Brian S. Appleby

Also affiliated with University Hospitals Cleveland Medical Center, University School, Case Western Reserve University

Biochemistry, Genetics and Molecular BiologyMedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

4.1Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium

Alzheimer s & Dementia(2020)10.1002/alz.12033

Top 8%

2.6DataRank

Top 8%169 citations

Danielle Brushaber, Jeremy A. Syrjanen, Walter K. Kremers, Julie A. Fields, Leah K. Forsberg +80 more

Papers

Driven by 48 papers — median percentile 53. Top paper: “Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium”.

Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium

Alzheimer s & Dementia(2020)10.1002/alz.12033

Top 8%

2.6DataRank

Top 8%169 citations

Danielle Brushaber, Jeremy A. Syrjanen, Walter K. Kremers, Julie A. Fields, Leah K. Forsberg +80 more

Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration

Neurology(2021)10.1212/wnl.0000000000011848

N/A

1.7DataRank · unranked

108 citations

Ping Wang, Adam M. Staffaroni, Carolin Heller, Yann Cobigo, Amy Wolf +88 more

Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort

Alzheimer s & Dementia(2020)10.1002/alz.12046

Top 16%

1.3DataRank

Top 16%45 citations

P. Wang, Katya Rascovsky, Alon Wolf, Brian S. Appleby, Jessica Bove +73 more

Proposed research criteria for prodromal behavioural variant frontotemporal dementia

Brain(2021)10.1093/brain/awab365

N/A

0.698DataRank · unranked

104 citations

Reena Gottesman, Masood Manoochehri, Silvia Chapman, Brian S. Appleby, Danielle Brushaber +37 more

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders

Cell Reports Medicine(2022)10.1016/j.xcrm.2022.100607

N/A

0.641DataRank · unranked

71 citations

Michael G. Heckman, Launia J. White, Austin M. Veire, Otto Pedraza, Alexander R. Burch +77 more

Sex differences in the clinical manifestation of autosomal dominant frontotemporal dementia

Alzheimer s & Dementia(2025)10.1002/alz.14630

N/A

0.570DataRank · unranked

13 citations

Adam M. Staffaroni, Ignacio Ilan‐Gala, J. García Castro, John Kornak, Carmela M. Tartaglia +40 more

Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2023)10.1002/dad2.12423

N/A

0.442DataRank · unranked

18 citations

Hilary W. Heuer, Annie L Clark, Amy B. Wise, Masood Manoochehri, Leah K. Forsberg +37 more

Genome‐wide association studies identify novel loci in rapidly progressive Alzheimer's disease

Alzheimer s & Dementia(2024)10.1002/alz.13655

N/A

0.406DataRank · unranked

14 citations

Audrey Lynn, Kristy Miskimen, Yeunjoo E. Song, Thomas Wısnıewskı, Mark L. Cohen +4 more

Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study

JMIR Aging(2024)10.2196/52831

N/A

0.373DataRank · unranked

11 citations

Kaitlin B. Casaletto, Annie L Clark, Jack C. Taylor, Hilary W. Heuer, Amy B. Wise +44 more

Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes

Brain(2025)10.1093/brain/awaf032

N/A

0.360DataRank · unranked

10 citations

Elizabeth Hill, Tijs Watzeels, Holger Hummerich, Tracy Campbell, Lee Darwent +38 more

Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia

Alzheimer s & Dementia(2023)10.1002/alz.12898

N/A

0.345DataRank · unranked

9 citations

Yann Cobigo, Patrick Callahan, Brian S. Appleby, Danielle Brushaber, Kimiko Domoto‐Reilly +26 more

Efficient transmission of human prion diseases to a glycan-free prion protein-expressing host

Brain(2023)10.1093/brain/awad399

N/A

0.269DataRank · unranked

5 citations

Ignazio Calì, Mark L. Cohen, Rabail Aslam, Silvio Notari, Qingzhong Kong +5 more

FDG‐PET patterns associate with survival in patients with prion disease

Annals of Clinical and Translational Neurology(2024)10.1002/acn3.52230

N/A

0.208DataRank · unranked

3 citations

Yoav Piura, Brian S. Appleby, Dror Shir, Leland R Barnard, Venkatsampath Gogineni +3 more

