Mark Hedglin

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 18 papers. Top paper: “Cryo-EM structure of apo-form human DNA polymerase δ elucidates its minimal DNA synthesis activity without PCNA”.

Cryo-EM structure of apo-form human DNA polymerase δ elucidates its minimal DNA synthesis activity without PCNA

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108342

N/A

0.177DataRank · unranked

2 citations

Mark Hedglin, Katsuhiko Murakami, Yeonoh Shin

PCNA monoubiquitination is regulated by diffusion of Rad6/Rad18 complexes along RPA filaments

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.11.247064

N/A

0.165DataRank · unranked

2 citations

Bhaswati Sengupta, Stephen J. Benkovic, Tae-Hee Lee, Mark Hedglin, Mingjie Li

Replicative DNA polymerase epsilon and delta holoenzymes show wide-ranging inhibition at G-quadruplexes in the human genome

Nucleic Acids Research(2025)10.1093/nar/gkaf352

N/A

0.165DataRank · unranked

2 citations

Matthias H. Weissensteiner, Kara G Pytko, Joseph M. Dahl, Eduard Kejnovský, Iva Kejnovská +5 more

Chemotherapeutic 6-thio-2’-deoxyguanosine selectively targets and inhibits telomerase by inducing a non-productive telomere-bound telomerase complex

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.05.636339

N/A

0.104DataRank · unranked

1 citations

Mareike Badstübner, Michael H. Gerber, William Mannherz, Noah Lampl, Rachel L. Dannenberg +9 more

PARP2 promotes Break Induced Replication-mediated telomere fragility in response to replication stress

Nature Communications(2024)10.1038/s41467-024-47222-7

N/A

0DataRank · unranked

20 citations

Natalie Laspata, Rachel L. Dannenberg, Caroline Curry, Simone Darkoa-Larbi, Mark Hedglin +3 more

Replication protein A dynamically re-organizes on primer/template junctions to permit DNA polymerase δ holoenzyme assembly and initiation of DNA synthesis

Nucleic Acids Research(2024)10.1093/nar/gkae475

N/A

0DataRank · unranked

12 citations

Lindsey O. Rogers, Kara G Pytko, Rachel L. Dannenberg, Samuel Perreault, Vikas Kaushik +4 more

Direct, ensemble FRET approaches to monitor transient state kinetics of human DNA polymerase δ holoenzyme assembly and initiation of DNA synthesis

Methods in enzymology on CD-ROM/Methods in enzymology(2024)10.1016/bs.mie.2024.08.002

N/A

0DataRank · unranked

6 citations

Mark Hedglin, Jessica L. Norris

Replication of [AT/TA] 25 Microsatellite Sequences by Human DNA Polymerase δ Holoenzymes Is Dependent on dNTP and RPA Levels

Biochemistry(2024)10.1021/acs.biochem.4c00006

N/A

0DataRank · unranked

3 citations

Rachel L. Dannenberg, Kristin A. Eckert, Mark Hedglin, Kara G. Pytko

Structure of the human CTF18–RFC clamp loader bound to PCNA

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.08.593111

N/A

0DataRank · unranked

1 citations

Muhammad Tehseen, Amani Al-Amodi, Grace Young, Ammar Usman Danazumi, Phong Quoc Nguyen +5 more

Structure of the human CTF18−RFC clamp loader bound to PCNA

eLife(2024)10.7554/elife.103493

N/A

0DataRank · unranked

0 citations

Muhammad Tehseen, Amani Al-Amodi, Grace Young, Ammar U Danazumi, Phong Quoc Nguyen +5 more

Therapeutic 6-thio-deoxyguanosine inhibits telomere elongation in cancer cells by inducing a non-productive stalled telomerase complex

Nature Communications(2025)10.1038/s41467-025-66534-w

N/A

0DataRank · unranked

4 citations

Mareike Badstübner, Michael H. Gerber, William Mannherz, Noah Lampl, Rachel L. Dannenberg +9 more

A human high-fidelity DNA polymerase holoenzyme has a wide range of lesion bypass activities

Nucleic Acids Research(2025)10.1093/nar/gkaf646

N/A

0DataRank · unranked

1 citations

Joseph A. Cardina, Helen Washington, Shijun Gao, Marc M. Greenberg, Mark Hedglin +1 more

Structure of the human CTF18−RFC clamp loader bound to PCNA

eLife(2025)10.7554/elife.103493.2

N/A

0DataRank · unranked

0 citations

Muhammad Tehseen, Amani Al-Amodi, Grace Young, Ammar Usman Danazumi, Phong Quoc Nguyen +5 more

Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase

Nucleic Acids Research(2020)10.1093/nar/gkz1221

N/A

0DataRank · unranked

15 citations

Mark Hedglin, Katsuhiko Murakami, Yeonoh Shin

PCNA encircling primer/template junctions is eliminated by exchange of RPA for Rad51: implications for the interplay between human DNA damage tolerance pathways

Nucleic Acids Research(2025)10.1093/nar/gkaf1478

N/A

0DataRank · unranked

0 citations

Lindsey O. Rogers, Grace Young, Kara G Pytko, Rachel L. Dannenberg, Samuel Perreault +4 more

Tracking of progressing human DNA polymerase δ holoenzymes reveals distributions of DNA lesion bypass activities

Nucleic Acids Research(2022)10.1093/nar/gkac745

N/A

0DataRank · unranked

9 citations

Joseph A. Cardina, Kara G Pytko, Mark Hedglin, Rachel L. Dannenberg

Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics

Nucleic Acids Research(2023)10.1093/nar/gkad481

N/A

0DataRank · unranked

32 citations

Jessica Norris, Thu H. Khoang, Vikas Kaushik, Rahul Chadda, Edwin Antony +3 more

Replication of [AT/TA] 25 microsatellite sequences by human DNA polymerase δ holoenzymes is dependent on dNTP and RPA levels

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.07.566133

N/A

0DataRank · unranked

0 citations

Rachel L. Dannenberg, Kristin A. Eckert, Mark Hedglin, Kara G. Pytko