Bryan D. Bryson

Also affiliated with Massachusetts General Hospital, Massachusetts Institute of Technology

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 49 papers. Top paper: “Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control”.

Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

Immunity(2022)10.1016/j.immuni.2022.04.004

N/A

4.8DataRank · unranked

294 citations

Travis K. Hughes, Constantine N. Tzouanas, Marc H. Wadsworth, Ang A. Tu, Todd M. Gierahn +38 more

Contrastive learning in protein language space predicts interactions between drugs and protein targets

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2220778120

N/A

4.5DataRank · unranked

191 citations

Samuel Sledzieski, Bryan D. Bryson, Lenore Cowen, Bonnie Berger, Rohit Singh

JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia

Med(2022)10.1016/j.medj.2021.12.003

N/A

1.1DataRank · unranked

24 citations

Joshua M. Peters, Travis Hughes, Caleb A. Lareau, Leif S. Ludwig, Lucas R. Massoth +12 more

TREM2 macrophages induced by human lipids drive inflammation in acne lesions

Science Immunology(2022)10.1126/sciimmunol.abo2787

N/A

0.757DataRank · unranked

154 citations

Feiyang Ma, Priscila R. Andrade, Rosane M. B. Teles, Bruno Jorge de Andrade Silva, Chanyue Hu +21 more

BHLHE40 Regulates Myeloid Cell Polarization through IL-10–Dependent and –Independent Mechanisms

The Journal of Immunology(2024)10.4049/jimmunol.2200819

N/A

0.278DataRank · unranked

4 citations

Yassin Mreyoud, Michael E. McNehlan, Asya Smirnov, Sthefany M. Chavez, Brian Hie +9 more

Multimodal profiling of lung granulomas reveals cellular correlates of tuberculosis control

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.24.352492

N/A

0.269DataRank · unranked

5 citations

Travis K. Hughes, Constantine N. Tzouanas, Marc H. Wadsworth, Ang Andy Tu, Todd M. Gierahn +37 more

Compressed phenotypic screens for complex multicellular models and high-content assays

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.23.525189

N/A

0.208DataRank · unranked

3 citations

Conner Kummerlowe, Nuo Liu, Walaa E. Kattan, Thomas W. Cheng, Jaime H. Cheah +11 more

Immunopeptidomics informs discovery and delivery of Mycobacterium tuberculosis MHC-II antigens for vaccine design

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.02.616386

N/A

0.165DataRank · unranked

2 citations

Paul Ogongo, Julia Huffaker, Mingyu Gan, Ryan O. Milligan, Sheikh Mahmud +9 more

IFN-γ- GranzymeB + Natural killer cells are induced by IV BCG vaccination and associated with protection against tuberculosis in rhesus macaques

Mucosal Immunology(2025)10.1016/j.mucimm.2025.10.011

N/A

0.104DataRank · unranked

1 citations

Emma Bishop, Allison N. Bucşan, Matt Sutton, Chelsea C. Lehman, Molly Robertson +8 more

An N-of-1 Trial of Itacitinib for a Patient with Aplastic Anemia Associated with a Gain-of-Function Variant in STAT1

Research Square(2021)10.21203/rs.3.rs-139401/v1

N/A

0.104DataRank · unranked

1 citations

Travis Hughes, Joshua M. Peters, Caleb A. Lareau, Leif S. Ludwig, Lucas R. Massoth +8 more

High-throughput screening for class I peptide MHC binding via yeast surface display

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.24.655874

N/A

0.104DataRank · unranked

1 citations

Kathryn C. Breuckman, Owen Leddy, Forest M. White, Bryan D. Bryson, Michael E. Birnbaum +1 more

Systems analysis reveals alternate metabolic states adopted by Mycobacterium tuberculosis across species

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.15.688116

N/A

0.104DataRank · unranked

1 citations

Rachel A. McGinn, Yisha Liang, Kendra A. Libby, Alison E. Ringel, Charles L. Evavold +2 more

Learning the language of viral evolution and escape

Science(2021)10.1126/science.abd7331

N/A

0DataRank · unranked

382 citations

Ellen D. Zhong, Bonnie Berger, Bryan D. Bryson, Brian Hie

MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2208900119

N/A

0DataRank · unranked

38 citations

Nicholas J. Rettko, Owen Leddy, Joshua M. Mesfin, Eric N. Brown, Shannon L. Winski +4 more

Artificial neural networks enable genome-scale simulations of intracellular signaling

Nature Communications(2022)10.1038/s41467-022-30684-y

N/A

0DataRank · unranked

45 citations

Joshua M. Peters, Nikolaos Meimetis, Bryan D. Bryson, Douglas A. Lauffenburger, Avlant Nilsson

