D. Borden Lacy

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 29 papers. Top paper: “Structural elucidation of the Clostridioides difficile transferase toxin reveals a single-site binding mode for the enzyme”.

Structural elucidation of the Clostridioides difficile transferase toxin reveals a single-site binding mode for the enzyme

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1920555117

N/A

0.896DataRank · unranked

27 citations

David M. Anderson, Audrey K. Thomas, D. Borden Lacy, Michael J. Sheedlo

The Helicobacter pylori Cag Type IV Secretion System

Trends in Microbiology(2020)10.1016/j.tim.2020.02.004

N/A

0.749DataRank · unranked

146 citations

D. Borden Lacy, Melanie D. Ohi, Timothy L. Cover

Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex

eLife(2020)10.7554/elife.59495

N/A

0.617DataRank · unranked

60 citations

Jeong Min Chung, Neha Sawhney, Clarissa L. Durie, Timothy L. Cover, Melanie D. Ohi +2 more

Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection

PLoS Pathogens(2022)10.1371/journal.ppat.1010323

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0.515DataRank · unranked

30 citations

John A. Shupe, Rory Cave, Kevin O. Childress, M. Kay Washington, Sarah A. Kuehne +2 more

Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection

PLoS Pathogens(2024)10.1371/journal.ppat.1012568

N/A

0.446DataRank · unranked

11 citations

Shannon L. Kordus, John A. Shupe, Rubén Cano Rodríguez, Anna Smith, Julia K. Bohannon +3 more

Strain Variation in Clostridioides difficile Cytotoxicity Associated with Genomic Variation at Both Pathogenic and Nonpathogenic Loci

mSphere(2022)10.1128/msphere.00174-22

N/A

0.373DataRank · unranked

11 citations

Ali Pirani, D. Borden Lacy, Philip C. Hanna, Evan S. Snitkin, Katie Saund

Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB

mBio(2023)10.1128/mbio.01857-23

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0.360DataRank · unranked

10 citations

Caroline S. Cencer, Matthew J. Tyska, D. Borden Lacy, Kevin O. Childress

Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS

eLife(2021)10.7554/elife.70427

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0DataRank · unranked

41 citations

Clarissa L. Durie, Jeong Min Chung, Louise Chang, Jacquelyn Roberts, Michele S. Swanson +3 more

Clostridioides difficile infection induces a rapid influx of bile acids into the gut during colonization of the host

Cell Reports(2021)10.1016/j.celrep.2021.109683

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0DataRank · unranked

33 citations

Emma R. Guiberson, William N. Beavers, John A. Shupe, M. Kay Washington, D. Borden Lacy +4 more

Functional Properties of Oligomeric and Monomeric Forms of Helicobacter pylori VacA Toxin

Infection and Immunity(2021)10.1128/iai.00348-21

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0DataRank · unranked

16 citations

Mark S. McClain, Amanda L. Erwin, Mandy D. Truelock, Anne M. Campbell, Catherine S. Leasure +6 more

Strain variation in Clostridioides difficile toxin activity associated with genomic variation at both PaLoc and non-PaLoc loci

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.08.471880

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0DataRank · unranked

4 citations

Ali Pirani, D. Borden Lacy, Philip C. Hanna, Evan S. Snitkin, Katie Saund

Cryo-EM reveals new species-specific proteins and symmetry elements in the Legionella pneumophila Dot/Icm T4SS

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.18.449039

N/A

0DataRank · unranked

1 citations

Clarissa L. Durie, Jeong Min Chung, Louise Chang, Michele S. Swanson, D. Borden Lacy +2 more

Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.22.460915

N/A

0DataRank · unranked

0 citations

John A. Shupe, Rory J. Cave, M. Kay Washington, Sarah A. Kuehne, D. Borden Lacy +1 more

Molecular architecture of bacterial type IV secretion systems

PLoS Pathogens(2022)10.1371/journal.ppat.1010720

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0DataRank · unranked

68 citations

Melanie D. Ohi, D. Borden Lacy, Timothy L. Cover, Michael J. Sheedlo

Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex

eLife(2020)10.7554/elife.59530

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0DataRank · unranked

76 citations

Michael J. Sheedlo, Jeong Min Chung, Brenda Byrne, Min Su, Thomas J. Knight +4 more

