Jeffrey D. Rothstein

ORCID: 0000-0003-2001-8470

Also affiliated with Johns Hopkins University, Johns Hopkins Medicine, Lieber Institute for Brain Development

MedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.5Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

Neuron(2023)10.1016/j.neuron.2023.01.010

Top 11%

1.8DataRank

Top 11%90 citations

Ryan G. Lim, Jie Wu, Aaron P. Frank, Loren Ornelas, Lindsay Panther +20 more

Papers

Driven by 53 papers — median percentile 43. Top paper: “Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial”.

Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial

Journal of Neurology Neurosurgery & Psychiatry(2022)10.1136/jnnp-2022-329024

N/A

2.3DataRank · unranked

66 citations

Suzanne Hendrix, Samuel P. Dickson, Newman Knowlton, James D. Berry, Michael A. Elliott +45 more

Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

Neuron(2023)10.1016/j.neuron.2023.01.010

Top 11%

1.8DataRank

Top 11%90 citations

Ryan G. Lim, Jie Wu, Aaron P. Frank, Loren Ornelas, Lindsay Panther +20 more

NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency

Scientific Data(2023)10.1038/s41597-022-01687-7

Top 44%

0.427DataRank

Top 44%11 citations

Vineet Vaibhav, Ronald J. Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo +32 more

Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

Neuron(2025)10.1016/j.neuron.2025.05.022

Top 70%

0.165DataRank

Top 70%2 citations

Ryan G. Lim, Jie Wu, Aaron P. Frank, Loren Ornelas, Lindsay Panther +20 more

Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data

Molecular & Cellular Proteomics(2025)10.1016/j.mcpro.2025.100947

Top 78%

0.104DataRank

Top 78%1 citations

Behrouz Shamsaei, Stephan C. Schürer, Phillip Kogan, Szymon Chojnacki, Michal Kouril +69 more

G 4 C 2 repeat RNA mediates the disassembly of the nuclear pore complex in C9orf72 ALS/FTD

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.13.947721

N/A

0DataRank · unranked

3 citations

Benjamin L. Zaepfel, Lindsey R. Hayes, Boris Fitchman, Yuval Salzberg, Kelly Bowen +7 more

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.01.362269

N/A

0DataRank · unranked

3 citations

Emilda Gomez, Lindsay Panther, Aaron P. Frank, Susan Lei, Berhan Mandefro +40 more

Reactive astrocyte nomenclature, definitions, and future directions

Nature Neuroscience(2021)10.1038/s41593-020-00783-4

N/A

0DataRank · unranked

2396 citations

Elena Galea, András Lakatos, James P. O’Callaghan, Gabor C. Petzold, Alberto Serrano‐Pozo +76 more

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

Nature(2021)10.1038/s41586-020-03045-2

N/A

0DataRank · unranked

1257 citations

Paolo Vignali, Steven J. Mullett, Abigail E. Overacre-Delgoffe, Ronal M. Peralta, Stephanie Grebinoski +12 more

Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS

Science Translational Medicine(2021)10.1126/scitranslmed.abe1923

N/A

0DataRank · unranked

148 citations

Victoria Baskerville, Benjamin L. Zaepfel, Dennis W. Dickson, Frank Rigo, Frank Bennett +3 more

MCT1 Deletion in Oligodendrocyte Lineage Cells Causes Late-Onset Hypomyelination and Axonal Degeneration

Cell Reports(2021)10.1016/j.celrep.2020.108610

N/A

0DataRank · unranked

126 citations

Yevgeniya A. Mironova, Yan Jouroukhin, Jeannie Chew, Svetlana Vidensky, Mohamed H. Farah +5 more

Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD

Nature Communications(2021)10.1038/s41467-021-25082-9

N/A

0DataRank · unranked

102 citations

Malgorzata J. Latallo, Zhe Zhang, Bo Huang, Dmitriy G. Bobrovnikov, Daoyuan Dong +8 more

Macrophage monocarboxylate transporter 1 promotes peripheral nerve regeneration after injury in mice

