Brian T. Layden

Also affiliated with University of Illinois Chicago, University of Chicago, Jesse Brown VA Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 7%percentile

0.104Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

MOMMI-MP: A Comprehensive Database for Integrated Analysis of Metabolic and Microbiome Profiling of Mouse Pregnancy

Preprints.org(2022)10.20944/preprints202212.0378.v1

Top 78%

0.104DataRank

Top 78%1 citations

Medha Priyadarshini, Derek Reiman, Brian T. Layden, Yang Dai, Kaustubh Pachpor

Papers

Driven by 57 papers — median percentile 22. Top paper: “Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection”.

Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection

Gut Microbes(2022)10.1080/19490976.2022.2105609

N/A

0.604DataRank · unranked

55 citations

Katherine Z. Sanidad, Serena Lucotti, Carolin M. Lieber, Robert M. Cox, Aparna Ananthanarayanan +21 more

The Notch-PDGFRβ axis suppresses brown adipocyte progenitor differentiation in early post-natal mice

Developmental Cell(2024)10.1016/j.devcel.2024.03.012

N/A

0.589DataRank · unranked

9 citations

Shaolei Xiong, Ruoci Hu, Zilai Wang, Jooman Park, Yanyu Qian +12 more

Lipidomic profiling of human adiposomes identifies specific lipid shifts linked to obesity and cardiometabolic risk

JCI Insight(2025)10.1172/jci.insight.191872

N/A

0.425DataRank · unranked

16 citations

Imaduddin Mirza, Elsayed Metwally, Mohammed Morsy, Giorgia Scichilone, Monica C. Asada +7 more

Estrogen counteracts age-related decline in beige adipogenesis through the NAMPT-regulated ER stress response

Nature Aging(2024)10.1038/s43587-024-00633-z

N/A

0.416DataRank · unranked

15 citations

Ruoci Hu, Yanyu Qian, Shaolei Xiong, Asma Sana El-Sabbagh, Meram Ibrahim +14 more

Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: The METS-Microbiome Study

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.21.533195

N/A

0.345DataRank · unranked

9 citations

Candice Choo-Kang, Maria Gjerstad Maseng, Sonya Donato, Pascal Bovet, Kweku Bedu-Addo +10 more

Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy

Investigative Ophthalmology & Visual Science(2024)10.1167/iovs.65.14.39

N/A

0.330DataRank · unranked

8 citations

Poorna C. R. Yalagala, Jason C. Park, Guangying Ma, Zeenat Farooq, Basma Baccouche +7 more

Toxic metals impact gut microbiota and metabolic risk in five African-origin populations

Gut Microbes Reports(2025)10.1080/29933935.2025.2481442

N/A

0.241DataRank · unranked

4 citations

Candice Choo-Kang, Luyu Wang, Lina Issa, Jack A. Gilbert, Gertrude Ecklu-Mensah +13 more

Objectively measured moderate-to-vigorous physical activity does not attenuate prospective weight gain among african-origin adults spanning the epidemiological transition

Scientific Reports(2025)10.1038/s41598-025-85383-7

N/A

0.208DataRank · unranked

3 citations

Candice Choo-Kang, Larske M. Soepnel, Hayli Geffen, Chad Africa, Asanda Mtintsilana +19 more

Obesity‐Associated Adiposomes Promote Vascular Smooth Muscle Cell Hypercontractility

Comprehensive physiology(2025)10.1002/cph4.70053

N/A

0.165DataRank · unranked

2 citations

Imaduddin Mirza, Mohammed Morsy, Sarah M. Mostafa, Francesco M. Bianco, Chandra Hassan +7 more

MOMMI-MP: A Comprehensive Database for Integrated Analysis of Metabolic and Microbiome Profiling of Mouse Pregnancy

Preprints.org(2022)10.20944/preprints202212.0378.v1

Top 78%

0.104DataRank

Top 78%1 citations

Medha Priyadarshini, Derek Reiman, Brian T. Layden, Yang Dai, Kaustubh Pachpor

The utility of physical activity questionnaires among African origin populations; lost in translation?

