Joshua W. Knowles

ORCID: 0000-0003-1922-7240

Also affiliated with Stanford Medicine, Stanford University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

3.2Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry

Journal of the American Heart Association(2023)10.1161/jaha.122.029175

Top 14%

1.5DataRank

Top 14%51 citations

Paul C. Lee, Lisa C. Hudgins, P. Barton Duell, Zahid Ahmad, Seth J. Baum +28 more

Papers

Driven by 57 papers — median percentile 71. Top paper: “Phased Whole-Genome Genetic Risk in a Family Quartet Using a Major Allele Reference Sequence”.

Phased Whole-Genome Genetic Risk in a Family Quartet Using a Major Allele Reference Sequence

PLoS Genetics(2011)10.1371/journal.pgen.1002280

N/A

7.5DataRank · unranked

148 citations

Rong Chen, Sergio P. Cordero, Kelly E. Ormond, Colleen Caleshu, Konrad J. Karczewski +33 more

Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study

Frontiers in Cardiovascular Medicine(2017)10.3389/fcvm.2017.00053

N/A

2.8DataRank · unranked

56 citations

Shirin Zarafshar, Aleksandra Pavlovic, Benjamin A. Goldstein, Sandra Tsai, Jin Li +8 more

Randomized Trial of Personal Genomics for Preventive Cardiology

Circulation: Cardiovascular Genetics(2012)10.1161/circgenetics.112.962746

N/A

1.6DataRank · unranked

30 citations

Themistocles L. Assimes, Michaela Kiernan, Aleksandra Pavlovic, Benjamin A. Goldstein, Veronica Yank +7 more

Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry

Journal of the American Heart Association(2023)10.1161/jaha.122.029175

Top 14%

1.5DataRank

Top 14%51 citations

Paul C. Lee, Lisa C. Hudgins, P. Barton Duell, Zahid Ahmad, Seth J. Baum +28 more

Children with Heterozygous Familial Hypercholesterolemia in the United States: Data from the Cascade Screening for Awareness and Detection-FH Registry

The Journal of Pediatrics(2020)10.1016/j.jpeds.2020.09.042

Top 16%

1.3DataRank

Top 16%27 citations

Peter Shrader, MacRae F. Linton, Joshua W. Knowles, Lisa C. Hudgins, Irwin Benuck +11 more

Discovery and quality analysis of a comprehensive set of structural variants and short tandem repeats

Nature Communications(2020)10.1038/s41467-020-16481-5

N/A

1.2DataRank · unranked

38 citations

Erin N. Smith, Matteo D’Antonio, Marc Jan Bonder, William W. Greenwald, Agnieszka D’Antonio‐Chronowska +14 more

Clinical assessment incorporating a personal genome

The Lancet(2010)10.1016/s0140-6736(10)60452-7

N/A

0.978DataRank · unranked

676 citations

Atul Janardhan Butte, Matthew T. Wheeler, Rong Chen, Teri E. Klein, Frederick E. Dewey +28 more

A guide for the diagnosis of rare and undiagnosed disease: beyond the exome

Genome Medicine(2022)10.1186/s13073-022-01026-w

N/A

0.894DataRank · unranked

387 citations

Joshua W. Knowles, Euan A. Ashley, Shruti Marwaha

Genetics of Type 2 Diabetes: Opportunities for Precision Medicine

Journal of the American College of Cardiology(2021)10.1016/j.jacc.2021.03.346

N/A

0.829DataRank · unranked

21 citations

Anna L. Gloyn, Joshua W. Knowles, Daniel Seung Kim

Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications

Endocrinology(2020)10.1210/endocr/bqaa017

N/A

0.806DataRank · unranked

215 citations

Kitt Falk Petersen, Gerald I. Shulman, Joshua W. Knowles, Panjamaporn Sangwung

Properties of structural variants and short tandem repeats associated with gene expression and complex traits

Nature Communications(2020)10.1038/s41467-020-16482-4

N/A

0.741DataRank · unranked

139 citations

Matteo D’Antonio, Marc Jan Bonder, Craig Smail, Margaret K. R. Donovan, William W. Greenwald +15 more

Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis

Cell Metabolism(2021)10.1016/j.cmet.2021.07.010

N/A

0.738DataRank · unranked

136 citations

Meng Zhao, Laëtitia Voilquin, Yunshin Jung, Mari Aikio, Tanushi Sahai +15 more

Lac-Phe mediates the effects of metformin on food intake and body weight

Nature Metabolism(2024)10.1038/s42255-024-00999-9

N/A

0.655DataRank · unranked

78 citations

Veronica L. Li, Xuchao Lyu, Xudong Chen, Wei Wei, Fahim Abbasi +22 more

Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics

Nature Genetics(2021)10.1038/s41588-021-00800-7

N/A

0.650DataRank · unranked

75 citations

Craig Smail, Michael J. Gloudemans, Laure Frésard, David Jakubosky, Matteo D’Antonio +22 more

Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness

PLoS Computational Biology(2020)10.1371/journal.pcbi.1008491

N/A

0.546DataRank · unranked

20 citations

Marc Henrion, Kuixi Zhu, Noam D. Beckmann, Paige Cundiff, Sara Moein +9 more

Plasma proteomic signatures of a direct measure of insulin sensitivity in two population cohorts

Diabetologia(2023)10.1007/s00125-023-05946-z

N/A

0.536DataRank · unranked

13 citations

Laurel Stell, Stefan Gustafsson, Fahim Abbasi, Philip S. Tsao, Joshua W. Knowles +33 more

An integrated approach to identify environmental modulators of genetic risk factors for complex traits

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.08.014

N/A

0.524DataRank · unranked

32 citations

Ivan Carcamo‐Orive, Michael J. Gloudemans, Daniel Nachun, Matthew G. Durrant, Steven Gazal +7 more

A functional genomic framework to elucidate novel causal metabolic dysfunction–associated fatty liver disease genes

Hepatology(2024)10.1097/hep.0000000000001066

N/A

0.482DataRank · unranked

14 citations

Johanne Marie Justesen, Amanda Ranta, Disha Sharma, Ewa Bielczyk-Maczyńska, Jiehan Li +16 more

Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models

Scientific Data(2023)10.1038/s41597-023-02293-x

Top 43%

0.441DataRank

Top 43%10 citations

Christopher Jin, Stefan Gustafsson, Abhiram Rao, Martin Wabitsch, Chong Y. Park +4 more

One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy

Frontiers in Cardiovascular Medicine(2024)10.3389/fcvm.2024.1429230

N/A

0.425DataRank · unranked

16 citations

Emily L. Chu, Emily Keamy-Minor, Ishan Paranjpe, Wilson L. Tang, Jack W. O’Sullivan +23 more

Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD

Hepatology Communications(2022)10.1002/hep4.1932

N/A

0.406DataRank · unranked

14 citations

Sophia Figueroa Katz, Johanne Marie Justesen, Jack W. O’Sullivan, Peter Saliba‐Gustafsson, Themistocles L. Assimes +6 more

X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

Nature Communications(2024)10.1038/s41467-024-49764-2

N/A

0.406DataRank · unranked

14 citations

Joseph J. Munier, Carrie B. Wiese, Laurent Vergnes, Jenny C. Link, Fahim Abbasi +16 more

Trends of Lipid Concentrations, Awareness, Evaluation, and Treatment in Severe Dyslipidemia in US Adults

Mayo Clinic Proceedings(2024)10.1016/j.mayocp.2023.09.016

N/A

0.373DataRank · unranked

11 citations

Mokshad Gaonkar, Nirav Patel, Joshua W. Knowles, Pradeep Natarajan, Garima Arora +2 more

Generation of two heterozygous MYBPC3 mutation-carrying human iPSC lines, SCVIi001-A and SCVIi002-A, for modeling hypertrophic cardiomyopathy

Stem Cell Research(2021)10.1016/j.scr.2021.102279

N/A

0.345DataRank · unranked

9 citations

Sushma Shenoy, James W.S. Jahng, Yu Liu, Joshua W. Knowles, Yan Zhuge +2 more

Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants

Stem Cell Research(2022)10.1016/j.scr.2022.102774

N/A

0.330DataRank · unranked

8 citations

James W.S. Jahng, Carlos Vera, Sushma Shenoy, Joshua W. Knowles, Joseph C. Wu +1 more

Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes

medRxiv(2021)10.1101/2021.09.28.21264208

N/A

0.269DataRank · unranked

5 citations

Brunilda Balliu, Daniel Nachun, Matthew G. Durrant, Erik Ingelsson, Martin Wabitsch +5 more

Cross-sectional, interventional, and causal investigation of insulin sensitivity using plasma proteomics in diverse populations

Metabolism(2025)10.1016/j.metabol.2025.156263

N/A

0.241DataRank · unranked

4 citations

Neil Wary, Daniela Zanetti, Fahim Abbasi, Joshua W. Knowles, Daniel J. Panyard +8 more

Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity

WOS(2020)10.17615/5vbx-b108

N/A

0.241DataRank · unranked

4 citations

Inês Barroso, Andrea Benazzo, Denis Rybin, Felicity Payne, Niels Grarup +27 more

Impact of Virtual Interviewing on Cardiovascular Fellowship Applicant Diversity: Insights From 2 Academic Programs