Journal of Clinical Investigation(2021)10.1172/jci141964

N/A

0DataRank · unranked

85 citations

Joseph V. Passero, Atul Rawat, Xanthe Heifetz Ament, Fang Yang, Svetlana Vidensky +8 more

Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G 4 C 2 ) repeat expansion in vitro and in vivo ALS models

Science Translational Medicine(2021)10.1126/scitranslmed.abd5991

N/A

0DataRank · unranked

80 citations

Haruo Aikawa, Rita Fuerst, Yue Li, Andrei Ursu, Samantha M. Meyer +19 more

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

iScience(2021)10.1016/j.isci.2021.103221

N/A

0DataRank · unranked

51 citations

Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono +92 more

UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction

Cell Reports(2021)10.1016/j.celrep.2021.108925

N/A

0DataRank · unranked

32 citations

Zhe Zhang, Kirstin Maulding, Alyssa N. Coyne, Weiwei Cheng, Lindsey R. Hayes +4 more

The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01228-0

N/A

0DataRank · unranked

23 citations

Jeffrey D. Rothstein, Alyssa N. Coyne

RNA Is a Double-Edged Sword in ALS Pathogenesis

Frontiers in Cellular Neuroscience(2021)10.3389/fncel.2021.708181

N/A

0DataRank · unranked

20 citations

Jeffrey D. Rothstein, Benjamin L. Zaepfel

Nuclear lamina invaginations are not a pathological feature of C9orf72 ALS/FTD

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01150-5

N/A

0DataRank · unranked

13 citations

Jeffrey D. Rothstein, Alyssa N. Coyne

Polyadenylated RNA and RNA-Binding Proteins Exhibit Unique Response to Hyperosmotic Stress

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.809859

N/A

0DataRank · unranked

2 citations

Jeffrey D. Rothstein, Benjamin L. Zaepfel

Nuclear RNA binding regulates TDP-43 nuclear localization and passive nuclear export

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.24.457459

N/A

0DataRank · unranked

4 citations

Benjamin L. Zaepfel, Vasilisa Aksenova, Mary Dasso, Jeffrey D. Rothstein, Petr Kaláb +2 more

Nuclear RNA binding regulates TDP-43 nuclear localization and passive nuclear export

Cell Reports(2022)10.1016/j.celrep.2022.111106

N/A

0DataRank · unranked

116 citations

Benjamin L. Zaepfel, Vasilisa Aksenova, Mary Dasso, Jeffrey D. Rothstein, Petr Kaláb +2 more

Nuclear pore complexes — a doorway to neural injury in neurodegeneration

Nature Reviews Neurology(2022)10.1038/s41582-022-00653-6

N/A

0DataRank · unranked

96 citations

Jeffrey D. Rothstein, Alyssa N. Coyne

Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins

Science Translational Medicine(2022)10.1126/scitranslmed.abq3215

N/A

0DataRank · unranked

23 citations

Quinlan T. Mewborne, Amandeep Girdhar, Udit Sheth, Alyssa N. Coyne, Ritika Punathil +23 more

Astrocyte MCT1 expression does not contribute to the axonal degenerative phenotype observed with ubiquitous MCT1 depletion

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.27.518094

N/A

0DataRank · unranked

0 citations

Emily G. Thompson, Balaji G. Vijayakumar, Erica R. Kent, Sean Miller, Svetlana Vidensky +3 more

G2C4 targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in human C9orf72 ALS/FTD induced pluripotent stem cell derived neurons

Acta Neuropathologica(2023)10.1007/s00401-023-02652-3

N/A

0DataRank · unranked

38 citations

Victoria Baskerville, Sampath Rapuri, Emma Mehlhop, Paymaan Jafar‐Nejad, Frank Rigo +5 more

Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit

Neurology and Therapy(2023)10.1007/s40120-023-00548-8

N/A

0DataRank · unranked

34 citations

Bryan J. Traynor, Janice Robertson, Ludo Van Den Bosch, Sami J. Barmada, Clive N. Svendsen +49 more

Highly variable molecular signatures of TDP-43 loss of function are associated with nuclear pore complex injury in a population study of sporadic ALS patient iPSNs