Paeniclostridium sordellii uterine infection is dependent on the estrous cycle

PLoS Pathogens(2022)10.1371/journal.ppat.1010997

N/A

0DataRank · unranked

6 citations

M. Kay Washington, D. Borden Lacy, Sarah C. Bernard

Toxin-mediated downregulation of absorptive ion transporters NHE3, DRA, and SGLT1 in the colon contributes to diarrhea associated with Clostridioides difficile infection

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.12.516162

N/A

0DataRank · unranked

0 citations

Izumi Kaji, Anna Smith, Lauren Walker, John A. Shupe, Pradeep K. Dudeja +3 more

Increased intestinal permeability and downregulation of absorptive ion transporters Nhe3 , Dra , and Sglt1 contribute to diarrhea during Clostridioides difficile infection

Gut Microbes(2023)10.1080/19490976.2023.2225841

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0DataRank · unranked

26 citations

Izumi Kaji, Anna Smith, Lauren Walker, John A. Shupe, M. Kay Washington +5 more

Nonsteroidal anti-inflammatory drugs sensitize epithelial cells to Clostridioides difficile toxin–mediated mitochondrial damage

Science Advances(2023)10.1126/sciadv.adh5552

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0DataRank · unranked

14 citations

Nile U. Bayard, Jessica L. Hart, Audrey K. Thomas, Emma E. Furth, D. Borden Lacy +3 more

Nanobodies against C. difficile TcdA and TcdB reveal unexpected neutralizing epitopes and provide a toolkit for toxin quantitation in vivo

PLoS Pathogens(2023)10.1371/journal.ppat.1011496

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0DataRank · unranked

20 citations

Heather K. Kroh, Rubén Cano Rodríguez, Rebecca A. Shrem, F. Christopher Peritore‐Galve, John A. Shupe +4 more

Cecum axis (CecAx) preservation reveals physiological and pathological gradients in mouse gastrointestinal epithelium

Gut Microbes(2023)10.1080/19490976.2023.2185029

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0DataRank · unranked

6 citations

Nicolas G. Shealy, Michelle L. Reyzer, John A. Shupe, Emily H. Green, Uswah Siddiqi +4 more

Paeniclostridium sordellii NanS works synergistically with TcsL to increase cytotoxicity and the severity of pathogenesis in the murine uterus

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.22.546043

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0DataRank · unranked

0 citations

Heather K. Kroh, M. Kay Washington, D. Borden Lacy, Sarah C. Bernard

Species-specific components of the Helicobacter pylori Cag type IV secretion system

Infection and Immunity(2025)10.1128/iai.00493-24

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0DataRank · unranked

6 citations

Arwen E. Frick-Cheng, Lauren E. Solecki, Heather K. Kroh, W. Hayes McDonald, D. Borden Lacy +4 more

Clostridioides difficile toxin A and toxin B inhibit toxin-specific adaptive immune responses through glucosyltransferase-dependent activity

Mucosal Immunology(2025)10.1016/j.mucimm.2025.08.004

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0DataRank · unranked

4 citations

Jennifer Londregan, Joshua E. Denny, Ellie N Hulit, Nontokozo V. Mdluli, F. Christopher Peritore‐Galve +6 more

A targeted cell lysis mechanism facilitates toxin release in Clostridioides difficile

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.22.677799

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0DataRank · unranked

2 citations

Kateryna Nabukhotna, Rubén Cano Rodríguez, Evan Krystofiak, Kevin O. Childress, Anna J. Smith +7 more

Murine intrarectal instillation of purified recombinant C. difficile toxins enables mechanistic studies of pathogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.30.274738

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0DataRank · unranked

0 citations

Sarah C. Bloch, John A. Shupe, Erin N. Laubacher, M. Kay Washington, Robert J. Coffey +2 more

Clostridioides difficile toxin B inhibits antigen-specific adaptive immune responses through glucosyltransferase-dependent activity 3906

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1653

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0DataRank · unranked

0 citations

Jennifer Londregan, Joshua E. Denny, F. Christopher Peritore, Mohamad‐Gabriel Alameh, Joseph P. Zackular +3 more

Structural analysis of the Legionella pneumophila Dot/Icm Type IV Secretion System Core Complex

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.28.271460

N/A

0DataRank · unranked

0 citations

Michael J. Sheedlo, Jeong Min Chung, Brenda Byrne, Min Su, Thomas J. Knight +4 more

Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.01.277012

N/A

0DataRank · unranked

0 citations

Jeong Min Chung, Neha Sawhney, Clarissa L. Durie, Timothy L. Cover, Melanie D. Ohi +2 more