Caroline A. Lewis

University of Massachusetts Chan Medical School

Also affiliated with Whitehead Institute for Biomedical Research

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 32 papers. Top paper: “Cell-programmed nutrient partitioning in the tumour microenvironment”.

Cell-programmed nutrient partitioning in the tumour microenvironment

Nature(2021)10.1038/s41586-021-03442-1

N/A

8.5DataRank · unranked

1028 citations

Matthew Z. Madden, Melissa M. Wolf, Anna Chytil, Jackie E. Bader, Andrew R. Patterson +27 more

A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma

Nature Metabolism(2021)10.1038/s42255-021-00350-6

N/A

1.7DataRank · unranked

48 citations

Carlos Sebastián, Christina M. Ferrer, Caroline A. Lewis, Moshe Sade-Feldman, Thomas J. LaSalle +19 more

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia

Science Translational Medicine(2021)10.1126/scitranslmed.aaz4564

N/A

0.862DataRank · unranked

312 citations

Priyanka Narayan, Julia Maeve Bonner, Nora Kory, Sebastian Boland, Aleksandra A. Arczewska +14 more

Methionine synthase is essential for cancer cell proliferation in physiological folate environments

Nature Metabolism(2021)10.1038/s42255-021-00486-5

N/A

0.702DataRank · unranked

107 citations

Alicia M. Darnell, Montana F. Reilly, Tenzin Kunchok, Lena Joesch-Cohen, Daniel W. Rosenberg +6 more

S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress

eLife(2023)10.7554/elife.79511

N/A

0.614DataRank · unranked

16 citations

Sneha Gopalan, Thien-Kim Nguyen, Alexander Munden, Dominique S. Lui, Matthew J. Fanelli +6 more

Cancer tissue of origin constrains the growth and metabolism of metastases

Nature Metabolism(2024)10.1038/s42255-024-01105-9

N/A

0.533DataRank · unranked

34 citations

Yetiş Gültekin, Peter Winter, Sidney Y. Vermeulen, Konstantine Tchourine, Keene L. Abbott +22 more

Screening in serum-derived medium reveals differential response to compounds targeting metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.25.529972

N/A

0.498DataRank · unranked

8 citations

Ahmed Ali, Dominick Casalena, Brian T. Do, Raphaël Ferreira, Jaime H. Cheah +25 more

Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization

Cell Reports(2022)10.1016/j.celrep.2022.111187

N/A

0.442DataRank · unranked

18 citations

Sarah J. Mitchell, Katia S. Chadaideh, J. Humberto Treviño-Villarreal, Jonathan Jung, Krystle C. Kalafut +14 more

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

eLife(2024)10.7554/elife.95652

N/A

0.442DataRank · unranked

18 citations

Ahmed Ali, Bradley I. Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D. Landis +16 more

Distinct S-adenosylmethionine synthases link phosphatidylcholine to mitochondrial function and stress survival

PLoS Biology(2025)10.1371/journal.pbio.3003075

N/A

0.165DataRank · unranked

2 citations

Arjamand Mushtaq, Dominique S. Lui, Katherine M. Edwards, Daniel P Higgins, Kasturi Biswas +16 more

A Microphysiological Model of Progressive Human Hepatic Insulin Resistance

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.08.631261

N/A

0.165DataRank · unranked

2 citations

Jessica L. Ungerleider, Erin N. Tevonian, Pierre Sphabmixay, Priyatanu Roy, Caroline A. Lewis +4 more

Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine

Science(2022)10.1126/science.abi9547

N/A

0DataRank · unranked

74 citations

Anna M. Puszynska, Justin M. Roberts, Andrea Armani, Thao P. Nguyen, Jessica B. Spinelli +9 more

S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.30.486419

N/A

0DataRank · unranked

0 citations

Sneha Gopalan, Thien-Kim Nguyen, Alexander Munden, Paula Vo, Caroline A. Lewis +4 more

Screening in serum-derived medium reveals differential response to compounds targeting metabolism

Cell chemical biology(2023)10.1016/j.chembiol.2023.08.007

N/A

0DataRank · unranked

31 citations

Ahmed Ali, Dominick Casalena, Brian T. Do, Raphaël Ferreira, Jaime H. Cheah +29 more

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.24.573250

N/A

0DataRank · unranked

0 citations

Ahmed Ali, Bradley I. Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D. Landis +16 more

Faecalibacterium prausnitzii A2-165 metabolizes host- and media-derived chemicals and induces transcriptional changes in colonic epithelium in GuMI human gut microphysiological system

