Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Inherited predisposition to breast cancer in the Carolina Breast Cancer Study

npj Breast Cancer(2021)10.1038/s41523-020-00214-4

Top 23%

0.869DataRank

Top 23%13 citations

Süleyman Gülsüner, Ming K. Lee, Melissa A. Troester, Andrew F. Olshan, H. Shelton Earp +3 more

Papers

Driven by 48 papers — median percentile 77. Top paper: “Inherited predisposition to breast cancer in the Carolina Breast Cancer Study”.

Inherited predisposition to breast cancer in the Carolina Breast Cancer Study

npj Breast Cancer(2021)10.1038/s41523-020-00214-4

Top 23%

0.869DataRank

Top 23%13 citations

Süleyman Gülsüner, Ming K. Lee, Melissa A. Troester, Andrew F. Olshan, H. Shelton Earp +3 more

Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk

JNCI Journal of the National Cancer Institute(2020)10.1093/jnci/djaa056

N/A

0.648DataRank · unranked

74 citations

Nasim Mavaddat, Parichoy Pal Choudhury, Amber N. Hurson, Sara Lindström, Sabine Behrens +95 more

MERTK activation drives osimertinib resistance in EGFR-mutant non–small cell lung cancer

Journal of Clinical Investigation(2022)10.1172/jci150517

N/A

0.581DataRank · unranked

47 citations

Justus M. Huelse, Dmitri Kireev, Zikang Tan, Luxiao Chen, Subir Goyal +10 more

FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036

npj Breast Cancer(2021)10.1038/s41523-021-00258-0

N/A

0.483DataRank · unranked

24 citations

Timothy J. Stuhlmiller, Gaurav Mehta, Samantha M. Bevill, Daniel R. Goulet, José F. Olivares-Quintero +25 more

Inhibiting efferocytosis reverses macrophage-mediated immunosuppression in the leukemia microenvironment

Frontiers in Immunology(2023)10.3389/fimmu.2023.1146721

N/A

0.483DataRank · unranked

24 citations

Kristen C. Allison, Lauren S. Page, Alexis J. Jenkins, Xiaodong Wang, H. Shelton Earp +5 more

Differences in 21-Gene and PAM50 Recurrence Scores in Younger and Black Women With Breast Cancer

JCO Precision Oncology(2024)10.1200/po.24.00137

N/A

0.241DataRank · unranked

4 citations

Sanah Vohra, Joannie M. Ivory, Alina M. Hamilton, Xiaohua Gao, Erin L. Kirk +7 more

Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway

UNC Libraries(2020)10.17615/wmhg-2f32

N/A

0.241DataRank · unranked

4 citations

H. Shelton Earp, Xiong Li, June Weon Lee, Lee M. Graves

Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains

UNC Libraries(2020)10.17615/vnt3-7a98

N/A

0.208DataRank · unranked

3 citations

Jon S. Zawistowski, Lisa A. Carey, Rachel A. Reuther, Kazuhiro Nakamura, Steven P. Angus +15 more

Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.04.614143

N/A

0.181DataRank · unranked

2 citations

Robert W. Sprung, Denis O. Okumu, José F. Olivares-Quintero, Chinmaya U. Joisa, Xin Chen +21 more

Regulation of a Calcium-dependent Tyrosine Kinase in Vascular Smooth Muscle Cells by Angiotensin II and Platelet-derived Growth Factor: DEPENDENCE ON CALCIUM AND THE ACTIN CYTOSKELETON

UNC Libraries(2021)10.17615/q13m-gb33

N/A

0.165DataRank · unranked

2 citations

Debra M. Hunter, Yaqin He, Lee M. Graves, Xiong Li, Brian Herman +4 more

Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer

UNC Libraries(2020)10.17615/ebx5-w380

N/A

0.104DataRank · unranked

1 citations

Deborah A. Granger, Jon S. Zawistowski, David B. Darr, Alicia A. Midland, Jerry Usary +22 more

Evidence that the epidermal growth factor receptor and non-tyrosine kinase hormone receptors stimulate phosphoinositide hydrolysis by independent pathways

