Robert J. Linhardt

Biochemistry, Genetics and Molecular BiologyChemistryAgricultural and Biological Sciences

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 132 papers. Top paper: “Apolipoprotein E Recognizes Alzheimer's Disease Associated 3‐O Sulfation of Heparan Sulfate”.

Apolipoprotein E Recognizes Alzheimer's Disease Associated 3‐O Sulfation of Heparan Sulfate

Angewandte Chemie International Edition(2023)10.1002/anie.202212636

N/A

0.879DataRank · unranked

24 citations

Yanan Zhu, Guowei Su, Jing Zhao, Ashely Canning, James M. Gibson +9 more

Designer DNA nanostructures for viral inhibition

Nature Protocols(2022)10.1038/s41596-021-00641-y

N/A

0.878DataRank · unranked

30 citations

Keith Fraser, Lili Kuo, Neha Chauhan, Addison T. Adrian, Fuming Zhang +4 more

Advances in the preparation and synthesis of heparin and related products

Drug Discovery Today(2020)10.1016/j.drudis.2020.09.011

N/A

0.686DataRank · unranked

96 citations

Robert J. Linhardt, Sultan Nacak Baytaş

Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure

Science Translational Medicine(2020)10.1126/scitranslmed.aav8075

N/A

0.677DataRank · unranked

90 citations

Yongmei Xu, Erica Sparkenbaugh, Miaomiao Li, Xiaorui Han, Xing Zhang +16 more

Functionalization of Electrospun Nanofibers and Fiber Alignment Enhance Neural Stem Cell Proliferation and Neuronal Differentiation

Frontiers in Bioengineering and Biotechnology(2020)10.3389/fbioe.2020.580135

N/A

0.650DataRank · unranked

75 citations

Carlos A. V. Rodrigues, Inês Ferreira, Maria Margarida Diogo, Robert J. Linhardt, Joaquim M. S. Cabral +2 more

Elucidating the unusual reaction kinetics of D-glucuronyl C5-epimerase

Glycobiology(2020)10.1093/glycob/cwaa035

N/A

0.638DataRank · unranked

12 citations

Elena E. Paskaleva, Troy Vargason, Ke Xia, Scott A. McCallum, Robert J. Linhardt +2 more

Hyphenated techniques for the analysis of heparin and heparan sulfate

Analytical and Bioanalytical Chemistry(2011)10.1007/s00216-010-4117-6

N/A

0.626DataRank · unranked

64 citations

Kemal Solakyildirim, Yuqing Chang, Robert J. Linhardt, Bo Yang

Kinetic and Structural Aspects of Glycosaminoglycan–Monkeypox Virus Protein A29 Interactions Using Surface Plasmon Resonance

Molecules(2022)10.3390/molecules27185898

N/A

0.614DataRank · unranked

59 citations

Peng He, Yuefan Song, Shuihong Cheng, Robert J. Linhardt, Jonathan S. Dordick +3 more

N-glycolyl chondroitin synthesis using metabolically engineered E. coli

AMB Express(2020)10.1186/s13568-020-01084-6

N/A

0.566DataRank · unranked

11 citations

Sultan Nacak Baytaş, Ke Xia, Abinaya Badri, Wenqin He, Ajit Varki +3 more

The Sulfation Code of Tauopathies: Heparan Sulfate Proteoglycans in the Prion Like Spread of Tau Pathology

Frontiers in Molecular Biosciences(2021)10.3389/fmolb.2021.671458

N/A

0.561DataRank · unranked

41 citations

Jing Zhao, Xinyue Liu, Fuming Zhang, Jian Liu, Lianchun Wang +3 more

High density fermentation of probiotic E. coli Nissle 1917 towards heparosan production, characterization, and modification

Applied Microbiology and Biotechnology(2021)10.1007/s00253-020-11079-9

N/A

0.546DataRank · unranked

37 citations

Li Fu, Paul Brodfuerer, Jonathan S. Dordick, Robert J. Linhardt, Payel Datta

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate

Pharmaceuticals(2022)10.3390/ph15020258

N/A

0.538DataRank · unranked

35 citations

Peng He, André L. Rodrigues, Walter Jeske, Ritesh Tandon, John T. Bates +5 more

Digestibility of squash polysaccharide under simulated salivary, gastric and intestinal conditions and its impact on short-chain fatty acid production in type-2 diabetic rats

Carbohydrate Polymers(2020)10.1016/j.carbpol.2020.115904

N/A

0.538DataRank · unranked

35 citations

Guimei Liu, Fuming Zhang, Quanhong Li, Robert J. Linhardt, Liang Li

Circadian control of heparan sulfate levels times phagocytosis of amyloid beta aggregates

PLoS Genetics(2022)10.1371/journal.pgen.1009994

N/A

0.533DataRank · unranked

34 citations

Yanlei Yu, Cooper A. Urban, Guo Fu, Chunyu Wang, Fuming Zhang +3 more

Heparin Specifically Inhibits CRISPR/Cas12 Activation, Enabling Ultrasensitive Heparin Detection and Gene Editing Regulation

Analytical Chemistry(2024)10.1021/acs.analchem.4c00403

N/A

0.520DataRank · unranked

31 citations

Xinlan Bian, Zhirun Ji, Muhammad Sohail, Fuming Zhang, Robert J. Linhardt +3 more

Site-selective reactions for the synthesis of glycoconjugates in polysaccharide vaccine development

