Benjamin Izar

Columbia University Irving Medical Center

MedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

13.1Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Nature Medicine(2020)10.1038/s41591-020-0844-1

Top 4%

5.6DataRank

Top 4%819 citations

Caroline B. M. Porter, Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro +45 more

Papers

Driven by 62 papers — median percentile 90. Top paper: “COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets”.

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

Nature(2021)10.1038/s41586-021-03570-8

N/A

10.7DataRank · unranked

879 citations

Carly G.K. Ziegler, Graham Heimberg, Rachelly Normand, Yiming Yang, Åsa Segerstolpe +95 more

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

Cell(2017)10.1016/j.cell.2017.06.016

N/A

8.4DataRank · unranked

191 citations

Mayte Suárez-Fariñas, Benjamin Izar, Ruth Dannenfelser, Itay Tirosh, Yong Liu +28 more

Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0387

N/A

6.9DataRank · unranked

289 citations

Mercedes A. Duran Paez, Ninjit Dhanota, Walid K. Chatila, Sarah E. Bettigole, John Y. H. Kwon +36 more

Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion

Nature Genetics(2021)10.1038/s41588-021-00779-1

N/A

6.5DataRank · unranked

271 citations

Johannes C. Melms, Pratiksha I. Thakore, Kathryn Geiger-Schuller, Patricia Ho, Adrienne Luoma +17 more

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Nature Medicine(2020)10.1038/s41591-020-0844-1

Top 4%

5.6DataRank

Top 4%819 citations

Caroline B. M. Porter, Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro +45 more

A molecular single-cell lung atlas of lethal COVID-19

Nature(2021)10.1038/s41586-021-03569-1

Top 4%

5.3DataRank

Top 4%737 citations

Jana Biermann, Huachao Huang, Yiping Wang, Ajay Nair, Somnath Tagore +39 more

Transcriptional mediators of treatment resistance in lethal prostate cancer

Nature Medicine(2021)10.1038/s41591-021-01244-6

N/A

4.8DataRank · unranked

196 citations

Michael S. Cuoco, Jett Crowdis, Alice Bosma-Moody, Zhenwei Zhang, Kevin Bi +35 more

Evolution of delayed resistance to immunotherapy in a melanoma responder

Nature Medicine(2021)10.1038/s41591-021-01331-8

N/A

3.6DataRank · unranked

137 citations

Jia‐Ren Lin, Emily Robitschek, Gyulnara G. Kasumova, Alex Heyde, Alvin Shi +35 more

Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma

Nature Medicine(2021)10.1038/s41591-020-01212-6

N/A

3.5DataRank · unranked

127 citations

Cyril Neftel, Marni E. Shore, Hannah R. Weisman, Nathan D. Mathewson, Matthew J. McBride +50 more

A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors

bioRxiv (Cold Spring Harbor Laboratory)(2019)10.1101/761429

N/A

2.5DataRank · unranked

68 citations

Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro, Indresh Singh +44 more

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health

Nature Aging(2022)10.1038/s43587-022-00326-5

N/A

2.1DataRank · unranked

128 citations

Patty J. Lee, Christopher C. Benz, Philip D. Blood, Katy Börner, Judith Campisi +93 more

The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity

Cancer Cell(2023)10.1016/j.ccell.2023.05.014

N/A

1.8DataRank · unranked

96 citations

Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Joanna Poźniak, Shivem B. Shah +28 more

Microenvironmental Landscape of Human Melanoma Brain Metastases in Response to Immune Checkpoint Inhibition

Cancer Immunology Research(2022)10.1158/2326-6066.cir-21-0870

N/A

1.6DataRank · unranked

53 citations

Samuel C. Markson, Jackson H. Stocking, Naema Nayyar, Matt Lastrapes, Matthew R. Strickland +40 more

Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas

Molecular Cell(2022)10.1016/j.molcel.2022.09.007

N/A

1.6DataRank · unranked

58 citations

Elizabeth M. Goldberg, Xiao Chen, Xinjing Xu, John T. McGuire, Giuseppe Leuzzi +16 more

Immunosuppressive Myeloid Cells Induce Nitric Oxide–Dependent DNA Damage and p53 Pathway Activation in CD8+ T Cells

Cancer Immunology Research(2021)10.1158/2326-6066.cir-20-0085

N/A

1.4DataRank · unranked

44 citations

Shengbao Suo, S Badrinath, Sushil Kumar, Johannes C. Melms, Adrienne Luoma +6 more

Micronuclear collapse from oxidative damage

Science(2024)10.1126/science.adj8691

N/A

1.3DataRank · unranked

71 citations

Yanyang Chen, Albert S. Agustinus, Alice Mazzagatti, Mercedes A. Duran Paez, Matthew Deyell +27 more

Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens

Nature Genetics(2023)10.1038/s41588-022-01268-9

Top 16%

1.3DataRank

Top 16%59 citations

Joy Linyue Fan, Johannes C. Melms, Amit Dipak Amin, Yohanna Georgis, Irving Barrera +20 more

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Science(2016)10.1126/science.aad0501

N/A

1.3DataRank · unranked

5121 citations

Benjamin Izar, Sanjay M. Prakadan, Marc H. Wadsworth, Daniel Treacy, John J. Trombetta +39 more

Contribution of Trp63CreERT2-labeled cells to alveolar regeneration is independent of tuft cells

eLife(2022)10.7554/elife.78217

N/A

1.1DataRank · unranked

28 citations

Yinshan Fang, Ming Jiang, Yihan Zhang, Jana Biermann, Johannes C. Melms +18 more

Transcriptional mediators of treatment resistance in lethal prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.19.998450

N/A

1.0DataRank · unranked

26 citations

Michael S. Cuoco, Jett Crowdis, Alice Bosma-Moody, Zhenwei Zhang, Kevin Bi +22 more

Spatially organized multicellular immune hubs in human colorectal cancer

Cell(2021)10.1016/j.cell.2021.08.003

N/A

1.0DataRank · unranked

787 citations

Matan Hofree, Siranush Sarkizova, Joshua D. Pirl, Vjola Jorgji, Alborz Bejnood +73 more

A single-cell landscape of high-grade serous ovarian cancer

Nature Medicine(2020)10.1038/s41591-020-0926-0

N/A

0.938DataRank · unranked

518 citations

Itay Tirosh, Elizabeth H. Stover, Isaac Wakiro, Michael S. Cuoco, Idan Alter +30 more

Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens

Nature Biotechnology(2024)10.1038/s41587-024-02235-x

N/A

0.896DataRank · unranked

36 citations

Parin Shah, Neeharika Kothapalli, Shivem B. Shah, Gergő Nikolényi, D. Zack Brodtman +12 more

Pan-cancer human brain metastases atlas at single-cell resolution

Cancer Cell(2025)10.1016/j.ccell.2025.03.025

Top 23%

0.860DataRank

Top 23%36 citations

Jian Zhong, Jana Biermann, Hao Duan, Xinyu Zhang, Yu Shi +23 more

Non-cell-autonomous cancer progression from chromosomal instability

Nature(2023)10.1038/s41586-023-06464-z

N/A

0.852DataRank · unranked

292 citations

Melissa J. Hubisz, Ethan M. Earlie, Mercedes A. Duran Paez, Christy Hong, Austin Varela +20 more

Dissecting the treatment-naive ecosystem of human melanoma brain metastasis

Cell(2022)10.1016/j.cell.2022.06.007

N/A

0.807DataRank · unranked

216 citations

Johannes C. Melms, Amit Dipak Amin, Yiping Wang, Lindsay Caprio, Alcida Karz +54 more

KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response

Journal for ImmunoTherapy of Cancer(2023)10.1136/jitc-2023-006782

N/A

0.776DataRank · unranked

21 citations

Mingxuan Zhang, Matthew G. Chaimowitz, Shruti Bansal, Somnath Tagore, Aleksandar Obradović +9 more

SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion

Cell(2024)10.1016/j.cell.2024.01.008

N/A

0.689DataRank · unranked

98 citations

Alessandro Vasciaveo, Angelo Taglialatela, Xiao Chen, Tessa M. Firestone, Allison R. Hickman +28 more

A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.27.514070

N/A

0.677DataRank · unranked

16 citations

Dimitra Karagkouni, Nikolaos Kalavros, Johannes C. Melms, Sebastian Niezen, Toni Marie Delorey +63 more

An activation to memory differentiation trajectory of tumor-infiltrating lymphocytes informs metastatic melanoma outcomes

Cancer Cell(2022)10.1016/j.ccell.2022.04.005

N/A

0.617DataRank · unranked

60 citations

Akanksha Verma, Ruth Dannenfelser, Marit Melssen, Itay Tirosh, Benjamin Izar +19 more

Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation

Nature Cancer(2024)10.1038/s43018-023-00704-x

N/A

0.464DataRank · unranked

21 citations

Tyler J. Aprati, Wei-Yu Chi, Johannes C. Melms, Clemens Hug, Stephanie H. Davis +40 more

Scalable generation and functional classification of genetic variants in inborn errors of immunity to accelerate clinical diagnosis and treatment

Cell(2025)10.1016/j.cell.2025.05.037

N/A

0.396DataRank · unranked

13 citations

Chris J. Frangieh, Neeharika Kothapalli, Jay A. Levy, Clarissa Heck, Johannes C. Melms +11 more