Journal of the American Heart Association(2023)10.1161/jaha.123.030255

N/A

0.165DataRank · unranked

2 citations

Joshua W. Knowles, Doreen DeFaria Yeh, Tariku J. Beyene, Santosh E. Gummipundi, Paul A. Heidenreich +2 more

Genetics of cardiometabolic disease progression

medRxiv(2025)10.1101/2025.02.01.25321518

N/A

0.114DataRank · unranked

1 citations

Guhan Venkataraman, Yosuke Tanigawa, Ruilin Li, Trevor Hastie, Robert Tibshirani +3 more

Personalized Medicine and Cardiovascular Disease: From Genome to Bedside

Current Cardiovascular Risk Reports(2011)10.1007/s12170-011-0202-4

N/A

0.104DataRank · unranked

1 citations

Frederick E. Dewey, Juan Manuel Peralta, Joshua W. Knowles, Rong Chen, Atul Janardhan Butte +3 more

Loss of RREB1 reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.30.605923

N/A

0.104DataRank · unranked

1 citations

Nicole A. J. Krentz, Liz Bentley, Meng Zhao, Keanu Paphiti, Han Sun +21 more

An integrated approach to identify environmental modulators of genetic risk factors for complex traits

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.23.432608

N/A

0.104DataRank · unranked

1 citations

Ivan Carcamo‐Orive, Michael J. Gloudemans, Daniel Nachun, Matthew G. Durrant, Steven Gazal +7 more

Genome-wide Characterization of Shared and Distinct Genetic Components that Influence Blood Lipid Levels in Ethnically Diverse Human Populations

UNC Libraries(2020)10.17615/613z-hx36

N/A

0DataRank · unranked

0 citations

Qing Duan, Nicholas A. Johnson, Marc Coram, Lisa Warsinger Martin, Neil Risch +12 more

Health disparities in cardiometabolic risk among Black and Hispanic youth in the United States

American Journal of Preventive Cardiology(2021)10.1016/j.ajpc.2021.100175

N/A

0DataRank · unranked

35 citations

Fátima Rodríguez, Joshua W. Knowles, Sophia Figueroa Katz

Another Use for Polygenic Risk Scores

JACC Advances(2023)10.1016/j.jacadv.2023.100663

N/A

0DataRank · unranked

0 citations

Joshua W. Knowles, Brian T. Palmisano

Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/egvr-xj58

N/A

0DataRank · unranked

0 citations

Kit E. Purdy, Peter J. Mohler, Xun Qian, Paula M. Oliver, Michael F. Goy +4 more

Low salt intake down-regulates the guanylin signaling pathway in rat distal colon

UNC Libraries(2020)10.17615/32pw-xg11

N/A

0DataRank · unranked

3 citations

Subhash Prabhakar, Douglas B. Short, Z. Li, Michael F. Goy, Ashley Perkins +2 more

Association of insulin resistance, from mid-life to late-life, with aortic stiffness in late-life: the Atherosclerosis Risk in Communities Study

Cardiovascular Diabetology(2020)10.1186/s12933-020-0986-y

N/A

0DataRank · unranked

53 citations

Michelle L. Meyer, Hirofumi Tanaka, Elizabeth Selvin, James S. Pankow, Donglin Zeng +5 more

Corrigendum: Simple, standardized incorporation of genetic risk into non-genetic risk prediction tools for complex traits: coronary heart disease as an example

Frontiers in Genetics(2015)10.3389/fgene.2015.00231

N/A

0DataRank · unranked

0 citations

Joshua W. Knowles, Elias Salfati, John P. A. Ioannidis, Themistocles L. Assimes, Benjamin A. Goldstein

Hymecromone Promotes Longevity and Insulin Sensitivity in Mice

Cells(2024)10.3390/cells13201727

N/A

0DataRank · unranked

5 citations

Kathryn S. Czepiel, Gernot Kaber, Darko Stefanovski, Aviv Hargil, Nina Pennetzdorfer +14 more

Generation of two familial hypercholesterolemia patient-specific induced pluripotent stem cell lines harboring heterozygous mutations in the LDLR gene

Stem Cell Research(2024)10.1016/j.scr.2024.103463

N/A

0DataRank · unranked

1 citations

Juana Li, Lingyun Xu, Christopher D. Yan, Joshua W. Knowles, Joseph C. Wu +1 more