Carbohydrate Polymers(2020)10.1016/j.carbpol.2019.115643

N/A

0.489DataRank · unranked

25 citations

Meng Qiao, Xing Zhang, Robert J. Linhardt, Lei Lin

SPR Sensor-Based Analysis of the Inhibition of Marine Sulfated Glycans on Interactions between Monkeypox Virus Proteins and Glycosaminoglycans

Marine Drugs(2023)10.3390/md21050264

N/A

0.477DataRank · unranked

23 citations

Deling Shi, Yunran Li, Ke Xia, Seon Beom Kim, Rohini Dwivedi +6 more

Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides

Scientific Reports(2020)10.1038/s41598-020-72645-9

N/A

0.470DataRank · unranked

22 citations

Chao Cai, Kanin Wichapong, Sayantan Bhaduri, Nicola L. B. Pohl, Robert J. Linhardt +3 more

Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity

Oncotarget(2020)10.18632/oncotarget.27634

N/A

0.464DataRank · unranked

21 citations

Leo Feferman, Xiaorui Han, Ke Xia, Fuming Zhang, Robert J. Linhardt +2 more

Cholesterol Chip for the Study of Cholesterol–Protein Interactions Using SPR

Biosensors(2022)10.3390/bios12100788

N/A

0.462DataRank · unranked

7 citations

Shannon Faris, Reddy Sudheer Sagabala, Payel Datta, Zihan Xu, Brian P. Callahan +5 more

Sulfated glycosaminoglycans are host epithelial cell targets of the Candida albicans toxin candidalysin

Nature Microbiology(2024)10.1038/s41564-024-01794-8

N/A

0.457DataRank · unranked

20 citations

Jian Miao, Katherine G. Schaefer, C. Russell, Robert J. Pyron, Fuming Zhang +12 more

Structural Study of Aavrh.10 Receptor and Antibody Interactions

Journal of Virology(2021)10.1128/jvi.01249-21

N/A

0.425DataRank · unranked

16 citations

Jennifer C. Yu, Jane Hsi, Paul Chipman, Felix Broecker, Zhang Fuming +6 more

Astrocyte Extracellular Matrix Modulates Neuronal Dendritic Development

Glia(2025)10.1002/glia.70020

N/A

0.407DataRank · unranked

11 citations

Nicholas Margolies, Xiaolu Zhang, Joshua Karpf, Yuefan Song, Natalie Gorham +6 more

Improving impact of heparan sulfate on the endothelial glycocalyx abnormalities in atherosclerosis as revealed by glycan-protein interactome

Carbohydrate Polymers(2024)10.1016/j.carbpol.2024.121834

N/A

0.406DataRank · unranked

14 citations

Xiaohui Xu, Shaoshuai Xie, Anran Sheng, Naihan Han, Zhenyu Tian +8 more

A rolling circle amplification based platform for ultrasensitive detection of heparin

The Analyst(2020)10.1039/d0an02061c

N/A

0.406DataRank · unranked

14 citations

Bingzhi Li, Xiaorui Han, Fuming Zhang, Xing Zhang, Robert J. Linhardt +1 more

N-glycolylated carbohydrates in nature

Glycobiology(2022)10.1093/glycob/cwac048

N/A

0.406DataRank · unranked

14 citations

Chirag Dhar, Peng He, Ajit Varki, Mattheos Koffas, Robert J. Linhardt +1 more

Marine sulfated glycans inhibit the interaction of heparin with S-protein of SARS-CoV-2 Omicron XBB variant

Glycoconjugate Journal(2024)10.1007/s10719-024-10150-1

N/A

0.373DataRank · unranked

11 citations

Yuefan Song, Weihua Jin, Yunran Li, Ke Xia, Seon Beom Kim +9 more

The Sea Cucumber Thyonella gemmata Contains a Low Anticoagulant Sulfated Fucan with High Anti-SARS-CoV-2 Actions against Wild-Type and Delta Variants

Journal of Natural Products(2023)10.1021/acs.jnatprod.3c00151

N/A

0.373DataRank · unranked

11 citations

Marwa Farrag, Poonam Sharma, Deling Shi, Anter A. Shami, Sandeep K. Misra +8 more

Structural characterization of a clinically described heparin-like substance in plasma causing bleeding

Carbohydrate Polymers(2020)10.1016/j.carbpol.2020.116443

N/A

0.330DataRank · unranked

8 citations

Karen Bruzdoski, Vadim Kostousov, Lisa Hensch, Shiu‐Ki Rocky Hui, Fakiha Siddiqui +7 more

Red Algal Sulfated Galactan Binds and Protects Neural Cells from HIV-1 gp120 and Tat

Pharmaceuticals(2021)10.3390/ph14080714

N/A

0.330DataRank · unranked

8 citations

Fakhri Mahdi, Weihua Jin, Fuming Zhang, Robert J. Linhardt, Jason J. Paris +1 more

Interactions of heparin with key glycoproteins of human respiratory syncytial virus

Frontiers in Molecular Biosciences(2023)10.3389/fmolb.2023.1151174

N/A

0.312DataRank · unranked

7 citations

Peng He, Yuefan Song, Robert J. Linhardt, Jonathan S. Dordick, Lianli Chi +2 more

Proline-Rich Region II (PRR2) Plays an Important Role in Tau–Glycan Interaction: An NMR Study

Biomolecules(2022)10.3390/biom12111573

N/A

0.292DataRank · unranked

6 citations

Lufeng Yan, James M. Gibson, Jian Liu, David Eliezer, Guy Lippens +5 more

Small-molecule compound from AlphaScreen disrupts tau-glycan interface

Frontiers in Molecular Biosciences(2022)10.3389/fmolb.2022.1083225

N/A

0.242DataRank · unranked

3 citations

Weihua Jin, James M. Gibson, Anqesha Murray, Nathan Smith, Peng He +4 more

Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin

Glycoconjugate Journal(2024)10.1007/s10719-024-10172-9

N/A

0.241DataRank · unranked

4 citations

Payel Datta, Ke Xia, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao +4 more