UNC Libraries(2020)10.17615/n8e1-cf59

N/A

0DataRank · unranked

0 citations

RA Jeffs, H. Shelton Earp, SG Rhee, WR Huckle, JR Hepler +2 more

Mutation of Androgen Receptor N-Terminal Phosphorylation Site Tyr-267 Leads to Inhibition of Nuclear Translocation and DNA Binding

UNC Libraries(2020)10.17615/sywd-bj41

N/A

0DataRank · unranked

0 citations

Dinuka De Silva, Zhentao Zhang, Mehmet Karaca, Yuanbo Liu, H. Shelton Earp +2 more

MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis

UNC Libraries(2020)10.17615/rsrx-4q11

N/A

0DataRank · unranked

0 citations

Melissa Sandahl, Karen E. Strunk, Jamie C. Stanford, H. Shelton Earp, Debra M. Hunter +7 more

MERTK receptor tyrosine kinase is a therapeutic target in melanoma

UNC Libraries(2020)10.17615/7cf0-0a25

N/A

0DataRank · unranked

0 citations

John J. Tentler, H. Shelton Earp, Stephen V. Frye, Amanda Winges, Weihe Zhang +20 more

Epidemiology of basal-like breast cancer (Breast Cancer Research and Treatment DOI: 10.1007/s10549-007-9632-6)

UNC Libraries(2020)10.17615/2kpx-j447

N/A

0DataRank · unranked

0 citations

Susan Jackson, Chiu Kit Tse, Sarah J. Nyante, Charles M. Perou, Patricia G. Moorman +10 more

Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer

Nucleic Acids Research(2021)10.1093/nar/gkab252

N/A

0DataRank · unranked

53 citations

Yi‐Hsuan Tsai, Phillip M. Galbo, Weida Gong, Aaron J. Storey, Yuemei Xu +13 more

Inhibition of the Calcium-dependent Tyrosine Kinase (CADTK) Blocks Monocyte Spreading and Motility

UNC Libraries(2021)10.17615/b4ym-8t51

N/A

0DataRank · unranked

0 citations

Vita Golubovskaya, Timothy W. Harding, H. Shelton Earp, J. S. Haskill, Debra M. Hunter +3 more

Interactions between Two Cytoskeleton-associated Tyrosine Kinases: Calcium-dependent Tyrosine Kinase and Focal Adhesion Tyrosine Kinase

UNC Libraries(2021)10.17615/jd31-kn25

N/A

0DataRank · unranked

5 citations

Xiong Li, Lee M. Graves, Ruth Dy, H. Shelton Earp, William G. Cance

A Calcium-dependent Tyrosine Kinase Splice Variant in Human Monocytes: ACTIVATION BY A TWO-STAGE PROCESS INVOLVING ADHERENCE AND A SUBSEQUENT INTRACELLULAR SIGNAL

UNC Libraries(2021)10.17615/9g7f-pe23

N/A

0DataRank · unranked

4 citations

Xiong Li, J. S. Haskill, John S Morris, H. Shelton Earp, Deborah Hunter

Platelet-derived growth factor (PDGF) alpha receptor activation modulates the calcium mobilizing activity of the PDGF beta receptor in Balb/c3T3 fibroblasts.

UNC Libraries(2021)10.17615/fe9a-m083

N/A

0DataRank · unranked

1 citations

Gerald W. Gordon, H. Shelton Earp, Brian Herman, Pamela A Diliberto, Chun Li Yu

Dual Inhibition of Focal Adhesion Kinase and Epidermal Growth Factor Receptor Pathways Cooperatively Induces Death Receptor-mediated Apoptosis in Human Breast Cancer Cells

UNC Libraries(2021)10.17615/he71-f276

N/A

0DataRank · unranked

0 citations

William G. Cance, Li Xu, Lucia Beviglia, H. Shelton Earp, Rolf J. Craven +1 more

An Intracellular Calcium Signal Activates p70 but Not p90 Ribosomal S6 Kinase in Liver Epithelial Cells