Research Square(2024)10.21203/rs.3.rs-5529358/v1

N/A

0.104DataRank · unranked

1 citations

Candice Choo-Kang, Larske M. Soepnel, Hayli Geffen, Asanda Mtintsilana, Chad Africa +16 more

Gestational insulin resistance is mediated by the gut microbiome-indoleamine 2,3-dioxygenase axis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.21.453234

N/A

0DataRank · unranked

3 citations

Guadalupe Navarro, Derek Reiman, Anukriti Sharma, Kai Xu, Kristen Lednovich +12 more

The hexokinase “HKDC1” interaction with the mitochondria is essential for hepatocellular carcinoma progression

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.10.468146

N/A

0DataRank · unranked

1 citations

Alexander R. Terry, Medha Priyadarshini, Grace Guzman, José Córdoba‐Chacón, Issam Ben‐Sahra +3 more

Central and peripheral regulations mediated by short-chain fatty acids on energy homeostasis

Translational research(2022)10.1016/j.trsl.2022.06.003

N/A

0DataRank · unranked

63 citations

Kristen Lednovich, Kai Xu, Chioma Nnyamah, Brian T. Layden, Pingwen Xu +1 more

Gestational Insulin Resistance Is Mediated by the Gut Microbiome–Indoleamine 2,3-Dioxygenase Axis

Gastroenterology(2022)10.1053/j.gastro.2022.01.008

N/A

0DataRank · unranked

38 citations

Guadalupe Navarro, Derek Reiman, Anukriti Sharma, Kai Xu, Kristen Lednovich +15 more

Enterocyte HKDC1 Modulates Intestinal Glucose Absorption in Male Mice Fed a High-fat Diet

Endocrinology(2022)10.1210/endocr/bqac050

N/A

0DataRank · unranked

13 citations

Barton Wicksteed, Brian T. Layden, Joseph L. Zapater

Utility of silhouette showcards to assess adiposity in three countries across the epidemiological transition

PLOS Global Public Health(2022)10.1371/journal.pgph.0000127

N/A

0DataRank · unranked

4 citations

Pascal Bovet, Candice Choo-Kang, Kweku Bedu-Addo, Terrence Forrester, Jack A. Gilbert +10 more

Signalling cognition: the gut microbiota and hypothalamic-pituitary-adrenal axis

Frontiers in Endocrinology(2023)10.3389/fendo.2023.1130689

N/A

0DataRank · unranked

364 citations

Brian T. Layden, Lara R. Dugas, Jody Rusch

Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study

Nature Communications(2023)10.1038/s41467-023-40874-x

N/A

0DataRank · unranked

116 citations

Candice Choo-Kang, Maria Gjerstad Maseng, Sonya Donato, Pascal Bovet, Bharathi Viswanathan +14 more

Opportunistic detection of type 2 diabetes using deep learning from frontal chest radiographs

Nature Communications(2023)10.1038/s41467-023-39631-x

N/A

0DataRank · unranked

59 citations

Stephen M. Borstelmann, Ramana Mantravadi, Zachary Zaiman, K.J. Thomas, Brandon Price +20 more

Aiding Cancer’s “Sweet Tooth”: Role of Hexokinases in Metabolic Reprogramming

Life(2023)10.3390/life13040946

N/A

0DataRank · unranked

26 citations

Hagar Ismail, Sheraz Ahmad Bhat, Brian T. Layden, Md. Wasim Khan, Zeenat Farooq

miR‐10b‐5p rescues leaky gut linked with gastrointestinal dysmotility and diabetes

United European Gastroenterology Journal(2023)10.1002/ueg2.12463

N/A

0DataRank · unranked

19 citations

Rajan Singh, Se Eun Ha, Zhuqing Wang, Byungchang Jin, Mariah Ha +11 more

Improvement of retinal function in Alzheimer disease-associated retinopathy by dietary lysophosphatidylcholine-EPA/DHA