Characterization of heparin interactions with Clostridioides difficile toxins and its potential as anti-CDI therapeutics

Carbohydrate Polymers(2024)10.1016/j.carbpol.2024.123143

N/A

0.241DataRank · unranked

4 citations

Shaohui Wang, Jiyuan Yang, Keith Fraser, James M. Gibson, Chunyu Wang +6 more

Marine-Derived Sulfated Glycans Inhibit the Interaction of Heparin with Adhesion Proteins of Mycoplasma pneumoniae

Marine Drugs(2024)10.3390/md22050232

N/A

0.225DataRank · unranked

3 citations

Yuefan Song, Ke Xia, Vitor H. Pomin, Chunyu Wang, Mingqiang Qiao +4 more

Heparan sulfate regulates the fate decisions of human pluripotent stem cells

Stem Cell Reports(2024)10.1016/j.stemcr.2024.11.014

N/A

0.208DataRank · unranked

3 citations

Deena Al Mahbuba, Sayaka Masuko, Qiao Li, Andrew C. Elton, Yefim Zaltsman +8 more

Polysaccharide Sequence Influences the Specificity and Catalytic Activity of Glucuronyl C5-Epimerase

Biochemistry(2020)10.1021/acs.biochem.0c00419

N/A

0.208DataRank · unranked

3 citations

Ke Xia, Yanlei Yu, Robert J. Linhardt, Jonathan S. Dordick, Deepika Vaidyanathan

A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by Candida albicans

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.23.595417

N/A

0.104DataRank · unranked

1 citations

Jian Miao, Katherine G. Schaefer, C. Russell, Robert J. Pyron, Fuming Zhang +12 more

Chemical O-sulfation of N-sulfoheparosan: a route to rare N-sulfo-3-O-sulfoglucosamine and 2-O-sulfoglucuronic acid

Glycoconjugate Journal(2020)10.1007/s10719-020-09939-7

N/A

0.104DataRank · unranked

1 citations

Paul Brodfueher, Li Fu, Fuming Zhang, Shiguo Chen, Jonathan S. Dordick +2 more

Golgi structural defect impairs glycosaminoglycan synthesis, sulfation, and secretion

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.14.464461

N/A

0.104DataRank · unranked

1 citations

Yuefan Song, Ke Xia, Whitney Reid, Jie Li, Sarah Bui +4 more

Rhamnan Sulfate Reduces Atherosclerotic Plaque Formation and Vascular Inflammation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.10.479785

N/A

0.104DataRank · unranked

1 citations

Almudena Gómez‐Hernández, Fuming Zhang, Limary M. Cancel, Xu Feng, Lufeng Yan +12 more

Tandem MS can distinguish hyaluronic acid from N-acetylheparosan

UNC Libraries(2020)10.17615/9rtc-h458

N/A

0.104DataRank · unranked

1 citations

Jian Liu, Zhenqing Zhang, Robert J. Linhardt, Jin Xie

Investigating changes in the gas-phase conformation of Antithrombin III upon binding of Arixtra using traveling wave ion mobility spectrometry (TWIMS)

UNC Libraries(2020)10.17615/khy9-dr09

N/A

0DataRank · unranked

0 citations

Jian Liu, Yongmei Xu, Yuejie Zhao, Robert J. Linhardt, Robert J. Woods +3 more

Structurally Informative Tandem Mass Spectrometry of Highly Sulfated Natural and Chemoenzymatically Synthesized Heparin and Heparan Sulfate Glycosaminoglycans

UNC Libraries(2020)10.17615/8hx1-d578

N/A

0DataRank · unranked

0 citations

Jian Liu, Yongmei Xu, Robert J. Linhardt, I. Jonathan Amster, Muchena J. Kailemia +1 more

Heparan Sulfate Domains Required for Fibroblast Growth Factor 1 and 2 Signaling through Fibroblast Growth Factor Receptor 1c

UNC Libraries(2020)10.17615/r5s4-1h28

N/A

0DataRank · unranked

0 citations

Victor Schultz, Lingyun Li, Robert J. Linhardt, Yongmei Xu, Paul L. DeAngelis +7 more

Preparation and application of a ‘clickable’ acceptor for enzymatic synthesis of heparin oligosaccharides

UNC Libraries(2020)10.17615/8atn-1m43

N/A

0DataRank · unranked

0 citations

Jian Liu, Chao Cai, Robert J. Linhardt, Kristi Edgar

Toward the chemoenzymatic synthesis of heparan sulfate oligosaccharides: oxidative cleavage of p-nitrophenyl group with ceric ammonium salts

UNC Libraries(2020)10.17615/e3mr-ep81

N/A

0DataRank · unranked

0 citations

Chao Cai, Cate Harvey, Robert J. Linhardt, Lingyun Li, Jian Liu

Gas-Phase Analysis of the Complex of Fibroblast GrowthFactor 1 with Heparan Sulfate: A Traveling Wave Ion Mobility Spectrometry (TWIMS) and Molecular Modeling Study

UNC Libraries(2020)10.17615/284a-qz44

N/A

0DataRank · unranked

0 citations

Geert‐Jan Boons, Robert J. Linhardt, Jian Liu, Chengli Zong, I. Jonathan Amster +5 more