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.12.571299

N/A

0DataRank · unranked

17 citations

Caroline Warlick, Alyssa N. Coyne, Jeffrey D. Rothstein

G 2 C 4 targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in C9orf72 ALS/FTD human neurons

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.26.546581

N/A

0DataRank · unranked

0 citations

Victoria Baskerville, Sampath Rapuri, Emma Mehlhop, Paymaan Jafar‐Nejad, Frank Rigo +5 more

Monocarboxylate transporters facilitate succinate uptake into brown adipocytes

Nature Metabolism(2024)10.1038/s42255-024-00981-5

N/A

0DataRank · unranked

32 citations

Sally Winther, Nhien Tran, Haopeng Xiao, Josefine Jakob, Ryan Garrity +7 more

Nuclear pore dysfunction and disease: a complex opportunity

Nucleus(2024)10.1080/19491034.2024.2314297

N/A

0DataRank · unranked

21 citations

Jeffrey D. Rothstein, Charlotte M. Fare

Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data

Cell Genomics(2024)10.1016/j.xgen.2024.100679

N/A

0DataRank · unranked

6 citations

Cleide Dos Santos Souza, Ruth Chia, Selina N. Beal, Ileana Lorenzini, Ruili Huang +92 more

Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes

Neuron(2024)10.1016/j.neuron.2024.10.007

N/A

0DataRank · unranked

7 citations

Jenny H To, Vaishali Gautam, Lena Annika Street, Chloe Nguyen, Jack T. Naritomi +19 more

A robust evaluation of TDP-43, poly GP, cellular pathology and behavior in an AAV-C9ORF72 (G4C2)66 mouse model

Acta Neuropathologica Communications(2024)10.1186/s40478-024-01911-y

N/A

0DataRank · unranked

4 citations

Olivia Spead, Sigvard Åkerman, Carrie Curcio, Benjamin L. Zaepfel, Erica R. Kent +7 more

Investigating the Protective Role of the Mitochondrial 2158 T > C Variant in Parkinson's Disease

Movement Disorders(2024)10.1002/mds.29892

N/A

0DataRank · unranked

2 citations

Vesna van Midden, Sigvard Åkerman, Mary B. Makarious, Global Parkinson's Genetics Program, Jeffrey D. Rothstein +3 more

Counter-regulation of RNA stability by UPF1 and TDP43

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.31.578310

N/A

0DataRank · unranked

5 citations

Caroline Hsieh, Xingli Li, Megan Dykstra, Jacob Waksmacki, Christopher Altheim +7 more

A robust evaluation of TDP-43, poly GP, cellular pathology and behavior in a AAV-C9ORF72 (G 4 C 2 ) 66 mouse model

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.27.607409

N/A

0DataRank · unranked

0 citations

Olivia Spead, Sigvard Åkerman, Carrie Curcio, Benjamin L. Zaepfel, Erica R. Kent +7 more

A robust evaluation of TDP-43, poly GP, cellular pathology and behavior in a AAV- C9ORF72 (G 4 C 2 ) 66 mouse model

Research Square(2024)10.21203/rs.3.rs-5221595/v1

N/A

0DataRank · unranked

0 citations

Olivia Spead, Sigvard Åkerman, Carrie Curcio, Benjamin L. Zaepfel, Erica R. Kent +7 more

The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging

Nature Medicine(2025)10.1038/s41591-025-03834-0

N/A

0DataRank · unranked

95 citations

Rowan Saloner, Jacob W. Vogel, Varsha Krish, Gamal Abdel-Azim, Muhammad Ali +47 more

APOE ε4 carriers share immune-related proteomic changes across neurodegenerative diseases

Nature Medicine(2025)10.1038/s41591-025-03835-z

N/A

0DataRank · unranked

59 citations

Erik C. B. Johnson, Laura Winchester, Keenan A. Walker, Heather Wilkins, Terri G. Thompson +8 more

Sporadic ALS induced pluripotent stem cell derived neurons reveal hallmarks of TDP-43 loss of function

Nature Communications(2025)10.1038/s41467-025-62482-7

N/A

0DataRank · unranked

14 citations

Olivia Keeley, Caroline Warlick, Timothy M. Miller, Cindy V. Ly, Jonathan D. Glass +2 more