B-cells Drive Response to PD-1 Blockade in Glioblastoma Upon Neutralization of TGFβ-mediated Immunosuppression

Research Square(2023)10.21203/rs.3.rs-2399170/v1

N/A

0.385DataRank · unranked

7 citations

Brandyn Castro, Mark Dapash, Andrew Zolp, Joshua Katz, Víctor A. Arrieta +24 more

Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.01.267211

N/A

0.375DataRank · unranked

5 citations

Johannes C. Melms, Pratiksha I. Thakore, Kathryn R. Geiger-Schuller, Patricia Ho, Adrienne Luoma +15 more

A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients

Genome Biology(2025)10.1186/s13059-025-03499-5

N/A

0.363DataRank · unranked

7 citations

Dimitra Karagkouni, Nikolaos Kalavros, Johannes C. Melms, Sebastian Niezen, Toni Marie Delorey +70 more

The CD58:CD2 axis is co-regulated with PD-L1 via CMTM6 and governs anti-tumor immunity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.21.485049

N/A

0.360DataRank · unranked

10 citations

Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Shivem B. Shah, Zachary Walsh +21 more

The evolving landscape of brain metastasis: volume II

Trends in cancer(2025)10.1016/j.trecan.2025.11.007

N/A

0.349DataRank · unranked

9 citations

Carey K. Anders, Adrienne Boire, Benjamin Izar, Nuria Kotecki, Srinivas Malladi +12 more

Smoother: a unified and modular framework for incorporating structural dependency in spatial omics data

Genome biology(2023)10.1186/s13059-023-03138-x

N/A

0.330DataRank · unranked

8 citations

Jean-Baptiste Reynier, Xi Fu, Guojie Zhong, Jiahao Jiang, Rydberg Supo Escalante +6 more

Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.30.426796

N/A

0.297DataRank · unranked

4 citations

Matan Hofree, Jonathan Chen, Siranush Sarkizova, Joshua D. Pirl, Vjola Jorgji +71 more

Smoother: A Unified and Modular Framework for Incorporating Structural Dependency in Spatial Omics Data

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.25.513785

N/A

0.208DataRank · unranked

3 citations

Jean-Baptiste Reynier, Xi Fu, Guojie Zhong, Jiahao Jiang, Rydberg Supo Escalante +6 more

Multi-modal single-cell and whole-genome sequencing of minute, frozen specimens to propel clinical applications

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.13.480272

N/A

0.208DataRank · unranked

3 citations

Joy Linyue Fan, Johannes C. Melms, Amit Dipak Amin, Yohanna Georgis, Patricia Ho +15 more

Single-cell RNA-sequencing and -imaging of melanoma ecosystems reveals sources of resistance to immune checkpoint blockade.

Journal of Clinical Oncology(2018)10.1200/jco.2018.36.15_suppl.3074

N/A

0.208DataRank · unranked

1 citations

Livnat Jerby-Arnon, Asaf Rotem, Parin Shah, David Liu, Gao Zhang +13 more

Unveiling Common Transcriptomic Features between Melanoma Brain Metastases and Neurodegenerative Diseases

Journal of Investigative Dermatology(2024)10.1016/j.jid.2024.09.005

N/A

0.165DataRank · unranked

2 citations

Alcida Karz, Marta R. Hidalgo, Borja Gómez-Cabañes, Adolfo López, José F. Català-Senent +10 more

KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.01.522340

N/A

0.104DataRank · unranked

1 citations

Mingxuan Zhang, Matthew G. Chaimowitz, Shruti Bansal, Aleksandar Obradović, Meri Rogava +7 more

The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.03.18.644053

N/A

0.104DataRank · unranked

1 citations

Alcida Karz, Maya Navarro, Victoria Osorio-Vasquez, Olga Katsara, Adam K. Walker +21 more

Phylogenetic analysis of longitudinal melanoma samples to reveal convergent evolution and markers of immunotherapy resistance.

Journal of Clinical Oncology(2018)10.1200/jco.2018.36.15_suppl.9581

N/A

0.104DataRank · unranked

1 citations

Gao Zhang, Alvin Shi, Benjamin Izar, Alexander Heyde, Gyulnara G. Kasumova +14 more

Data from Immunosuppressive Myeloid Cells Induce Nitric Oxide–Dependent DNA Damage and p53 Pathway Activation in CD8+ T Cells

(2023)10.1158/2326-6066.c.6550204.v1

N/A

0DataRank · unranked

0 citations

Shengbao Suo, S Badrinath, Sushil Kumar, Johannes C. Melms, Adrienne Luoma +6 more

Microenvironmental correlates of immune checkpoint inhibitor response in human melanoma brain metastases revealed by T cell receptor and single-cell RNA sequencing

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.25.456956

N/A

0DataRank · unranked

0 citations

Samuel C. Markson, Jackson H. Stocking, Naema Nayyar, Matthew Lastrapes, Matthew R. Strickland +39 more