Recent advances in sulfotransferase enzyme activity assays

UNC Libraries(2020)10.17615/kxef-h943

N/A

0DataRank · unranked

0 citations

Robert J. Linhardt, Jiraporn Suwan, Priscilla Paul, Jian Liu, Jonathan S. Dordick

Neutralizing the anticoagulant activity of ultra-low-molecular-weight heparins using N -acetylglucosamine 6-sulfatase

UNC Libraries(2020)10.17615/4jmv-qf71

N/A

0DataRank · unranked

0 citations

Lingyun Li, Jian Liu, Xianxuan Zhou, Robert J. Linhardt

Toward an Artificial Golgi: Redesigning the Biological Activities of Heparan Sulfate on a Digital Microfluidic Chip

INDIGO (University of Illinois at Chicago)(2020)10.17615/mqg7-ts67

N/A

0DataRank · unranked

0 citations

Jian Liu, Yongmei Xu, Robert J. Linhardt, Srinivas Akella, Jeffrey G. Martin +2 more

Solution Structures of Chemoenzymatically Synthesized Heparin and Its Precursors

INDIGO (University of Illinois at Chicago)(2020)10.17615/dfhs-5271

N/A

0DataRank · unranked

0 citations

Jesús Jiménez‐Barbero, Robert J. Linhardt, Jin Xie, Lidia Nieto, Zhenqing Zhang +4 more

Chemoenzymatic Design of Heparan Sulfate Oligosaccharides

UNC Libraries(2020)10.17615/4zjq-gr52

N/A

0DataRank · unranked

0 citations

Robert J. Linhardt, Paul L. DeAngelis, Qisheng Zhang, Arlene S. Bridges, Yongmei Xu +5 more

Structural Analysis of the Sulfotransferase (3- O -Sulfotransferase Isoform 3) Involved in the Biosynthesis of an Entry Receptor for Herpes Simplex Virus 1

UNC Libraries(2020)10.17615/fnwt-g812

N/A

0DataRank · unranked

0 citations

Suzanne C. Edavettal, Masahiko Negishi, A.F. Moon, Lars C. Pedersen, Robert J. Linhardt +3 more

Homogeneous low-molecular-weight heparins with reversible anticoagulant activity

UNC Libraries(2020)10.17615/atvp-hv42

N/A

0DataRank · unranked

0 citations

Nigel S. Key, Chao Cai, Po-Hung Hsieh, Robert J. Linhardt, Edward N. Harris +8 more

Heparan Sulfate Facilitates Spike Protein-Mediated SARS-CoV-2 Host Cell Invasion and Contributes to Increased Infection of SARS-CoV-2 G614 Mutant and in Lung Cancer

Frontiers in Molecular Biosciences(2021)10.3389/fmolb.2021.649575

N/A

0DataRank · unranked

57 citations

Weihua Jin, Hyun Mo Yang, John A. Faulkner, Xuehong Song, Hong Qiu +6 more

Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101207

N/A

0DataRank · unranked

48 citations

Priyanka Samanta, Poonam Sharma, Fuming Zhang, Sushil K. Mishra, Pavel Kucheryavy +7 more

Construction of heparan sulfate microarray for investigating the binding of specific saccharide sequences to proteins

Glycobiology(2020)10.1093/glycob/cwaa068

N/A

0DataRank · unranked

28 citations

Guowei Su, Yi Lin, Zhangjie Wang, Yongmei Xu, Vijayakanth Pagadala +6 more

Quantitative analysis of heparan sulfate using isotopically labeled calibrants

Communications Biology(2020)10.1038/s42003-020-01150-6

N/A

0DataRank · unranked

29 citations

Katelyn Arnold, Yongmei Xu, Vijayakanth Pagadala, Guowei Su, Hannah Myatt +3 more

The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus entry into host cells

PLoS Pathogens(2021)10.1371/journal.ppat.1009803

N/A

0DataRank · unranked

31 citations

Mohammad Hasan, John T. Bates, Michael A. Bierdeman, Dallas R. Ederer, Rinkuben C. Parmar +10 more

Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus

Carbohydrate Polymers(2021)10.1016/j.carbpol.2021.117797

N/A

0DataRank · unranked

30 citations

Yuefan Song, Ke Xia, Peng He, Fuming Zhang, Shiguo Chen +10 more

Electrical stimulation of neural-differentiating iPSCs on novel coaxial electroconductive nanofibers

Biomaterials Science(2021)10.1039/d1bm00503k

N/A

0DataRank · unranked

27 citations

Diogo E.S. Nogueira, Carlos A. V. Rodrigues, Flávio Alves Ferreira, Patrizia Paradiso, R. Colaço +6 more

Autophagic degradation of HAS2 in endothelial cells: A novel mechanism to regulate angiogenesis

Matrix Biology(2020)10.1016/j.matbio.2020.02.001

N/A

0DataRank · unranked

32 citations

Maria A. Gubbiotti, Aastha Kapoor, Xiaorui Han, Yanglei Yu, Robert J. Linhardt +2 more

The effect of electrospun scaffolds on the glycosaminoglycan profile of differentiating neural stem cells

Biochimie(2021)10.1016/j.biochi.2021.01.001

N/A

0DataRank · unranked

20 citations

Paiyz E. Mikael, Ke Xia, João C. Silva, Yilan Ouyang, Caitlyn A. Chapman +9 more

Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function

Matrix Biology(2021)10.1016/j.matbio.2021.10.002

N/A

0DataRank · unranked

13 citations

Dallas L. Pineda, Elsa H. Berenstein, Belinda Hauser, Sophie H. Choi, Michaela Prochazkova +9 more