Mortality of individuals with antemortem genetic testing for PRNP variants in the United States, 1998-2024

medRxiv(2025)10.1101/2025.10.03.25337271

Top 78%

0.104DataRank

Top 78%1 citations

Keisi Kotobelli, Kathleen Glisic, Daniel A Sprague, Sonia M. Vallabh, Brian S. Appleby +2 more

Neuropathologically-directed profiling of PRNP somatic and germline variants in sporadic human prion disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.25.600668

N/A

0.104DataRank · unranked

1 citations

Yuchen Cheng, Katherine Morillo, Ryan N. Doan, Connor Kenny, Aaron Foutz +8 more

The Phenotypic Spectrum of Sporadic Creutzfeldt‐Jakob Disease Cortical Subtype

Annals of Neurology(2025)10.1002/ana.78117

Top 78%

0.104DataRank

Top 78%1 citations

Claudia Marina Vargiu, Brian S. Appleby, Marcelo A. Barria, Giuseppe Mario Bentivenga, Ignazio Calì +12 more

Two distinct conformers of PrPD type 1 of sporadic Creutzfeldt–Jakob disease with codon 129VV genotype faithfully propagate in vivo

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01132-7

N/A

0DataRank · unranked

28 citations

Juan Carlos Espinosa, Satish Kumar Nemani, Alba Marín‐Moreno, Manuel V. Camacho, Rabail Aslam +5 more

ASLPrep: a platform for processing of arterial spin labeled MRI and quantification of regional brain perfusion

Nature Methods(2022)10.1038/s41592-022-01458-7

N/A

0DataRank · unranked

49 citations

Maxwell A. Bertolero, Sudipto Dolui, Matthew Cieslak, Kristin Murtha, Erica B. Baller +94 more

Atypical Case of VV1 Creutzfeldt–Jakob Disease Subtype: Case Report

Frontiers in Neurology(2022)10.3389/fneur.2022.875370

N/A

0DataRank · unranked

6 citations

Brian S. Appleby, Ignazio Calì, Hamid Okhravi, Adrianna E. Carrasco

A novel subtype of sporadic Creutzfeldt–Jakob disease with PRNP codon 129MM genotype and PrP plaques

Acta Neuropathologica(2023)10.1007/s00401-023-02581-1

N/A

0DataRank · unranked

28 citations

Christina D. Orrú, Rabail Aslam, Yvonne Cohen, Amelia Silva-Rohwer, Seongki Lee +9 more

Recognition memory and divergent cognitive profiles in prodromal genetic frontotemporal dementia

Cortex(2021)10.1016/j.cortex.2021.03.006

N/A

0DataRank · unranked

39 citations

Masood Manoochehri, Sandra Rizer, Brian S. Appleby, Danielle Brushaber, Sheena I. Dev +29 more

Detection of prions in the urine of patients affected by sporadic Creutzfeldt–Jakob disease

Annals of Clinical and Translational Neurology(2023)10.1002/acn3.51919

N/A

0DataRank · unranked

14 citations

Frank Ramirez, Adam Lyon, Paul E. Schulz, Brian S. Appleby, Fabio Moda +5 more

Network Connectivity Alterations across the MAPT Mutation Clinical Spectrum

Annals of Neurology(2023)10.1002/ana.26738

N/A

0DataRank · unranked

7 citations

Taru Flagan, Suvi Häkkinen, Stephanie A. Chu, Jesse A. Brown, Alex J. Lee +37 more

Phenotypic diversity of genetic Creutzfeldt–Jakob disease: a histo-molecular-based classification

Acta Neuropathologica(2021)10.1007/s00401-021-02350-y

N/A

0DataRank · unranked

57 citations

Marcello Rossi, Angela Mammana, Brian S. Appleby, Marcelo A. Barria, Ignazio Calì +14 more

Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01175-w

N/A

0DataRank · unranked

221 citations

Wen Wang, Steven A. Gunzler, Alexandra LeFevre, Zerui Wang, Alan J. Lerner +10 more

Novel histotypes of sporadic Creutzfeldt–Jakob disease linked to 129MV genotype

Acta Neuropathologica Communications(2023)10.1186/s40478-023-01631-9

N/A

0DataRank · unranked

4 citations

Gianfranco Puoti, Antonio Cornacchia, Katie Glisic, Seongki Lee, Zerui Wang +4 more

Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration

JAMA Network Open(2024)10.1001/jamanetworkopen.2024.4266

N/A

0DataRank · unranked

21 citations

Annie L Clark, Jack C. Taylor, Hilary W. Heuer, Mark Sanderson‐Cimino, Amy B. Wise +72 more

Large-scale validation of skin prion seeding activity as a biomarker for diagnosis of prion diseases

Acta Neuropathologica(2024)10.1007/s00401-023-02661-2

N/A

0DataRank · unranked

18 citations

Christina D. Orrú, Aaron Foutz, Mingxuan Ding, Jue Yuan, Syed Zahid Ali Shah +21 more

Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease

The Lancet Neurology(2021)10.1016/s1474-4422(20)30477-4

N/A

0DataRank · unranked

346 citations

Brian S. Appleby, Jean‐Philippe Brandel, Byron Caughey, Steven Collins, Michael D. Geschwind +14 more

A novel mechanism of phenotypic heterogeneity in Creutzfeldt-Jakob disease

Acta Neuropathologica Communications(2020)10.1186/s40478-020-00966-x

N/A

0DataRank · unranked

42 citations

Xiangzhu Xiao, Ignazio Calì, Laura Cracco, Gianfranco Puoti, M. Nigro +8 more

Gene-Specific Effects on Brain Volume and Cognition of TMEM106B in Frontotemporal Lobar Degeneration

Neurology(2024)10.1212/wnl.0000000000209832

N/A

0DataRank · unranked

7 citations

Eliana Marisa Ramos, Nick Corriveau‐Lecavalier, Vijay K. Ramanan, John Kornak, Carly Mester +50 more

Multi-shell diffusion MRI of the fornix as a biomarker for cognition in Alzheimer's disease

Magnetic Resonance Imaging(2024)10.1016/j.mri.2024.03.030

N/A

0DataRank · unranked

6 citations

Katherine Koenig, Alan J. Lerner, Brian S. Appleby, Paula Ogrocki, Jagan A. Pillai +4 more

Neuropathologically directed profiling of PRNP somatic and germline variants in sporadic human prion disease

Acta Neuropathologica(2024)10.1007/s00401-024-02774-2

N/A

0DataRank · unranked

3 citations

Yuchen Cheng, Katherine Morillo, Ryan N. Doan, Zinan Zhou, Connor Kenny +9 more

Subtype Diagnosis of Sporadic Creutzfeldt–Jakob Disease with Diffusion Magnetic Resonance Imaging

Annals of Neurology(2020)10.1002/ana.25983

N/A

0DataRank · unranked

54 citations

Riccardo Pascuzzo, Janis Blevins, Marco Moscatelli, Marina Grisoli, Raffaele Lodi +8 more

Psychotropic medication usage in sporadic versus genetic behavioral‐variant frontotemporal dementia

Alzheimer s & Dementia(2024)10.1002/alz.14448

N/A

0DataRank · unranked

1 citations

Nico Dimal, Kasey Cortez, Hilary W. Heuer, Leah K. Forsberg, Brian S. Appleby +32 more

Variably protease-sensitive prionopathy: mass spectrometry analysis of the pathogenic prion protein provides a new perspective

Acta Neuropathologica Communications(2025)10.1186/s40478-025-02079-9

N/A

0DataRank · unranked

1 citations

Xinxin Xiao, Silvio Notari, Ignazio Calì, Kristina Lundberg, Laura Cracco +5 more