Visualizing nuclear pore complex plasticity with pan-expansion microscopy

The Journal of Cell Biology(2025)10.1083/jcb.202409120

N/A

0DataRank · unranked

11 citations

Emma Carley, Alyssa N. Coyne, Jeffrey D. Rothstein, C. Patrick Lusk, Megan C. King +1 more

Divergent and convergent TMEM106B pathology in murine models of neurodegeneration and human disease

Acta Neuropathologica Communications(2025)10.1186/s40478-025-02087-9

N/A

0DataRank · unranked

4 citations

Suleyman C. Akerman, Charlotte M. Fare, Linhao Ruan, Svetlana Vidensky, Lyudmila Mamedova +4 more

Biobank-scale genetic characterization of Alzheimer’s disease and related dementias across diverse ancestries

Nature Communications(2025)10.1038/s41467-025-62108-y

N/A

0DataRank · unranked

3 citations

Fulya Akçimen, Spencer Grant, Sigvard Åkerman, Paul Suhwan Lee, Faraz Faghri +10 more

Identification of a Subpopulation of Astrocyte Progenitor Cells in the Neonatal Subventricular Zone: Evidence that Migration is Regulated by Glutamate Signaling

Neurochemical Research(2025)10.1007/s11064-024-04326-2

N/A

0DataRank · unranked

1 citations

Alain M. Guillem, Isabella Song, Michael V. Gonzalez, Hajime Takano, Esha Parikh +4 more

Corrigendum to “Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data”

Molecular & Cellular Proteomics(2025)10.1016/j.mcpro.2025.100995

N/A

0DataRank · unranked

0 citations

Behrouz Shamsaei, Stephan C. Schürer, Phillip Kogan, Szymon Chojnacki, Michal Kouril +68 more

Astrocyte MCT1 Expression Does Not Contribute to the Axonal Degenerative Phenotype Observed With Ubiquitous MCT1 Depletion

Glia(2025)10.1002/glia.70113

N/A

0DataRank · unranked

0 citations

Emily G. Thompson, Olivia Spead, Balaji G. Vijayakumar, Erica R. Kent, Sean Miller +5 more

G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD

Neuron(2020)10.1016/j.neuron.2020.06.027

N/A

0DataRank · unranked

169 citations

Benjamin L. Zaepfel, Lindsey R. Hayes, Boris Fitchman, Yuval Salzberg, En‐Ching Luo +10 more

Mapping the circulating proteome across neurodegeneration: A harmonized, consortium-scale framework for uncovering molecular pathophysiology

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.09.693329

N/A

0DataRank · unranked

0 citations

Lijun An, Laura Winchester, Jacob Vogel, Heather M. Wilkins, Jeffrey M. Burns +7 more

C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import

eLife(2020)10.7554/elife.51685

N/A

0DataRank · unranked

139 citations

Lauren Duan, Kelly Bowen, Petr Kaláb, Jeffrey D. Rothstein, Lindsey R. Hayes

TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS

eLife(2020)10.7554/elife.59419

N/A

0DataRank · unranked

78 citations

Kirstin Maulding, Kai Ruan, Mümine Şentürk, Jonathan C. Grima, Hyun Sung +9 more

Amyotrophic lateral sclerosis care and research in the United States during the COVID‐19 pandemic: Challenges and opportunities

Muscle & Nerve(2020)10.1002/mus.26989

N/A

0DataRank · unranked

59 citations

James D. Berry, Robert H. Baloh, Nathan Carberry, Merit Cudkowicz, Brixhilda Dedi +10 more

Absence of Survival and Motor Deficits in 500 Repeat C9ORF72 BAC Mice

Neuron(2020)10.1016/j.neuron.2020.08.009

N/A

0DataRank · unranked

57 citations

Brett M. Morrison, Xanthe Heifetz Ament, C. Ron Cantrell, Joanie Mok, Pierce Eggan +5 more

Jeffrey D. Rothstein

Indexed papers

Top data-sharing exemplar

Papers