Characterization of Glycosaminoglycan Disaccharide Composition in Astrocyte Primary Cultures and the Cortex of Neonatal Rats

Neurochemical Research(2021)10.1007/s11064-020-03195-9

N/A

0DataRank · unranked

17 citations

Joel G. Hashimoto, Xiaorui Han, Fuming Zhang, Robert J. Linhardt, Marina Guizzetti +1 more

Recent advances on the one-pot synthesis to assemble size-controlled glycans and glycoconjugates and polysaccharides

Carbohydrate Polymers(2021)10.1016/j.carbpol.2021.117672

N/A

0DataRank · unranked

13 citations

Baoxing Shen, Meng Qiao, Robert J. Linhardt, Xing Zhang, Xu Han

Comparative study on the mechanisms of anti-lung cancer activities of three sulfated galactofucans

Food & Function(2021)10.1039/d1fo02062e

N/A

0DataRank · unranked

6 citations

Wanli Wu, Yizhong Bao, Xiaojun Yan, Fuming Zhang, Robert J. Linhardt +3 more

Chemical, enzymatic and biological synthesis of hyaluronic acids

International Journal of Biological Macromolecules(2020)10.1016/j.ijbiomac.2020.02.214

N/A

0DataRank · unranked

78 citations

Meng Qiao, Yuan Ji, Lei Lin, Xing Zhang, Robert J. Linhardt +1 more

Characterization of a Heparan Sulfate Octasaccharide That Binds to Herpes Simplex Virus Type 1 Glycoprotein D

UNC Libraries(2021)10.17615/amcm-k814

N/A

0DataRank · unranked

3 citations

Robert J. Linhardt, R. Marshall Pope, Roselyn J. Eisenberg, Jian Liu, Ram Sasisekharan +7 more

Intrinsically disordered N-terminal domain (NTD) of p53 interacts with mitochondrial PTP regulator Cyclophilin D

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.23.453429

N/A

0DataRank · unranked

2 citations

Xinyue Liu, Alan J. Blayney, Yumeng Zhang, Lauren Gandy, Fuming Zhang +6 more

Golgi structural defect impairs glycosaminoglycan synthesis, sulfation, and secretion

Research Square(2021)10.21203/rs.3.rs-1044799/v1

N/A

0DataRank · unranked

1 citations

Yuefan Song, Ke Xia, Whitney Reid, Jie Li, Sarah Bui +4 more

Crystal Structure and Mutational Analysis of Heparan Sulfate 3- O -Sulfotransferase Isoform 1

UNC Libraries(2021)10.17615/8bv4-dh41

N/A

0DataRank · unranked

0 citations

Masahiko Negishi, Karen A. Lee, Jian Liu, Lars C. Pedersen, Suzanne C. Edavettal +1 more

Loss and rescue of osteocalcin and osteopontin modulate osteogenic and angiogenic features of mesenchymal stem/stromal cells

Journal of Cellular Physiology(2020)10.1002/jcp.29653

N/A

0DataRank · unranked

34 citations

João C. Silva, Christopher M. Hoff, Joaquim M. S. Cabral, Robert J. Linhardt, Cláudia L. da Silva +2 more

Homogalacturonan from squash: Characterization and tau-binding pattern of a sulfated derivative

Carbohydrate Polymers(2022)10.1016/j.carbpol.2022.119250

N/A

0DataRank · unranked

31 citations

Panhang Liu, Chunyu Wang, Fuming Zhang, Robert J. Linhardt, David Eliezer +3 more

Heparan Sulfate Proteoglycans in Tauopathy

Biomolecules(2022)10.3390/biom12121792

N/A

0DataRank · unranked

21 citations

Lauren Gandy, Fuming Zhang, Jian Liu, Chunyu Wang, Laura J. Blair +3 more

Alveolar heparan sulfate shedding impedes recovery from bleomycin-induced lung injury

American Journal of Physiology-Lung Cellular and Molecular Physiology(2020)10.1152/ajplung.00063.2020

N/A

0DataRank · unranked

39 citations

Shujuan Liao, Sarah A. McMurtry, K. Oshima, Xiaorui Han, F. Zhang +8 more

Recent advances in biotechnology for heparin and heparan sulfate analysis

Talanta(2020)10.1016/j.talanta.2020.121270

N/A

0DataRank · unranked

41 citations

Lei Lin, Ke Xia, Jun Li, Xing Zhang, Robert J. Linhardt +1 more

Polyaniline-polycaprolactone fibers for neural applications: Electroconductivity enhanced by pseudo-doping

Materials Science and Engineering C(2020)10.1016/j.msec.2020.111680

N/A

0DataRank · unranked

41 citations

Paiyz E. Mikael, Carlos A. V. Rodrigues, Ranodhi W. Udangawa, Patrizia Paradiso, Caitlyn A. Chapman +7 more

Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants

Frontiers in Molecular Biosciences(2022)10.3389/fmolb.2022.912887

N/A

0DataRank · unranked

30 citations

Fuming Zhang, Seok‐Joon Kwon, John T. Bates, Andrew P. Farmer, Jonathan S. Dordick +3 more

Structural Characteristics of Heparin Binding to SARS-CoV-2 Spike Protein RBD of Omicron Sub-Lineages BA.2.12.1, BA.4 and BA.5

Viruses(2022)10.3390/v14122696

N/A

0DataRank · unranked

23 citations

Changkai Bu, Peng He, Yuefan Song, Jonathan S. Dordick, Robert J. Linhardt +3 more

Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors

Nature Communications(2022)10.1038/s41467-022-34788-3

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0DataRank · unranked

22 citations

Xing Zhang, Ke Xia, Dixy E. Green, Sultan Nacak Baytaş, Yongmei Xu +7 more

Intrinsically Disordered N-terminal Domain (NTD) of p53 Interacts with Mitochondrial PTP Regulator Cyclophilin D

Journal of Molecular Biology(2022)10.1016/j.jmb.2022.167552

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0DataRank · unranked

20 citations

Xinyue Liu, Alan J. Blayney, Yumeng Zhang, Lauren Gandy, Paige Olivia Mirsky +8 more

Expedient Synthesis of a Library of Heparan Sulfate‐Like “Head‐to‐Tail” Linked Multimers for Structure and Activity Relationship Studies**

Angewandte Chemie International Edition(2022)10.1002/anie.202209730

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0DataRank · unranked

20 citations

Li Liang, Weizhun Yang, Sherif Ramadan, Kedar N. Baryal, Chang‐Xin Huo +7 more

Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate

Frontiers in Molecular Biosciences(2022)10.3389/fmolb.2022.1043713

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0DataRank · unranked

18 citations

Ashley J. Canning, Huan Lou, Ke Xia, Peng He, Guowei Su +7 more

Anti-SARS-CoV-2 and anticoagulant properties of Pentacta pygmaea fucosylated chondroitin sulfate depend on high molecular weight structures

Glycobiology(2022)10.1093/glycob/cwac063

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0DataRank · unranked

17 citations

Poonam Sharma, Friederike Eilts, Fuming Zhang, Robert J. Linhardt, Ritesh Tandon +2 more

Fucoidans inhibited tau interaction and cellular uptake

Carbohydrate Polymers(2022)10.1016/j.carbpol.2022.120176

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0DataRank · unranked

17 citations

Chenghui Lu, Yanan Zhu, Jing Zhao, Wenjing Zhang, Lianchun Wang +4 more

Structural Features of Heparin and Its Interactions With Cellular Prion Protein Measured by Surface Plasmon Resonance

Frontiers in Molecular Biosciences(2020)10.3389/fmolb.2020.594497

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0DataRank · unranked

10 citations

Fuming Zhang, David A. Harris, Robert J. Linhardt, So Young Kim

Interactions of marine sulfated glycans with antithrombin and platelet factor 4

Frontiers in Molecular Biosciences(2022)10.3389/fmolb.2022.954752

N/A

0DataRank · unranked

11 citations

Weihua Jin, Vitor H. Pomin, Fuming Zhang, Robert J. Linhardt, Wenjing Zhang

Interactions of fibroblast growth factors with sulfated galactofucan from Saccharina japonica

International Journal of Biological Macromolecules(2020)10.1016/j.ijbiomac.2020.05.183

N/A

0DataRank · unranked

12 citations

Di Jiang, Wenjing Zhang, Chunyu Wang, Ke Xia, Fuming Zhang +2 more

Effect of high glucose on glycosaminoglycans in cultured retinal endothelial cells and rat retina

Glycobiology(2022)10.1093/glycob/cwac029

N/A

0DataRank · unranked

16 citations

Yuefan Song, Ke Xia, Kevin McCarthy, Fuming Zhang, Robert J. Linhardt +2 more

Sex differences in hippocampal structural plasticity and glycosaminoglycan disaccharide levels after neonatal handling

Experimental Neurology(2022)10.1016/j.expneurol.2022.114313

N/A

0DataRank · unranked

10 citations

Mo L. Singer, Calla M. Goeke, Fuming Zhang, Yuefan Song, Ke Xia +3 more

Ionically Complexed Nanoparticles for Heparin Oral Delivery

Precision Nanomedicine(2022)10.33218/001c.37505

N/A

0DataRank · unranked

3 citations

Nicole Leonick, Varenya Gade, David Frey, Fuming Zhang, Robert J. Linhardt +2 more

Expedient Synthesis of a Library of Heparan Sulfate Like “Head to Tail” Linked Multimers for Structure and Activity Relationship Studies

ChemRxiv(2022)10.26434/chemrxiv-2022-m03tb

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0DataRank · unranked

1 citations

Li Liang, Weizhun Yang, Sherif Ramadan, Kedar N. Baryal, Chang‐Xin Huo +7 more

The Loss of Endothelial Glycocalyx in Diabetic Retinopathy

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3558

N/A

0DataRank · unranked

0 citations

Yuefan Song, Ke Xia, Diana Cruz‐Topete, Kevin McCarthy, Fuming Zhang +3 more

Ionically Complexed Nanoparticles for Heparin Oral Delivery

Research Square(2022)10.21203/rs.3.rs-1631202/v1

N/A

0DataRank · unranked

0 citations

Nicole Leonick, Verenya Gade, David Frey, Fuming Zhang, Robert J. Linhardt +2 more

Expedient Synthesis of a Library of Heparan Sulfate Like “Head to Tail” Linked Multimers for Structure and Activity Relationship Studies

ChemRxiv(2022)10.26434/chemrxiv-2022-m03tb-v2

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0DataRank · unranked

0 citations

Li Liang, Weizhun Yang, Sherif Ramadan, Kedar N. Baryal, Chang‐Xin Huo +7 more

Heparan Sulfate Proteoglycans in Tauopathy

UNC Libraries(2022)10.17615/2akk-x235

N/A

0DataRank · unranked

0 citations

Lauren Gandy, Robert J. Linhardt, Laura J. Blair, Jian Liu, Fuming Zhang +3 more

Regional and disease-specific glycosaminoglycan composition and function in decellularized human lung extracellular matrix

