Costantino Pitzalis

Also affiliated with Barts Health NHS Trust, William Harvey Research Institute, IRCCS Humanitas Research Hospital

MedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.578Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network

Arthritis Research & Therapy(2024)10.1186/s13075-024-03275-z

Top 34%

0.578DataRank

Top 34%25 citations

Mimi Kim, Philip M. Carlucci, Katherine Preisinger, Brooke Cohen, Kristina Deonaraine +90 more

Papers

Driven by 29 papers — median percentile 66. Top paper: “Notch signalling drives synovial fibroblast identity and arthritis pathology”.

Notch signalling drives synovial fibroblast identity and arthritis pathology

Nature(2020)10.1038/s41586-020-2222-z

N/A

9.3DataRank · unranked

544 citations

Ilya Korsunsky, Jennifer L. Marshall, Anqi Gao, Gerald F. Watts, Triin Major +70 more

Role of lymphoid chemokines in the development of functional ectopic lymphoid structures in rheumatic autoimmune diseases

Immunology Letters(2012)10.1016/j.imlet.2012.04.013

N/A

3.9DataRank · unranked

90 citations

Michele Bombardieri, Antonio Manzo, Serena Bugatti, Mariagrazia Uguccioni, Costantino Pitzalis +1 more

Granzyme K activates the entire complement cascade

Nature(2025)10.1038/s41586-025-08713-9

N/A

1.5DataRank · unranked

118 citations

Erin Theisen, Fan Zhang, Aparna Nathan, Madison L. Fairfield, Karishma Vijay Rupani +89 more

Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium

Nature Communications(2024)10.1038/s41467-024-49186-0

N/A

1.1DataRank · unranked

56 citations

Aaron B. Wagner, Nida Meednu, Ruoqiao Huiyi Wang, Fan Zhang, Jabea Cyril Ekabe +84 more

Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis

Nature Communications(2024)10.1038/s41467-024-52586-x

N/A

1.1DataRank · unranked

18 citations

Tan‐Yun Cheng, Ilya Korsunsky, Gerald F. Watts, Shani T. Gal-Oz, William V. Trim +94 more

Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles

Nature Genetics(2024)10.1038/s41588-024-01682-1

N/A

0.972DataRank · unranked

52 citations

Kathryn Weinand, Shakson Isaac, Kushal K. Dey, Karthik A. Jagadeesh, Masahiro Kanai +86 more

Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis

Journal of Clinical Investigation(2025)10.1172/jci185217

N/A

0.717DataRank · unranked

31 citations

Joshua Keegan, Alec Griffith, Tusharkanti Ghosh, Alice Horisberger, Kaitlyn Howard +37 more

Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus

Nature(2024)10.1038/s41586-024-07627-2

N/A

0.672DataRank · unranked

87 citations

Vanessa Sue Wacleche, Ye Cao, Arundhati Pillai, John M. Sowerby, Brandon L. Hancock +95 more

Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis

Science Translational Medicine(2024)10.1126/scitranslmed.adk3506

N/A

0.635DataRank · unranked

68 citations

Nicholas Bartelo, Maryam Aslam, Elisabeth A. Murphy, Caryn Hale, Nathalie E. Blachère +69 more

Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis

Cellular and Molecular Immunology(2023)10.1038/s41423-023-01108-8

N/A

0.590DataRank · unranked

50 citations

Stephanie R. Zack, Wes Nijim, Adel C. Burgos, V. Patel, Brian Zanotti +9 more

Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network

Arthritis Research & Therapy(2024)10.1186/s13075-024-03275-z

Top 34%

0.578DataRank

Top 34%25 citations

Mimi Kim, Philip M. Carlucci, Katherine Preisinger, Brooke Cohen, Kristina Deonaraine +90 more

Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression

Cell Reports(2022)10.1016/j.celrep.2022.110766

N/A

0.578DataRank · unranked

46 citations

Javier Rangel‐Moreno, Fan Zhang, Katherine Escalera-Rivera, Elisa Corsiero, Edoardo Prediletto +10 more

Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution

Nature Genetics(2023)10.1038/s41588-023-01586-6

N/A

0.571DataRank · unranked

44 citations

Amber Shen, Saisriram Gurajala, Aparna Nathan, Laurie Rumker, Vitor R. C. Aguiar +95 more

The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis

Nature Communications(2024)10.1038/s41467-024-48620-7

N/A

0.553DataRank · unranked

39 citations

Saori Sakaue, Aparna Nathan, A. Helena Jonsson, Fan Zhang, Gerald F. Watts +82 more

Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.18.533282

N/A

0.542DataRank · unranked

12 citations

Aaron B. Wagner, Nida Meednu, Fan Zhang, A. Helena Jonsson, Kevin Wei +19 more

Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.25.481990

N/A

0.515DataRank · unranked

30 citations

A. Helena Jonsson, Aparna Nathan, Kevin Wei, Nghia Millard, Qian Xiao +80 more

Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features

The Journal of Immunology(2022)10.4049/jimmunol.2101170

N/A

0.494DataRank · unranked

26 citations

Kevin D. Deane, Elizabeth A. Bemis, C. Strickland, Jennifer Seifert, Kimberly R. Jordan +7 more

Another Notch in the Belt of Rheumatoid Arthritis

Arthritis & Rheumatology(2024)10.1002/art.42937

N/A

0.457DataRank · unranked

20 citations

Osama Alzoubi, Neha Satoeya, Kunwar P. Singh, Sania Deen, Wes Nijim +6 more

Isolation and Characterization of Mouse and Human Follicular Dendritic Cells

Methods in Molecular Biology(2017)10.1007/978-1-4939-7095-7_10

N/A

0.433DataRank · unranked

13 citations

Riham El Sayed, Costantino Pitzalis, Mohey Eldin M. El Shikh

Notch ligands are biomarkers of anti-TNF response in RA patients

Angiogenesis(2023)10.1007/s10456-023-09897-2

N/A

0.391DataRank · unranked

7 citations

Anja Meyer, Brian Zanotti, Michael V. Volin, Sania Deen, Neha Satoeya +6 more

Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.03.547507

N/A

0.380DataRank · unranked

8 citations

Joshua Keegan, Alec Griffith, Tusharkanti Ghosh, Alice Horisberger, Kaitlyn Howard +34 more

Machine Learning Reveals Synovial Fibroblast Genes Associated with Pain Affect Sensory Nerve Growth in Rheumatoid Arthritis

medRxiv(2023)10.1101/2023.08.17.23294232

N/A

0.360DataRank · unranked

10 citations

Nicholas Bartelo, Maryam Aslam, Caryn Hale, Nathalie E. Blachère, Salina Parveen +19 more

Extrarenal symptoms associate with worse quality of life in patients enrolled in the AMP RA/SLE Lupus Nephritis Network

Lara D. Veeken(2024)10.1093/rheumatology/keae189

N/A

0.312DataRank · unranked

7 citations

Katherine Preisinger, Kristina Deonaraine, Devyn Zaminski, Maria Dall’Era, Heather T. Gold +88 more

Single cell analysis of RA synovial B cells reveals a dynamic spectrum of ectopic lymphoid B cell activation and hypermutation characterized by NR4A nuclear receptor expression

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.14.443150

N/A

0.144DataRank · unranked

1 citations

Javier Rangel‐Moreno, Fan Zhang, Katherine Escalera-Rivera, Elisa Corsiero, Edoardo Prediletto +11 more

Rituximab versus tocilizumab and B-cell status in TNF-alpha inadequate-responder rheumatoid arthritis patients: the R4-RA RCT

Efficacy and Mechanism Evaluation(2022)10.3310/gopl1729

N/A

0.104DataRank · unranked

1 citations

Patrick Durez, Maya H Buch, Myles Lewis, Stefano Bombardieri, Christopher R. John +14 more

Analysis of human factor H-related gene and protein expressed in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation

Scientific Reports(2025)10.1038/s41598-025-03589-1

N/A

0DataRank · unranked

5 citations

Larry W. Moreland, Kevin D. Deane, Dmitri Simberg, Robert I Scheinman, Rachel M. Frank +54 more

Pathotype-Specific Expression of Granzyme-Perforin Pathway Genes and Their Association With Clinical Disease Activity in Early Rheumatoid Arthritis and in a Randomized Clinical Trial

Immune Network(2025)10.4110/in.2025.25.e25

N/A

0DataRank · unranked

2 citations

Larry W. Moreland, Luigi Nibali, Michael A. Curtis, Kevin Deane, C. Strickland +11 more

Pathotype-Specific Expression of Granzyme-Perforin Pathway Genes and their Association with Clinical Disease Activity in Early Rheumatoid Arthritis and in a Randomized Clinical Trial 2923

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.780

N/A

0DataRank · unranked

0 citations

Larry W. Moreland, Luigi Nibali, Mike Curtis, Kevin Deane, C. Strickland +10 more

Syntenin-1-mediated arthritogenicity is advanced by reprogramming RA metabolic macrophages and Th1 cells

Annals of the Rheumatic Diseases(2023)10.1136/ard-2022-223284

N/A

0DataRank · unranked

26 citations

Ryan E Sienes, Wes Nijim, Brian Zanotti, Sadiq Umar, Michael V. Volin +11 more

Costantino Pitzalis

Indexed papers

Top data-sharing exemplar

Papers