Anna‐Leigh Brown

Also affiliated with The London College, University College London

MedicineBiochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 21 papers. Top paper: “Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer”.

Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer

Cell Reports Medicine(2020)10.1016/j.xcrm.2020.100007

N/A

5.6DataRank · unranked

182 citations

Anna‐Leigh Brown, Jun S. Wei, Svetlana Pack, Christopher Trindade, Chul Kim +26 more

Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

Journal of Clinical Investigation(2020)10.1172/jci139741

N/A

4.5DataRank · unranked

259 citations

Jack Humphrey, Sarah Pickles, Anna‐Leigh Brown, Sarah E. Hill, Jennifer M. Kachergus +47 more

Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD

Science Translational Medicine(2024)10.1126/scitranslmed.adg7162

N/A

0.769DataRank · unranked

168 citations

Yue Qi, Anna‐Leigh Brown, Oscar G. Wilkins, Colleen Bereda, Cédric Belair +46 more

Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer

Nature Communications(2021)10.1038/s41467-021-24164-y

N/A

0.769DataRank · unranked

167 citations

Moises J. Velez, Alberto Chiappori, Yoo Sun Kim, Jun S. Wei, Sivasish Sindiri +13 more

The era of cryptic exons: implications for ALS-FTD

Molecular Neurodegeneration(2023)10.1186/s13024-023-00608-5

N/A

0.757DataRank · unranked

154 citations

Anna‐Leigh Brown, Michael E. Ward, Pietro Fratta, Puja R. Mehta

HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing

Acta Neuropathologica(2021)10.1007/s00401-021-02340-0

N/A

0.598DataRank · unranked

53 citations

Ariana Gatt, Jack Humphrey, Sara Cappelli, Dipanjan Bhattacharya, S Foti +9 more

TDP-43 loss induces cryptic polyadenylation in ALS/FTD

Nature Neuroscience(2025)10.1038/s41593-025-02050-w

N/A

0.593DataRank · unranked

23 citations

Anna‐Leigh Brown, Max Z. Y. J. Chien, Dario Dattilo, Puja R. Mehta, Francesca Mattedi +94 more

Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.23.525149

N/A

0.550DataRank · unranked

38 citations

Yue Qi, Anna‐Leigh Brown, Oscar G. Wilkins, Colleen Bereda, Cédric Belair +41 more

Creation of de novo cryptic splicing for ALS and FTD precision medicine

Science(2024)10.1126/science.adk2539

N/A

0.538DataRank · unranked

35 citations

Max Z. Y. J. Chien, Josette J Wlaschin, Simone Barattucci, Peter Harley, Francesca Mattedi +19 more

Unexpected frequency of the pathogenic AR CAG repeat expansion in the general population

Brain(2023)10.1093/brain/awad050

N/A

0.505DataRank · unranked

28 citations

Kristina Ibáñez, Anna‐Leigh Brown, Prasanth Sivakumar, Alessandro Bombaci, Liana Santos +94 more

TDP-43 loss induces extensive cryptic polyadenylation in ALS/FTD

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.22.576625

N/A

0.489DataRank · unranked

25 citations

Anna‐Leigh Brown, Puja R. Mehta, Francesca Mattedi, Alla Mikheenko, Simone Barattucci +18 more

TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD

Nature Neuroscience(2025)10.1038/s41593-025-02096-w

N/A

0.442DataRank · unranked

18 citations

Kelly A. Marshall, Peter Harley, Jacob R. Mann, Francesco Alessandrini, Carlos G. Vanoye +32 more

Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization

Research Square(2021)10.21203/rs.3.rs-386600/v1

N/A

0.442DataRank · unranked

18 citations

Oscar G. Wilkins, Matthew J. Keuss, Sarah E. Hill, Matteo Zanovello, Weaverly Lee +18 more

Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.02.438170

N/A

0.425DataRank · unranked

16 citations

Oscar G. Wilkins, Matthew J. Keuss, Sarah E. Hill, Matteo Zanovello, Weaverly Colleen Lee +18 more

TDP-43 pathology induces CD8 + T cell activation through cryptic epitope recognition

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.22.660773

N/A

0.346DataRank · unranked

8 citations

Matteo Zanovello, Steven Lingyang Kong, Vidur J. Saigal, Anna‐Leigh Brown, Valentina Turchetti +34 more

Integrative multiomic analysis links TDP-43-driven splicing defects to cascading proteomic disruption of ALS/FTD pathways

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.29.679403

N/A

0DataRank · unranked

2 citations

Zhengde Liu, Keyana Blake, Yue Qi, Sasha Rollinson, Sahba Seddighi +13 more

Brain-derived neurotrophic factor amplifies neuron-intrinsic programs to enhance axonal regeneration in human motor neurons

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.06.565775

N/A

0DataRank · unranked

11 citations

Anna‐Leigh Brown, Kai Sun, Cathleen Hagemann, Bethany Geary, David Villarroel‐Campos +12 more

RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.24.563701

N/A

0DataRank · unranked

1 citations

Fergal M. Waldron, Rebecca S. Saleeb, Anna‐Leigh Brown, Olivia M. Rifai, Martina Gilodi +13 more

RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS

Acta Neuropathologica(2024)10.1007/s00401-024-02705-1

N/A

0DataRank · unranked

51 citations

Fergal M. Waldron, Rebecca S. Saleeb, Anna‐Leigh Brown, Olivia M. Rifai, Martina Gilodi +13 more

Correlates of Auditory Decision-Making in Prefrontal, Auditory, and Basal Lateral Amygdala Cortical Areas

Journal of Neuroscience(2020)10.1523/jneurosci.2217-20.2020

N/A

0DataRank · unranked

10 citations

Corrie R. Camalier, Anna‐Leigh Brown, Jessica T. Jacobs, Mortimer Mishkin, Bruno B. Averbeck +1 more

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Nature(2022)10.1038/s41586-022-04436-3

N/A

0DataRank · unranked

525 citations

Oscar G. Wilkins, Matthew J. Keuss, Sarah E. Hill, Matteo Zanovello, Weaverly Colleen Lee +90 more