CRISPR Interference Reveals That All- Trans -Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A

mBio(2022)10.1128/mbio.03683-21

N/A

0DataRank · unranked

36 citations

Michael A. DeJesus, Barbara Bosch, Michael R. Chase, Thibault Barbier, Amy K. Dickey +4 more

Fc-engineered antibodies leverage neutrophils to drive control of Mycobacterium tuberculosis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.01.490220

N/A

0DataRank · unranked

4 citations

Joshua M. Peters, Richard Lu, Patricia S. Grace, Jaimie Sixsmith, Aaron S. Wallace +11 more

Early cellular mechanism of type I interferon-driven susceptibility to tuberculosis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.06.511233

N/A

0DataRank · unranked

4 citations

Ophelia V. Lee, Stefan A. Fattinger, Charlotte A. Langner, Jaresley V. Guillen, Joshua M. Peters +8 more

MEK inhibition enhances presentation of targetable MHC-I tumor antigens in mutant melanomas

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.10.475285

N/A

0DataRank · unranked

2 citations

Nicholas J. Rettko, Owen Leddy, Joshua M. Mesfin, Eric N. Brown, Shannon L. Winski +4 more

Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.30.505882

N/A

0DataRank · unranked

0 citations

Forest M. White, Bryan D. Bryson, Owen Leddy

GM-CSF differentiation of human monocytes stabilizes macrophage state via oxidative signaling

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.29.318352

N/A

0DataRank · unranked

2 citations

Cal Gunnarsson, Gregory H. Babunovic, Armel Nibasumba, Ngomu Akeem Akilimali, Marc H. Wadsworth +8 more

Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

Cell(2023)10.1016/j.cell.2023.11.002

N/A

0DataRank · unranked

139 citations

Ophelia V. Lee, Stefan A. Fattinger, Charlotte A. Langner, Jaresley V. Guillen, Joshua M. Peters +8 more

Immunopeptidomics reveals determinants of Mycobacterium tuberculosis antigen presentation on MHC class I

eLife(2023)10.7554/elife.84070

N/A

0DataRank · unranked

55 citations

Forest M. White, Bryan D. Bryson, Owen Leddy

Selective Glycan Labeling of Mannose-Containing Glycolipids in Mycobacteria

Journal of the American Chemical Society(2023)10.1021/jacs.3c09495

N/A

0DataRank · unranked

12 citations

Victoria M. Marando, Stephanie R. Smelyansky, Daria E. Kim, Phillip J. Calabretta, Theodore C. Warner +3 more

Single-cell analysis reveals a weak macrophage subpopulation response to Mycobacterium tuberculosis infection

Cell Reports(2023)10.1016/j.celrep.2023.113418

N/A

0DataRank · unranked

9 citations

Bryan D. Bryson, Sydney L. Solomon

TLR2 is non-redundant in the population and subpopulation responses to Mycobacterium tuberculosis in macrophages and in vivo

mSystems(2023)10.1128/msystems.00052-23

N/A

0DataRank · unranked

8 citations

Sydney L. Solomon, Joshua M. Peters, Stephanie C. Pringle, Amelia E. Hinman, Julie Boucau +3 more

Maternal HIV infection drives altered placental Mtb-specific antibody transfer

Frontiers in Microbiology(2023)10.3389/fmicb.2023.1171990

N/A

0DataRank · unranked

3 citations

Wonyeong Jung, Maanasa Mendu, Tina Chen, Ryan P. McNamara, Sarah M. Fortune +7 more

Protective intravenous BCG vaccination induces enhanced immune signaling in the airways

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.16.549208

N/A

0DataRank · unranked

20 citations

Edward B. Irvine, Jacob M. Rosenberg, Marc H. Wadsworth, Travis K. Hughes, Matt Sutton +12 more

Learning with uncertainty for biological discovery and design

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.11.247072

N/A

0DataRank · unranked

5 citations

Bryan D. Bryson, Bonnie Berger, Brian Hie

Scanorama: integrating large and diverse single-cell transcriptomic datasets

Nature Protocols(2024)10.1038/s41596-024-00991-3

N/A

0DataRank · unranked

42 citations

Soochi Kim, Thomas A. Rando, Bryan D. Bryson, Bonnie Berger, Brian Hie

Fc-engineered antibodies promote neutrophil-dependent control of Mycobacterium tuberculosis

Nature Microbiology(2024)10.1038/s41564-024-01777-9

N/A

0DataRank · unranked

24 citations

Angel Nikolov, Mehak Zahoor Khan, Joshua M. Peters, Richard Lu, Jaimie Sixsmith +12 more

Validation and quantification of peptide antigens presented on MHCs using SureQuant