Multiomic Analyses Direct Hypotheses for Creutzfeldt-Jakob Disease Risk Genes

medRxiv(2024)10.1101/2024.07.19.24310476

N/A

0DataRank · unranked

0 citations

Elizabeth Hill, Tijs Watzeels, Holger Hummerich, Tracy Campbell, Lee Darwent +38 more

Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers

Alzheimer s & Dementia(2024)10.1002/alz.14172

N/A

0DataRank · unranked

0 citations

Hyun Woo Lee, Emily W. Paolillo, Ging‐Yuek Robin Hsiung, Adam M. Staffaroni, Rowan Saloner +29 more

Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study

UNC Libraries(2024)10.17615/vrqb-zm35

N/A

0DataRank · unranked

0 citations

ALLFTD Consortium, John Kornak, Andrea Bozoki, Annie L Clark, Jack C. Taylor +45 more

Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disorders

Molecular Neurodegeneration(2025)10.1186/s13024-025-00821-4

N/A

0DataRank · unranked

19 citations

Linn Öijerstedt, Michael G. Heckman, Launia J. White, Hilary W. Heuer, Argentina Lario Lago +37 more

Co-existence of PrPD types 1 and 2 in sporadic Creutzfeldt-Jakob disease of the VV subgroup: phenotypic and prion protein characteristics

Scientific Reports(2020)10.1038/s41598-020-58446-0

N/A

0DataRank · unranked

57 citations

Gianfranco Puoti, Jason Smucny, Paul Michael Curtiss, Laura Cracco, Tetsuyuki Kitamoto +5 more

Prion propagation estimated from brain diffusion MRI is subtype dependent in sporadic Creutzfeldt–Jakob disease

Acta Neuropathologica(2020)10.1007/s00401-020-02168-0

N/A

0DataRank · unranked

62 citations

Neil P. Oxtoby, Alexandra L. Young, Janis Blevins, Gianmarco Castelli, Sara Garbarino +7 more

Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers

Annals of Clinical and Translational Neurology(2025)10.1002/acn3.70170

N/A

0DataRank · unranked

2 citations

Stephanie A. Chu, Suvi Häkkinen, Liwen Zhang, David McFall, Jonathan D. Rohrer +41 more

Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study

The Lancet Neurology(2020)10.1016/s1474-4422(20)30273-8

N/A

0DataRank · unranked

78 citations

Holger Hummerich, Emmanuelle Viré, James Uphill, Athanasios Dimitriadis, Helen E. Speedy +60 more

Protein co-aggregates of dense core amyloid plaques and CSF differ in rapidly progressive Alzheimer’s disease and slower sporadic Alzheimer’s disease

Alzheimer s Research & Therapy(2025)10.1186/s13195-025-01767-x

N/A

0DataRank · unranked

3 citations

Masaru Miyagi, Xinglong Wang, Brian S. Appleby, James B. Leverenz, Jagan A. Pillai +1 more

Search for a genetic cause of variably protease-sensitive prionopathy

PLoS Pathogens(2025)10.1371/journal.ppat.1013343

N/A

0DataRank · unranked

2 citations

Keisi Kotobelli, Stacey Hall, Michael E. Talkowski, Anne H. O’Donnell-Luria, Sonia M. Vallabh +3 more

Characterization of Prion Disease Associated with a Two-Octapeptide Repeat Insertion

Viruses(2021)10.3390/v13091794

N/A

0DataRank · unranked

7 citations

Ignazio Calì, Tze How Mok, Helen E. Speedy, Laszlo L. P. Hosszu, Christiane Stehmann +8 more

Temporal order of clinical and biomarker changes in familial frontotemporal dementia

Nature Medicine(2022)10.1038/s41591-022-01942-9

N/A

0DataRank · unranked

138 citations

Melanie Quintana, Barbara Wendelberger, Hilary W. Heuer, Lucy L. Russell, Yann Cobigo +95 more

Brian S. Appleby

Indexed papers

Top data-sharing exemplar

Papers