Patrick J. Lao

Columbia University Irving Medical Center

Also affiliated with Columbia University

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.283Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Longitudinal changes in white matter hyperintensity volume accelerate across the Alzheimer's continuum in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70679

Top 57%

0.283DataRank

Top 57%5 citations

Natalie Edwards, Lisi Flores Aguilar, Mohamad J. Alshikho, Anna Smith, Rachel LeMay +13 more

Papers

Driven by 34 papers — median percentile 22. Top paper: “Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study”.

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2022)10.1016/s1474-4422(22)00408-2

N/A

1.1DataRank · unranked

56 citations

Brian A. Gordon, Julie K. Wisch, Shaney Flores, Rachel L. Henson, Omar H. Butt +95 more

Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex

Nature Neuroscience(2025)10.1038/s41593-025-02000-6

N/A

0.736DataRank · unranked

42 citations

Emma M. Coomans, Liana G. Apostolova, Suzanne L. Baker, Henryk Barthel, Thomas G. Beach +92 more

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00084-x

N/A

0.542DataRank · unranked

36 citations

Nicole S. McKay, Anna H. Boerwinkle, James L. Kennedy, Shaney Flores, Benjamin L. Handen +86 more

Cerebrovascular disease is associated with Alzheimer’s plasma biomarker concentrations in adults with Down syndrome

Brain Communications(2024)10.1093/braincomms/fcae331

N/A

0.510DataRank · unranked

29 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +70 more

Obstructive sleep apnea, cerebrovascular disease, and amyloid in older adults with Down syndrome across the Alzheimer’s continuum

SLEEP Advances(2022)10.1093/sleepadvances/zpac013

N/A

0.457DataRank · unranked

20 citations

Molly E. Zimmerman, Sigan L. Hartley, José Gutierrez, David B. Keator, Kay C. Igwe +16 more

The striatum is an early, accurate indicator of amyloid burden using [ 11 C]PiB in Down syndrome: Comparison of two radiotracers

Alzheimer s & Dementia(2025)10.1002/alz.70141

N/A

0.385DataRank · unranked

12 citations

Brecca Bettcher, Andrew K McVea, Alexandra H DiFilippo, Matthew Zammit, Lisette LeMerise +21 more

Depressive Symptoms Correlate With Tau Accumulation Rates in Amyloid Positive Adults

American Journal of Geriatric Psychiatry(2025)10.1016/j.jagp.2025.04.207

N/A

0.360DataRank · unranked

10 citations

Aubrey S. Johnson, Patrick J. Brown, Frank A. Provenzano, Patrick J. Lao, Karen Marder +2 more

Longitudinal changes in white matter hyperintensity volume accelerate across the Alzheimer's continuum in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70679

Top 57%

0.283DataRank

Top 57%5 citations

Natalie Edwards, Lisi Flores Aguilar, Mohamad J. Alshikho, Anna Smith, Rachel LeMay +13 more

Interactions among neighborhood conditions, sleep quality, and episodic memory across the adult lifespan

Ethnicity and Health(2024)10.1080/13557858.2024.2379116

N/A

0.241DataRank · unranked

4 citations

Patrick J. Lao, Justina Avila‐Rieger, Indira C. Turney, Paris B. Adkins‐Jackson, Dayna A. Johnson +8 more

Alzheimer's disease diagnostic progression is associated with cerebrovascular disease and neuroinflammation in adults with Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70726

N/A

0.241DataRank · unranked

4 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +20 more

The relationship between racial discrimination and white matter among Black older adults

Neurobiology of Aging(2025)10.1016/j.neurobiolaging.2025.07.017

N/A

0.165DataRank · unranked

2 citations

Ji Hyun Lee, Emily P. Morris, Ketlyne Sol, Monica Nelson, Kiana A. Scambray +7 more

The tau biomarker cascade is condensed in Down syndrome compared with sporadic Alzheimer’s disease

