Marcia C. Haigis

Also affiliated with Harvard University, Harvard University Press, Boston VA Research Institute, Dana-Farber/Harvard Cancer Center, Harvard Stem Cell Institute

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 48 papers. Top paper: “Metabolic modeling of single Th17 cells reveals regulators of autoimmunity”.

Metabolic modeling of single Th17 cells reveals regulators of autoimmunity

Cell(2021)10.1016/j.cell.2021.05.045

N/A

8.1DataRank · unranked

514 citations

Chao Wang, Johannes Fessler, David DeTomaso, Julián Ávila-Pacheco, James J. Kaminski +21 more

SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis

Cell Reports(2021)10.1016/j.celrep.2021.109345

N/A

1.7DataRank · unranked

66 citations

Haejin Yoon, Jessica B. Spinelli, Elizabeth R. Nunn, Gaëlle Laurent, Paulina Keskinidis +11 more

Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

Cell(2020)10.1016/j.cell.2020.11.009

N/A

0.999DataRank · unranked

778 citations

Jefte M. Drijvers, Gregory J. Baker, Alessia Catozzi, Juan Carlos García‐Cañaveras, Brandon M. Gassaway +17 more

Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity

Molecular Cell(2021)10.1016/j.molcel.2021.08.027

N/A

0.934DataRank · unranked

504 citations

Jillian L. Shaw, Marcia C. Haigis, Anna Greka, Haejin Yoon

Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

Cell Metabolism(2022)10.1016/j.cmet.2022.06.008

N/A

0.882DataRank · unranked

357 citations

Jared H. Rowe, Sheila Johnson, Shakchhi Joshi, Giulia Notarangelo, Kiran Kurmi +5 more

Age-associated remodeling of T cell immunity and metabolism

Cell Metabolism(2022)10.1016/j.cmet.2022.11.005

N/A

0.784DataRank · unranked

185 citations

Peter Georgiev, Alison E. Ringel, Arlene H. Sharpe, Marcia C. Haigis, SeongJun Han

Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells

Cancer Immunology Research(2020)10.1158/2326-6066.cir-20-0384

N/A

0.781DataRank · unranked

182 citations

Jacob E. Gillis, Tara Muijlwijk, Thao H. Nguyen, Emily F. Gaudiano, Isaac S. Harris +9 more

NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer

Cell Metabolism(2023)10.1016/j.cmet.2023.01.012

N/A

0.750DataRank · unranked

147 citations

Maolin Ge, Makiko Hayashi, Magdy Gohar, Cong-Hui Yao, Adriaan de Groot +22 more

In Silico Modeling of Metabolic State in Single Th17 Cells Reveals Novel Regulators of Inflammation and Autoimmunity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.23.912717

N/A

0.737DataRank · unranked

12 citations

Chao Wang, David DeTomaso, Julian Avila-Pacheco, Sarah Zaghouani, Johannes Fessler +17 more

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

Proceedings of the National Academy of Sciences(2012)10.1073/pnas.1115813109

N/A

0.698DataRank · unranked

104 citations

Jaewon Lee, Amanda Souza, Valérie Desquiret-Dumas, Kevin Bullock, Glenn C. Rowe +5 more

The effects of age and systemic metabolism on anti-tumor T cell responses

eLife(2020)10.7554/elife.62420

N/A

0.633DataRank · unranked

67 citations

Arlene H. Sharpe, Marcia C. Haigis, Jefte M. Drijvers

Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1301

N/A

0.596DataRank · unranked

52 citations

Ilaria Elia, Osmaan Shahid, Emily F. Gaudiano, Natalia E. Sifnugel, Sheila Johnson +11 more

Regulatory T cells in dominant immunologic tolerance

Journal of Allergy and Clinical Immunology(2023)10.1016/j.jaci.2023.09.025

N/A

0.550DataRank · unranked

38 citations

Mehdi Benamar, SeongJun Han, Marcia C. Haigis, Arlene H. Sharpe, Talal A. Chatila +1 more

Astrocyte deletion of α2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway

Nature Communications(2020)10.1038/s41467-020-19915-2

N/A

0.533DataRank · unranked

34 citations

Xiaoying Chen, Lindsey M. Brier, Jonathan Bumstead, Nicholas Rensing, Alison E. Ringel +13 more

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity

Cell Metabolism(2023)10.1016/j.cmet.2023.03.018

N/A

0.529DataRank · unranked

33 citations

Juliana Coraor, Choah Kim, Eriene-Heidi Sidhom, Matthew Brown, Jamie L. Marshall +33 more

Metabolic analyses reveal dysregulated NAD+ metabolism and altered mitochondrial state in ulcerative colitis

PLoS ONE(2022)10.1371/journal.pone.0273080

N/A

0.520DataRank · unranked

31 citations

Sarah A. Tucker, Silvia F. Quevedo, Aslihan Inal, Joshua R. Korzenik, Marcia C. Haigis +1 more

Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity

Cancer Immunology Research(2024)10.1158/2326-6066.cir-24-0463

N/A

0.477DataRank · unranked

23 citations

SeongJun Han, Amy Y. Huang, Thao H. Nguyen, Jefte M. Drijvers, Hannah Creasey +15 more

Nutrient control of growth and metabolism through mTORC1 regulation of mRNA splicing

Molecular Cell(2024)10.1016/j.molcel.2024.10.037

N/A

0.457DataRank · unranked

20 citations

Meltem Isik, Ziyun Wu, Kiran Kurmi, Meng Jin, Sungyun Cho +7 more

Transforming treatment paradigms: Focus on personalized medicine for high‐grade serous ovarian cancer

CA: A Cancer Journal for Clinicians(2025)10.3322/caac.70008

N/A

0.449DataRank · unranked

19 citations

Britta Lange, Kevin M. Elias, Marcia C. Haigis, Sylvia Mechsner, Elena Ioana Braicu +2 more

Development of a colorimetric α-ketoglutarate detection assay for prolyl hydroxylase domain (PHD) proteins

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100397

N/A

0.449DataRank · unranked

19 citations

Alison E. Ringel, William Yuan, Joao A. Paulo, Haejin Yoon, Mark A. Currie +2 more

GUK1 activation is a metabolic liability in lung cancer

Cell(2025)10.1016/j.cell.2025.01.024

N/A

0.449DataRank · unranked

19 citations

Kiran Kurmi, Yutong Dai, Ishita Dhiman, Shakchhi Joshi, Brandon M. Gassaway +21 more

Spatial regulation of glucose and lipid metabolism by hepatic insulin signaling

Cell Metabolism(2025)10.1016/j.cmet.2025.03.015

N/A

0.434DataRank · unranked

17 citations

Kyle D. Copps, Oliver Stöhr, Beikl Liu, Songhua Hu, Shakchhi Joshi +5 more

Metabolic and Epigenomic Regulation of Th17/Treg Balance by the Polyamine Pathway

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.23.911966

N/A

0.361DataRank · unranked

7 citations

Allon Wagner, Johannes Fessler, Julian Avila-Pacheco, Jim Karminski, Sarah Zaghouani +22 more

Metabolic modulation of mitochondrial mass during CD4+ T cell activation

Cell chemical biology(2023)10.1016/j.chembiol.2023.08.008

N/A

0.360DataRank · unranked

10 citations

Dan Liang, Robert van de Ven, Peter Georgiev, Brandon M. Gassaway, SeongJun Han +15 more

Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia

iScience(2021)10.1016/j.isci.2021.102651

N/A

0.345DataRank · unranked

9 citations

Kamrine E. Poels, Cong-Hui Yao, Kimihito C. Kawabata, Gongwei Wu, Cihangir Duy +17 more

Profiling Proteins and Phosphorylation Sites During T Cell Activation Using an Integrated Thermal Shift Assay

Molecular & Cellular Proteomics(2024)10.1016/j.mcpro.2024.100801

N/A

0.337DataRank · unranked

5 citations

Edward L. Huttlin, Emily M. Huntsman, Tomer M. Yaron-Barir, Jared L. Johnson, Kiran Kurmi +6 more

Integrated analysis of transcriptional and metabolic responses to mitochondrial stress

Cell Reports Methods(2025)10.1016/j.crmeth.2025.101027

N/A

0.269DataRank · unranked

5 citations

Songhua Hu, Sarah A. Boswell, Peter K. Sorger, Alison E. Ringel, Marcia C. Haigis +1 more

Immunometabolism at the crossroads of obesity and cancer—a Keystone Symposia report

Annals of the New York Academy of Sciences(2023)10.1111/nyas.14976

N/A

0.269DataRank · unranked

5 citations

Jeffrey C. Rathmell, Erika L. Pearce, Ping‐Chih Ho, Marcia C. Haigis, Murad R. Mamedov +24 more

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.19.529127

N/A

0.118DataRank · unranked

1 citations

Juliana Coraor, Choah Kim, Eriene-Heidi Sidhom, Matthew Brown, Jamie L. Marshall +33 more

The diabetes gene Tcf7l2 organizes gene expression in the liver and regulates amino acid metabolism

Molecular Metabolism(2025)10.1016/j.molmet.2025.102208

N/A

0.104DataRank · unranked

1 citations

William O’Connor, Pedro Henrique Vendramini, Mareike Schell, Kiran J. Biddinger, Matt Kanke +10 more

Branched-chain α-ketoacids aerobically activate HIF1α signalling in vascular cells

Nature Metabolism(2024)10.1038/s42255-024-01150-4

N/A

0DataRank · unranked

20 citations

Nishith Shrimali, Niv Vigder, William M. Oldham, Clary B. Clish, Huamei He +7 more