Scientific Reports(2023)10.1038/s41598-023-36268-0

N/A

0DataRank · unranked

18 citations

Jason C. Park, J. Jason McAnany, Tae-Hoon Kim, Guangying Ma, Xincheng Yao +6 more

Intestinal FFA2 promotes obesity by altering food intake in Western diet-fed mice

Journal of Endocrinology(2023)10.1530/joe-23-0184

N/A

0DataRank · unranked

7 citations

Sophie Gough, Medha Priyadarshini, Nupur Pandya, Chioma Nnyamah, Kai Xu +8 more

Stress and human health in diabetes: A report from the 19th Chicago Biomedical Consortium symposium

Journal of Clinical and Translational Science(2023)10.1017/cts.2023.646

N/A

0DataRank · unranked

1 citations

Rohit N. Kulkarni, Pingwen Xu, Tina Drossos, Krista A Varady, Kristen L. Knutson +16 more

Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: The METS-Microbiome Study

Research Square(2023)10.21203/rs.3.rs-2791107/v1

N/A

0DataRank · unranked

0 citations

Gertrude Ecklu-Mensah, Maria Gjerstad Maseng, Sonya Donato, Candice Coo-Kang, Lara R. Dugas +10 more

Abnormalities in microbiota/butyrate/FFAR3 signaling in aging gut impair brain function

JCI Insight(2024)10.1172/jci.insight.168443

N/A

0DataRank · unranked

62 citations

Shalini Jain, Bo Wang, Shaohua Wang, Brandi Miller, Jea-Young Lee +8 more

HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2306454120

N/A

0DataRank · unranked

52 citations

Koji Yamano, Kenichi Yamamoto, Hitomi Yamamoto‐Imoto, Satoshi Minami, Takeshi Yamamoto +17 more

The primate gut microbiota contributes to interspecific differences in host metabolism

Microbial Genomics(2024)10.1099/mgen.0.001322

N/A

0DataRank · unranked

5 citations

Sahana Kuthyar, Won Lee, Derek Reiman, Hongmei Jiang, Sriram Chitta +15 more

Silhouette showcards confirm altered obesity-associated body image perception in international cohort study of African-origin populations

BMJ Open(2024)10.1136/bmjopen-2022-065498

N/A

0DataRank · unranked

2 citations

Tyler Reese, Lisa K. Micklesfield, Pascal Bovet, Kweku Bedu-Addo, Terrence Forrester +10 more

The relationship between leptin-to-adiponectin ratio and HOMA-IR and metabolic syndrome in five African-origin populations

International Journal of Obesity(2024)10.1038/s41366-024-01655-8

N/A

0DataRank · unranked

2 citations

Julianne Jorgensen, Julia Zeng, Candice Choo-Kang, Joseph L. Zapater, Kweku Bedu-Addo +10 more

Sex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment

Sleep Epidemiology(2024)10.1016/j.sleepe.2024.100091

N/A

0DataRank · unranked

2 citations

Arron T.L. Correia, Laura C. Roden, Estelle V. Lambert, Brian T. Layden, Sirimon Reutrakul +5 more

Toxic Metals Impact Gut Microbiota and Metabolic Risk in Five African-Origin Populations

medRxiv(2024)10.1101/2024.10.07.24315016

N/A

0DataRank · unranked

2 citations

Candice Choo-Kang, Luyu Wang, Lina Issa, Jack A. Gilbert, Gertrude Ecklu-Mensah +13 more

β cell acetate production and release are negligible

Islets(2024)10.1080/19382014.2024.2339558

N/A

0DataRank · unranked

0 citations

Chioma Nnyamah, Nupur Pandya, Nadia Sweis, Irene Corona‐Avila, Medha Priyadarshini +3 more

Objectively measured moderate-to-vigorous physical activity does not attenuate prospective weight gain among African-origin adults spanning the epidemiological transition.