Brain(2025)10.1093/brain/awaf428

N/A

0.165DataRank · unranked

2 citations

Hailey Bruzzone, Karly Alex Cody, Jacob Morse, Rachael E. Wilson, Brecca Bettcher +65 more

Resistance and resilience to Alzheimer's disease in Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70151

N/A

0DataRank · unranked

13 citations

Elouise A. Koops, Beau M. Ances, Elizabeth J. Andrews, Eider M. Arenaza‐Urquijo, Alexandre Bejanin +40 more

Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer’s disease and related neurodegenerative pathologies using 7T postmortem MRI

Journal of Neuropathology & Experimental Neurology(2025)10.1093/jnen/nlaf010

N/A

0DataRank · unranked

6 citations

Jinghang Li, Jacob Berardinelli, Hecheng Jin, Tales Santini, Jaehoon Noh +69 more

PET‐measured amyloid beta accumulates at an accelerated rate in Down syndrome compared to neurotypical populations

Alzheimer s & Dementia(2025)10.1002/alz.70357

N/A

0DataRank · unranked

4 citations

Alexandra H DiFilippo, Max McLachlan, Brecca Betcher, Matthew Zammit, Tobey J. Betthauser +20 more

Age and sex are associated with Alzheimer's disease neuropathology in Down syndrome

Alzheimer s & Dementia(2025)10.1002/alz.70408

N/A

0DataRank · unranked

4 citations

Phong Ngo, Jesse R. Pascual, Freddy Gonzalez, Michael Phelan, Sierra Wright +9 more

Phase contrast-derived cerebral blood flow is associated with neurodegeneration and cerebrovascular injury in older adults

Frontiers in Neuroscience(2025)10.3389/fnins.2025.1538956

N/A

0DataRank · unranked

3 citations

Clarissa Morales, A. Zarina Kraal, Mohamad J. Alshikho, Patrick J. Lao, Indira C. Turney +8 more

A comparison of multiple amyloid PET radiotracers for Down syndrome clinical trials

Brain Communications(2025)10.1093/braincomms/fcaf406

N/A

0DataRank · unranked

2 citations

Julie C. Price, Bradley T. Christian, Michael S. Rafii, Beau M. Ances, Howard Andrews +51 more

Genetically determined Alzheimer's disease research advances: The Down Syndrome & Autosomal Dominant Alzheimer's Disease 2024 Conference

Alzheimer s & Dementia(2025)10.1002/alz.70309

N/A

0DataRank · unranked

4 citations

Lucía Maure-Blesa, Beau M. Ances, Lisi Flores Aguilar, Sigan L. Hartley, Jason Hassenstab +54 more

Preliminary investigation of obstructive sleep apnea and Alzheimer’s disease in down syndrome

SLEEP Advances(2025)10.1093/sleepadvances/zpaf044

N/A

0DataRank · unranked

1 citations

David T. Plante, Victoria Fleming, Benjamin L. Handen, Patrick J. Lao, Jamie C. Peven +8 more

The Consortium for Clarity in ADRD Research Through Imaging (CLARiTI): Overview of consortium sites and anticipated enrollment

Alzheimer s & Dementia(2025)10.1002/alz.70880

Top 100%

0DataRank

Top 100%0 citations

Sarah Biber, Marilyn Albert, Michael L. Alosco, Konstantinos Arfanakis, Tammie L.S. Benzinger +57 more

White matter microstructure associations to amyloid burden in adults with Down syndrome

NeuroImage Clinical(2021)10.1016/j.nicl.2021.102908

N/A

0DataRank · unranked

6 citations

Matthew Zammit, Minjie Wu, Patrick J. Lao, Douglas Dean, Sterling C. Johnson +12 more

Blood‐brain barrier integrity and vessel morphology in adults with Down syndrome and Alzheimer's neuropathology

Alzheimer s & Dementia(2025)10.1002/alz70855_106199

N/A

0DataRank · unranked

0 citations

Jesse R. Pascual, Halyma Nguyen, Annie Du, Natalie C. Edwards, Patrick J. Lao +9 more