UNC Libraries(2021)10.17615/np3t-af11

N/A

0DataRank · unranked

0 citations

John M. Lambert, Deborah Hunter, Lee M. Graves, H. Shelton Earp, Yaqin He +1 more

A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant, promoting oncogene activation and tumorous transformation

Nucleic Acids Research(2022)10.1093/nar/gkac861

N/A

0DataRank · unranked

41 citations

Kwang‐Su Park, Xufen Yu, Weida Gong, H. Shelton Earp, Gang Greg Wang +3 more

Discovery and characterization of a functional scFv for CCR2 inhibition via an extracellular loop

International Journal of Pharmaceutics(2022)10.1016/j.ijpharm.2022.122547

N/A

0DataRank · unranked

4 citations

Adam D. Brown, Michael B. Deci, Silvina Matysiak, H. Shelton Earp, Juliane Nguyen +1 more

A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant promoting oncogene activation and tumorous transformation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.04.502794

N/A

0DataRank · unranked

5 citations

Kwang‐Su Park, Xufen Yu, Weida Gong, H. Shelton Earp, Gang Greg Wang +3 more

MERTK Inhibition as a Targeted Novel Cancer Therapy

International Journal of Molecular Sciences(2024)10.3390/ijms25147660

N/A

0DataRank · unranked

13 citations

Alisha Holtzhausen, Aashis Thapa, Justus M. Huelse, Douglas K. Graham, H. Shelton Earp +1 more

Discovery of Novel Macrocyclic MERTK/AXL Dual Inhibitors

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00148

N/A

0DataRank · unranked

10 citations

Qiang Tian, Zhilong Chen, Hongchao Zheng, Michael A. Stashko, Dan Yan +7 more

MerTK Induces Dysfunctional Dendritic Cells by Metabolic Reprogramming

Cancer Immunology Research(2024)10.1158/2326-6066.cir-23-0666

N/A

0DataRank · unranked

6 citations

George M. Edwards, Debra M. Hunter, H. Shelton Earp, Alisha Holtzhausen, Eden Y. Zewdie

Outcomes of Hormone-Receptor Positive, HER2-Negative Breast Cancers by Race and Tumor Biological Features

UNC Libraries(2024)10.17615/vwvq-7g66

N/A

0DataRank · unranked

0 citations

E.L. Kirk, A.F. Olshan, M.A. Troester, H.B. Nichols, H.C. Benefield +9 more

MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression

UNC Libraries(2024)10.17615/2v44-5k13

N/A

0DataRank · unranked

0 citations

Yixuan Zhang, Yufei Jiang, Peng Liu, Nikolay V. Dokholyan, Chunhai Fan +13 more

The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia

UNC Libraries(2024)10.17615/dgnw-zr34

N/A

0DataRank · unranked

0 citations

Craig T. Jordan, Stephen V. Frye, Catherine C. Smith, Dmitri Kireev, Katherine A. Minson +12 more

MERTK Inhibition as a Targeted Novel Cancer Therapy

UNC Libraries(2024)10.17615/q9p8-mz87

N/A

0DataRank · unranked

0 citations

Alisha Holtzhausen, Douglas K. Graham, Aashis Thapa, H. Shelton Earp, K.M. Tanim +1 more

Discovery of Novel TYRO3/MERTK Dual Inhibitors

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00009

N/A

0DataRank · unranked

4 citations

Jichen Zhao, Daowei Huang, Michael A. Stashko, Dan Yan, Ransheng Ding +11 more

PTP Inhibition Improves the Macrophage Antitumor Immune Response and the Efficacy of Chemo- and Radiotherapy

Cancer Immunology Research(2025)10.1158/2326-6066.cir-24-0335

N/A

0DataRank · unranked

1 citations

Paran Goel, Oluwagbemiga A. Ojo, Katarina Moretto, Alisha Holtzhausen, Angel Humphryes +11 more

Exploiting structural variability in the kinase back-pocket to modulate polypharmacology of TAM inhibitors

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.117561

N/A

0DataRank · unranked

0 citations

Dehui� Zhang, Zhilong Chen, Andrew L. McIver, Justus M. Huelse, Jyoti Mahajan +12 more

