Kun‐Liang Guan

Also affiliated with University of California San Diego, Moores Cancer Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 48 papers. Top paper: “The multifaceted role of autophagy in cancer”.

The multifaceted role of autophagy in cancer

The EMBO Journal(2022)10.15252/embj.2021110031

N/A

0.816DataRank · unranked

229 citations

Kun‐Liang Guan, Ryan C. Russell

Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer

Nature Communications(2022)10.1038/s41467-022-28691-0

N/A

0.745DataRank · unranked

143 citations

Tracy Tang, Gary D. Probst, Andrei W. Konradi, Chunyu Jin, Fulong Li +4 more

Mitogenic and Oncogenic Stimulation of K433 Acetylation Promotes PKM2 Protein Kinase Activity and Nuclear Localization

UNC Libraries(2020)10.17615/v6y9-1m61

N/A

0.543DataRank · unranked

11 citations

Di Zhao, Yue Xiong, Yanping Xu, Wei Wang, Xin Zhou +7 more

IDH1 and IDH2 Mutations in Tumorigenesis: Mechanistic Insights and Clinical Perspectives

UNC Libraries(2020)10.17615/bhtg-gb11

N/A

0.520DataRank · unranked

31 citations

Dan Ye, Yue Xiong, Hui Yang, Kun‐Liang Guan

Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase

UNC Libraries(2020)10.17615/sas0-nb48

N/A

0.464DataRank · unranked

21 citations

Qun‐Ying Lei, Yan Lin, Lisha Zhou, Mengtao Xiao, Shiwen Wang +4 more

TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

UNC Libraries(2021)10.17615/7y38-s237

N/A

0.457DataRank · unranked

20 citations

Kun‐Liang Guan, Heng Zhang, Bin Zhao, Yue Xiong, Jun Yao +4 more

SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense

UNC Libraries(2020)10.17615/f666-qd95

N/A

0.434DataRank · unranked

17 citations

Dan Ye, Renqiang Sun, Xiufei Chen, Shiwen Wang, Kun‐Liang Guan +8 more

Regulation of intermediary metabolism by protein acetylation

UNC Libraries(2020)10.17615/253k-3j60

N/A

0.396DataRank · unranked

13 citations

Kun‐Liang Guan, Yue Xiong

Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth

UNC Libraries(2020)10.17615/6pwx-d930

N/A

0.396DataRank · unranked

13 citations

Ruiting Lin, Tao Ren, Kun‐Liang Guan, Yue Xiong, Qun‐Ying Lei +3 more

NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells

UNC Libraries(2020)10.17615/ja35-yv06

N/A

0.373DataRank · unranked

11 citations

Zhou‐Li Cheng, Di Zhao, Meng-Tian Li, Qun‐Ying Lei, Shaowu Zou +4 more

Acetylation Negatively Regulates Glycogen Phosphorylase by Recruiting Protein Phosphatase 1

UNC Libraries(2020)10.17615/a74k-x982

N/A

0.292DataRank · unranked

6 citations

Wei Xu, Shiwen Wang, Shimin Zhao, Dan Ye, Yue Xiong +3 more

L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration

UNC Libraries(2020)10.17615/b8ah-bt67

N/A

0.165DataRank · unranked

2 citations

Yue Xiong, Xiaohui Wu, Bowen Jiang, Pengyuan Yang, Dan Ye +11 more

Tales from the Cryptkeeper: New Roles for Lats1/2 in Wnt-driven Homeostasis

Cell stem cell(2020)10.1016/j.stem.2020.04.011

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0DataRank · unranked

3 citations

Kun‐Liang Guan, Vivian Fu

D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth

UNC Libraries(2020)10.17615/0ws3-zc65

N/A

0DataRank · unranked

2 citations

Yukun Xia, Wanglong Deng, Zhong Kai Gu, Shenghong Ma, Fei Zhen Wu +6 more

Critical roles of phosphoinositides and NF2 in Hippo pathway regulation

Genes & Development(2020)10.1101/gad.333435.119

N/A

0DataRank · unranked

72 citations

Zhipeng Meng, Steven W. Plouffe, Zhijie Lin, Mingjie Zhang, Kun‐Liang Guan +1 more