Nature Protocols(2024)10.1038/s41596-024-01076-x

N/A

0DataRank · unranked

11 citations

Yufei Cui, Ryuhjin Ahn, Lauren Stopfer, Elizabeth Choe, Duk‐Kyung Kim +5 more

Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface

Microbiology Spectrum(2024)10.1128/spectrum.02277-24

N/A

0DataRank · unranked

5 citations

Christine R. Zheng, Owen Leddy, Benjamin L. Allsup, Sydney L. Solomon, Bryan D. Bryson +1 more

Learning the language of viral evolution and escape

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.08.193946

N/A

0DataRank · unranked

7 citations

Ellen D. Zhong, Bonnie Berger, Bryan D. Bryson, Brian Hie

Systematic deconstruction of myeloid cell signaling in tuberculosis granulomas reveals IFN-γ, TGF-β, and time are associated with conserved myeloid diversity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.24.595747

N/A

0DataRank · unranked

5 citations

Hannah P. Gideon, Travis K. Hughes, Cal Gunnarson, Pauline Maiello, Douaa Mugahid +13 more

Proximity labeling defines the phagosome lumen proteome of murine and primary human macrophages

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.04.611277

N/A

0DataRank · unranked

2 citations

Supriya Gharpure, Bryan D. Bryson, Benjamin L. Allsup

Single Cell and Spatial Transcriptomics Defines the Cellular Architecture of the Antimicrobial Response Network in Human Leprosy Granulomas

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.01.406819

N/A

0DataRank · unranked

8 citations

Travis K. Hughes, Rosane M. B. Teles, Priscila R. Andrade, Bruno Jorge de Andrade Silva, Olesya Plazyo +14 more

Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.02.601718

N/A

0DataRank · unranked

0 citations

Christine R. Zheng, Owen Leddy, Benjamin L. Allsup, Sydney L. Solomon, Bryan D. Bryson +1 more

Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction

Immunity(2025)10.1016/j.immuni.2025.05.004

N/A

0DataRank · unranked

14 citations

Joshua M. Peters, Jaimie Sixsmith, Richard Lu, Edward B. Irvine, Corinne Luedeman +22 more

Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens

Science Translational Medicine(2025)10.1126/scitranslmed.adw9184

N/A

0DataRank · unranked

9 citations

Paul Ogongo, Julia Huffaker, Mingyu Gan, R. A. Milligan, Sheikh Mahmud +10 more

Dynamics of Th1/Th17 responses and antimicrobial pathways in leprosy skin lesions

Journal of Clinical Investigation(2025)10.1172/jci190736

N/A

0DataRank · unranked

6 citations

Feiyang Ma, Jing Lü, Jaime de Anda, Ernest Y. Lee, George W. Agak +13 more

Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery

The Journal of Experimental Medicine(2025)10.1084/jem.20250444

N/A

0DataRank · unranked

6 citations

Yuko Yuki, Mary Carrington, Bryan D. Bryson, Forest M. White, Owen Leddy

Leveraging Uncertainty in Machine Learning Accelerates Biological Discovery and Design

Cell Systems(2020)10.1016/j.cels.2020.09.007

N/A

0DataRank · unranked

162 citations

Bryan D. Bryson, Bonnie Berger, Brian Hie

High-throughput screening for class I peptide MHC binding via yeast surface display

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2514741122

N/A

0DataRank · unranked

1 citations

Kathryn C. Breuckman, Owen Leddy, Forest M. White, Bryan D. Bryson, Michael E. Birnbaum +1 more

Dissecting antimicrobial logic: species-specific strategies for intracellular pathogen defense

mSphere(2025)10.1128/msphere.00091-25

N/A

0DataRank · unranked

0 citations

Bryan D. Bryson

Control of antigen presentation on MHC-I by a bacterial secretion system

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.19.689332

N/A

0DataRank · unranked

0 citations

Rachel A. McGinn, Benjamin L. Allsup, Madison Leone, Penny Timms, Matías Gutiérrez-González +7 more

Artificial neural networks enable genome-scale simulations of intracellular signaling

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.24.461703

N/A

0DataRank · unranked

3 citations

Joshua M. Peters, Bryan D. Bryson, Douglas A. Lauffenburger, Avlant Nilsson

TREM2 + macrophages accumulate in alveoli of human pulmonary tuberculosis providing a permissive niche for bacterial growth

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.15.664002

N/A

0DataRank · unranked

0 citations

Chaouki Benabdessalem, Jonathan Perrie, Cenfu Wei, Julie West, Bruno Jorge de Andrade Silva +26 more

Leveraging Immunopeptidomics To Study and Combat Infectious Disease

mSystems(2021)10.1128/msystems.00310-21

N/A

0DataRank · unranked

22 citations

Forest M. White, Bryan D. Bryson, Owen Leddy