Cross-sectional, interventional, and causal investigation of insulin sensitivity using plasma proteomics in diverse populations

medRxiv(2024)10.1101/2024.11.09.24317011

N/A

0DataRank · unranked

2 citations

Neil Wary, Daniela Zanetti, Fahim Abbasi, Joshua W. Knowles, Daniel J. Panyard +8 more

Generation of two induced pluripotent stem cell lines from healthy patients of African American ancestry

Stem Cell Research(2024)10.1016/j.scr.2024.103322

N/A

0DataRank · unranked

0 citations

Ana Kojic, Christina Alamana, Gabriela Canel, Celine Lai, Joshua W. Knowles +2 more

Electronic health records-based algorithms to screen for U.S. Centers for Disease Control and Prevention tier 1 genetic diseases: a scoping review

Journal of the American Medical Informatics Association(2025)10.1093/jamia/ocaf140

N/A

0DataRank · unranked

5 citations

M Hernandez, Khanh N H Ngo, Anne Fladger, Charles A. Brunette, Sulaiman R Hamarneh +4 more

Label‐Free Detection of Lipid Accumulation in Cells Using Magnetic Levitation

Advanced Biology(2025)10.1002/adbi.202200142

N/A

0DataRank · unranked

1 citations

Laeya A. Najmi, Rakhi Gupta, Malavika Ramarao, Joshua W. Knowles, Chong Y. Park +2 more

Many Journeys Originating at the Same Source to Arrive at Solutions to the Common Problem of High Lipoprotein(a)

Circulation Genomic and Precision Medicine(2025)10.1161/circgen.125.005126

N/A

0DataRank · unranked

0 citations

Joshua W. Knowles, Jean Woody Luxama

Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.27.534456

Top 100%

0DataRank

Top 100%0 citations

Christopher Jin, Stefan Gustafsson, Abhiram Rao, Martin Wabitsch, Chong Y. Park +4 more

FastGxC: Fast and Powerful Context-Specific eQTL Mapping in Bulk and Single-Cell Data

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.17.448889

N/A

0DataRank · unranked

11 citations

Andrew Lu, Mike Thompson, Cuining Liu, M. Grace Gordon, Amanda Ramste +7 more

The Clinical Genome Resource (ClinGen) Familial Hypercholesterolemia Variant Curation Expert Panel consensus guidelines for LDLR variant classification

medRxiv(2021)10.1101/2021.03.17.21252755

N/A

0DataRank · unranked

3 citations

Michael A. Iacocca, Lukáš Tichý, Hannah Wand, C. Lisa Kurtz, Heather Zimmermann +23 more

Insulin Resistance and Gender Define a Cell Autonomous Supernetworkof Protein Phosphorylation

Journal of the Endocrine Society(2021)10.1210/jendso/bvab048.912

N/A

0DataRank · unranked

0 citations

Jasmin Lebastchi, Ashok Kumar Jayavelu, Thiago M. Batista, Hui Pan, Jonathan M. Dreyfuss +5 more

Signaling defects associated with insulin resistance in nondiabetic and diabetic individuals and modification by sex

Journal of Clinical Investigation(2021)10.1172/jci151818

N/A

0DataRank · unranked

58 citations

Jasmin Lebastchi, Ashok Kumar Jayavelu, Thiago M. Batista, Hui Pan, Jonathan M. Dreyfuss +5 more

G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

Nature Communications(2022)10.1038/s41467-022-35069-9

N/A

0DataRank · unranked

11 citations

Meng Zhao, Peter‐James H. Zushin, Theresia M. Schnurr, Hyun-Jung Kim, Jiehan Li +8 more

The Clinical Genome Resource (ClinGen) Familial Hypercholesterolemia Variant Curation Expert Panel consensus guidelines for LDLR variant classification

Genetics in Medicine(2021)10.1016/j.gim.2021.09.012

N/A

0DataRank · unranked

168 citations

Michael A. Iacocca, Lukáš Tichý, Hannah Wand, C. Lisa Kurtz, Heather Zimmermann +23 more

G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.25.493489

N/A

0DataRank · unranked

2 citations

Meng Zhao, Peter-James H. Zushin, Theresia M. Schnurr, Hyun‐Jung Kim, Jiehan Li +8 more

X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.29.505759

N/A

0DataRank · unranked

1 citations

Joseph J. Munier, Laurent Vergnes, Carrie B. Wiese, Jenny C. Link, Fahim Abbasi +14 more

Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A–deficient mice

UNC Libraries(2020)10.17615/sg0a-bh46

N/A

0DataRank · unranked

0 citations

John R. Hagaman, Oliver Smithies, Howard A. Rockman, Joshua W. Knowles, Giovanni Esposito +3 more

Joshua W. Knowles

Indexed papers

Top data-sharing exemplar

Papers