Research Square(2024)10.21203/rs.3.rs-5043485/v1

N/A

0DataRank · unranked

0 citations

Candice Choo-Kang, Larske M. Soepnel, Hayli Geffen, Chad Africa, Asanda Mtintsilana +18 more

Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection

Cell Host & Microbe(2025)10.1016/j.chom.2024.12.017

N/A

0DataRank · unranked

25 citations

Sarah de Oliveira, Tihana Tršan, Silvia Penati, Susan Gilfillan, Siyan Cao +10 more

Adiposome Proteomics Uncover Molecular Signatures of Cardiometabolic Risk in Obese Individuals

Proteomes(2025)10.3390/proteomes13030039

N/A

0DataRank · unranked

6 citations

Monica C. Asada, Imaduddin Mirza, Mohammed Morsy, Amro Mostafa, Francesco M. Bianco +6 more

Gut Microbiota–Derived Lipopolysaccharides and Short‐Chain Fatty Acids Regulate Immune Responses via FFAR2/FFAR3 in Lung Ischemia–Reperfusion Injury

Annals of the New York Academy of Sciences(2025)10.1111/nyas.70043

N/A

0DataRank · unranked

4 citations

Thien N. M. Doan, Xiaoli Tian, Tomohiro Chaki, Jade J. Yeh, Brian T. Layden +2 more

Association of Pancreas Volume With Adverse Clinical Outcomes

Journal of the American Heart Association(2025)10.1161/jaha.125.042348

N/A

0DataRank · unranked

3 citations

Celestin Missikpode, O Martinez, Ashish Verma, Runqi Zhao, Sophie E. Claudel +8 more

Hemoglobin S Promotes Glycemic Dysregulation in a Mouse Model of Human Sickle Cell Disease

Endocrinology(2025)10.1210/endocr/bqaf082

N/A

0DataRank · unranked

1 citations

Seth Thomas Nicholoff, Nadia Sweis, Santosh L. Saraf, Brian T. Layden, Joseph L. Zapater

Association of pancreas fat fraction with adverse kidney and cardiovascular outcomes

Clinical Kidney Journal(2025)10.1093/ckj/sfaf310

N/A

0DataRank · unranked

1 citations

Martina Isabel Salud, Celestin Missikpode, Omar Garcia Martinez, Ashish Verma, Runqi Zhao +9 more

Validating an Electronic Health Record Algorithm for Diabetes Screening Eligibility in the Emergency Department

Western Journal of Emergency Medicine(2025)10.5811/westjem.20548

N/A

0DataRank · unranked

0 citations

Janet Lin, Brian T. Layden, Yuval Eisenberg, Kirstie K. Danielson, Ruth Pobee +7 more

An ecological analysis of sleep health across five African-origin populations spanning the epidemiologic transition

Sleep Health(2025)10.1016/j.sleh.2025.02.002

N/A

0DataRank · unranked

0 citations

Stephanie J. Crowley, Sirimon Reutrakul, Dale E. Rae, Estelle V. Lambert, Nandipha Sinyanya +16 more

Combined Prebiotic Dietary Inulin and VSL#3 Probiotics Modulate Gut Metabolites to Improve Energy Balance and Glucose Metabolism in Diet-Induced Obese Mice

Current Developments in Nutrition(2025)10.1016/j.cdnut.2025.107120

N/A

0DataRank · unranked

0 citations

Ángel Lee, Shari Wang, Robin Altman, Meifan Zhang, CAELEY BRYAN +5 more

Pancreatic β-cell FFA2 deficiency suppresses multiple low dose streptozotocin induced diabetes in male mice

Communications Biology(2025)10.1038/s42003-025-08787-1

N/A

0DataRank · unranked

0 citations

Prabhakaran Kumar, Sophia R. Chang Stauffer, Husena M. Electricwala, Bellur S. Prabhakar, Irene Corona‐Avila +4 more

Expression of Free Fatty Acid Receptor 2 by Dendritic Cells Prevents Their Expression of Interleukin 27 and Is Required for Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice

Gastroenterology(2020)10.1053/j.gastro.2019.12.027

N/A

0DataRank · unranked

102 citations

Eunyoung Chun, Sena Bae, Caitlin A. Brennan, Carey Ann Gallini Comeau, Jessica Lang +8 more

Adiposome Lipidomic Shifts Following Bariatric Surgery in Association With Weight Loss and Cardiometabolic Benefit

The Journal of Clinical Endocrinology & Metabolism(2025)10.1210/clinem/dgaf586

N/A

0DataRank · unranked

0 citations

Lundon C. Burton, Imaduddin Mirza, Mohammed Morsy, Giorgia Scichilone, Amro Mostafa +8 more

Identification of a periodontal pathogen and bihormonal cells in pancreatic islets of humans and a mouse model of periodontitis

Scientific Reports(2020)10.1038/s41598-020-65828-x

N/A

0DataRank · unranked

31 citations

Péter T. Tóth, Klara Valyi‐Nagy, Tibor Vályi-Nagy, Stefan J. Green, Rosann S. Marattil +8 more

Predictors of HbA1c among Adipocytokine Biomarkers in African-American Men with Varied Glucose Tolerance

Biomedicines(2020)10.3390/biomedicines8110520

N/A

0DataRank · unranked

1 citations

Arfana Akbar, Brian T. Layden, Yuval Eisenberg, Medha Priyadarshini, Jeffrey A. Borgia +4 more

Predictors of HbA1c among adipocytokine biomarkers in African American men with varied glucose tolerance

Research Square(2020)10.21203/rs.3.rs-51156/v1

N/A

0DataRank · unranked

0 citations

Arfana Akbar, Brian T. Layden, Yuval Eisenberg, Medha Priyadarshini, Jeffrey A. Borgia +4 more

Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior

Molecular Metabolism(2021)10.1016/j.molmet.2021.101350

N/A

0DataRank · unranked

101 citations

Chaitanya K. Gavini, Jason Jesse, Grégory Aubert, Emily Gornick, Raiza Bonomo +4 more

MiMeNet: Exploring microbiome-metabolome relationships using neural networks

PLoS Computational Biology(2021)10.1371/journal.pcbi.1009021

N/A

0DataRank · unranked

78 citations

Brian T. Layden, Yang Dai, Derek Reiman

Hepatocyte-Specific Loss of PPARγ Protects Mice From NASH and Increases the Therapeutic Effects of Rosiglitazone in the Liver

Cellular and Molecular Gastroenterology and Hepatology(2021)10.1016/j.jcmgh.2021.01.003

N/A

0DataRank · unranked

69 citations

Carolina Pusec, Gregory H. Norris, Adam De Jesus, Alberto Díaz‐Ruiz, Jose Muratalla +5 more

Hexokinase domain-containing protein-1 in metabolic diseases and beyond

Trends in Endocrinology and Metabolism(2021)10.1016/j.tem.2021.10.006

N/A

0DataRank · unranked

60 citations

Kristen Lednovich, Md. Wasim Khan, Carolina Pusec, Brian T. Layden, Joseph L. Zapater

Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development

EBioMedicine(2021)10.1016/j.ebiom.2021.103287

N/A

0DataRank · unranked

31 citations

Md. Wasim Khan, Manel Benaissa, Oleksii Dubrovskyi, Martha Ackerman-Berrier, Mary Jo LaDu +3 more

Gut microbiota alterations in response to sleep length among African-origin adults

PLoS ONE(2021)10.1371/journal.pone.0255323

N/A

0DataRank · unranked

31 citations

Candice Choo-Kang, Sirimon Reutrakul, Stephanie J. Crowley, Dale E. Rae, Kweku Bedu-Addo +11 more

FFAR from the Gut Microbiome Crowd: SCFA Receptors in T1D Pathology

Metabolites(2021)10.3390/metabo11050302

N/A

0DataRank · unranked

15 citations

Kristen Lednovich, Kai Xu, Sophie Gough, Barton Wicksteed, Brian T. Layden +1 more

Brian T. Layden

Indexed papers

Top data-sharing exemplar

Papers