Probing the proteome to explore potential correlates of increased Alzheimer's‐related cerebrovascular disease in adults with Down syndrome

Alzheimer s & Dementia(2022)10.1002/alz.12627

N/A

0DataRank · unranked

12 citations

Melissa Petersen, Fan Zhang, Patrick J. Lao, Molly E. Zimmerman, Yian Gu +19 more

Longitudinal decline in semantic versus letter fluency, but not their ratio, marks incident Alzheimer’s disease in Latinx Spanish-speaking older individuals

Journal of the International Neuropsychological Society(2023)10.1017/s1355617722000856

N/A

0DataRank · unranked

4 citations

Anton J. Kociolek, Patrick J. Lao, Yaakov Stern, Jennifer J. Manly, Jet M. J. Vonk +1 more

Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndrome

medRxiv(2023)10.1101/2023.11.28.23298693

N/A

0DataRank · unranked

10 citations

Patrick J. Lao, Mohamad J. Alshikho, Olivia M. Ericsson, Batool Rizvi, Melissa Petersen +20 more

Pathways linking pulse pressure to dementia in adults with Down syndrome

medRxiv(2023)10.1101/2023.10.26.23297625

N/A

0DataRank · unranked

0 citations

Patrick J. Lao, Mithra Sathishkumar, Lisa Taylor, Nazek Queder, Liv McMillan +17 more

Microglia measured by TSPO PET are associated with Alzheimer's disease pathology and mediate key steps in a disease progression model

Alzheimer s & Dementia(2024)10.1002/alz.13699

N/A

0DataRank · unranked

44 citations

Aubrey S. Johnson, Anna Smith, Galen Ziaggi, Andrew E. Roetman, Diana Guzman +9 more

Cerebrovascular disease emerges with age and Alzheimer’s disease in adults with Down syndrome

Scientific Reports(2024)10.1038/s41598-024-61962-y

N/A

0DataRank · unranked

28 citations

Natalie Edwards, Lisi Flores Aguilar, Mohamad J. Alshikho, Batool Rizvi, Dana Tudorascu +11 more

Small vessel cerebrovascular disease is associated with cognition in prospective Alzheimer’s clinical trial participants

Alzheimer s Research & Therapy(2024)10.1186/s13195-024-01395-x

N/A

0DataRank · unranked

12 citations

Dejania Cotton‐Samuel, Patrick J. Lao, Julia F. Chang, Jeffrey D. Pyne, Mohamad J. Alshikho +9 more

A pathway linking pulse pressure to dementia in adults with Down syndrome

Brain Communications(2024)10.1093/braincomms/fcae157

N/A

0DataRank · unranked

3 citations

Patrick J. Lao, Mithra Sathishkumar, Lisa Taylor, Nazek Queder, Liv McMillan +17 more

Psychotic symptoms are associated with elevated tau PET signal in the amygdala independent of Alzheimer’s disease clinical severity and amyloid burden

medRxiv(2024)10.1101/2024.01.12.24301221

N/A

0DataRank · unranked

2 citations

Galen Ziaggi, Anna C. Smith, Hannah M. Houlihan, Lauren Heuer, Diana S. Guzmán +8 more

Increased fibrin deposition in the brains of individuals with Down syndrome and Alzheimer’s disease

Alzheimer s & Dementia(2024)10.1002/alz.089882

N/A

0DataRank · unranked

0 citations

Lisi Flores Aguilar, Natalie C. Edwards, Patrick J. Lao, Jae Kyu Ryu, Katerina Akassoglou +7 more

Regional differences in astrocytic Aquaporin-4 protein levels and distribution in aging and Alzheimer's disease in down syndrome

Neurobiology of Disease(2025)10.1016/j.nbd.2025.107114

N/A

0DataRank · unranked

7 citations

Haley Miyasato, Kevin Camey, Krina A Ghadia, Elizabeth J. Andrews, Phong Ngo +17 more

Patrick J. Lao

Indexed papers

Top data-sharing exemplar

Papers