Metabolites and the tumour microenvironment: from cellular mechanisms to systemic metabolism

Nature Metabolism(2021)10.1038/s42255-020-00317-z

N/A

0DataRank · unranked

632 citations

Marcia C. Haigis, Ilaria Elia

SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis

Cell Reports(2024)10.1016/j.celrep.2024.113975

N/A

0DataRank · unranked

14 citations

Song-Hua Hu, Sejal Vyas, Albert Park, Shakchhi Joshi, Aslihan Inal +5 more

pLxIS-containing domains are biochemically flexible regulators of interferons and metabolism

Molecular Cell(2024)10.1016/j.molcel.2024.05.030

N/A

0DataRank · unranked

8 citations

Neha Chaudhary, Yun Chen Tien, Magdalena Rogozinska, Shakchhi Joshi, Cong-Hui Yao +7 more

PD-1 regulates tumor-infiltrating CD8+ T cells in both a cell-intrinsic and a cell-extrinsic fashion

The Journal of Experimental Medicine(2025)10.1084/jem.20230542

N/A

0DataRank · unranked

6 citations

Samuel C. Markson, Thomas S. Conway, Vikram R. Juneja, Osmaan Shahid, Kelly P. Burke +13 more

The Diabetes Gene Tcf7l2 Organizes Gene Expression in the Liver and Regulates Amino Acid Metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.03.647067

N/A

0DataRank · unranked

1 citations

William O’Connor, Pedro Henrique Vendramini, Mareike Schell, Kiran J. Biddinger, George Pengo +7 more

Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis

eLife(2025)10.7554/elife.107745

N/A

0DataRank · unranked

0 citations

Sheila Johnson, Kiran Kurmi, Song-Hua Hu, SeongJun Han, Dillon G. Patterson +10 more

Nitrogen Metabolism in Cancer and Immunity

Trends in Cell Biology(2020)10.1016/j.tcb.2020.02.005

N/A

0DataRank · unranked

161 citations

Marcia C. Haigis, Kiran Kurmi

Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers

PLoS ONE(2022)10.1371/journal.pone.0261803

N/A

0DataRank · unranked

16 citations

Jiska van der Reest, Walid M. Abdelmoula, Daniela Ruiz, Shakchhi Joshi, Alison E. Ringel +3 more

Dangerous dynamic duo: Lactic acid and PD-1 blockade

Cancer Cell(2022)10.1016/j.ccell.2022.01.008

N/A

0DataRank · unranked

20 citations

Marcia C. Haigis, Stephanie K. Dougan, Sheila Johnson

1038 Loss of PD-1 signals improves CD8+ TIL function in a cell intrinsic and cell extrinsic manner

Regular and Young Investigator Award Abstracts(2022)10.1136/jitc-2022-sitc2022.1038

N/A

0DataRank · unranked

0 citations

Kristen E. Pauken, Vikram R. Juneja, Osmaan Shahid, Kelly P. Burke, Jared H. Rowe +9 more

Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome

Nature Communications(2022)10.1038/s41467-022-32982-x

N/A

0DataRank · unranked

39 citations

Alexander A. Akerberg, Xiaoran Zhang, Haejin Yoon, Shakchhi Joshi, Celia Hallinan +6 more

Characterization of metabolic compartmentalization in the liver using spatially resolved metabolomics

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.13.472421

N/A

0DataRank · unranked

0 citations

Sylwia A. Stopka, Walid M. Abdelmoula, Daniela Ruiz, Shakchhi Joshi, Alison E. Ringel +3 more

Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis

Molecular Cell(2023)10.1016/j.molcel.2023.03.023

N/A

0DataRank · unranked

43 citations

Joon Seok Park, Kiran Kurmi, Songhua Hu, Giulia Notarangelo, Joseph M. Crowley +5 more

Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis

Science(2021)10.1126/science.aaz2740

N/A

0DataRank · unranked

49 citations

Karen Hoi, Victoria Chan, Brian J. Abraham, Song Yang, James Mullahoo +23 more

Chemical QuantArray: A Quantitative Tool for Mass Spectrometry Imaging

Analytical Chemistry(2023)10.1021/acs.analchem.3c00803

N/A

0DataRank · unranked

19 citations

Daniela Ruiz, Gerard Baquer, Clément Bodineau, Md Amin Hossain, Valentina T. Pellens +9 more

Data from Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells

(2023)10.1158/2326-6066.c.6550425.v1

N/A

0DataRank · unranked

0 citations

Jacob E. Gillis, Tara Muijlwijk, Thao H. Nguyen, Emily F. Gaudiano, Isaac S. Harris +9 more

The aging lung: Physiology, disease, and immunity

Cell(2021)10.1016/j.cell.2021.03.005

N/A

0DataRank · unranked

483 citations

Jared H. Rowe, Carolina Garcia-de-Alba, Carla F. Kim, Arlene H. Sharpe, Marcia C. Haigis +1 more