Microbiome Research Reports(2024)10.20517/mrr.2024.14

N/A

0DataRank · unranked

5 citations

Caroline A. Lewis, Charles Wright, Kirsten Schneider, John Kemmitt, David L. Trumper +5 more

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

eLife(2024)10.7554/elife.95652.1

N/A

0DataRank · unranked

0 citations

Ahmed Ali, Bradley I. Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D. Landis +16 more

Reviewer #1 (Public Review): Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

(2024)10.7554/elife.95652.2.sa2

N/A

0DataRank · unranked

0 citations

Ahmed Ali, Bradley I. Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D. Landis +16 more

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

eLife(2024)10.7554/elife.95652.3

N/A

0DataRank · unranked

0 citations

Ahmed Ali, Bradley I. Reinfeld, Amy Deik, Sonu Subudhi, Madelyn D. Landis +16 more

SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation

Nature Communications(2025)10.1038/s41467-025-56130-3

N/A

0DataRank · unranked

12 citations

Ju Shi, Sarah Chang, Jason Yang, Samuel Block, Charles H. Adelmann +12 more

Functional Specialization of S-Adenosylmethionine Synthases Links Phosphatidylcholine to Mitochondrial Function and Stress Survival

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.20.639242

N/A

0DataRank · unranked

0 citations

Dominique S. Lui, Daniel P Higgins, Matthew J. Fanelli, Thien-Kim Ngyuen, Katherine M. Edwards +12 more

UCP1 Mitigates Hepatic Steatosis and Fibrosis Independent of Cold Exposure

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.05.666925

N/A

0DataRank · unranked

0 citations

Johnny Le, Rui Li, Ekaterina Korobkina, Flaviane de Fátima Silva, Maria Gaughan +12 more

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.08.140558

N/A

0DataRank · unranked

37 citations

Zhaoqi Li, Dan Y. Gui, Lucas B. Sullivan, Maria Zagorulya, Brian T. Do +9 more

Dihydroxyacetone phosphate signals glucose availability to mTORC1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.21.161927

N/A

0DataRank · unranked

25 citations

Patrycja A. Krawczyk, Sonia M. Scaria, Andrew L. Cangelosi, Sze Ham Chan, Tenzin Kunchok +3 more

Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.16.951681

N/A

0DataRank · unranked

1 citations

Min-Sik Lee, Unmesh Jadhav, Insia Naqvi, Shariq Madha, Ashley Adler +14 more

MCART1 is required for mitochondrial NAD transport

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.28.267252

N/A

0DataRank · unranked

0 citations

Jelmi uit de Bos, Sanne van der Rijt, Nevena Jankovic, Miriam A. Güra, Nicholas L. Arp +7 more

High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

Cell Reports(2021)10.1016/j.celrep.2021.109212

N/A

0DataRank · unranked

203 citations

Amanda M. Hussey, Constantine N. Tzouanas, Shinya Imada, Yesenia Barrera Millan, Dorukhan Bahceci +8 more

Identifying Cell‐Type‐Specific Metabolic Signatures Using Transcriptome and Proteome Analyses

Current Protocols(2021)10.1002/cpz1.245

N/A

0DataRank · unranked

9 citations

Shahadat Rahman, Caroline A. Lewis, Alessandro Ori‬‬, Chia‐Wei Cheng, Nadja Gebert

Nucleotide imbalance decouples cell growth from cell proliferation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.06.471399

N/A

0DataRank · unranked

9 citations

Teemu P. Miettinen, Ryan Elbashir, Christopher S. Nabel, Scott R. Manalis, Caroline A. Lewis +2 more

Nucleotide imbalance decouples cell growth from cell proliferation

Nature Cell Biology(2022)10.1038/s41556-022-00965-1

N/A

0DataRank · unranked

220 citations

Teemu P. Miettinen, Ryan Elbashir, Christopher S. Nabel, Alicia M. Darnell, Brian T. Do +4 more

Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading

The Journal of Experimental Medicine(2022)10.1084/jem.20220654

N/A

0DataRank · unranked

143 citations

Caroline A. Lewis, Jason D. Ulrich, David M. Holtzman, Nimansha Jain

CLN3 is required for the clearance of glycerophosphodiesters from lysosomes

Nature(2022)10.1038/s41586-022-05221-y

N/A

0DataRank · unranked

140 citations

Wentao Dong, Uche N. Medoh, Andrew L. Cangelosi, Vimisha Dharamdasani, Sze Ham Chan +11 more