Acta Biomaterialia(2023)10.1016/j.actbio.2023.06.043

N/A

0DataRank · unranked

20 citations

Yuefan Song, Fuming Zhang, Loredana Asarian, Isaac Downs, Brad de Young +6 more

Using heparan sulfate octadecasaccharide (18-mer) as a multi-target agent to protect against sepsis

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2209528120

N/A

0DataRank · unranked

25 citations

Yongmei Xu, Katelyn Arnold, Fuming Zhang, Jine Li, Rani S. Sellers +8 more

Bioengineered production of glycosaminoglycans and their analogues

Systems Microbiology and Biomanufacturing(2020)10.1007/s43393-020-00011-x

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0DataRank · unranked

11 citations

Fuming Zhang, Robert J. Linhardt, Weihua Jin

A Revised Structure for the Glycolipid Terminus of Escherichia coli K5 Heparosan Capsular Polysaccharide

Biomolecules(2020)10.3390/biom10111516

N/A

0DataRank · unranked

17 citations

Li Fu, Ke Xia, Shiguo Chen, Fuming Zhang, Jonathan S. Dordick +2 more

Antimicrobial effects of positively charged, conductive electrospun polymer fibers

Materials Science and Engineering C(2020)10.1016/j.msec.2020.111247

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0DataRank · unranked

17 citations

Domyoung Kim, Sneha Gopal, Aaron Tice, Kening Lang, Jonathan S. Dordick +3 more

Characterization of squash polysaccharide and the anti-diabetic effect on type 2 diabetic rat revealed by urine metabolomics analysis

Food Science and Human Wellness(2023)10.26599/fshw.2022.9250237

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0DataRank · unranked

5 citations

Fuming Zhang, Quanhong Li, Baoguo Sun, Yuyu Zhang, Robert J. Linhardt +1 more

Apolipoprotein E Recognizes Alzheimer's Disease Associated 3‐O Sulfation of Heparan Sulfate

Angewandte Chemie(2023)10.1002/ange.202212636

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0DataRank · unranked

3 citations

Yanan Zhu, Guowei Su, Jing Zhao, Ashely Canning, James M. Gibson +9 more

Synthesis of multivalent sialyllactose-conjugated PAMAM dendrimers: Binding to SARS-CoV-2 spike protein and influenza hemagglutinin

International Journal of Biological Macromolecules(2023)10.1016/j.ijbiomac.2023.125714

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0DataRank · unranked

3 citations

Ke Xia, Yuefan Song, Ritesh Tandon, Rudra Channappanavar, Fuming Zhang +2 more

Marine Sulfated Glycans Inhibit the Interaction of Glycosaminoglycans with SARS-CoV-2 Omicron XBB Variant S-Protein

Preprints.org(2023)10.20944/preprints202305.1749.v1

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0DataRank · unranked

1 citations

Yuefan Song, Weihua Jin, Yunran Li, Ke Xia, Seon Beom Kim +8 more

Synthesis of selected unnatural sugar nucleotides for biotechnological applications

Critical Reviews in Biotechnology(2020)10.1080/07388551.2020.1844623

N/A

0DataRank · unranked

18 citations

Bingzhi Li, Yuan Ji, Lei Lin, Robert J. Linhardt, Xing Zhang +1 more

Analysis of the Glycosaminoglycan Chains of Proteoglycans

Journal of Histochemistry & Cytochemistry(2020)10.1369/0022155420937154

N/A

0DataRank · unranked

62 citations

Fuming Zhang, Robert J. Linhardt, Yuefan Song

Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin

Viruses(2024)10.3390/v16020237

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0DataRank · unranked

10 citations

Yuefan Song, Weihua Jin, Ke Xia, Grace C. Burnett, Wanjin Qiao +8 more

Astrocyte extracellular matrix modulates neuronal dendritic development

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.06.606424

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0DataRank · unranked

1 citations

Nicholas Margolies, Xiaolu Zhang, Joshua Karpf, Yuefan Song, Brett A. Davis +5 more

Extracellular matrix decorated polycaprolactone scaffolds for improved mesenchymal stem/stromal cell osteogenesis towards a patient‐tailored bone tissue engineering approach

Journal of Biomedical Materials Research Part B Applied Biomaterials(2020)10.1002/jbm.b.34554

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0DataRank · unranked

66 citations

Marta S. Carvalho, Ranodhi N. Udangawa, Carla Moura, Joaquim M. S. Cabral, Cláudia L. da Silva +4 more

Characterization of Heparin Interactions With Recombinant Rodent Stabilin‐2/Hyaluronic Acid Receptor for Endocytosis (HARE)

Proteoglycan Research(2025)10.1002/pgr2.70027

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0DataRank · unranked

0 citations

Evan A. Schroder, Joseph D. Staab, William P. Singh, Callan J. Schroder, Grant Hatcher +11 more

Chronic Ethanol Drinking Alters Medial Prefrontal Cortex and Nucleus Accumbens Astrocyte Translatome and Extracellular Matrix Glycosaminoglycans

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.30.679577

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0DataRank · unranked

0 citations

Angela R. Ozburn, Cheryl Reed, Jason Erk, Yuefan Song, Jiyuan Yang +9 more

Expression of enzymes for 3′-phosphoadenosine-5′-phosphosulfate (PAPS) biosynthesis and their preparation for PAPS synthesis and regeneration

Applied Microbiology and Biotechnology(2020)10.1007/s00253-020-10709-6

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0DataRank · unranked

38 citations

Li Fu, Wenqin He, Mattheos Koffas, Jonathan S. Dordick, Robert J. Linhardt +1 more

