🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Richard M. O’Brien

Vanderbilt University

ORCID: 0000-0003-2153-9761

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 9 papers. Top paper: “Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers”.

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

Acta Neuropathologica(2017)10.1007/s00401-017-1685-y

N/A

0.829DataRank · unranked

251 citations

Zeran Li, Manav Kapoor, Oscar Harari, Kathleen Black, David Carrell +44 more

Ins1-Cre and Ins1-CreER Gene Replacement Alleles Are Susceptible To Silencing By DNA Hypermethylation

Endocrinology(2020)10.1210/endocr/bqaa054

N/A

0DataRank · unranked

74 citations

Kristy Ou, Matthew W. Haemmerle, Teguru Tembo, Andrew Yuhas, Lindsey Carboneau +7 more

Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101534

N/A

0DataRank · unranked

18 citations

Karin J. Bosma, Derek P. Claxton, James K. Oeser, Kritika Singh, Lindsay B. Breidenbach +4 more

Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101729

N/A

0DataRank · unranked

29 citations

Arya Y. Nakhe, Deveena R. Banerjee, Emily M. Overway, Karin J. Bosma, Jonah C. Rosch +7 more

Identification of structural motifs critical for human G6PC2 function informed by sequence analysis and an AlphaFold2-predicted model

Bioscience Reports(2023)10.1042/bsr20231851

N/A

0DataRank · unranked

4 citations

Derek P. Claxton, James K. Oeser, Richard M. O’Brien, Emily M. Hawes

Molecular mechanisms of catalytic inhibition for active site mutations in glucose-6-phosphatase catalytic subunit 1 linked to glycogen storage disease

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.13.532485

N/A

0DataRank · unranked

1 citations

Richard A. Stein, Jonathan H. Sheehan, Emily M. Hawes, Richard M. O’Brien, Emad Tajkhorshid +2 more

The role of glucose-6-phosphatase activity in glucose homeostasis and its potential for diabetes therapy

Trends in Molecular Medicine(2024)10.1016/j.molmed.2024.09.005

N/A

0DataRank · unranked

26 citations

Hwee Hui Lau, Essam M. Abdelalim, Chin Meng Khoo, Richard M. O’Brien, E. Shyong Tai +2 more

Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model

PNAS Nexus(2024)10.1093/pnasnexus/pgae036

N/A

0DataRank · unranked

7 citations

Richard A. Stein, Jonathan H. Sheehan, Emily M. Hawes, Richard M. O’Brien, Emad Tajkhorshid +2 more

Biochemical and metabolic characterization of a G6PC2 inhibitor

Biochimie(2024)10.1016/j.biochi.2024.02.012

N/A

0DataRank · unranked

4 citations

Mohsin Rahim, Zeinab Haratipour, Abigail R. Orun, M. O'Rourke, James K. Oeser +6 more