The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCF β-TrCP E3 Ligase

UNC Libraries(2020)10.17615/g3va-0n12

N/A

0DataRank · unranked

0 citations

Shimin Zhao, Kun‐Liang Guan, Wei Huang, Zheng Zha, Tingting Li +9 more

Alterations of metabolic genes and metabolites in cancer

UNC Libraries(2020)10.17615/ks4n-t870

N/A

0DataRank · unranked

0 citations

Eric K. Oermann, Jing Wu, Kun‐Liang Guan, Yue Xiong

Correction: Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1

UNC Libraries(2020)10.17615/n1ve-9q15

N/A

0DataRank · unranked

0 citations

Bowen Jiang, Yue Xiong, Kun‐Liang Guan, Tengfei Zhang, Yang Chen +10 more

Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration

UNC Libraries(2020)10.17615/79a7-4c31

N/A

0DataRank · unranked

0 citations

Yiping Sun, Yue Xiong, Ying Yu, Feng Xu, Meng-Tian Li +7 more

A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation

UNC Libraries(2020)10.17615/jh9f-q113

N/A

0DataRank · unranked

0 citations

Pradip Raychaudhuri, Matthew D. Smith, Zhengyu Zha, Qun‐Ying Lei, Kun‐Liang Guan +6 more

PP1 Cooperates with ASPP2 to Dephosphorylate and Activate TAZ

UNC Libraries(2020)10.17615/d6y8-xf85

N/A

0DataRank · unranked

0 citations

Qun‐Ying Lei, Yue Xiong, Xianbo Lv, Yanping Xu, Kun‐Liang Guan +4 more

Targeted polyubiquitylation of RASSF1C by the Mule and SCF β-TrCP ligases in response to DNA damage

UNC Libraries(2020)10.17615/dxp0-px98

N/A

0DataRank · unranked

0 citations

Kun‐Liang Guan, Tingting Li, Xin Zhou, Feng Xu, Esther Y. Hsiang +2 more

Kinase Suppressor of Ras Forms a Multiprotein Signaling Complex and Modulates MEK Localization

UNC Libraries(2020)10.17615/dsrn-2k87

N/A

0DataRank · unranked

0 citations

Scott Stewart, Min Han, Yanping Zhang, Meera V. Sundaram, Kun‐Liang Guan +1 more

The N-terminal Phosphodegron Targets TAZ/WWTR1 Protein for SCF β-TrCP -dependent Degradation in Response to Phosphatidylinositol 3-Kinase Inhibition

UNC Libraries(2020)10.17615/nkqp-we68

N/A

0DataRank · unranked

0 citations

Yue Xiong, Wei Huang, Ying Jiang, Kun‐Liang Guan, Chen‐Ying Liu +4 more

Hippo signalling maintains ER expression and ER+ breast cancer growth

Nature(2021)10.1038/s41586-020-03131-5

N/A

0DataRank · unranked

91 citations

ZhengMing Wu, Feng Yang, Jianmin Zhang, Randy L. Johnson, Michael G. Rosenfeld +2 more

The two sides of Hippo pathway in cancer

Seminars in Cancer Biology(2021)10.1016/j.semcancer.2021.07.006

N/A

0DataRank · unranked

91 citations

Kun‐Liang Guan, Fulong Li

Co‐occurrence of BAP1 and SF3B1 mutations in uveal melanoma induces cellular senescence

Molecular Oncology(2021)10.1002/1878-0261.13128

N/A

0DataRank · unranked

27 citations

Dan Zhou, Guiming Zhang, Zhonglu Ren, Xin Luo, Peng Liu +9 more

A Role for NF-κB Essential Modifier/IκB Kinase-γ (NEMO/IKKγ) Ubiquitination in the Activation of the IκB Kinase Complex by Tumor Necrosis Factor-α

UNC Libraries(2021)10.17615/768e-d440

N/A

0DataRank · unranked

0 citations

Kun‐Liang Guan, Yue Xiong, Cun Yu Wang, Eric Tang

Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides

Nature Chemical Biology(2022)10.1038/s41589-022-01061-z

N/A

0DataRank · unranked

66 citations

Vivian Fu, Guangbo Liu, Tracy Tang, Andrei W. Konradi, Xiao Peng +9 more

Rheb regulates nuclear mTORC1 activity independent of farnesylation

Cell chemical biology(2022)10.1016/j.chembiol.2022.02.006

N/A

0DataRank · unranked

30 citations

Xin Zhou, Kun‐Liang Guan, Jin Zhang, Yanghao Zhong

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

The EMBO Journal(2022)10.15252/embj.2022110698

N/A

0DataRank · unranked

26 citations

ZhengMing Wu, Yongqi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu +6 more