Impact of Sequencing Radiation Therapy and Immune Checkpoint Inhibitors in the Treatment of Melanoma Brain Metastases

International Journal of Radiation Oncology*Biology*Physics(2020)10.1016/j.ijrobp.2020.01.043

N/A

0DataRank · unranked

44 citations

Tahseen H. Nasti, Benjamin Izar, Robert H. Press, Maxwell Xu, Lindsey Lowder +14 more

HTAPP_Processing human ovarian cancer ascites to a single-cell suspension for single-cell RNA-seq v1

(2019)10.17504/protocols.io.4kbgusn

N/A

0DataRank · unranked

0 citations

Parin Shah, Mei-Ju Su, Isaac Wakiro, Sara Napolitano, Jingyi Wu +7 more

Implementation of single-cell genomics as a translational tool in patients with metastatic melanoma.

Journal of Clinical Oncology(2016)10.1200/jco.2016.34.15_suppl.11503

N/A

0DataRank · unranked

0 citations

Itay Tirosh, Asaf Rotem, Parin Shah, Ken Dutton-Regester, Mohammad Fallahi +17 more

The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin

Molecular Cell(2025)10.1016/j.molcel.2025.03.026

N/A

0DataRank · unranked

7 citations

Christie B. Nguyen, Saul Carcamo, Valentina Kirigin Callaú, Shannon Moran, Dan Filipescu +8 more

Author Correction: Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I–III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial

Nature Communications(2024)10.1038/s41467-023-44575-3

N/A

0DataRank · unranked

0 citations

Zachary Walsh, Johannes C. Melms, Jeffery L. Port, Benjamin E. Lee, Abu Nasar +17 more

HTAPP_Processing human ovarian cancer ascites to a single-cell suspension for single-cell RNA-seq v2

(2020)10.17504/protocols.io.bhbkj2kw

N/A

0DataRank · unranked

0 citations

Parin Shah, Mei-Ju Su, Isaac Wakiro, Sara Napolitano, Jingyi Wu +7 more

BRIDGE- HTAPP_Depletion of CD45+ cells from ovarian cancer ascites single cell suspensions for single-cell RNA-Seq v1

(2019)10.17504/protocols.io.4cqgsvw

N/A

0DataRank · unranked

0 citations

Parin Shah, Mei-Ju Su, Isaac Wakiro, Sara Napolitano, Jingyi Wu +7 more

Large-scale CRISPR-Cas9 screens to define regulators of immune checkpoints

Methods in cell biology(2025)10.1016/bs.mcb.2025.10.011

N/A

0DataRank · unranked

1 citations

Johannes C. Melms, Patricia Ho, Benjamin Izar, Michael Mu

Massively scalable generation, discovery, and clinical (re-)classification of inborn errors of immunity using cutting-edge genome engineering 4011

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1746

N/A

0DataRank · unranked

0 citations

Chris J. Frangieh, Clarissa Heck, Sarah Grauman, Jared Pollard, Lei Huang +5 more

Multi-omic profiling reveals discrepant immunogenic properties and a unique tumor microenvironment among melanoma brain metastases

npj Precision Oncology(2023)10.1038/s41698-023-00471-z

N/A

0DataRank · unranked

24 citations

Jennifer R. Ribeiro, Jun Yin, Joanne Xiu, Matías A. Bustos, Fumito Ito +17 more

Cytometric assessment of antigen-specific T cell signaling

Methods in cell biology(2025)10.1016/bs.mcb.2025.11.003

N/A

0DataRank · unranked

0 citations

Shivem Shah, Johannes C. Melms, Benjamin Izar, Zachary H. Walsh

Multi-modal single-cell profiling of sarcomas from archival tissue reveals mechanisms of resistance to immune checkpoint inhibitors.

Journal of Clinical Oncology(2022)10.1200/jco.2022.40.16_suppl.e23518

N/A

0DataRank · unranked

0 citations

Sminu Bose, Amit Dipak Amin, Somnath Tagore, Johannes C. Melms, Simon Berhe +4 more

KINOMO: A non-negative matrix factorization framework for recovering intra- and inter-tumoral heterogeneity from single-cell RNA-seq data

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.02.490362

N/A

0DataRank · unranked

3 citations

Yiping Wang, Jana Biermann, Raúl Rabadán, Andrea Califano, Benjamin Izar +1 more

Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis

Nature(2022)10.1038/s41586-022-05289-6

N/A

0DataRank · unranked

336 citations

Yoshinobu Saito, Ajay Nair, Dianne H. Dapito, Le‐Xing Yu, Aashreya Ravichandra +33 more

Benjamin Izar

Indexed papers

Top data-sharing exemplar

Papers