Glycocalyx‐Like Hydrogel Coatings for Small Diameter Vascular Grafts

Advanced Functional Materials(2020)10.1002/adfm.201908963

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0DataRank · unranked

73 citations

Juan Wang, Tylee Lin, Amanda Weyers, Hualong Bai, Lingfeng Qin +16 more

The structure-activity relationship of the interactions of SARS-CoV-2 spike glycoproteins with glucuronomannan and sulfated galactofucan from Saccharina japonica

International Journal of Biological Macromolecules(2020)10.1016/j.ijbiomac.2020.09.184

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0DataRank · unranked

78 citations

Wenjing Zhang, Dipanwita Mitra, Martin G. McCandless, Poonam Sharma, Ritesh Tandon +3 more

Glycosaminoglycan remodeling during chondrogenic differentiation of human bone marrow−/synovial-derived mesenchymal stem/stromal cells under normoxia and hypoxia

Glycoconjugate Journal(2020)10.1007/s10719-020-09911-5

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0DataRank · unranked

25 citations

Xiaorui Han, Teresa P. Silva, Ke Xia, Paiyz E. Mikael, Joaquim M. S. Cabral +3 more

Structural analysis of a glucoglucuronan derived from laminarin and the mechanisms of its anti-lung cancer activity

International Journal of Biological Macromolecules(2020)10.1016/j.ijbiomac.2020.07.069

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0DataRank · unranked

27 citations

Xinyue He, Wanli Wu, Yizhong Bao, Sanying Wang, Min Cai +7 more

Heparosan Chain Characterization: Sequential Depolymerization of E. Coli K5 Heparosan by a Bacterial Eliminase Heparin Lyase III and a Bacterial Hydrolase Heparanase Bp to Prepare Defined Oligomers

Biotechnology Journal(2020)10.1002/biot.202000336

N/A

0DataRank · unranked

7 citations

Lufeng Yan, Adeola E. Awofiranye, Jonathan S. Dordick, Robert J. Linhardt, Payel Datta

FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling

BMC Biology(2020)10.1186/s12915-020-00813-4

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0DataRank · unranked

28 citations

Ye Tian, Lu Han, Chao Liu, Tian‐Yu Sun, Ling Li +13 more

Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: Paving the way to a diverse library for glycobiologists

UNC Libraries(2020)10.17615/hmkb-t953

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0DataRank · unranked

2 citations

Jian Liu, Robert J. Linhardt

2- O -Sulfated Domains in Syndecan-1 Heparan Sulfate Inhibit Neutrophil Cathelicidin and Promote Staphylococcus aureus Corneal Infection

UNC Libraries(2020)10.17615/re70-e673

N/A

0DataRank · unranked

1 citations

Atsuko Hayashida, Shiro Amano, Richard L. Gallo, Jian Liu, Pyong Woo Park +1 more

N-glycolyl chondroitin synthesis using metabolically engineered E. coli

Research Square(2020)10.21203/rs.3.rs-35611/v2

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0DataRank · unranked

0 citations

Sultan Nacak Baytaş, Ke Xia, Abinaya Badri, Wenqin He, Ajit Varki +3 more

N-glycolyl chondroitin synthesis using metabolically engineered E. coli

Research Square(2020)10.21203/rs.3.rs-35611/v1

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0DataRank · unranked

0 citations

Sultan Nacak Baytaş, Ke Xia, Abinaya Badri, Wenqin He, Ajit Varki +3 more

Chemoenzymatic Synthesis of Uridine Diphosphate-GlcNAc and Uridine Diphosphate-GalNAc Analogs for the Preparation of Unnatural Glycosaminoglycans

Figshare(2020)10.17615/mf6n-0750

N/A

0DataRank · unranked

0 citations

Michel Weïwer, Sayaka Masuko, Dixy E. Green, Paul L. DeAngelis, Jian Liu +2 more

Synthesis of Uridine 5′-diphosphoiduronic Acid: A Potential Substrate for the Chemoenzymatic Synthesis of Heparin

Figshare(2020)10.17615/3qr2-8b67

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0DataRank · unranked

0 citations

Dixy E. Green, Miao Chen, Michel Weïwer, Robert J. Linhardt, Paul L. DeAngelis +2 more

Structural Analysis of Heparin-Derived 3- O -Sulfated Tetrasaccharides: Antithrombin Binding Site Variants

UNC Libraries(2020)10.17615/qng2-5e70

N/A

0DataRank · unranked

0 citations

Lei Lin, Jian Liu, I. Jonathan Amster, Fuming Zhang, Xing Zhang +5 more

Enzymatic Redesigning of Biologically Active Heparan Sulfate

UNC Libraries(2020)10.17615/c0yj-rz66

N/A

0DataRank · unranked

0 citations

Lars C. Pedersen, Lynda M. McDowell, Jinghua Chen, Eva Muñoz, Robert J. Linhardt +4 more

Affinity, Kinetic, and Structural Study of the Interaction of 3- O -Sulfotransferase Isoform 1 with Heparan Sulfate †

UNC Libraries(2020)10.17615/0g7e-3x67

N/A

0DataRank · unranked

0 citations

Jian Liu, Robert J. Linhardt, Ding Xu, Melissa L. Kemp, Eva Muñoz +1 more

Recent progress and applications in glycosaminoglycan and heparin research

UNC Libraries(2020)10.17615/peb0-qg62

N/A

0DataRank · unranked

0 citations

Fuming Zhang, Robert J. Linhardt, Tatiana N. Laremore, Jian Liu, Jonathan S. Dordick