Acetyl-CoA, protein acetylation, and liver cancer

Molecular Cell(2022)10.1016/j.molcel.2022.10.015

N/A

0DataRank · unranked

21 citations

Kun‐Liang Guan, ZhengMing Wu

YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis

Nature Communications(2023)10.1038/s41467-023-41585-z

N/A

0DataRank · unranked

50 citations

Junhui Su, Fu-long Li, Tao Chen, Jaimie Mayner, Adam J. Engler +4 more

The Arf family GTPases: Regulation of vesicle biogenesis and beyond

BioEssays(2023)10.1002/bies.202200214

N/A

0DataRank · unranked

14 citations

Kun‐Liang Guan, Fulong Li

Functional annotation of the Hippo pathway somatic mutations in human cancers

Nature Communications(2024)10.1038/s41467-024-54480-y

N/A

0DataRank · unranked

14 citations

Zhen Huang, Congsheng Xu, Gayoung Seo, Jeongmin An, Bing Yang +15 more

Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis

Cell Metabolism(2020)10.1016/j.cmet.2020.03.010

N/A

0DataRank · unranked

204 citations

Bishuang Cai, Xiaoming Yang, Oluwatoni O. Sonubi, Ze Zheng, Rajasekhar Ramakrishnan +14 more

Nano-puerarin regulates tumor microenvironment and facilitates chemo- and immunotherapy in murine triple negative breast cancer model

UNC Libraries(2024)10.17615/qz3s-rc46

N/A

0DataRank · unranked

0 citations

Huan Xu, Kun‐Liang Guan, Jia Li, Lixin Li, Leaf Huang +5 more

Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress

UNC Libraries(2020)10.17615/0crd-8n84

N/A

0DataRank · unranked

164 citations

Yi‐Ping Wang, Yi Yang, Zhi Ling, Yi Sun, Leilei Chen +10 more

Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity

Cell stem cell(2020)10.1016/j.stem.2020.05.008

N/A

0DataRank · unranked

337 citations

Robert Blum, Davide Bernareggi, Eivind Heggernes Ask, ZhengMing Wu, Hanna Julie Hoel +6 more

Hippo Signaling in Embryogenesis and Development

Trends in Biochemical Sciences(2020)10.1016/j.tibs.2020.08.008

N/A

0DataRank · unranked

249 citations

Kun‐Liang Guan, ZhengMing Wu

Heat stress activates YAP/TAZ to induce the heat shock transcriptome

Nature Cell Biology(2020)10.1038/s41556-020-00602-9

N/A

0DataRank · unranked

105 citations

Zhipeng Meng, Toshiro Moroishi, Kimberly C. Lin, Guobo Shen, Fei Mo +6 more

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

UNC Libraries(2020)10.17615/sx1w-pr44

N/A

0DataRank · unranked

22 citations

Kun‐Liang Guan, Yaohui Chen, Shimin Zhao, Qun‐Ying Lei, Yue Xiong +2 more

Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents

UNC Libraries(2020)10.17615/z5m0-qp67

N/A

0DataRank · unranked

12 citations

Dan Ye, Katherine A. Hoadley, Charles M. Perou, Lei Zhang, J. Q. Wu +6 more

Mechanistic insights into the regulation of metabolic enzymes by acetylation

UNC Libraries(2020)10.17615/mgc1-7908

N/A

0DataRank · unranked

10 citations

Yue Xiong, Kun‐Liang Guan

EIF3H Orchestrates Hippo Pathway–Mediated Oncogenesis via Catalytic Control of YAP Stability

Cancer Research(2020)10.1158/0008-5472.can-19-3718

N/A

0DataRank · unranked

44 citations

Honghong Zhou, Luca Ponzoni, Aiping Luo, Rui Zhu, Mingjing He +6 more

A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling

Cell Reports(2020)10.1016/j.celrep.2020.108118

N/A

0DataRank · unranked

27 citations

Ruiling Xie, Kun‐Liang Guan, Mingjie Zhang, Zhijie Lin

Nutrient Sensing, Metabolism, and Cell Growth Control

UNC Libraries(2020)10.17615/31eg-8m53

N/A

0DataRank · unranked

10 citations

Yue Xiong, Hai‐Xin Yuan, Kun‐Liang Guan

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

UNC Libraries(2020)10.17615/nn6d-wk72

N/A

0DataRank · unranked

10 citations

Shinsuke Ito, Yue Xiong, Li Xia Liu, Ying Yang, Wei Xu +17 more