Differences in 21-Gene and PAM50 Recurrence Scores in Younger and Black Women With Breast Cancer

UNC Libraries(2025)10.17615/4e5p-rq23

N/A

0DataRank · unranked

0 citations

Erin L. Kirk, Sanah Vohra, Eboneé N. Butler, Melissa A. Troester, Katherine A. Hoadley +7 more

Structure-guided design and engineering of a biparatopic antibody targeting CCR2 in triple negative breast cancer

Journal of Controlled Release(2025)10.1016/j.jconrel.2025.114340

N/A

0DataRank · unranked

0 citations

Y. Wang, Ameya Chaudhari, Omar M Budayr, Jessica Tetterton-Kellner, Alex Bastian +7 more

MerTK inhibition decreases immune suppressive glioblastoma-associated macrophages and neoangiogenesis in glioblastoma microenvironment

Neuro-Oncology Advances(2020)10.1093/noajnl/vdaa065

N/A

0DataRank · unranked

29 citations

Madison Butler, Meili Zhang, Wei Zhang, Hua Song, Lee Hwang +15 more

Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases

UNC Libraries(2020)10.17615/wdd2-nx53

N/A

0DataRank · unranked

4 citations

Z. Zhang, Mehmet Karaca, D. Gioeli, Yali Liu, H. Shelton Earp +1 more

The HER4 Cytoplasmic Domain, But Not Its C Terminus, Inhibits Mammary Cell Proliferation

UNC Libraries(2020)10.17615/p4da-5r46

N/A

0DataRank · unranked

3 citations

Carolyn I. Sartor, Laura S. Caskey, Rebecca S. Muraoka-Cook, H. Shelton Earp, Debra M. Hunter +4 more

UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia In Vitro and In Vivo

UNC Libraries(2020)10.17615/4pj9-cy35

N/A

0DataRank · unranked

3 citations

Sandra Christoph, Dmitri Kireev, Emily A. Hull-Ryde, Chao Yang, Deborah DeRyckere +16 more

YY1 cistrome analysis uncovers an essential requirement of the YY1:BRD4-PFKP regulatory axis for promoting tumorigenesis of castration-resistant prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.17.302596

N/A

0DataRank · unranked

0 citations

Yi‐Hsuan Tsai, Phillip M. Galbo, Weida Gong, Aaron J. Storey, Yuemei Xu +12 more

The Intracellular Domain of ErbB4 Induces Differentiation of Mammary Epithelial Cells

UNC Libraries(2020)10.17615/n64q-hx28

N/A

0DataRank · unranked

0 citations

Carty Husted, Melissa Sandahl, Klaus Elenius, Leah C. Miraglia, Debra M. Hunter +3 more

MerTK is required for apoptotic cell–induced T cell tolerance

UNC Libraries(2020)10.17615/r24d-qd46

N/A

0DataRank · unranked

0 citations

Yaming Wang, Roland Tisch, H. Shelton Earp, Glenn K. Matsushima, Yingsu Huang +6 more

MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme

UNC Libraries(2020)10.17615/smpz-dr69

N/A

0DataRank · unranked

0 citations

Manali Rupji, Deborah DeRyckere, Amy K. Keating, Douglas K. Graham, Jeanne Kowalski +8 more

Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution

UNC Libraries(2020)10.17615/rn4e-pn02

N/A

0DataRank · unranked

0 citations

Dana M. Brantley‐Sieders, David Vaught, Andrew E. Williams, Michelle D. Williams, Rebecca S. Cook +9 more

Ack1 Mediated AKT/PKB Tyrosine 176 Phosphorylation Regulates Its Activation

UNC Libraries(2020)10.17615/1nj4-9e17

N/A

0DataRank · unranked

0 citations

Saı̈d M. Sebti, Rebecca S. Muraoka-Cook, Robert W. Engelman, H. Shelton Earp, Bin Fang +11 more

H. Shelton Earp

Indexed papers

Top data-sharing exemplar

Papers